Heparin combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Generalised Other Serious 11/9/2005 Female 1/6/2006 Pharmacist Canada
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 10/16/2005 85 Male 137 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Dehydration Hospitalization 9/16/2005 61 Female 2/13/2006 Other Health Professional United States
Primary
Concomitant
Nosocomial Infection Hospitalization 2/20/2006 72 Male 220 lb 2/21/2006 Other Health Professional United States
Primary
Secondary
Thrombosis Required Intervention 62 Female 2/27/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 3/8/2006 Netherlands
Primary
Secondary
Concomitant
Stress Hospitalization 12/12/2005 39 Female 170 lb 1/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Stress Hospitalization 12/12/2005 39 Female 170 lb 1/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pericardial Effusion Required Intervention 5 Male 4/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 11/9/2005 Female 5/16/2006 Pharmacist Canada
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 12/3/2005 77 Female 97 lb 5/16/2006 Pharmacist United States
Primary
Secondary
Pain In Extremity 54 Male 362 lb 4/6/2006 Pharmacist United States
Primary
Concomitant
Wound Secretion Other Serious 8/1/2004 74 Female 114 lb 6/29/2006 United States
Primary
Secondary
Concomitant
Intracranial Haematoma Required Intervention 7/5/2006 85 Male 143 lb 7/5/2006 Pharmacist United States
Primary
Secondary
Neutropenia Hospitalization 6/9/2006 68 Male 7/17/2006 Physician France
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 7/18/2006 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Wheezing Other Serious 11/1/2003 67 Female 113 lb 7/18/2005 Pharmacist United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 6/1/2006 51 Male 175 lb 7/27/2006 United States
Primary
Concomitant
Vomiting Hospitalization 52 Female 8/3/2006 Other Health Professional Singapore
Primary
Concomitant
Vomiting Other Serious 52 Female 8/11/2006 Other Health Professional Canada
Primary
Secondary
Post Procedural Complication Hospitalization 5/30/2006 69 Male 8/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 7/8/2004 45 Female 231 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/24/2006 Male 101 lb 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/24/2006 Male 101 lb 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/24/2006 65 Male 9/19/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 51 Male 9/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Vocal Cord Paralysis Other Serious 5/1/2006 81 Female 9/27/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Other Serious 9/12/2006 2 Male 10/13/2006 Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/29/2005 63 Male 10/25/2006 Physician Japan
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 115 lb 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 9/13/2006 45 Male 268 lb 9/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 5/1/2006 51 Male 175 lb 10/24/2006 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2006 82 Male 11/3/2006 Physician Japan
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 Female 11/9/2006 Consumer Germany
Primary
Secondary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 58 Male 12/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Skin Necrosis Other Serious 58 Male 11/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Vocal Cord Paralysis Other Serious 5/1/2006 81 Female 11/28/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/28/2006 77 Female 88 lb 12/15/2006 Other Health Professional France
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 10/8/2006 79 Male 181 lb 12/20/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 60 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 65 Female 110 lb 12/18/2006 Physician Japan
Primary
Concomitant
Anal Fissure Hospitalization 10/8/2006 79 Male 181 lb 12/28/2006 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 32 Female 1/9/2007 Consumer United States
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 7/28/2006 77 Female 88 lb 1/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/20/2004 54 Female 140 lb 1/19/2007 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/18/2004 54 Female 140 lb 1/30/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 60 Female 1/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage 1/7/2007 Male 251 lb 1/30/2007 Pharmacist United States
Primary
Secondary
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 1/31/2007 United Kingdom
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 2/2/2007 United Kingdom
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Death 1/1/2005 52 Female 2/5/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 10/1/2004 54 Female 140 lb 2/22/2007 United States
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 2/15/2007 United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 10/20/2006 81 Female 168 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 121 lb 2/28/2007 United Kingdom
Primary
Secondary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Urticaria 9/1/2006 28 Female 200 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Haemorrhage Other Serious 1 4/18/2007
Primary
Secondary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Other Serious 91 Female 5/29/2007 Other Health Professional United States
Primary
Secondary
Spinal Cord Ischaemia Hospitalization 1/10/2007 77 Female 157 lb 4/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/1/2004 54 Female 140 lb 6/2/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/8/2003 Male 243 lb 6/7/2007 Japan
Primary
Concomitant
Hepatitis Life Threatening 5/1/2007 75 Female 6/15/2007 Physician Brazil
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 4/1/2005 75 Female 6/14/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/8/2003 Male 243 lb 6/21/2007 Japan
Primary
Concomitant
Hepatitis Life Threatening 5/1/2007 75 Female 6/22/2007 Physician Brazil
Primary
Concomitant
Skin Necrosis Hospitalization 58 Male 6/21/2007 United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 49 Male 7/12/2007 United States
Primary
Secondary
Concomitant
Exercise Tolerance Decreased Hospitalization 7/4/2007 Female 119 lb 7/17/2007 Argentina
Primary
Concomitant
Subdural Haemorrhage Other Serious 77 Male 121 lb 7/23/2007 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 2/6/2007 60 Male 7/25/2007 Physician Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 5/26/2007 90 Male 189 lb 7/27/2007 Pharmacist United States
Primary
Secondary
Skin Necrosis Hospitalization 58 Male 8/1/2007 United Kingdom
Primary
Secondary
Intracranial Haematoma Required Intervention 1/29/2007 64 Female 212 lb 5/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/1/2004 Male 9/5/2007 United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Shortened Other Serious 8/1/2007 Male 306 lb 9/5/2007 Consumer United States
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/5/2007 United States
Primary
Concomitant
Tremor Hospitalization 5/25/2007 0 Female 5 lb 9/11/2007 Physician Japan
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/11/2007 United States
Primary
Concomitant
Tremor Hospitalization 5/25/2007 Male 7 lb 9/12/2007 Physician Japan
Primary
Concomitant
Somnambulism 35 Female 9/20/2007 Other Health Professional Canada
Primary
Concomitant
Heart Rate Increased Other Serious 10/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 72 Female 10/20/2007 Physician United Kingdom
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 11/2/2007 United States
Primary
Concomitant
Tenderness Hospitalization 3/5/2007 87 Male 170 lb 11/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 54 Male 11/22/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/7/2007 63 Male 165 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Life Threatening 11/14/2007 67 Male 11/26/2007 Pharmacist United States
Primary
Secondary
Laryngeal Oedema Life Threatening 11/17/2007 35 Female 12/4/2007 Physician Egypt
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Hospitalization 12/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 12/14/2007
Primary
Secondary
Transient Ischaemic Attack Death Female 12/14/2007
Primary
Secondary
Somnambulism 12/29/2006 35 Female 12/12/2007 Other Health Professional Canada
Primary
Concomitant
Ototoxicity Other Serious 9/7/2007 70 Male 167 lb 12/17/2007 Pharmacist United States
Primary
Concomitant
Skin Discolouration Required Intervention 60 Male 12/14/2007 Ireland
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Hospitalization 60 Male 12/15/2007 Physician Ireland
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/23/2007 8 Male 57 lb 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 4/27/2007 85 Female 150 lb 12/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Hospitalization 4/1/2007 75 Female 1/2/2008 Pharmacist United States
Primary
Secondary
Renal Cell Carcinoma Hospitalization 60 Male 12/18/2007 Ireland
Primary
Secondary
Fungal Sepsis Other Serious 1/1/2004 47 Female 1/21/2008 Physician Turkey
Primary
Concomitant
Thrombocytopenia Life Threatening 11/14/2007 67 Male 1/24/2008 Pharmacist United States
Primary
Secondary
Renal Cell Carcinoma Required Intervention 60 Male 1/23/2008 Ireland
Primary
Secondary
Upper Gastrointestinal Haemorrhage Death 8/1/2002 68 Male 201 lb 2/1/2008 United States
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 2/5/2008 United States
Primary
Concomitant
Dermatitis Exfoliative Generalised Hospitalization 1/8/2008 36 Female 157 lb 1/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Required Intervention 60 Male 2/5/2008 Ireland
Primary
Secondary
Vomiting Life Threatening 12/26/2007 74 Male 2/18/2008 Pharmacist United States
Primary
Secondary
Drug Interaction Other Serious 3/12/2008 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Blood Potassium Increased Required Intervention 1/13/2008 41 Male 331 lb 2/20/2008 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 3/21/2008 75 Female 128 lb 4/4/2008 Consumer United States
Primary
Secondary
Concomitant
Death Death 1/29/2007 Male 176 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 7/4/2007 Female 119 lb 4/28/2008 Argentina
Primary
Concomitant
Endocarditis Other Serious Female 155 lb 4/29/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Failure Other Serious 5/23/2008 Canada
Primary
Concomitant
Retroperitoneal Haematoma Life Threatening 57 Male 5/23/2008
Primary
Secondary
Concomitant
Ventricular Failure Other Serious 5/27/2008 Canada
Primary
Concomitant
Ventricular Failure Other Serious 5/30/2008 Canada
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 5/8/2008 78 Female 5/13/2008 Pharmacist United States
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 6/18/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/25/2008 66 Male 6/20/2008 Consumer Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 69 Female 6/26/2008 Other Health Professional Canada
Primary
Secondary
Haemorrhage Intracranial Death 6/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Subdural Haematoma Other Serious Female 6/26/2008 Italy
Primary
Secondary
Fatigue Hospitalization 4/25/2008 Male 6/28/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Death 1/14/1998 Female 7/7/2008 Physician Canada
Primary
Concomitant
Pain In Extremity Life Threatening 5/1/2008 55 Male 203 lb 7/3/2008 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/8/2007 61 Female 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 69 Female 7/4/2008 Canada
Primary
Secondary
Posturing Death 1/1/2006 53 Female 7/4/2008 Nepal
Primary
Secondary

Drug Data