Heparin Sodium combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Prothrombin Time Prolonged Required Intervention 12/7/2005 56 Male 97 lb 1/20/2006 Physician Japan
Primary
Concomitant
Dehydration Hospitalization 9/16/2005 61 Female 2/13/2006 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 3/29/2005 66 Female 278 lb 3/9/2006 Consumer Australia
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 2/28/2006 78 Female 3/21/2006 United States
Primary
Secondary
Hepatic Function Abnormal Death 4/5/2006 70 Male 4/21/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 20 Female 5/26/2006 Israel
Primary
Concomitant
Staphylococcal Infection Life Threatening 5/8/2006 69 Male 7/7/2006 Other Health Professional Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 75 Female 119 lb 7/27/2006 Physician Japan
Primary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 79 Female 323 lb 8/3/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 20 Female 8/9/2006 Physician Israel
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 4/5/2006 70 Male 8/30/2006 Physician Japan
Primary
Secondary
Concomitant
Hypoalbuminaemia Required Intervention 1/17/2006 40 Female 106 lb 9/20/2006 Physician Japan
Primary
Concomitant
Thrombophlebitis Other Serious 1/1/2005 51 Male 10/3/2006 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 5/1/2006 69 Male 9/29/2006 Japan
Primary
Concomitant
Prothrombin Time Required Intervention 12/7/2005 56 Male 97 lb 2/14/2007 Physician Japan
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Thrombosis Required Intervention 64 Male 5/17/2007 Physician United States
Primary
Concomitant
Splenic Vein Thrombosis Required Intervention 64 Male 5/17/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 78 Male 4/30/2007 Other Health Professional United States
Primary
Concomitant
Post Procedural Complication Hospitalization Male 116 lb 7/11/2007 Physician Japan
Primary
Concomitant
Mediastinitis Hospitalization 10/27/2006 Male 116 lb 8/10/2007 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 0 9/21/2007 Netherlands
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Male 175 lb 11/12/2007 Consumer United States
Primary
Secondary
Concomitant
Interacting
Visual Disturbance 12/26/2007 66 Female 126 lb 2/16/2008 United States
Primary
Concomitant
Vomiting 1/15/2008 46 Female 163 lb 2/16/2008 United States
Primary
Concomitant
Tachycardia 1/11/2008 32 Female 2/18/2008 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 76 Male 159 lb 2/21/2008 United States
Primary
Concomitant
Tachycardia 1/11/2008 32 Female 2/27/2008 Other Health Professional United States
Primary
Concomitant
Vomiting 1/15/2008 46 Female 163 lb 2/27/2008 United States
Primary
Concomitant
Visual Disturbance 12/26/2007 66 Female 126 lb 2/27/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/7/2008 74 Female 3/3/2008 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Disability 1/1/2007 60 Male 2/27/2008 Physician Ireland
Primary
Secondary
Pulmonary Embolism Life Threatening 2/7/2008 74 Female 3/5/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 7/1/2007 48 Male 194 lb 3/6/2008 Consumer United States
Primary
Concomitant
Thirst 2/7/2008 72 Male 300 lb 3/24/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/7/2008 74 Female 3/28/2008 Physician Japan
Primary
Secondary
Concomitant
Necrosis 5/1/2007 77 Female 209 lb 3/28/2008 Consumer United States
Primary
Concomitant
Thrombosis Death 2/22/2008 85 Female 3/27/2008 United States
Primary
Concomitant
Urticaria 2/1/2008 73 Female 117 lb 4/2/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/2/2008 30 Male 4/8/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Subcutaneous Abscess 2/1/2008 73 Female 117 lb 4/17/2008 Pharmacist United States
Primary
Concomitant
Injection Site Rash 9/19/2007 37 Female 160 lb 4/16/2008 Pharmacist United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 2/18/2008 68 Male 179 lb 5/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/2/2008 30 Male 5/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/26/2008 11 Male 68 lb 6/18/2008 Physician Japan
Primary
Secondary
Concomitant
Procedural Pain Life Threatening 55 Male 203 lb 7/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Life Threatening 8/6/2008 72 Male 195 lb 8/7/2008 Pharmacist United States
Primary
Concomitant
Ventricular Septal Defect Other Serious Female 8/12/2008 United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Required Intervention 8/6/2008 72 Male 195 lb 8/22/2008 Pharmacist United States
Primary
Concomitant
Small Intestine Carcinoma Other Serious 7/13/2007 82 Male 9/5/2008
Primary
Secondary
Concomitant
Urine Bilirubin Increased Hospitalization 4/28/2008 73 Female 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 8/7/2008 Male 121 lb 10/14/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 5/1/2007 28 Female 11/4/2008 Consumer United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 33 Female 11/6/2008 Other Health Professional Turkey
Primary
Secondary
Thrombosis Hospitalization 35 Female 11/14/2008 Other Health Professional United States
Primary
Secondary
Thrombosis Hospitalization 35 Female 11/20/2008 United States
Primary
Secondary
Thrombosis Hospitalization 35 Female 183 lb 12/11/2008 United States
Primary
Secondary
International Normalised Ratio Increased Other Serious 8/3/2007 82 Male 12/26/2008 Other Health Professional Japan
Primary
Secondary
Interacting
Skin Necrosis Hospitalization 64 Female 12/30/2008 Other Health Professional United States
Primary
Secondary
Skin Necrosis Hospitalization 64 Female 1/7/2009 Other Health Professional United States
Primary
Secondary
Intra-abdominal Haematoma Life Threatening 12/1/2008 71 Male 172 lb 1/26/2009 Pharmacist United States
Primary
Secondary
Thrombosis Other Serious 61 Male 1/30/2009 Pharmacist United States
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 64 Female 1/16/2009 Physician United States
Primary
Secondary
Shock Haemorrhagic Other Serious 33 Female 3/26/2009 Other Health Professional Turkey
Primary
Secondary
Pregnancy Other Serious 27 Female 4/1/2009 Other Health Professional India
Primary
Secondary
Unevaluable Event Hospitalization 10/1/2008 4/2/2009 Consumer United States
Primary
Concomitant
Pregnancy Other Serious 27 Female 4/16/2009 Other Health Professional India
Primary
Secondary
Hypotension Hospitalization 3/1/2009 64 Male 4/21/2009 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Hospitalization 10/1/2008 4/23/2009 Consumer United States
Primary
Concomitant
Renal Tubular Disorder Hospitalization 3/31/2009 Female 5/27/2009 Other Health Professional Japan
Primary
Concomitant
Vascular Access Complication Hospitalization 4/26/2009 82 Male 174 lb 6/2/2009 Pharmacist United States
Primary
Secondary
Heparin-induced Thrombocytopenia Other Serious 60 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Heparin-induced Thrombocytopenia Other Serious 60 Male 8/11/2009 Other Health Professional United States
Primary
Secondary
Thrombosis Required Intervention 69 Female 9/24/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/13/2007 82 Male 10/8/2009 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 67 Female 11/16/2009 Other Health Professional China
Primary
Secondary
Thrombocytopenia Other Serious 67 Female 11/23/2009 Other Health Professional China
Primary
Secondary
Venous Thrombosis Other Serious 23 Male 12/1/2009 Other Health Professional Czech Republic
Primary
Secondary
Aortic Dissection Rupture Death 2/17/2009 Male 119 lb 12/15/2009 Pharmacist Japan
Primary
Concomitant
Renal Failure Other Serious 68 Male 12/24/2009 Other Health Professional Japan
Primary
Secondary
International Normalised Ratio Increased Hospitalization 59 Male 1/5/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 59 Male 1/11/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Other Serious 9/25/2009 71 Female 2/5/2010 Physician Japan
Primary
Secondary
Hemianopia Homonymous Other Serious 73 Male 2/17/2010 Other Health Professional Australia
Primary
Secondary
Wound Dehiscence Other Serious 9/1/2006 31 Female 194 lb 2/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 68 Male 3/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/10/2009 Female 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 3/31/2009 Female 3/30/2010 Other Health Professional Japan
Primary
Concomitant
Urine Output Decreased Other Serious 10/1/2007 63 Male 193 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/18/2007 83 Male 5/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 41 Male 5/26/2010 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Life Threatening 41 Male 6/1/2010 Other Health Professional United States
Primary
Secondary
Wound Secretion Other Serious 9/1/2008 76 Female 6/15/2010 Lawyer United States
Primary
Concomitant
Paraesthesia Other Serious 12/1/2007 48 Female 174 lb 6/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 85 Female 126 lb 6/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 72 Female 6/17/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 6/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 12/29/2007 75 Male 6/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension 5/15/2008 35 Female 108 lb 6/23/2010 Lawyer United States
Primary
Concomitant
Drug Interaction Other Serious 3/27/2007 22 Female 202 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 10/2/2007 87 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 55 Male 183 lb 6/28/2010 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 5/21/2008 58 Female 198 lb 7/1/2010 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/9/2008 77 Female 7/1/2010 Lawyer United States
Primary
Concomitant
Respiratory Arrest Other Serious 1/1/2008 63 Male 7/8/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2007 48 Male 225 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2007 77 Male 7/8/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Fungal Other Serious 2/1/2008 79 Male 185 lb 7/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Hypertension Other Serious 6/1/2008 58 Male 280 lb 7/8/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2007 61 Male 7/15/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 1/9/2008 79 Female 7/15/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 8/25/2008 72 Male 7/15/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 12/30/2007 98 Male 7/15/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2008 73 Male 7/15/2010 Lawyer United States
Primary
Concomitant
Coronary Artery Disease Other Serious 12/10/2007 84 Male 7/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2007 74 Female 163 lb 7/19/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 3/1/2008 35 Female 478 lb 7/20/2010 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 3/1/2008 78 Female 7/20/2010 Lawyer United States
Primary
Concomitant
Pruritus Hospitalization 2/1/2008 59 Female 258 lb 7/20/2010 Lawyer United States
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 1/1/2008 51 Female 7/21/2010 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/22/2008 84 Female 7/21/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 40 Female 439 lb 7/21/2010 Lawyer United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 9/1/2007 77 Male 183 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 1/1/2008 63 Male 141 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 10/1/2007 69 Female 157 lb 7/22/2010 Lawyer United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 50 Male 328 lb 7/22/2010 Lawyer United States
Primary
Concomitant
Respiratory Failure Other Serious 12/8/2004 59 Female 7/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 11/1/2007 62 Female 207 lb 7/23/2010 Lawyer United States
Primary
Concomitant
Paraesthesia Other Serious 2/3/2010 24 Female 205 lb 7/23/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 2/16/2008 44 Male 7/27/2010 Lawyer United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 5/17/2009 72 Male 5/27/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Fungal Required Intervention 1/1/2008 78 Male 186 lb 7/23/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/1/2008 67 Male 192 lb 7/30/2010 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Death 6/17/2010 60 Male 7/30/2010 Pharmacist Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/25/2008 65 Male 7/30/2010 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/12/2010 48 Female 106 lb 8/4/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 11/1/2007 77 Female 123 lb 8/4/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/10/2009 50 Female 84 lb 8/10/2010 Physician Japan
Primary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 3/1/2008 75 Male 8/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haemothorax Other Serious 6/25/2010 78 Male 8/30/2010 Other Health Professional Japan
Primary
Concomitant
Porokeratosis Other Serious 63 Male 9/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Wound Dehiscence Other Serious 9/1/2006 31 Female 194 lb 9/16/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 48 Female 119 lb 9/30/2010 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 25 Female 10/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 66 Female 238 lb 10/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2010 75 Female 112 lb 10/27/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data