Heparin Sodium combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Prothrombin Time Prolonged Required Intervention 12/7/2005 56 Male 97 lb 1/20/2006 Physician Japan
Primary
Concomitant
Myoglobin Blood Increased Life Threatening 12/18/2005 44 Male 2/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Unknown 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chills Other Serious 10/18/2005 Male 128 lb 6/28/2006 Japan
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 50 Female 88 lb 7/20/2006 Physician India
Primary
Concomitant
Prothrombin Time Required Intervention 12/7/2005 56 Male 97 lb 2/14/2007 Physician Japan
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 9/30/2006 62 Female 141 lb 6/14/2007 Physician Germany
Primary
Concomitant
Post Procedural Complication Hospitalization Male 116 lb 7/11/2007 Physician Japan
Primary
Concomitant
Atrioventricular Block Complete Life Threatening 7/12/2007 Female 97 lb 7/24/2007 Physician Japan
Primary
Concomitant
Atrioventricular Block Complete Life Threatening 7/12/2007 Female 97 lb 8/2/2007 Physician Japan
Primary
Concomitant
Mediastinitis Hospitalization 10/27/2006 Male 116 lb 8/10/2007 Physician Japan
Primary
Concomitant
Nephritis Interstitial Hospitalization 7/13/2007 79 Female 186 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 3/22/2007 69 Male 111 lb 11/21/2007 Japan
Primary
Secondary
Concomitant
Vascular Occlusion Other Serious 45 Male 11/19/2007 Physician United States
Primary
Concomitant
Vascular Occlusion 3/19/2006 Male 12/5/2007 United States
Primary
Concomitant
Atrioventricular Block Complete Life Threatening 7/12/2007 Female 97 lb 12/7/2007 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 11/13/2007 41 Male 12/28/2007 Pharmacist Japan
Primary
Concomitant
Thermal Burn Hospitalization 10/31/2003 58 Male 2/1/2008 Physician Germany
Primary
Secondary
Concomitant
Thermal Burn Other Serious 10/31/2003 Male 2/22/2008 Physician Germany
Primary
Secondary
Thermal Burn Other Serious 10/31/2003 Male 3/12/2008 Physician Germany
Primary
Secondary
Thrombocytopenia Life Threatening 2/22/2008 61 Male 3/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Required Intervention 4/9/2008 75 Female 212 lb 4/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Hypertension Required Intervention 4/9/2008 75 Female 212 lb 5/2/2008 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/13/2008 31 Female 6/17/2008 Japan
Primary
Concomitant
Atrioventricular Block Complete Life Threatening 7/12/2007 Female 97 lb 7/15/2008 Physician Japan
Primary
Concomitant
Cardiac Arrest Death 54 Male 101 lb 7/21/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/13/2008 31 Female 7/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/13/2008 31 Female 8/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 77 Female 10/10/2008 United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 11/19/2007 76 Female 97 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 11/19/2007 76 Female 97 lb 12/18/2008 Physician Japan
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 8/18/2008 Female 111 lb 12/26/2008 Physician Japan
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 8/18/2008 Female 111 lb 12/29/2008 Physician Japan
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 8/18/2008 Female 111 lb 1/22/2009 Physician Japan
Primary
Concomitant
Heart Rate Increased Other Serious 8/18/2008 Female 111 lb 2/4/2009 Physician Japan
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2009 Male 157 lb 2/4/2009 Other Health Professional Germany
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2009 Male 157 lb 2/9/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Threatened Labour Hospitalization 6/22/2008 40 Female 2/6/2009 Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 1/27/2009 2/24/2009 Physician France
Primary
Concomitant
Toxic Encephalopathy Other Serious 1/27/2009 4/28/2009 Physician France
Primary
Concomitant
Toxic Encephalopathy Other Serious 1/30/2009 38 5/8/2009 France
Primary
Concomitant
No Adverse Event Death 73 7/6/2009 Other Health Professional Japan
Primary
Concomitant
Toxic Encephalopathy Other Serious 1/30/2009 38 7/7/2009 France
Primary
Concomitant
Neuromuscular Block Prolonged 8/22/2008 40 Female 7/23/2009 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 6/16/2009 88 8/31/2009 Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/2/2009 Physician Japan
Primary
Concomitant
No Adverse Event Death 73 9/4/2009 Other Health Professional Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/15/2009 Physician Japan
Primary
Concomitant
Hypertransaminasaemia Other Serious 4/6/2009 37 Male 10/29/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/1/2008 78 Male 137 lb 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 2/26/2010 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 2/4/2008 Male 3/16/2010 Physician Germany
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2008 78 Male 137 lb 4/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Dependence Hospitalization 36 5/20/2010 Physician United States
Primary
Secondary
Suicidal Ideation Hospitalization 36 5/20/2010 Physician United States
Primary
Secondary
Pulmonary Oedema Hospitalization 36 5/20/2010 Physician United States
Primary
Secondary
Sepsis Other Serious 7/14/2009 79 Female 6/1/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 36 Male 123 lb 6/11/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2008 45 Female 6/11/2010 Lawyer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2008 65 Male 258 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Tubulointerstitial Nephritis Required Intervention 23 Female 133 lb 6/15/2010 United States
Primary
Secondary
Concomitant
White Clot Syndrome Other Serious 3/1/2008 58 Male 174 lb 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Haematoma Other Serious 12/1/2007 57 Male 159 lb 6/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Wound Necrosis Other Serious 6/1/2008 33 Male 6/17/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 4/1/2008 31 Female 284 lb 6/18/2010 Lawyer United States
Primary
Concomitant
Sepsis Other Serious 1/1/2008 35 Male 157 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2008 68 Male 6/25/2010 Lawyer United States
Primary
Concomitant
White Clot Syndrome Other Serious Male 175 lb 6/29/2010 Lawyer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2007 58 Female 6/29/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 1/23/2008 78 Female 7/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/1/2007 53 Female 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/25/2008 72 Male 7/15/2010 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 12/1/2007 50 Male 309 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 1/21/2008 86 Male 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Other Serious 7/14/2008 34 Female 7/28/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 58 Female 8/2/2010 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/12/2010 48 Female 106 lb 8/4/2010 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 72 Male 8/5/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 4/28/2008 74 Male 190 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Vessel Puncture Site Haematoma Other Serious 3/1/2008 45 Female 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/14/2009 79 Female 8/10/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 7/14/2009 79 Female 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 10/11/2010 United States
Primary
Concomitant
Pneumonia Bacterial Other Serious 4/13/2010 59 Male 11/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Intestinal Ischaemia Death 5/23/2010 68 Male 12/10/2010 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Death 78 Male 11/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/4/2003 82 Male 12/23/2010 Other Health Professional United States
Primary
Secondary
Rhabdomyolysis Hospitalization 12/4/2003 82 Male 12/23/2010 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 12/23/2010 United States
Primary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/29/2010 11 Male 1/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 2/4/2008 59 Male 1/19/2011 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/29/2010 11 Male 70 lb 2/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haematemesis Hospitalization 11/10/2010 75 Male 148 lb 2/17/2011 Physician France
Primary
Concomitant
Coagulation Time Prolonged Death 5/23/2010 68 Male 2/28/2011 Other Health Professional Japan
Primary
Concomitant
Tongue Haematoma Hospitalization 61 Male 130 lb 2/23/2011 Physician Japan
Primary
Secondary
Concomitant
Prothrombin Level Abnormal Life Threatening 45 Female 2/17/2011 Pharmacist Canada
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 3/1/2001 40 Female 128 lb 3/4/2011 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/30/2010 11 Male 70 lb 3/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain Death 9/1/2005 66 Female 175 lb 3/18/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 7/1/2005 67 Male 250 lb 3/21/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 11/8/2006 60 Male 168 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Other Serious 7/1/2005 67 Male 250 lb 3/21/2011 Consumer United States
Primary
Concomitant
Hypoxia Life Threatening 2/14/2011 52 Female 3/28/2011 Physician France
Primary
Secondary
Concomitant
Pain Hospitalization 9/30/2005 82 Female 120 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 7/12/2006 64 Female 190 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Hospitalization 9/30/2005 82 Female 120 lb 3/29/2011 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 7/12/2006 64 Female 190 lb 3/29/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 7/25/2005 65 Male 213 lb 3/29/2011 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization Male 258 lb 3/30/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death Male 258 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 11/1/2006 79 Female 190 lb 3/30/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 1/6/2004 78 Male 165 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 11/4/2006 74 Male 165 lb 3/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Death 10/1/2007 75 Male 157 lb 3/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Unevaluable Event Death 1/1/2005 73 Male 180 lb 4/5/2011 Lawyer United States
Primary
Concomitant
Pain Death 9/7/1998 80 Male 174 lb 4/5/2011 Consumer United States
Primary
Concomitant
Stress Other Serious 9/7/1998 80 Male 174 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Emotional Distress Death 11/18/2005 80 Female 113 lb 4/6/2011 Lawyer United States
Primary
Concomitant
Rectal Haemorrhage Life Threatening 11/10/2010 75 Male 148 lb 4/13/2011 Physician France
Primary
Concomitant
Dysstasia Hospitalization 1/1/2010 69 Male 165 lb 4/12/2011 Physician Germany
Primary
Concomitant
Rectal Haemorrhage Life Threatening 11/10/2010 75 Male 148 lb 4/22/2011 Physician France
Primary
Concomitant
Agitation Death 1/1/2010 69 Male 165 lb 4/15/2011 Other Health Professional Germany
Primary
Concomitant
Haematemesis Death 11/10/2010 75 Male 148 lb 5/25/2011 Physician France
Primary
Concomitant
Proteinuria Hospitalization 1/25/2011 23 Female 5/25/2011 Other Health Professional France
Primary
Secondary
Oedema Other Serious 1/1/2007 65 Male 5/27/2011 Physician United States
Primary
Concomitant
Anhedonia Other Serious 5/17/2007 58 Male 150 lb 5/31/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Death 6/4/2008 74 Male 141 lb 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Pulse Absent Life Threatening 11/19/2007 76 Female 97 lb 9/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Death 8/31/2011 74 Female 124 lb 10/4/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/16/2011 67 Male 10/4/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Oliguria Death 6/4/2008 74 Male 141 lb 10/5/2011 Physician Japan
Primary
Secondary
Concomitant
Nikolsky's Sign Other Serious 8/15/2009 45 Male 176 lb 10/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Nikolsky's Sign Death 8/22/2009 45 Male 176 lb 10/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 6/24/2009 84 Female 86 lb 10/14/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/16/2011 67 Male 10/25/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Scab Death 8/15/2009 45 Male 176 lb 11/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/1/2010 70 Male 165 lb 12/8/2011 Physician Germany
Primary
Concomitant
Culture Wound Positive Hospitalization 9/24/2011 44 Female 99 lb 12/27/2011 Physician United States
Primary
Concomitant

Drug Data