Heparin combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stem Cell Transplant Life Threatening 12/16/2005 31 Male 1/3/2006 Other Health Professional Germany
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Atrial Flutter Life Threatening 1/10/2006 77 Female 142 lb 1/13/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Required Intervention 11/9/2005 79 Female 1/16/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 1/20/2006 Other Health Professional Germany
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Vomiting 6/28/2005 64 Female 148 lb 10/14/2005 United States
Primary
Concomitant
Troponin Increased Other Serious 1/1/2005 63 Female 1/27/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 7/24/2005 47 Male 190 lb 1/24/2006 Other Health Professional Germany
Primary
Concomitant
Troponin Increased Other Serious 1/1/2005 63 Female 1/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Hyperglycaemia Death 82 Male 2/9/2006 Canada
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 2/16/2006 Physician
Primary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 2/20/2006 Physician
Primary
Concomitant
Hyponatraemia Other Serious 38 Female 2/13/2006 Canada
Primary
Concomitant
Rhabdomyolysis Disability 1/4/2006 50 Male 220 lb 2/23/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 9/14/2005 83 Female 198 lb 11/28/2005 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 38 Female 2/24/2006 Canada
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 3/8/2006 Other Health Professional Germany
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/26/2006 59 Male 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 4/11/2006 Other Health Professional France
Primary
Concomitant
Sternal Fracture Other Serious 6/5/2005 57 Male 4/11/2006 Physician Netherlands
Primary
Secondary
Concomitant
Platelet Disorder Other Serious 2/6/2006 56 Male 251 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Medication Error 1/9/2006 Pharmacist United States
Primary
Secondary
Methaemoglobinaemia Life Threatening 6/20/2005 17 Female 117 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Hyponatraemia Other Serious 9/18/1999 38 Female 11 lb 4/20/2006 Canada
Primary
Concomitant
Hypoglycaemia Death 82 Male 4/24/2006 Canada
Primary
Secondary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Renal Failure Hospitalization 1/10/2006 63 Male 5/5/2006 United States
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 67 5/3/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Required Intervention 12/13/2005 53 Male 169 lb 3/1/2006 United States
Primary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/28/2006 51 Female 5/9/2006 Other Health Professional Argentina
Primary
Concomitant
Interacting
Respiratory Distress Life Threatening 2/10/2006 63 Female 161 lb 5/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Submaxillary Gland Enlargement Life Threatening 1/22/2006 Female 118 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 5/6/2006 54 Male 143 lb 5/31/2006 Physician United States
Primary
Concomitant
White Blood Cell Disorder Other Serious 1/16/2006 60 Female 6/8/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Unresponsive To Verbal Stimuli Hospitalization 2/22/2006 76 Female 5/31/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 10/16/2005 51 Male 6/5/2006 Physician Germany
Primary
Concomitant
Jaundice Cholestatic Other Serious 3/18/2005 58 Male 6/15/2006 Consumer Canada
Primary
Concomitant
Serotonin Syndrome Hospitalization 2/22/2006 76 Female 6/14/2006 Pharmacist Switzerland
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 6/30/2006 Physician
Primary
Concomitant
Toe Amputation Hospitalization 2/22/2006 76 Female 6/28/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 1/1/2006 Male 7/6/2006 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Required Intervention 5/23/2006 60 Male 234 lb 5/30/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Disability 5/12/2006 85 Female 112 lb 5/24/2006 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 2/22/2006 76 Female 6/30/2006 Switzerland
Primary
Secondary
Concomitant
Myoclonus Hospitalization 4/23/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 10/16/2005 51 Male 7/21/2006 Physician Greece
Primary
Concomitant
Ruptured Cerebral Aneurysm Hospitalization 6/22/2006 45 Female 7/24/2006 France
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 7/14/2005 29 Male 8/1/2006 Consumer United States
Primary
Concomitant
Rash Pustular Hospitalization 6/22/2006 45 Female 8/4/2006 Physician France
Primary
Secondary
Concomitant
Postoperative Renal Failure Other Serious 67 Female 139 lb 7/28/2006 Physician Canada
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 6/22/2006 45 Female 7/31/2006 France
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 6/19/2006 45 Female 8/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pruritus 8/9/2006 41 Male 157 lb 8/17/2006 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 67 Unknown 8/14/2006 Denmark
Primary
Concomitant
Rash Pustular Hospitalization 6/19/2006 45 Female 8/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Uterine Leiomyoma Death 6/1/2006 78 Female 165 lb 8/16/2006 Bulgaria
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Rash Pustular Hospitalization 6/22/2006 45 Female 10/9/2006 Physician France
Primary
Secondary
Concomitant
Shock Haemorrhagic Death 5/23/2006 Male 2 lb 10/10/2006 Physician Japan
Primary
Concomitant
Wound Other Serious 2/1/2006 Female 176 lb 10/10/2006 Physician Poland
Primary
Concomitant
Panic Attack Hospitalization 9/3/2006 63 Male 258 lb 10/5/2006 Germany
Primary
Concomitant
Rhabdomyolysis Required Intervention 8/31/2006 65 Male 189 lb 9/27/2006 Pharmacist United States
Primary
Concomitant
Uterine Leiomyoma Death 6/1/2006 78 Female 165 lb 10/11/2006 United States
Primary
Secondary
Concomitant
Procedural Hypotension Required Intervention 8/10/2006 73 Female 117 lb 10/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 80 Male 10/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Haematocrit Decreased Other Serious 10/20/2006 Male 217 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Cerebral Haemorrhage Death 10/29/2006 56 Female 154 lb 10/29/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Death 5/2/2006 64 Female 165 lb 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 11/6/2006 Physician
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/6/2006
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/6/2006
Primary
Concomitant
Lung Disorder Other Serious 11/6/2006
Primary
Concomitant
Lymphadenopathy Other Serious 6/1/2006 44 Male 11/7/2006 Physician France
Primary
Secondary
Concomitant
Uterine Leiomyoma Death 6/1/2006 78 Female 165 lb 10/31/2006 United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 9/7/2006 67 Male 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 9/7/2006 67 Male 11/3/2006 United Kingdom
Primary
Concomitant
Kaposi's Sarcoma Other Serious 6/1/2006 44 Male 11/17/2006 Physician France
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 9/7/2006 67 Male 11/9/2006 United Kingdom
Primary
Concomitant
Haematoma Life Threatening 10/23/2006 71 Female 11/9/2006 Italy
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 11/1/2006 44 Male 11/13/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Life Threatening 10/26/2005 75 Female 105 lb 11/20/2006 Pharmacist United States
Primary
Concomitant
Wound Other Serious 2/1/2006 Female 176 lb 11/29/2006 Physician Poland
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Vomiting Life Threatening 9/23/2006 Male 240 lb 11/29/2006 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 11/27/2006 France
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/20/2006 35 Male 176 lb 12/11/2006 Physician Canada
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 9/23/2006 Male 240 lb 12/14/2006 Physician Canada
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 9/23/2006 Male 240 lb 1/4/2007 Physician Canada
Primary
Concomitant
Ventricular Fibrillation Other Serious 70 Male 12/29/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/6/2006 58 Male 212 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Cardiac Failure Death 10/18/2005 65 Male 121 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Cardiac Failure Death 10/14/2005 65 Male 121 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Required Intervention 7/12/2006 40 Female 7/16/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Systemic Mycosis Death 11/22/2006 3 Female 33 lb 1/2/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/24/2006 70 Female 1/11/2007 Consumer France
Primary
Secondary
Concomitant
Haemorrhage Required Intervention 8/16/2006 78 Female 150 lb 10/2/2006 United States
Primary
Concomitant
Subclavian Vein Thrombosis Life Threatening 10/17/2006 43 Female 155 lb 10/22/2006 United States
Primary
Concomitant
Hypotension Required Intervention 7/30/2004 49 Male 3/6/2006 United States
Primary
Secondary
Concomitant
Surgical Procedure Repeated Other Serious 1/5/2007 83 Female 1/19/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Linear Iga Disease Death 9/1/2005 83 Male 187 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 7/1/2006 73 Male 165 lb 1/26/2007 Physician France
Primary
Concomitant
Human Herpesvirus 8 Infection Other Serious 6/1/2006 44 Male 2/1/2007 Physician France
Primary
Secondary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 4/23/2006 53 Male 2/1/2007 Physician France
Primary
Secondary
Concomitant
Klebsiella Infection Hospitalization 12/14/2006 53 Male 2/2/2007 Physician France
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/5/2007 83 Female 1/30/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Human Herpesvirus 8 Infection Other Serious 6/1/2006 44 Male 2/5/2007 Physician France
Primary
Secondary
Concomitant
Human Herpesvirus 8 Infection Other Serious 6/1/2006 44 Male 2/5/2007 Physician France
Primary
Secondary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
Hypotension Hospitalization 10/19/2006 60 Male 2/9/2007 Pharmacist United States
Primary
Concomitant
Shock Life Threatening 12/17/2005 24 Male 2/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 2/9/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 2/15/2007 Other Health Professional France
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Renal Failure Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Cardiovascular Insufficiency Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Respiratory Failure Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Shock Life Threatening 12/17/2005 24 Male 3/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 10/20/2005 34 Male 4/3/2007 Physician France
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 11/6/2006 54 Female 265 lb 11/8/2006 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 4/3/2007 59 Female 187 lb 4/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Superior Vena Caval Occlusion Life Threatening 3/1/2007 Male 7 lb 4/13/2007 Physician United States
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 9/23/2006 Male 196 lb 4/16/2007 Physician Canada
Primary
Concomitant
Myocardial Rupture Other Serious 2/22/2007 70 Male 176 lb 4/17/2007
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Cardiovascular Insufficiency Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Respiratory Failure Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Encephalitis Life Threatening 1/17/2007 43 Male 220 lb 4/27/2007 Other Health Professional Germany
Primary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant

Drug Data