Heparin combined with Metronidazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Embolism Other Serious 42 Male 1/10/2006 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/18/2004 33 209 lb 9/16/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Ventricular Failure Required Intervention 11/14/2005 74 Male 229 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased 11/25/2005 Male 326 lb United States
Primary
Concomitant
Hyperglycaemia Death 82 Male 2/9/2006 Canada
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 12/14/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 1/17/2006 34 Female 110 lb 2/8/2006 Physician United Kingdom
Primary
Concomitant
Therapy Non-responder Death 3/14/2006 68 Female 143 lb 3/21/2006 Physician Belgium
Primary
Concomitant
Therapy Non-responder Death 3/14/2006 68 Female 143 lb 3/27/2006 Physician Belgium
Primary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Death 82 Male 4/24/2006 Canada
Primary
Secondary
Concomitant
Septic Shock Death 3/14/2006 68 Female 143 lb 4/28/2006 Physician Belgium
Primary
Concomitant
Vasospasm Required Intervention 4/17/2006 45 Female 168 lb 6/6/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/3/2006 73 Male 205 lb 2/23/2006 Other Health Professional United States
Primary
Concomitant
Renal Impairment Life Threatening 1/28/2006 44 Male 143 lb 2/7/2006 Pharmacist United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 70 Male 124 lb 1/26/2006 United States
Primary
Concomitant
Pancreatitis Hospitalization 5/12/2006 35 Male 7/6/2006 Other Health Professional France
Primary
Secondary
Respiratory Depression Life Threatening 2/25/2005 44 Female 7/24/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Required Intervention 4/17/2006 45 Female 168 lb 7/27/2006 Physician United States
Primary
Concomitant
Tachycardia Other Serious 5/12/2006 35 Male 8/15/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vena Cava Thrombosis Death 46 Female 110 lb 9/5/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Rash Other Serious 6/18/2006 87 Male 210 lb 8/29/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 6/3/2006 54 Female 130 lb 6/23/2006 Pharmacist United States
Primary
Concomitant
Spinal Cord Oedema Required Intervention 1/26/2006 58 Male 174 lb 5/2/2006 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 8/31/2006 65 Male 189 lb 9/27/2006 Pharmacist United States
Primary
Concomitant
Tumour Haemorrhage Life Threatening 9/18/2006 69 Male 198 lb 10/16/2006 Physician Germany
Primary
Concomitant
Tumour Haemorrhage Life Threatening 9/18/2006 69 Male 198 lb 10/19/2006 Physician Germany
Primary
Concomitant
Renal Failure Life Threatening 9/18/2006 69 Male 198 lb 10/23/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/18/2006 69 Male 198 lb 10/27/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/18/2006 69 Male 198 lb 11/1/2006 Physician Germany
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/3/2006 Physician Germany
Primary
Concomitant
Rash Other Serious 5/29/2006 48 Male 11/8/2006 Pharmacist Canada
Primary
Concomitant
Pyrexia Other Serious 5/18/2006 78 Female 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/15/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/27/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 12/4/2006 Physician Germany
Primary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 1/12/2007 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious 8/13/2006 56 Female 148 lb 1/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 1/31/2007 United Kingdom
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 2/2/2007 United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Required Intervention 4/17/2006 45 Female 168 lb 2/6/2007 Physician United States
Primary
Concomitant
Skin Lesion Other Serious 0 Male 2/15/2007 Other Health Professional Turkey
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 2/15/2007 United Kingdom
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 3/13/2007 Physician Germany
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 31 Male 1/18/2007 Physician United States
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 2/23/2004 41 Female 4/9/2007 Physician Sweden
Primary
Secondary
Concomitant
Shock Death 3/14/2006 Female 143 lb 4/13/2007 Belgium
Primary
Concomitant
Rash Pruritic Other Serious 11/16/2006 82 Male 113 lb 1/23/2007 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 4/1/2007 5/1/2007 Pharmacist United States
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/1/2007 Physician Germany
Primary
Concomitant
Loss Of Consciousness Required Intervention 4/11/2007 35 Male 240 lb 4/24/2007 Other Health Professional United States
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 2/23/2004 41 Female 5/11/2007 Physician Sweden
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/11/2007 Physician Germany
Primary
Concomitant
Septic Shock Life Threatening 9/1/2006 69 Male 198 lb 5/22/2007 Physician Germany
Primary
Concomitant
Neonatal Disorder Other Serious 4/20/2007 0 Female 1 lb 5/21/2007 Physician Germany
Primary
Concomitant
Patent Ductus Arteriosus Other Serious 4/20/2007 0 Female 1 lb 5/29/2007 Physician Germany
Primary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 11/25/2006 33 Female 6/6/2007 Pharmacist United States
Primary
Concomitant
Patent Ductus Arteriosus Other Serious 4/20/2007 0 Female 1 lb 6/21/2007 Physician Germany
Primary
Concomitant
Skin Haemorrhage Life Threatening 12/15/2006 69 Male 7/16/2007 Other Health Professional Denmark
Primary
Concomitant
Haemorrhage Required Intervention 7/8/2007 59 Male 209 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Skin Haemorrhage Life Threatening 12/15/2006 Male 7/23/2007 Other Health Professional Denmark
Primary
Concomitant
Surgery Other Serious 6/4/2007 50 Male 159 lb 8/4/2007 Physician Germany
Primary
Secondary
Surgery Other Serious 6/4/2007 50 Male 159 lb 8/8/2007 Physician Germany
Primary
Secondary
White Blood Cell Count Increased Other Serious 10/1/2003 60 Male 428 lb 8/9/2007 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 6/27/2007 Male 146 lb 8/14/2007 Italy
Primary
Concomitant
Urine Output Decreased Other Serious 6/4/2007 50 Male 159 lb 8/18/2007 Physician Germany
Primary
Secondary
Respiratory Rate Increased Required Intervention 6/1/2007 48 Female 6/8/2007 United States
Primary
Secondary
Concomitant
Death Hospitalization 9/1/2007 82 Female 154 lb 9/17/2007 Consumer United States
Primary
Concomitant
Rheumatoid Lung Hospitalization 8/1/2007 82 Female 154 lb 10/4/2007 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/1/2007 65 Female 302 lb 11/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Hospitalization 1/1/2007 Male 218 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Transfusion Reaction Hospitalization 10/8/2007 65 Female 302 lb 11/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Pyrexia Other Serious 15 Female 11/30/2007 Other Health Professional United States
Primary
Secondary
Ventricular Tachycardia Death 10/15/2007 76 Male 183 lb 10/16/2007 Pharmacist United States
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 15 Female 12/7/2007
Primary
Secondary
Concomitant
Petechiae Required Intervention 3/24/2008 85 Female 137 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/22/2008 82 Female 172 lb 5/2/2008 United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 4/15/2008 54 Male 5/5/2008 Pharmacist United States
Primary
Concomitant
Tendonitis Other Serious 8/5/2008 Female 145 lb 8/12/2008 Consumer United States
Primary
Concomitant
Tendonitis Other Serious 8/5/2008 Female 145 lb 8/12/2008 Consumer United States
Primary
Concomitant
Disseminated Tuberculosis Other Serious 6/1/2008 41 Female 8/28/2008 Physician Slovenia
Primary
Concomitant
Large Intestinal Ulcer Haemorrhage Life Threatening 5/28/2008 59 Male 9/9/2008 United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 8/13/2008 69 Female 9/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 2/23/2008 Male 10/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 1/1/2005 44 Female 10/22/2008 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/2008 59 Female 10/31/2008 Physician United States
Primary
Concomitant
Blood Potassium Increased Life Threatening 6/24/2008 Male 167 lb 7/2/2008 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 10/1/2008 44 Female 10/24/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Required Intervention 8/18/2008 48 Male 243 lb 10/1/2008 United States
Primary
Concomitant
Platelet Count Increased Required Intervention 8/30/2008 66 Female 287 lb 10/3/2008 Pharmacist United States
Primary
Concomitant
Septic Shock Hospitalization 11/18/2008 53 Male 12/17/2008 Other Health Professional United States
Primary
Concomitant
Tendonitis Other Serious 8/5/2008 Female 145 lb 12/19/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/13/2008 Male 1/16/2009 Pharmacist United States
Primary
Concomitant
Vessel Puncture Site Haematoma Other Serious 6/16/2008 Male 1/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 59 Female 1/21/2009 Physician United States
Primary
Concomitant
Vessel Puncture Site Haematoma Other Serious 6/16/2008 Male 1/21/2009 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Convulsion 2/8/2009 Female 2/12/2009 Pharmacist United States
Primary
Concomitant
Pancreatitis Required Intervention 2/1/2009 57 Female 163 lb 3/2/2009 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 25 Female 5/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 5/29/2009 Other Health Professional United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 Female 196 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 8/4/2004 Male 132 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/12/2004 Female 125 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Unevaluable Event Life Threatening Female 150 lb 6/24/2009 Pharmacist United States
Primary
Concomitant
Postoperative Thrombosis Required Intervention 4/7/2009 47 Male 218 lb 4/10/2009 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 5/6/2009 33 Male 207 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 26 7/9/2009 Other Health Professional India
Primary
Concomitant
No Adverse Event Other Serious 8/4/2004 65 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 7/5/2009 71 Female 175 lb 7/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 26 Female 7/20/2009
Primary
Secondary
Concomitant
Ureteric Stenosis Required Intervention 7/10/2003 69 Male 8/13/2009 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2009 Male 8/31/2009 Netherlands
Primary
Concomitant
Vitamin D Deficiency Death 80 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 9/16/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Required Intervention 6/21/2009 55 Male 202 lb 7/14/2009 Pharmacist United States
Primary
Concomitant
Lethargy Required Intervention 7/10/2009 85 Female 168 lb 7/10/2009 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 11/4/2008 68 Female 254 lb 11/12/2008 Pharmacist United States
Primary
Concomitant
Retching Required Intervention 6/12/2009 19 Male 159 lb 6/23/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 3/25/2009 Female 9/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 7/7/2009 Female 9/29/2009 Switzerland
Primary
Concomitant
Urinary Tract Infection Hospitalization 76 Female 9/25/2009 United States
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 3/25/2009 Female 10/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 3/25/2009 Female 10/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 7/7/2009 Female 10/22/2009 Switzerland
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/1/2004 Male 205 lb 10/28/2009 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Required Intervention 8/29/2009 53 Female 115 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Life Threatening 8/31/2009 59 Male 320 lb 9/1/2009 Pharmacist United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 9/23/2009 58 Female 115 lb 9/24/2009 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 8/1/2009 36 Female 183 lb 9/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 4/20/2006 61 Female 121 lb 11/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Stomatitis Other Serious 11/28/2009 17 Female 151 lb 12/15/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2003 Female 137 lb 3/1/2010 United States
Primary
Concomitant
Tracheal Ulcer Death 1/1/2009 Male 165 lb 3/2/2010 Physician Germany
Primary
Secondary
Concomitant

Drug Data