Heparin combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Retention Hospitalization 3/9/2005 65 Male 137 lb 1/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure Chronic Required Intervention 11/9/2005 79 Female 1/16/2006 Physician United States
Primary
Concomitant
Skin Discolouration Required Intervention 8/23/2005 Female 9/2/2005 United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Psychotic Disorder Required Intervention 10/9/2005 63 Male 154 lb 11/7/2005 Pharmacist United States
Primary
Concomitant
Haematuria Life Threatening 11/16/2005 88 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Varices Oesophageal Life Threatening 7/25/2005 60 Male 216 lb 2/2/2006 Physician Bulgaria
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 12/16/2005 52 Male 2/7/2006 Pharmacist United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 1/24/2006 66 Male 317 lb 2/9/2006 Pharmacist United States
Primary
Concomitant
Procedural Hypotension Required Intervention 11/8/2005 90 Male 198 lb 1/31/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Hyperglycaemia Death 82 Male 2/9/2006 Canada
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Eosinophilia Hospitalization 11/17/2005 Male 2/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 11/13/2005 74 Male 12/8/2005 Pharmacist United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 12/14/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Rash Hospitalization 7/19/2005 Male 271 lb 3/6/2006 Physician New Zealand
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 3/8/2006 Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/19/2005 93 Male 3/16/2006 Physician Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/29/2005 49 Male 170 lb 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 31 Male 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Hospitalization 12/12/2005 39 Female 170 lb 1/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Dystonia 2/20/2006 54 Male 3/14/2006 United Kingdom
Primary
Concomitant
Hallucination Other Serious 62 Female 3/31/2006 Pharmacist United States
Primary
Concomitant
Urinary Retention Hospitalization 3/9/2005 65 Male 137 lb 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 8/13/2001 76 Female 260 lb 4/14/2006 Physician United States
Primary
Concomitant
Hallucination Other Serious 62 Female 4/14/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2002 52 Male 185 lb 4/21/2006 Physician United States
Primary
Concomitant
Platelet Disorder Other Serious 2/6/2006 56 Male 251 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Death 82 Male 4/24/2006 Canada
Primary
Secondary
Concomitant
Wheezing Other Serious 3/15/2006 66 Female 133 lb 4/12/2006 Physician United States
Primary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Submaxillary Gland Enlargement Life Threatening 1/22/2006 Female 118 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/2/2006 66 198 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Required Intervention 2/2/2005 74 Male 319 lb 5/24/2006 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 5/11/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 11/19/2005 49 Male 203 lb 7/21/2006 Canada
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 8/11/2006 63 Female 8/17/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 47 Male 198 lb 8/29/2006 Romania
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 7/25/2006 52 Male 198 lb 8/29/2006 Romania
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/3/2006 56 Male 220 lb 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Haematuria Hospitalization 7/18/2006 67 Male 9/14/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Death 8/10/2006 77 Male 9/22/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cardiac Tamponade Life Threatening 11/7/2005 Male 181 lb 9/23/2006 Physician Australia
Primary
Concomitant
Occult Blood Positive Required Intervention 1/14/2006 74 Female 109 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/27/2006 83 Female 10/16/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Life Threatening 9/18/2006 69 Male 198 lb 10/23/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/27/2006 Physician Germany
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/9/2005 Female 190 lb 11/29/2006 Physician United States
Primary
Concomitant
Pericardial Haemorrhage Life Threatening 11/7/2005 Male 181 lb 11/29/2006 Physician Australia
Primary
Concomitant
Pneumonia Other Serious 10/20/2006 Male 137 lb 2/8/2007 Physician Canada
Primary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 9/8/2007 77 Female 165 lb 10/2/2007 United States
Primary
Concomitant
Renal Failure Hospitalization 10/15/2007 79 Male 172 lb 10/16/2007 Other Health Professional United States
Primary
Concomitant
Multiple Myeloma Hospitalization 5/4/2006 67 Male 172 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Arteriovenous Fistula Hospitalization 12/7/2006 Male 234 lb 11/2/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/27/2007 80 Female 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Transfusion Reaction Hospitalization 10/8/2007 65 Female 302 lb 11/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Skin Disorder Other Serious 45 Male 11/15/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Disability 8/5/2007 68 Female 234 lb 12/4/2007 Pharmacist United States
Primary
Concomitant
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 4/6/2007 61 Male 4/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 9/3/2007 6/12/2008 Consumer Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/4/2005 Male 6/13/2008 Pharmacist
Primary
Secondary
Concomitant
Toxic Encephalopathy Life Threatening 5/18/2008 92 Male 171 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Speech Disorder Other Serious 6/4/2008 Male 190 lb 6/16/2008 Consumer United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/22/2008 82 Female 172 lb 5/2/2008 United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 4/15/2008 54 Male 5/5/2008 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 9/12/2007 Male 100 lb 6/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 50 Male 196 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/1/2008 84 Male 209 lb 8/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 78 Male 134 lb 8/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 2/1/2002 8/5/2008 United States
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Life Threatening 57 Male 1/2/2009 Germany
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2008 73 Male 155 lb 1/5/2009 Physician Germany
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Feeling Hot Hospitalization 1/27/2009 51 Female 243 lb 2/17/2009 Pharmacist Australia
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Arteriovenous Fistula Site Haemorrhage Hospitalization 3/9/2009 72 Female 125 lb 3/24/2009 Pharmacist United States
Primary
Concomitant
Renal Transplant Hospitalization 10/27/2008 Male 131 lb 4/7/2009 Consumer United States
Primary
Concomitant
Thinking Abnormal Hospitalization 2/18/2009 Female 4/2/2009 Consumer United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 12/18/2007 Female 153 lb 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 3/24/2009 49 Male 278 lb 3/30/2009 Pharmacist United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 2/6/2009 77 Male 196 lb 3/18/2009 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 3/7/2009 81 Male 161 lb 3/10/2009 Pharmacist United States
Primary
Concomitant
Lethargy Required Intervention 2/17/2009 45 Female 138 lb 2/17/2009 Pharmacist United States
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 1/19/2009 25 Female 94 lb 2/3/2009 Pharmacist United States
Primary
Concomitant
Wheezing 5/4/2009 Male 5/8/2009 Pharmacist
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 5/1/2007 67 Male 165 lb 5/11/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 4/26/2009 51 Male 271 lb 5/5/2009 Pharmacist United States
Primary
Concomitant
Yellow Skin Other Serious 6/21/2006 66 Male 165 lb 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Meningitis Hospitalization 5/20/2006 53 Female 5/19/2009 United States
Primary
Concomitant
Syncope Hospitalization 2/23/2009 45 Male 5/21/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 5/29/2009 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 8/3/2008 62 Male 6/5/2009 Physician United States
Primary
Concomitant
Cerebral Haemorrhage Required Intervention 4/13/2009 Male 193 lb 4/14/2009 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/24/2009 89 Female 151 lb 4/27/2009 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 3/30/2009 66 Male 198 lb 5/4/2009 Pharmacist United States
Primary
Concomitant
Haemorrhagic Stroke Life Threatening 4/2/2009 Female 105 lb 4/11/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 5/18/2009 63 Male 181 lb United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/18/2009 56 Male 207 lb 8/12/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/14/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/17/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/20/2009 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/10/2009 66 Female 8/21/2009
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/10/2006 66 Female 8/24/2009
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Life Threatening 7/19/2009 Male 208 lb 9/8/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/8/2009 56 Female 150 lb 9/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 7/18/2009 56 Male 207 lb 9/10/2009 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 9/16/2009 Other Health Professional United States
Primary
Concomitant
Traumatic Lung Injury Death 70 Male 9/10/2009 United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2002 9/28/2009 United States
Primary
Secondary
Concomitant
Creatinine Renal Clearance Decreased Life Threatening 5/24/2009 50 Male 146 lb 6/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 5/15/2009 76 Female 192 lb 5/29/2009 Pharmacist United States
Primary
Concomitant
Oesophagitis Required Intervention 5/21/2009 63 Male 181 lb 6/24/2009 Pharmacist United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 5/29/2009 75 Male 146 lb 6/1/2009 Pharmacist United States
Primary
Concomitant
Paraesthesia Oral Hospitalization 11/11/2008 54 11/12/2008 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 76 Female 9/25/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/20/2004 50 Male 159 lb 9/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/18/2009 79 Female 139 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 7/19/2009 Male 208 lb 10/12/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/29/2009 Male 120 lb 10/16/2009 Physician United States
Primary
Concomitant
Hypotension Other Serious 10/4/2009 Male 10/16/2009 Physician United States
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 92 Male 10/23/2009 Pharmacist United States
Primary
Concomitant
Traumatic Lung Injury Hospitalization 70 Male 10/20/2009 United States
Primary
Concomitant
Mental Status Changes Required Intervention 8/29/2009 53 Female 115 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/30/2009 Male 187 lb 9/11/2009 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Life Threatening 9/23/2009 75 Male 209 lb 9/25/2009 Pharmacist United States
Primary
Concomitant
Hypotension Other Serious 10/4/2009 71 Male 10/29/2009 Physician United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 9/27/2009 44 Male 148 lb 10/2/2009 United States
Primary
Concomitant
Product Quality Issue Other Serious 9/27/2009 52 Male 201 lb 10/7/2009 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/18/2009 79 Female 139 lb 11/9/2009 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/4/2009 Male 11/10/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/8/2009 58 Male 165 lb 11/12/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 Female 162 lb 11/16/2009 Physician Australia
Primary
Concomitant
Cerebrovascular Accident Death 11/16/2009 67 Female 140 lb 11/25/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Female 11/18/2009 United States
Primary
Concomitant

Drug Data