Heparin combined with Melphalan Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tonic Convulsion Other Serious 50 Female 10/2/2009 Italy
Primary
Concomitant
Tumour Flare Hospitalization 8/6/2009 Female 127 lb 11/6/2009 Canada
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/14/2007 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 4/16/2009 Male 3/25/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Hesitation Other Serious 1/14/2007 Male 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/16/2008 73 Male 117 lb 3/24/2010 Physician Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 1/20/2010 70 Male 4/8/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2007 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 6/21/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1 Female 9/30/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 7 Female 9/30/2010 Physician Japan
Primary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Leukaemia Recurrent Other Serious 3 Female 10/12/2010 Physician United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2007 10/20/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 79 Female 11/2/2010 United States
Primary
Concomitant
Musculoskeletal Disorder Other Serious 83 Female 11/2/2010 United States
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1 Female 2/7/2011 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 7 Female 2/7/2011 Physician Japan
Primary
Concomitant
Hypoaesthesia Other Serious 7/2/2003 55 Male 187 lb 3/17/2011 United States
Primary
Secondary
Concomitant
Retinal Artery Embolism Other Serious 2 4/1/2011 Physician Switzerland
Primary
Concomitant
Retinal Detachment Other Serious 1 4/1/2011 Physician Switzerland
Primary
Concomitant
Retinal Artery Embolism Other Serious 2 4/1/2011 Physician Switzerland
Primary
Concomitant
Electrocardiogram T Wave Abnormal Other Serious 3/17/2009 66 Female 273 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2000 76 Female 201 lb 5/17/2011 Lawyer United States
Primary
Concomitant
Nervousness Other Serious 48 Female 250 lb 5/20/2011 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 3 5/24/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 3 5/24/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2 5/24/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1 5/24/2011 Other Health Professional United States
Primary
Concomitant
Retinopathy Other Serious 7 5/24/2011 Other Health Professional United States
Primary
Concomitant
Myositis Other Serious 7 5/18/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1 5/18/2011 Physician United States
Primary
Concomitant
Neoplasm Progression Other Serious 3 5/18/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Disability 2 6/2/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Disability 2 6/2/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Disability 3 6/2/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 5 6/2/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Disability 2 6/2/2011 Other Health Professional United States
Primary
Concomitant
Retinal Ischaemia Other Serious Female 6/2/2011 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Facial Other Serious 6/6/2011 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious Male 6/6/2011 Other Health Professional Spain
Primary
Secondary
Vitreous Haemorrhage Other Serious 5 5/27/2011 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Disability 2 5/27/2011 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 3 5/27/2011 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Disability 2 5/27/2011 Physician United States
Primary
Concomitant
Nausea Hospitalization 11/25/2010 72 Female 6/8/2011 Consumer Germany
Primary
Secondary
Concomitant
Retinal Exudates Other Serious Female 5/31/2011 Physician United States
Primary
Concomitant
Anaemia Other Serious 4/1/2008 54 Male 6/15/2011 Other Health Professional Spain
Primary
Secondary
Dermatitis Contact Other Serious 7/1/2002 59 Female 142 lb 6/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Constipation Hospitalization 2/1/2006 85 Male 7/29/2011 Other Health Professional United States
Primary
Concomitant
Metastatic Neoplasm Death 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Neoplasm Death 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Neoplasm Death 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Neoplasm Death 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neoplasm Progression Death 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Skin Cancer Death 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Neoplasm Progression Death 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Skin Cancer Death 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 2/3/2010 6 Male 35 lb 9/19/2011 Physician Japan
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Death 11/17/2009 6 Male 33 lb 9/19/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/19/2009 10 Male 49 lb 9/19/2011 Physician Japan
Primary
Concomitant
Deep Vein Thrombosis Other Serious 75 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cellulitis Other Serious 66 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 76 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Compartment Syndrome Other Serious 59 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cellulitis Other Serious 87 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cellulitis Other Serious 61 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cellulitis Other Serious 61 Female 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 75 Female 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cellulitis Other Serious 87 Female 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Compartment Syndrome Other Serious 59 Female 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Systemic Leakage Other Serious 76 Female 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cellulitis Other Serious 66 Female 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anticoagulation Drug Level Above Therapeutic Other Serious 67 Male 110 lb 10/20/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Hypoacusis Other Serious 2/1/2006 85 Male 11/15/2011 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Retinal Pigment Epitheliopathy Other Serious 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Retinal Pigment Epitheliopathy Other Serious 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Arterial Stenosis Other Serious 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Retinal Pigment Epitheliopathy Other Serious 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Retinal Detachment Other Serious 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Death 6/24/2010 29 Female 99 lb 12/8/2011 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Death 2/1/2011 74 Female 12/13/2011 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 2/4/2011 13 Female 86 lb 12/30/2011 Physician Japan
Primary
Concomitant
Haemolytic Anaemia Life Threatening 11/17/2009 6 Male 33 lb 12/30/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 3/11/2009 9 Male 49 lb 12/30/2011 Physician Japan
Primary
Concomitant
Infection Other Serious Female 1/1/2012 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 9/1/2003 46 Male 130 lb 1/2/2012 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious Female 1/3/2012 Physician United States
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Other Serious 9/1/2003 46 Male 130 lb 2/1/2012 Lawyer United States
Primary
Secondary
Concomitant
Enterococcal Bacteraemia Hospitalization 12/1/2011 65 Female 260 lb 2/7/2012 Physician United States
Primary
Concomitant
Retinal Detachment Other Serious 1 Female 2/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Eye Excision Disability 3 Male 2/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Eye Excision Disability 12 Female 2/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Epistaxis Other Serious 1 Female 2/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Retinal Detachment Other Serious 1 Male 2/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2 Male 2/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Extraocular Muscle Disorder Other Serious 1 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Eyelid Oedema Other Serious 1 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Eye Excision Disability 1 Female 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Extraocular Muscle Disorder Disability 1 Female 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Extraocular Muscle Disorder Other Serious 3 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Retinal Pigment Epitheliopathy Other Serious 3 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Extraocular Muscle Disorder Other Serious 2 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Choroidal Dystrophy Other Serious 2 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Retinal Artery Occlusion Other Serious 1 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Retinal Detachment Disability 2 Female 2/7/2012 Other Health Professional United States
Primary
Concomitant
Optic Atrophy Other Serious 1 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 2 Female 2/7/2012 Other Health Professional United States
Primary
Concomitant
Retinal Detachment Disability 2 Male 2/7/2012 Other Health Professional United States
Primary
Concomitant
Extraocular Muscle Disorder Other Serious 1 Male 2/7/2012 Other Health Professional United States
Primary
Concomitant
Retinal Pigment Epitheliopathy Disability 1 Female 2/7/2012 Other Health Professional United States
Primary
Concomitant
Eyelid Ptosis Disability 6 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Extraocular Muscle Disorder Disability 6 Male 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Eye Excision Disability 2 Female 2/7/2012 Other Health Professional United States
Primary
Concomitant
Retinoblastoma Other Serious 1 Female 2/7/2012 Other Health Professional United States
Primary
Concomitant
Eyelid Ptosis Other Serious 1 Male 2/7/2012 Other Health Professional United States
Primary
Concomitant
Pyrexia Death 2/1/2006 85 Male 2/8/2012 Lawyer United States
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 6/8/2009 6 Male 33 lb 2/9/2012 Physician Japan
Primary
Concomitant
Infection Other Serious 8/21/2009 6 Male 35 lb 2/9/2012 Physician Japan
Primary
Concomitant
Haemolytic Anaemia Other Serious 8/21/2009 6 Male 35 lb 2/9/2012 Physician Japan
Primary
Concomitant
Post Transplant Lymphoproliferative Disorder Death 3/6/2009 9 Male 49 lb 2/10/2012 Physician Japan
Primary
Concomitant
Infection Hospitalization 1/29/2009 3 Female 35 lb 2/10/2012 Physician Japan
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1 Female 2/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Eye Excision Disability 30 Male 2/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2 Male 2/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Epistaxis Other Serious 1 Female 2/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Retinal Detachment Other Serious 1 Male 2/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Eye Excision Disability 12 Female 2/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Arterial Disorder Other Serious 1 Male 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Glaucoma Disability 1 Female 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Extraocular Muscle Disorder Disability 6 Male 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Extraocular Muscle Disorder Other Serious 3 Male 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Extraocular Muscle Disorder Other Serious 2 Male 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Retinal Pigment Epitheliopathy Other Serious 1 Male 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Retinal Artery Occlusion Disability 2 Female 2/2/2012 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 2 Female 2/2/2012 Physician United States
Primary
Concomitant
Retinal Detachment Disability 2 Male 2/2/2012 Physician United States
Primary
Concomitant
Extraocular Muscle Disorder Other Serious 1 Male 2/2/2012 Physician United States
Primary
Concomitant
Retinoblastoma Disability 1 Female 2/2/2012 Physician United States
Primary
Concomitant
Eyelid Oedema Disability 2 Female 2/2/2012 Physician United States
Primary
Concomitant
Eyelid Oedema Other Serious 1 Female 2/2/2012 Physician United States
Primary
Concomitant
Retinal Pigment Epitheliopathy Other Serious 1 Male 2/2/2012 Physician United States
Primary
Concomitant
Interstitial Lung Disease Death 6/24/2010 29 Female 99 lb 3/2/2012 Other Health Professional Japan
Primary
Concomitant

Drug Data