Heparin combined with Levofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 11/13/2005 55 Male 1/9/2006 Pharmacist France
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 42 Male 1/10/2006 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
Vaginal Infection Other Serious 10/12/2005 63 Female 1/18/2006 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 1/19/2006 Physician United States
Primary
Secondary
Concomitant
Skin Discolouration Required Intervention 8/23/2005 Female 9/2/2005 United States
Primary
Concomitant
Psychotic Disorder Required Intervention 10/9/2005 63 Male 154 lb 11/7/2005 Pharmacist United States
Primary
Concomitant
Sepsis Syndrome Required Intervention 11/1/2005 23 Female 139 lb 12/5/2005 United States
Primary
Concomitant
Renal Failure Other Serious 55 Male 1/25/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 12/29/2005 63 Male 2/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 24 Female 123 lb 2/21/2006 United States
Primary
Concomitant
Tachycardia Life Threatening 3/4/2006 74 Male 190 lb 3/10/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/29/2005 63 Male 2/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination Other Serious 62 Female 3/31/2006 Pharmacist United States
Primary
Concomitant
Hallucination Other Serious 62 Female 4/14/2006 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Hospitalization 24 Female 123 lb 2/21/2006 United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Life Threatening 4/29/2005 76 Female 143 lb 4/19/2006 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/31/2006 62 Female 140 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Mouth Haemorrhage Death 8/30/2006 76 Female 9/22/2006 Germany
Primary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 10/19/2006 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 48 Male 10/18/2006 Physician United States
Primary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Pyrexia Other Serious 5/18/2006 78 Female 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 11/13/2006 Physician Germany
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 6/26/2006 85 Male 180 lb 12/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 5/18/2007 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/15/2006 71 Female 154 lb 1/14/2007 Pharmacist United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 6/28/2005 59 Female 6/11/2007 Physician United States
Primary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 6/15/2007 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia 6/6/2007 91 Female 6/27/2007 United States
Primary
Concomitant
Overdose Other Serious 7/21/2007 39 Male 144 lb 7/26/2007 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/26/2007 81 Female 141 lb 7/25/2007 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 6/27/2007 Male 146 lb 8/14/2007 Italy
Primary
Concomitant
Respiratory Rate Increased Required Intervention 6/1/2007 48 Female 6/8/2007 United States
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 4/12/2007 Female 127 lb 4/16/2007 Pharmacist United States
Primary
Concomitant
Rash Maculo-papular Hospitalization 73 Male 9/20/2007 United States
Primary
Concomitant
Troponin I Increased Other Serious 6/19/2007 45 Male 11/9/2007 Physician China
Primary
Secondary
Concomitant
Vascular Skin Disorder Other Serious 45 Male 11/15/2007 Consumer United States
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Retinopathy Of Prematurity Hospitalization 11/30/2007 Canada
Primary
Secondary
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Pallor Hospitalization 1/4/2008 Female 189 lb 3/14/2008 Pharmacist United States
Primary
Concomitant
Haemodialysis Required Intervention 1/18/2008 51 Female 134 lb 1/21/2008 Pharmacist United States
Primary
Concomitant
Micturition Disorder Hospitalization 2/15/2008 73 Male 134 lb 4/1/2008 Physician Japan
Primary
Concomitant
Sinusitis Hospitalization 4/23/2007 9 Female 54 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2008 82 Male 4/11/2008 Physician United States
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 4/16/2008 Germany
Primary
Concomitant
Ventricular Tachycardia Life Threatening 3/24/2008 64 Male 162 lb 4/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 2/15/2008 73 Male 134 lb 4/29/2008 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 3/24/2008 64 Male 162 lb 5/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 5/9/2008 Germany
Primary
Concomitant
Leg Amputation Required Intervention 2/24/2005 46 Male 280 lb 5/29/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/21/2007 25 Male 112 lb 6/4/2008 Physician Japan
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/22/2008 82 Female 172 lb 5/2/2008 United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/21/2007 25 Male 112 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/5/2007 25 Male 7/10/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 7/28/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Jaundice Hospitalization 7/21/2008 52 Male 278 lb 8/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neoplasm Progression Required Intervention 8/15/2007 45 Female 175 lb 9/26/2007 Physician United States
Primary
Concomitant
Impaired Gastric Emptying Hospitalization 10/7/2008 Male 11/12/2008 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 10/1/2008 44 Female 10/24/2008 Pharmacist United States
Primary
Concomitant
Tachypnoea Other Serious 16 Female 11/21/2008 Physician Canada
Primary
Secondary
Sepsis Hospitalization 8/21/2008 Male 12/24/2008 Japan
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2008 64 Male 227 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Enterococcal Infection Death 12/9/2008 65 Male 192 lb 1/8/2009 Physician Spain
Primary
Concomitant
Thrombophlebitis Other Serious 12/16/2008 76 Female 251 lb 1/14/2009 Pharmacist United States
Primary
Secondary
Concomitant
Enterococcal Infection Death 12/18/2008 65 Male 192 lb 1/22/2009 Physician Spain
Primary
Concomitant
Vaccination Failure Other Serious 35 Female 2/27/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 Female 116 lb 3/3/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 57 Female 116 lb 3/26/2009 United States
Primary
Secondary
Concomitant
Vaccination Failure Other Serious 35 Female 4/2/2009 Consumer United States
Primary
Concomitant
Death Death 2/1/2004 Female 4/3/2009 Physician Israel
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 4/14/2009 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 4/2/2009 75 Female 128 lb 4/27/2009 Pharmacist United States
Primary
Concomitant
Paraesthesia Oral Life Threatening 3/1/2009 51 Male 3/6/2009 Pharmacist United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 Female 196 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 5/20/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Life Threatening 7/29/2004 Male 218 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 36 Male 7/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 50 Female 7/31/2009 Physician Israel
Primary
Secondary
Concomitant
Urinary Fistula Hospitalization 10/18/2004 54 Male 8/21/2009 Spain
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/12/2009 Male 172 lb 8/26/2009 Spain
Primary
Concomitant
Vomiting Death 3/2/2008 78 Female 9/1/2009 Lawyer United States
Primary
Concomitant
Pyrexia Life Threatening 8/12/2009 Male 172 lb 9/9/2009 Spain
Primary
Concomitant
Vomiting Death 3/2/2008 69 Female 9/8/2009 United States
Primary
Concomitant
Palmar Erythema Life Threatening 6/4/2009 23 Female 230 lb 6/5/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Life Threatening 8/12/2009 Male 172 lb 10/2/2009 Spain
Primary
Concomitant
Vomiting Death 3/2/2008 78 Female 10/17/2009 United States
Primary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/12/2009 Male 172 lb 11/16/2009 Spain
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 8/19/2009 Female 88 lb 12/8/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Disability 4/15/2009 50 Female 157 lb 12/10/2009 Pharmacist United States
Primary
Concomitant
Somnolence Required Intervention 10/20/2009 25 Female 206 lb 10/21/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/19/2009 81 Female 88 lb 1/4/2010 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Death 11/4/2009 Female 98 lb 1/6/2010 Canada
Primary
Secondary
Concomitant
Disease Progression Hospitalization 1/14/2009 2/8/2010 Physician France
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/19/2009 81 Female 88 lb 2/18/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 63 Female 2/19/2010 Lawyer United States
Primary
Concomitant
Disease Progression Hospitalization 1/14/2009 2/23/2010 Physician France
Primary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 3/4/2010 Other Health Professional United States
Primary
Concomitant
Treatment Related Secondary Malignancy Death 63 Male 3/1/2010 Physician Spain
Primary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 3/9/2010 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 12/5/2008 3/26/2010 Physician France
Primary
Concomitant
Vascular Occlusion Other Serious 45 Male 3/29/2010 Physician United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/5/2008 4/8/2010 Physician France
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/7/2010 United States
Primary
Concomitant
Pyrexia Hospitalization 4/22/2010 69 Male 158 lb 5/2/2010 Physician India
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 79 Female 5/18/2010 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 79 Female 5/25/2010 United States
Primary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/9/2010 United States
Primary
Secondary
Concomitant
Surgery Other Serious 2/21/2010 56 Male 278 lb 6/11/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 1/1/2009 61 Female 6/15/2010 Physician Germany
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Life Threatening 5/7/2010 73 Male 186 lb 7/1/2010 Pharmacist United States
Primary
Concomitant
Neutropenia Hospitalization 12/3/2009 64 Female 183 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 79 Female 7/9/2010 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/9/2010 62 Male 108 lb 7/15/2010 Pharmacist United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2004 83 Male 182 lb 8/2/2010 United States
Primary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 7/28/2010 United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 8/4/2010 Other Health Professional Algeria
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/16/2007 49 Male 303 lb 8/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2004 83 Male 182 lb 8/17/2010 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 10/10/2008 8/19/2010 Physician France
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2004 83 Male 182 lb 8/20/2010 United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 59 Female 132 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/3/2009 64 Female 183 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 8/30/2010 United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 6/1/2009 59 Female 132 lb 9/1/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2003 42 Male 206 lb 9/3/2010 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Life Threatening 10/11/2007 51 Female 165 lb 9/3/2010 Physician France
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 9/7/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2003 42 Male 206 lb 9/10/2010 Other Health Professional United States
Primary
Concomitant

Drug Data