Heparin combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Function Abnormal Hospitalization 11/1/2005 37 Male 163 lb 2/6/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 10/29/2005 37 Male 163 lb 2/8/2006 Physician Japan
Primary
Concomitant
Bradycardia Life Threatening 12/15/2005 63 Female 2/8/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/1/2006 80 Female 6/23/2006 Physician Germany
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/8/2006 78 Male 176 lb 8/15/2006 Bulgaria
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 137 lb 9/15/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/19/2006 28 Female 137 lb 9/22/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 115 lb 9/25/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 115 lb 3/5/2007 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/8/2006 78 Male 176 lb 6/25/2007 Bulgaria
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/10/2006 59 Female 7/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 2/19/2007 62 Male 8/8/2007 Physician United States
Primary
Secondary
Concomitant
Rash Life Threatening 10/16/2007 65 Male 11/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Melaena Other Serious 96 Male 12/21/2007 Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Myocardial Ischaemia Other Serious 77 Male 112 lb 5/13/2008 Other Health Professional Japan
Primary
Concomitant
Myocardial Ischaemia Other Serious 77 Male 112 lb 5/21/2008 Other Health Professional Japan
Primary
Concomitant
Vasospasm Other Serious 3/1/2006 49 Female 6/4/2008 Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/1/2006 49 Female 6/4/2008 Japan
Primary
Secondary
Concomitant
Hypertensive Crisis Life Threatening 4/30/2008 7/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 6/22/2008 63 Male 177 lb 10/25/2008 United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 1/16/2009 Lawyer United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 2/19/2009 Lawyer United States
Primary
Concomitant
Mental Status Changes Other Serious 8/1/2008 Male 2/24/2009 Pharmacist United States
Primary
Concomitant
Vasodilatation 12/26/2008 61 Male 2/20/2009 Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/13/2009 33 Male 8/21/2009 France
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 55 Male 10/9/2009 Japan
Primary
Concomitant
Thrombosis In Device Other Serious 55 Female 115 lb 10/22/2009 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 10/10/2008 63 Male 157 lb 11/30/2009 Other Health Professional Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 8/26/2009 80 Male 183 lb 12/3/2009 Physician Russian Federation
Primary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 8/19/2009 Female 88 lb 12/8/2009 Physician Japan
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 8/26/2009 80 Male 183 lb 12/9/2009 Physician Russian Federation
Primary
Concomitant
Pain In Extremity Other Serious 11/27/2009 56 Female 200 lb 12/17/2009 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/19/2009 81 Female 88 lb 1/4/2010 Physician Japan
Primary
Secondary
Concomitant
Appendicitis Other Serious 2/8/2009 37 Male 198 lb 2/12/2010 Physician Japan
Primary
Concomitant
Gingival Bleeding Hospitalization 1/25/2010 Male 186 lb 2/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 8/19/2009 81 Female 88 lb 2/18/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 1/12/2006 81 Female 4/6/2010 Japan
Primary
Secondary
Concomitant
Gingival Bleeding Hospitalization 1/25/2010 61 Male 186 lb 4/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Urticaria Life Threatening 6/17/2010 47 Male 9/28/2010 France
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stupor Hospitalization 3/3/1982 83 Male 132 lb 10/27/2010 Physician Germany
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 62 Male 11/17/2010 United States
Primary
Concomitant
Sudden Death Other Serious 9/1/2010 59 Male 143 lb 12/23/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 12/29/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 9/1/2010 56 Male 212 lb 1/4/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/5/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Rash Macular Hospitalization 11/6/2010 64 Female 1/17/2011 Physician France
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 1/24/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 53 Male 1/26/2011 Physician China
Primary
Concomitant
Interacting
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 2/7/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Fear Other Serious 9/21/2005 54 Female 172 lb 3/6/2011 Other Health Professional United States
Primary
Concomitant
Renal Impairment Death 9/21/2005 54 Female 172 lb 3/6/2011 Other Health Professional United States
Primary
Concomitant
Transplant Failure Other Serious 11/12/2009 67 Female 273 lb 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 11/12/2009 67 Female 273 lb 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Injury Hospitalization 10/2/2005 52 Female 220 lb 3/23/2011 Physician United States
Primary
Concomitant
Anhedonia Other Serious 10/2/2005 52 Female 220 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Sudden Death Other Serious 8/29/2010 59 Male 143 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Cardiomyopathy Hospitalization 2/20/2008 48 Female 180 lb 3/17/2011 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/6/2011 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anhedonia Death Female 247 lb 4/13/2011 Consumer United States
Primary
Concomitant
Multi-organ Failure Death 3/29/2004 85 Male 161 lb 4/14/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Death Female 247 lb 4/13/2011 Lawyer United States
Primary
Concomitant
Stress Death 7/18/2003 79 Female 161 lb 4/15/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Anhedonia Hospitalization 12/15/2005 56 Male 146 lb 4/18/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 6/28/2005 69 Female 198 lb 4/18/2011 Other Health Professional United States
Primary
Concomitant
Injury Other Serious 1/1/2003 76 Female 160 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Fear Of Death Other Serious 4/27/2001 78 Female 185 lb 4/20/2011 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 11/12/2009 67 Female 273 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Oliguria Hospitalization 11/12/2009 67 Female 273 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Emotional Distress Other Serious 3/15/2006 68 Male 217 lb 4/26/2011 Lawyer United States
Primary
Concomitant
Anxiety Hospitalization 7/20/2002 64 Male 172 lb 4/28/2011 Lawyer United States
Primary
Concomitant
Chills Death 3/6/2011 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Anhedonia Death Female 247 lb 4/29/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 3/15/2006 68 Male 217 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Disorder Other Serious 1/22/2005 78 Male 175 lb 5/4/2011 Consumer United States
Primary
Concomitant
Cardiac Disorder Other Serious 43 Male 220 lb 5/9/2011 Other Health Professional United States
Primary
Concomitant
Productive Cough Other Serious 3/15/2006 68 Male 217 lb 5/7/2011 Consumer United States
Primary
Concomitant
Multi-organ Failure Other Serious 1/10/2006 78 Male 182 lb 5/9/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 82 Female 115 lb 5/3/2011 United States
Primary
Concomitant
Electrocardiogram T Wave Abnormal Other Serious 3/17/2009 66 Female 273 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Anxiety Other Serious 3/15/2006 68 Male 217 lb 5/16/2011 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 12/26/2007 73 Male 174 lb 5/21/2011 Other Health Professional United States
Primary
Concomitant
Injury Other Serious Female 172 lb 5/23/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 11/1/2003 65 Female 174 lb 5/24/2011 Other Health Professional United States
Primary
Concomitant
Stress Other Serious 6/3/2006 69 Male 201 lb 5/24/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 64 Male 216 lb 5/24/2011 Consumer United States
Primary
Concomitant
Mental Status Changes Other Serious 11/12/2009 67 Female 273 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anxiety Hospitalization 3/15/2002 44 Male 233 lb 5/28/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 51 Female 5/31/2011 Lawyer United States
Primary
Concomitant
Anhedonia Other Serious 5/17/2007 58 Male 150 lb 5/31/2011 Other Health Professional United States
Primary
Concomitant
Fear Death 6/3/2006 69 Male 201 lb 6/1/2011 Consumer United States
Primary
Concomitant
Resuscitation Hospitalization 3/6/2011 6/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Emotional Distress Other Serious 3/15/2006 68 Male 217 lb 6/21/2011 Physician United States
Primary
Concomitant
Aortic Dilatation Hospitalization 88 Female 6/20/2011 United States
Primary
Concomitant
Pain Other Serious 7/7/2006 73 Male 200 lb 7/13/2011 Other Health Professional United States
Primary
Concomitant
Death Other Serious 7/1/2004 72 Male 220 lb 7/14/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/13/2004 60 Female 245 lb 7/14/2011 Lawyer United States
Primary
Concomitant
Stress Other Serious 54 Male 227 lb 7/15/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/5/2005 55 Female 119 lb 7/18/2011 Other Health Professional United States
Primary
Concomitant
Death Other Serious 9/8/2006 63 Female 166 lb 7/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 1/1/2003 76 Female 160 lb 7/20/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 3/15/2006 68 Male 217 lb 7/27/2011 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Other Serious 54 Male 227 lb 8/2/2011 Lawyer United States
Primary
Concomitant
Renal Injury Other Serious 1/1/2003 76 Female 160 lb 8/8/2011 Other Health Professional United States
Primary
Concomitant
Pancytopenia Hospitalization 7/6/2011 43 Female 8/9/2011 Physician France
Primary
Concomitant
Nervousness Other Serious Female 208 lb 8/10/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious Female 208 lb 8/15/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Other Serious 6/28/2005 69 Female 198 lb 8/17/2011 Lawyer United States
Primary
Concomitant
Angiopathy Hospitalization 11/25/2010 62 Male 9/7/2011 Physician Japan
Primary
Concomitant
Injury Other Serious 10/2/2005 52 Female 220 lb 9/15/2011 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/22/2005 78 Male 174 lb 9/16/2011 Other Health Professional United States
Primary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Ankle Fracture Other Serious 6/23/2011 7 Female 46 lb 9/19/2011 Pharmacist United States
Primary
Concomitant
Angiopathy Hospitalization 11/25/2010 62 Male 9/22/2011 Physician Japan
Primary
Concomitant
Puncture Site Haemorrhage Hospitalization 2/7/2010 60 Male 258 lb 9/26/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious 5/20/2009 49 Male 150 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Gingival Bleeding Hospitalization 1/25/2010 61 Male 186 lb 9/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain Death 5/26/2006 79 Male 181 lb 9/27/2011 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 10/10/2009 87 Female 158 lb 9/28/2011 Physician Japan
Primary
Concomitant
Multi-organ Failure Death 5/26/2006 79 Male 181 lb 9/29/2011 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 2/9/2011 79 Female 112 lb 10/3/2011 Physician Japan
Primary
Concomitant
Injury Death 3/23/2004 85 Male 161 lb 10/6/2011 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Disability 8/29/2010 59 Male 143 lb 9/28/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Vasodilatation Hospitalization 3/17/2009 66 Female 273 lb 10/18/2011 Physician United States
Primary
Secondary
Concomitant
Injury Death 12/26/2007 73 Male 174 lb 10/20/2011 Other Health Professional United States
Primary
Concomitant
Haemodynamic Instability Other Serious 11/12/2009 67 Female 273 lb 10/24/2011 Physician United States
Primary
Secondary
Concomitant
Rash Erythematous 1/29/2010 78 Male 10/24/2011 Physician Japan
Primary
Concomitant
Concomitant Disease Progression Hospitalization 7/14/2010 56 Male 272 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Pain Death 12/26/2007 73 Male 174 lb 10/31/2011 Other Health Professional United States
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 2/9/2011 79 Female 112 lb 11/4/2011 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Death 11/4/2011 72 Male 11/10/2011 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 10/26/2011 49 Male 150 lb 11/11/2011 Physician Japan
Primary
Concomitant
Anxiety Hospitalization 6/28/2005 69 Female 198 lb 11/21/2011 Lawyer United States
Primary
Concomitant
Anhedonia Other Serious 3/21/2004 73 Male 220 lb 11/30/2011 Lawyer United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 2/9/2011 79 Female 112 lb 12/1/2011 Physician Japan
Primary
Concomitant

Drug Data