Glyburide combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coronary Artery Disease Hospitalization 5/1/2005 56 Male 1/5/2006 Consumer United States
Primary
Concomitant
Quadruple Vessel Bypass Graft Hospitalization 5/1/2005 56 Male 1/20/2006 Consumer United States
Primary
Concomitant
Ventricular Dysfunction Life Threatening 8/30/2005 Male 139 lb 2/8/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 12/12/2005 66 Female 146 lb 2/9/2006 Physician United States
Primary
Concomitant
Left Ventricular End-diastolic Pressure Increased Hospitalization 3/9/2004 65 Male 271 lb 2/16/2006 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious 37 Male 3/6/2006 Consumer France
Primary
Secondary
Nephritis Interstitial Other Serious Male 3/17/2006 Consumer France
Primary
Secondary
Myocardial Infarction Other Serious 1/1/2000 45 Male 196 lb 3/31/2006 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization 3/22/2006 88 Male 193 lb 4/6/2006 Pharmacist United States
Primary
Concomitant
Polytraumatism Other Serious 1/1/2000 45 Male 196 lb 4/12/2006 Lawyer United States
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/1/2002 43 Female 196 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Malignant Melanoma Other Serious 6/16/2001 52 Male 209 lb 4/24/2006 Lawyer United States
Primary
Concomitant
Vomiting Female 4/21/2006 United States
Primary
Secondary
Blood Glucose Increased Other Serious 69 Female 4/26/2006 Pharmacist Canada
Primary
Concomitant
Cold Sweat Other Serious 3/21/2006 57 Male 324 lb 3/21/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 1/4/2005 85 Male 180 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2001 52 Male 209 lb 5/1/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Required Intervention 3/16/2006 74 Male 5/9/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Decreased Required Intervention 3/2/2006 54 Male 552 lb 3/23/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased 1/1/2005 63 Male 5/30/2006 Consumer United States
Primary
Concomitant
Chills 11/1/2005 72 Male 185 lb 5/30/2006 Consumer United States
Primary
Concomitant
Weight Decreased 4/10/2006 Male 214 lb 6/29/2006 Pharmacist United States
Primary
Concomitant
Vision Blurred Disability 1/23/2006 Male 184 lb 6/26/2006 Pharmacist United States
Primary
Concomitant
Hyperglycaemia Hospitalization 49 Female 5/8/2006 United States
Primary
Concomitant
Hyperglycaemia Hospitalization 49 Female 5/8/2006 United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 8/1/2005 78 Male 202 lb 7/21/2006 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/22/2005 74 Male 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 11/15/2005 74 Male 183 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
Abdominal Discomfort 3/29/2006 Female 8/1/2006 Consumer United States
Primary
Concomitant
Walking Aid User Hospitalization 4/24/2006 52 Male 152 lb 7/31/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Physician Canada
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Canada
Primary
Concomitant
Malnutrition Hospitalization 1/1/2006 67 Male 132 lb 9/14/2006 Physician Canada
Primary
Concomitant
Pruritus Other Serious 8/14/2006 56 Male 217 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Monoparesis Hospitalization 3/11/2006 73 Male 142 lb 10/6/2006 Physician Japan
Primary
Concomitant
Wheezing Other Serious 9/26/2006 78 Male 165 lb 10/23/2006 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 7/18/2006 58 Male 419 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Lactic Acidosis Hospitalization 35 Male 10/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 12/21/2006 Physician Canada
Primary
Concomitant
Ascites Hospitalization 10/1/2006 75 Female 1/26/2007 Other Health Professional Sweden
Primary
Concomitant
Vomiting Hospitalization 1/1/2005 80 Female 4/5/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pallanaesthesia Hospitalization 9/8/2006 24 Male 4/13/2007 Japan
Primary
Secondary
Vomiting Required Intervention 55 Male 5/9/2007 United States
Primary
Concomitant
Vertigo Hospitalization 3/1/2007 63 Female 110 lb 5/18/2007 Physician Venezuela
Primary
Concomitant
Hyperglycaemia Other Serious 64 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 1/6/2007 51 Female 191 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 5/8/2007 55 Female 155 lb 8/2/2007
Primary
Concomitant
Feeling Abnormal Hospitalization 6/16/2007 Male 139 lb 8/9/2007 Physician Japan
Primary
Concomitant
Feeling Abnormal Hospitalization 6/16/2007 Male 139 lb 9/4/2007 Physician Japan
Primary
Concomitant
Urosepsis Required Intervention 85 Female 9/18/2007 Netherlands
Primary
Concomitant
Kidney Infection Hospitalization 9/1/2007 87 Female 9/26/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 62 Male 212 lb 10/2/2007 United States
Primary
Concomitant
Lip Exfoliation 4/15/2007 Female 10/2/2007 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 62 Male 212 lb 10/18/2007 United States
Primary
Concomitant
Tremor Other Serious 62 Male 212 lb 10/25/2007 United States
Primary
Concomitant
Cholangitis Other Serious 11/8/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 11/6/2007 Male 170 lb 11/7/2007 Pharmacist United States
Primary
Concomitant
Rash Other Serious 1/1/2007 Female 137 lb 11/20/2007 Other Health Professional Canada
Primary
Concomitant
Meningitis Death 11/10/2006 66 Female 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Seronegative Arthritis Hospitalization 7/1/2006 59 Female 11/26/2007
Primary
Concomitant
Cholangitis Other Serious 12/1/2007 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 11/8/2007 Female 193 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/15/2007 74 Female 157 lb 1/23/2008 Other Health Professional France
Primary
Secondary
Concomitant
Drug Toxicity Death 77 3/20/2008 Pharmacist United States
Primary
Secondary
Drug Toxicity Death 77 3/27/2008 Pharmacist United States
Primary
Secondary
Vomiting Required Intervention 78 Female 4/10/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 3/1/2008 69 Male 243 lb 4/17/2008 Consumer United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 65 Female 4/22/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/24/2007 Female 112 lb 5/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 11/24/2007 Female 112 lb 5/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Drug Toxicity Death 27 6/20/2008 Pharmacist United States
Primary
Secondary
Urinary Tract Infection Death 56 Male 10/6/2008 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Ulcer Other Serious 1/1/2008 81 Female 130 lb 10/17/2008 Physician United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 9/1/2008 68 Female 10/17/2008 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 6/29/2006 60 Male 173 lb 10/17/2008 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 67 Female 10/17/2008 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 3/1/2008 79 Female 183 lb 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paralysis Hospitalization 5/1/2006 41 Male 365 lb 10/20/2008 Consumer United States
Primary
Concomitant
Gastrointestinal Ulcer Other Serious 1/1/2008 81 Female 130 lb 10/20/2008 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 9/19/2008 63 Male 10/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 8/16/2008 65 Female 10/17/2008 Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Metastatic Death 1/1/2007 Male 10/24/2008 Physician United States
Primary
Concomitant
Scotoma Other Serious 7/1/2008 Male 10/27/2008 Pharmacist Canada
Primary
Concomitant
Social Fear Other Serious 10/17/2008 53 Male 249 lb 10/29/2008 Consumer United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 8/15/2008 65 Female 10/29/2008 Japan
Primary
Secondary
Concomitant
Nephrolithiasis 5/16/2008 Male 12/12/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Death 1/30/2008 80 Female 12/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 2/17/2006 52 Male 280 lb 12/19/2008 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Renal Failure Acute Life Threatening 7/1/2008 77 Female 3/20/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 40 Female 166 lb 5/14/2009 United States
Primary
Concomitant
Vaginal Discharge Other Serious 1/1/2004 53 Female 190 lb 5/20/2009 United States
Primary
Concomitant
Rash Pruritic Male 5/15/2009 Physician United States
Primary
Concomitant
Abdominal Distension Female 5/15/2009 United States
Primary
Concomitant
Skin Haemorrhage 1/19/2009 60 Female 165 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Vomiting 42 Female 5/15/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred 12/15/2008 61 Female 5/15/2009 United States
Primary
Concomitant
Pain In Extremity Other Serious 4/5/2009 81 Male 179 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Other Serious 5/25/2009 71 Female 161 lb 6/2/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/20/2007 58 Male 207 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Other Serious 2/20/2004 41 Male 181 lb 6/4/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 4/19/2005 52 Female 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 9/4/2003 53 Male 175 lb 6/4/2009 Other Health Professional United States
Primary
Concomitant
Coronary Artery Bypass Hospitalization 5/26/2009 Male 6/5/2009 Canada
Primary
Concomitant
Rectal Cancer Other Serious 3/13/2009 Female 146 lb 6/8/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2007 Female 260 lb 5/29/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 46 Male 250 lb 6/10/2009 United States
Primary
Concomitant
Injection Site Pain 6/21/2008 Female 128 lb 6/11/2009 United States
Primary
Concomitant
Blood Pressure Increased 1/5/2009 Male 200 lb 6/11/2009 Consumer United States
Primary
Concomitant
Swelling Face 1/1/2009 Female 285 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity 2/1/2009 Male 240 lb 6/12/2009 United States
Primary
Concomitant
Oedema Peripheral 4/25/2009 Female 127 lb 6/12/2009 Consumer United States
Primary
Concomitant
Elbow Deformity 3/1/2009 Female 183 lb 6/12/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/1/2005 65 Male 220 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Shock Hospitalization 11/1/2006 58 Female 6/15/2009 Other Health Professional United States
Primary
Concomitant
Paralysis Hospitalization 5/1/2006 41 Male 365 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2005 56 Male 180 lb 6/15/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 88 Male 200 lb 6/15/2009 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 5/1/2009 Female 430 lb 6/11/2009 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 8/6/1999 47 Male 232 lb 7/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 42 Male 222 lb 7/23/2009 United States
Primary
Concomitant
Somnolence 3/23/2008 66 Female 8/14/2009 Other Health Professional United States
Primary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 9/16/2009 Other Health Professional France
Primary
Secondary
Vulvovaginal Mycotic Infection Other Serious 8/3/2003 44 Female 273 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 65 Male 9/22/2009 United States
Primary
Concomitant
Eye Haemorrhage Other Serious 73 Female 168 lb 10/1/2009 Consumer United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Unemployment Hospitalization 1/20/2006 73 Male 163 lb 9/22/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 8/26/2009 67 Male 211 lb 10/7/2009 Pharmacist Canada
Primary
Concomitant
Respiratory Failure Hospitalization 12/27/2006 Female 10/13/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/1/2002 51 Female 230 lb 10/14/2009 United States
Primary
Concomitant
Skin Laceration Other Serious 5/1/2009 Male 245 lb 10/14/2009 Physician United States
Primary
Concomitant
Ill-defined Disorder Disability Male 10/15/2009 United States
Primary
Concomitant
Ill-defined Disorder Disability Female 215 lb 10/15/2009 United States
Primary
Concomitant
Pain Other Serious 9/28/2009 Male 250 lb 10/12/2009 Consumer United States
Primary
Concomitant
Ill-defined Disorder Disability Male 274 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
Death Death 10/4/2009 Male 227 lb 10/16/2009 Physician United States
Primary
Secondary
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 10/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 10/28/2009 Other Health Professional France
Primary
Secondary
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 11/4/2009 Other Health Professional France
Primary
Secondary
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 11/13/2009 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 11/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 206 lb 11/30/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/21/2009 Physician United States
Primary
Concomitant
Somnambulism Death 11/1/2009 48 Male 12/14/2009 Physician United States
Primary
Concomitant

Drug Data