Glimepiride combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased 11/22/2005 60 Male 311 lb 1/20/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis 2/19/2006 84 Male 5/24/2006 Switzerland
Primary
Secondary
Concomitant
Weight Decreased 5/1/2006 66 Female 225 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 5/1/2006 66 Female 212 lb 10/16/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/9/2004 176 lb 2/23/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/9/2006 66 Male 3/10/2007 Physician Canada
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2007 65 Male 4/20/2007 Japan
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 1/5/2007 65 Male 5/21/2007 Japan
Primary
Concomitant
Weight Increased 10/1/2006 Male 7/26/2007 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 50 Female 8/17/2007 Physician France
Primary
Concomitant
Weight Decreased 5/6/2006 66 Female 212 lb 7/11/2007 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 7/6/2007 50 Male 9/4/2007 Other Health Professional Philippines
Primary
Secondary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/14/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/18/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/27/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/15/2007 83 Female 10/30/2007 Italy
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/1/2006 64 Male 12/14/2007 Consumer United States
Primary
Concomitant
Skin Haemorrhage Other Serious 12/1/2006 72 Male 12/13/2007 Denmark
Primary
Secondary
Concomitant
Tremor 9/20/2007 61 Female 10/9/2007 Consumer United States
Primary
Concomitant
Potentiating Drug Interaction Life Threatening 12/12/2007 66 Male 1/28/2008 Pharmacist Netherlands
Primary
Concomitant
Pneumonia Hospitalization 12/1/2006 64 Male 2/27/2008 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/6/2008 80 Male 5/20/2008 United Kingdom
Primary
Concomitant
Left Ventricular Dysfunction Hospitalization 1/1/2004 80 Male 5/23/2008 United Kingdom
Primary
Concomitant
Pemphigoid Hospitalization 3/15/2008 83 Male 6/27/2008 Other Health Professional France
Primary
Secondary
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 73 Female 8/5/2008 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 73 Female 134 lb 9/3/2008 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 57 Male 9/8/2008 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious Male 210 lb 10/3/2008 Physician United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 10/1/2008 Male 11/10/2008 Other Health Professional Germany
Primary
Concomitant
Weight Decreased Other Serious 7/17/2008 58 Male 210 lb 11/7/2008 Physician United States
Primary
Concomitant
Pemphigoid Hospitalization 3/15/2008 83 Male 11/21/2008 Other Health Professional France
Primary
Secondary
Pruritus 11/26/2008 United States
Primary
Concomitant
Pneumonia Life Threatening 10/1/2008 65 Female 12/9/2008 Physician Austria
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 75 Female 12/18/2008 Other Health Professional Poland
Primary
Secondary
Pemphigoid Hospitalization 3/15/2008 83 Male 12/23/2008 Other Health Professional France
Primary
Secondary
Death Death 10/3/2008 1/8/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 1/23/2009 Other Health Professional France
Primary
Concomitant
Malaise Other Serious 1/1/2004 Male 178 lb 1/29/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Death 10/3/2008 1/30/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 11/15/2008 61 Male 305 lb 2/5/2009 Sweden
Primary
Concomitant
Swelling Other Serious 7/26/2004 Male 178 lb 2/6/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/15/2008 61 Male 305 lb 3/12/2009 Other Health Professional Sweden
Primary
Concomitant
Renal Failure Hospitalization 11/15/2008 61 Male 305 lb 3/17/2009 Sweden
Primary
Concomitant
Bladder Transitional Cell Carcinoma Stage 0 Required Intervention 10/7/2008 77 Male 241 lb 3/25/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 Male 4/30/2009 Consumer United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 5/8/2008 Male 142 lb 5/5/2009 Physician Germany
Primary
Secondary
Concomitant
Meningitis Hospitalization 5/20/2006 53 Female 5/19/2009 United States
Primary
Concomitant
Pleurisy Hospitalization 1/5/2009 76 Female 5/28/2009 Japan
Primary
Concomitant
Renal Failure Acute Death 7/7/2009 76 Male 7/28/2009 Physician Germany
Primary
Concomitant
Renal Failure Acute Life Threatening 7/7/2009 77 Male 7/29/2009 Physician Germany
Primary
Concomitant
Nausea Hospitalization 64 Female 8/11/2009 United States
Primary
Concomitant
Pruritus 1/1/2005 Female 8/21/2009 United States
Primary
Concomitant
Nausea Hospitalization 64 Female 8/20/2009 Lawyer United States
Primary
Concomitant
Syncope Hospitalization 45 Male 213 lb 8/28/2009 United States
Primary
Concomitant
Syncope Hospitalization 45 Male 213 lb 9/8/2009 United States
Primary
Concomitant
Localised Infection Hospitalization Female 128 lb 9/16/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 82 Female 9/10/2009 United States
Primary
Concomitant
Tinnitus 1/1/1998 64 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 6/5/2007 44 Male 213 lb 9/18/2009 United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Pancreatitis Hospitalization 9/1/2009 Male 240 lb 9/30/2009 Consumer United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 10/8/2009 Physician Netherlands
Primary
Concomitant
Heart Rate Increased Other Serious 1/1/2008 59 Female 240 lb 10/21/2009 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 82 Female 10/18/2009 United States
Primary
Concomitant
Surgery Hospitalization 55 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 82 Female 10/26/2009 United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 55 Female 10/26/2009 United States
Primary
Concomitant
Pleurisy Hospitalization 1/5/2008 76 Female 10/30/2009 Japan
Primary
Concomitant
Sinus Tachycardia Hospitalization 55 Female 11/4/2009 United States
Primary
Concomitant
Flushing 8/14/2009 Male 275 lb 11/25/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 11/16/2009 United States
Primary
Concomitant
Musculoskeletal Pain Hospitalization 11/16/2009 60 Female 11/20/2009 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 11/18/2009 79 Male 330 lb 11/25/2009 Other Health Professional United States
Primary
Concomitant
Multiple Injuries Other Serious 87 Female 12/11/2009 United States
Primary
Concomitant
Pancreatitis Hospitalization 9/1/2009 69 Male 240 lb 11/17/2009 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Life Threatening 10/13/2009 Female 12/23/2009 Physician Hungary
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 77 Female 132 lb 12/24/2009 Other Health Professional France
Primary
Concomitant
Stress Other Serious 1/1/2008 Female 165 lb 12/28/2009 Consumer United States
Primary
Concomitant
Death Death Female 1/5/2010 Consumer United States
Primary
Concomitant
Vascular Resistance Systemic Increased Other Serious 77 Female 132 lb 1/4/2010 Other Health Professional United States
Primary
Concomitant
Wound Hospitalization 1/7/2007 49 Male 1/8/2010 United States
Primary
Concomitant
Weight Decreased 64 Female 1/7/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 82 Female 1/21/2010 United States
Primary
Concomitant
Weight Decreased 64 Female 1/21/2010 United States
Primary
Concomitant
Hepatic Steatosis Hospitalization 77 Female 132 lb 2/2/2010 Physician United States
Primary
Concomitant
Pleurisy Hospitalization 1/5/2008 76 Female 2/4/2010 Japan
Primary
Concomitant
Personality Change Life Threatening 8/13/2008 81 Male 128 lb 2/16/2010
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 10/13/2009 Female 3/2/2010 Physician Hungary
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 Male 179 lb 3/22/2010 Consumer United States
Primary
Concomitant
Muscular Weakness Hospitalization 4/5/2010 64 Male 200 lb 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 Male 4/20/2010 Physician Netherlands
Primary
Concomitant
Disease Progression Death 4/19/2010 65 Male 200 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/21/2010 49 Female 192 lb 5/10/2010 Physician Germany
Primary
Concomitant
Interacting
Sepsis Other Serious 5/9/2010 82 Male 228 lb 5/20/2010 Consumer United States
Primary
Concomitant
Muscle Spasms Female 230 lb 6/16/2010 Consumer United States
Primary
Concomitant
Vision Blurred 5/13/2010 71 Male 200 lb 6/16/2010 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 6/1/2007 73 Female 185 lb 6/29/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Death Female 7/6/2010 Other Health Professional United States
Primary
Concomitant
Splenomegaly Hospitalization 1/1/2010 67 Female 294 lb 7/13/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2010 74 Male 7/15/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 65 Female 183 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 Male 8/4/2010 Physician Netherlands
Primary
Concomitant
Oedema Peripheral 64 Male 381 lb 8/13/2010 Consumer United States
Primary
Concomitant
Lactic Acidosis 8/7/2010 40 Female 277 lb 8/11/2010 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2006 53 Female 163 lb 9/8/2010 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/25/2010 54 Male 269 lb 9/9/2010 Physician Denmark
Primary
Concomitant
Blood Glucose Increased Hospitalization 2/1/2010 79 Male 9/7/2010 Brazil
Primary
Concomitant
Weight Increased 12/1/2009 43 Female 204 lb 9/14/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 65 Female 9/23/2010 United States
Primary
Concomitant
Syncope Hospitalization 12/1/2009 65 Female 142 lb 10/13/2010 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 75 Male 10/19/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Speech Disorder 80 Male 10/13/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 68 Male 179 lb 11/1/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2009 65 Female 142 lb 11/5/2010 Physician United States
Primary
Concomitant
Wheezing Hospitalization 6/2/2010 68 Male 194 lb 11/3/2010 Physician United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 11/18/2009 79 Male 330 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Myalgia 73 Male 220 lb 12/14/2010 Consumer United States
Primary
Concomitant
Epistaxis Hospitalization 7/24/2010 78 Male 200 lb 8/4/2010 Pharmacist United States
Primary
Concomitant
Contusion 12/1/2010 63 Male 1/6/2011 Consumer
Primary
Concomitant
Dizziness Hospitalization 12/15/2010 62 Female 1/31/2011 Consumer
Primary
Concomitant
Dyskinesia Hospitalization 1/17/2011 2/9/2011 Consumer United States
Primary
Concomitant
Ventilation Perfusion Mismatch Other Serious 9/10/2010 2/28/2011 Other Health Professional United States
Primary
Concomitant
Bile Duct Cancer Death 70 Male 266 lb 3/17/2011 Other Health Professional United States
Primary
Concomitant
Stress Other Serious 7/6/2007 75 Male 145 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Anticonvulsant Drug Level Above Therapeutic Hospitalization 64 Female 4/25/2011 United States
Primary
Concomitant
Drug Level Below Therapeutic 3/8/2011 51 Male 5/6/2011 Physician United States
Primary
Concomitant
Blood Bilirubin Increased Other Serious 4/1/2011 77 Male 5/11/2011 Pharmacist Japan
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2006 62 Female 6/2/2011 Physician Italy
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 4/26/2011 77 Male 6/13/2011 Pharmacist Japan
Primary
Concomitant
Hypoglycaemia Life Threatening 1/24/2011 80 Male 198 lb 6/20/2011 Physician Germany
Primary
Concomitant
Fall Other Serious 5/1/2011 70 Female 230 lb 6/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 4/26/2011 77 Male 6/22/2011 Pharmacist Japan
Primary
Concomitant
Hypoglycaemia Life Threatening 1/24/2011 80 Male 198 lb 6/23/2011 Other Health Professional Germany
Primary
Concomitant
Coma Life Threatening 1/24/2011 80 Male 198 lb 6/9/2011 Germany
Primary
Concomitant
Arteriosclerosis Coronary Artery Other Serious Male 241 lb 7/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Swelling Face Hospitalization Female 209 lb 7/20/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death 7/6/2007 75 Male 146 lb 8/2/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization Female 8/3/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Dizziness Female 8/6/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death 7/6/2007 75 Male 146 lb 8/11/2011 Lawyer United States
Primary
Concomitant
Duodenal Ulcer Other Serious 88 Female 8/8/2011 Physician Norway
Primary
Secondary
Concomitant
Dehydration Hospitalization 88 Female 8/10/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Dyspnoea Hospitalization Female 209 lb 8/19/2011 Consumer United States
Primary
Concomitant
Alanine Aminotransferase Increased Death 12/28/2010 83 Female 99 lb 8/26/2011 Physician Japan
Primary
Concomitant
Cardiac Disorder Other Serious 9/1/2009 58 Male 241 lb 8/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Asthenia Other Serious 5/1/2011 70 Female 230 lb 9/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Retinal Detachment Other Serious 8/26/2011 71 Female 168 lb 9/6/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data