Gliclazide combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 8/13/2000 Female 1/3/2006 Australia
Primary
Concomitant
Chest Pain Hospitalization 10/21/1998 Male 1/4/2006 Australia
Primary
Concomitant
Respiratory Failure Hospitalization 12/10/1999 Male 1/4/2006 France
Primary
Concomitant
Hypertension Other Serious 2/27/2001 Male 1/4/2006 France
Primary
Concomitant
Weight Decreased Other Serious 12/1/2002 Female 1/4/2006 France
Primary
Concomitant
Thrombocytopenic Purpura Hospitalization 8/14/2002 Male 1/4/2006 Australia
Primary
Concomitant
Pituitary Tumour Benign Hospitalization 12/13/2001 Female 1/4/2006 Australia
Primary
Concomitant
Exercise Tolerance Decreased Hospitalization 28 Male 1/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Other Serious 12/11/2005 65 Female 1/12/2006 Consumer United Kingdom
Primary
Concomitant
Paranoia Other Serious 70 Male 211 lb 1/18/2006 Other Health Professional Canada
Primary
Concomitant
Ulcer Other Serious 12/11/2003 77 Female 159 lb 1/23/2006 Other Health Professional France
Primary
Secondary
Renal Cyst Hospitalization 2/14/2005 63 Male 185 lb 2/17/2006 Poland
Primary
Secondary
Concomitant
Injection Site Ulcer Other Serious 2/13/2006 51 Male 249 lb 3/2/2006 Other Health Professional Canada
Primary
Concomitant
Hypoglycaemia Hospitalization 2/1/2006 78 Female 2/28/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2004 78 Male 3/6/2006 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 1/22/2006 78 Male 3/7/2006
Primary
Secondary
Concomitant
Fall Hospitalization 1/22/2006 78 Male 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 2/15/2006 43 Female 3/7/2006
Primary
Secondary
Concomitant
Nausea Other Serious 11/14/2004 66 Female 3/1/2006 Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization Female 3/13/2006 Physician United Kingdom
Primary
Concomitant
Spinal Shock Hospitalization 2/2/2006 58 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Macular Oedema Disability 77 Male 175 lb 3/22/2006 Consumer United Kingdom
Primary
Concomitant
Spinal Shock Hospitalization 2/2/2006 58 Female 3/20/2006 United Kingdom
Primary
Concomitant
Pancreatitis Acute Life Threatening 3/7/2006 36 Male 287 lb 3/30/2006 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 3/7/2003 Female 126 lb 4/3/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2005 83 Female 3/30/2006 Pharmacist Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/7/2006 Other Health Professional Canada
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2006 83 Female 4/4/2006 Pharmacist Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2004 78 Male 4/21/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/27/2006 Other Health Professional Canada
Primary
Concomitant
Renal Cyst Hospitalization 2/14/2005 63 Male 185 lb 4/25/2006 Poland
Primary
Secondary
Concomitant
Myocardial Infarction Death 87 Male 5/3/2006 Pharmacist Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/3/2006 Pharmacist Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/5/2006 Consumer Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/5/2006 Consumer Canada
Primary
Concomitant
Pancytopenia Other Serious 2/24/2006 64 Female 5/9/2006 Physician Spain
Primary
Concomitant
Arthralgia Other Serious 4/3/2006 49 Female 181 lb 5/11/2006 Consumer United Kingdom
Primary
Concomitant
Retinitis Pigmentosa Other Serious 55 Female 5/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Other Serious 5/31/2005 70 Male 150 lb 5/23/2006 Other Health Professional Canada
Primary
Concomitant
Hemiplegia Other Serious 4/4/2006 54 Male 5/23/2006 Other Health Professional Egypt
Primary
Concomitant
Vomiting Other Serious 3/1/2006 56 Female 150 lb 5/19/2006 United Kingdom
Primary
Concomitant
Lethargy Other Serious 4/24/2006 72 Male 6/1/2006 Consumer United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 1/14/2005 64 Female 176 lb 5/25/2006 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 83 Male 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 71 Male 6/7/2006 Physician Australia
Primary
Concomitant
Pancreatic Carcinoma Other Serious 7/1/2004 Male 6/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 54 Male 6/8/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Urosepsis Hospitalization 54 Male 6/13/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 1/24/2006 Male 153 lb 6/27/2006 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 11/1/2005 71 Male 187 lb 7/5/2006 Physician Australia
Primary
Concomitant
Hepatitis Acute Other Serious 6/5/2006 71 Male 6/29/2006 Other Health Professional Italy
Primary
Concomitant
Vascular Bypass Graft Life Threatening 6/7/2006 62 Female 7/12/2006 Pharmacist Canada
Primary
Concomitant
Renal Failure Acute Life Threatening 1/1/2006 69 Female 132 lb 7/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vascular Bypass Graft Life Threatening 6/7/2006 62 Female 7/17/2006 Pharmacist Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 1/30/2006 69 Female 132 lb 7/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 92 Female 7/17/2006 United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 65 Male 7/24/2006 Physician Netherlands
Primary
Concomitant
Walking Disability Hospitalization 5/1/2006 74 Female 7/3/2006 Pharmacist United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 4/20/2006 52 Female 7/25/2006 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Acute Required Intervention 1/30/2006 7/19/2006 United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 5/30/2006 38 Male 287 lb 7/26/2006 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Required Intervention 1/30/2006 69 Female 132 lb 7/20/2006 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/1/2005 70 Male 179 lb 7/20/2006 Physician South Africa
Primary
Concomitant
Uterine Disorder Hospitalization 63 Female 7/27/2006 Korea, Republic Of
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 6/3/2006 81 Female 7/28/2006 United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 65 Male 8/8/2006 Physician New Zealand
Primary
Secondary
Pharmaceutical Product Complaint Other Serious 71 Female 8/18/2006 Denmark
Primary
Concomitant
Treatment Noncompliance Other Serious 6/15/2006 73 Female 165 lb 8/18/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Life Threatening 7/4/2006 73 Female 8/16/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 73 Female 8/23/2006 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 36 Male 287 lb 9/11/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Death 8/18/2006 71 Female 9/20/2006 Physician Thailand
Primary
Concomitant
Renal Failure Acute Hospitalization 3/14/2006 62 Female 9/21/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/8/2006 71 Female 9/25/2006 Physician Thailand
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/1/2006 74 Male 10/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 10/16/2006 50 Male 176 lb 11/10/2006 Physician South Africa
Primary
Concomitant
Metabolic Acidosis Life Threatening 9/21/2006 71 Female 165 lb 11/6/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/11/2004 46 Female 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Stage Iii Other Serious 8/31/2006 Female 150 lb 11/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Bladder Cancer Life Threatening 8/20/2005 67 Male 258 lb 11/16/2006 Consumer United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 11/1/2006 37 Female 11/18/2006 Pharmacist Australia
Primary
Concomitant
Periarthritis Other Serious 11/26/2003 57 Female 11/27/2006 Physician South Africa
Primary
Concomitant
Lichen Planus Disability 7/1/2006 68 Male 147 lb 11/29/2006 Consumer United Kingdom
Primary
Concomitant
Lichen Planus Disability 7/1/2006 68 Male 147 lb 11/29/2006 Consumer United Kingdom
Primary
Concomitant
Malaise Hospitalization 5/28/2006 94 Female 11/21/2006 Physician France
Primary
Secondary
Concomitant
Weight Increased Disability 5/1/2006 56 Male 12/4/2006 United Kingdom
Primary
Concomitant
Vasculitis Other Serious 5/31/2005 70 Male 150 lb 12/13/2006 Other Health Professional Canada
Primary
Concomitant
Cardiac Hypertrophy Death 11/15/2006 51 Female 252 lb 12/11/2006 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious Female 12/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Pacemaker Insertion Other Serious 61 Male 12/28/2006 United Kingdom
Primary
Concomitant
Skin Haemorrhage Other Serious 1/1/2003 65 Female 1/19/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Oedema Life Threatening 6/16/2006 61 Male 1/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vasculitis Other Serious 5/31/2005 70 Male 150 lb 2/26/2007 Other Health Professional Canada
Primary
Concomitant
Cardiac Pacemaker Insertion Other Serious Male 3/5/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 12/12/2006 46 Male 3/23/2007 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 182 lb 3/29/2007 Pharmacist United Kingdom
Primary
Concomitant
Pain In Jaw Other Serious 3/3/2007 Female 3/30/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/7/2007 Male 170 lb 4/5/2007 Malaysia
Primary
Concomitant
Pain In Jaw Other Serious 3/3/2007 Female 4/12/2007 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Acute Other Serious 9/1/2006 Male 187 lb 4/12/2007 Physician France
Primary
Secondary
Concomitant
Death Death 3/20/2007 50 Male 161 lb 4/13/2007 Physician Singapore
Primary
Concomitant
Vomiting Other Serious 3/2/2007 80 Female 115 lb 4/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 3/1/2007 Male 4/11/2007 United Kingdom
Primary
Concomitant
Irritability Other Serious 4/1/2006 71 Male 231 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 6/1/2007 6/22/2007 Physician Singapore
Primary
Concomitant
Jaundice Hospitalization Male 7/3/2007 Physician France
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 6/1/2007 7/11/2007 Physician Singapore
Primary
Concomitant
Swollen Tongue Life Threatening 6/12/2007 79 Female 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 8/14/2006 67 Male 10/9/2007 United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 10/9/2007 United Kingdom
Primary
Concomitant
Mood Altered Other Serious 8/28/2007 58 Male 179 lb 10/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Congestive Death 10/8/2007 50 Male 10/22/2007 Physician Russian Federation
Primary
Concomitant
Hypersensitivity Hospitalization 8/7/2007 57 Male 257 lb 10/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/1/2005 77 Female 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 10/24/2007 40 Male 11/2/2007 Physician United Kingdom
Primary
Concomitant
Hepatitis Other Serious 9/24/2007 69 Female 172 lb 11/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis Other Serious 9/24/2007 69 Female 172 lb 11/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 68 Male 209 lb 12/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Acute Promyelocytic Leukaemia Hospitalization 9/1/2004 54 Male 262 lb 12/26/2007 Pharmacist United Kingdom
Primary
Concomitant
Haematemesis Hospitalization 5/28/2006 Male 12/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 73 Male 1/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urine Output Decreased Other Serious 11/13/2004 84 Male 165 lb 1/19/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/1/2007 75 Female 176 lb 3/11/2008 Consumer Australia
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 2/1/2008 68 Male 3/17/2008 Physician Malaysia
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 2/1/2008 84 Female 3/21/2008 Physician Malaysia
Primary
Concomitant
Somnolence Other Serious 2/5/2008 Female 229 lb 3/24/2008 Physician France
Primary
Concomitant
Nausea Other Serious 65 Male 4/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Depression Hospitalization 1/1/2007 44 Male 280 lb 5/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Uterine Cervix Stenosis Other Serious 11/1/2007 60 Female 6/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/7/2007 66 Male 170 lb 6/9/2008 United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 50 Male 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 48 Male 6/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious Female 215 lb 6/19/2008 Consumer United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 6/1/2007 Female 6/27/2008 Physician Singapore
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/29/2008 71 Female 7/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 5/8/2008 51 Female 7/7/2008 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 5/29/2008 71 Female 7/7/2008 United Kingdom
Primary
Secondary
Concomitant
Eczema Hospitalization 4/18/2008 77 Female 8/8/2008 Other Health Professional France
Primary
Concomitant
Sudden Death Death 5/8/2008 51 Female 8/13/2008 Physician Canada
Primary
Concomitant
Throat Cancer Other Serious 1/18/2008 Male 181 lb 8/22/2008 United Kingdom
Primary
Concomitant
Syncope Hospitalization 6/6/2008 77 Male 180 lb 8/25/2008 United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2008 72 Male 198 lb 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cardiomyopathy Life Threatening 4/1/2007 Male 229 lb 9/12/2008 Consumer United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 8/18/2008 73 Female 9/12/2008 Consumer United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 8/18/2008 9/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Death 81 Male 9/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cataract Disability 1/1/2008 80 Male 9/24/2008 Consumer Portugal
Primary
Concomitant
Sinus Tachycardia Other Serious 8/18/2008 73 Female 9/29/2008
Primary
Concomitant
Suicidal Ideation Other Serious 10/14/2008 Male 10/22/2008 Consumer United Kingdom
Primary
Concomitant
Intentional Overdose Hospitalization 10/4/2008 Male 245 lb 10/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data