Gliclazide combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sudden Death Death 6/8/2001 Male 1/3/2006 Australia
Primary
Concomitant
Pain Hospitalization 11/8/2000 Female 1/3/2006 France
Primary
Concomitant
Urinary Retention Hospitalization 8/10/2000 Male 1/3/2006 France
Primary
Concomitant
Tendon Rupture Hospitalization 1/25/2002 Male 1/4/2006 France
Primary
Concomitant
Chest Pain Hospitalization 3/25/2001 Male 1/4/2006 Australia
Primary
Concomitant
Sleep Disorder Hospitalization 8/12/2002 Female 1/4/2006 Australia
Primary
Concomitant
Tendon Disorder Hospitalization 2/15/2002 Male 1/4/2006 France
Primary
Concomitant
Parotitis Hospitalization 7/13/2001 Male 1/4/2006 Australia
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/22/2002 Male 1/4/2006 Australia
Primary
Concomitant
Pituitary Tumour Benign Hospitalization 12/13/2001 Female 1/4/2006 Australia
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 2/12/2002 Male 1/4/2006 Australia
Primary
Concomitant
Aortic Aneurysm Rupture Death 11/21/2003 Male 1/4/2006 France
Primary
Concomitant
Bone Marrow Failure Other Serious 9/13/2004 Male 1/4/2006 Australia
Primary
Concomitant
Bladder Cancer Other Serious 8/25/2004 Female 1/4/2006 Australia
Primary
Concomitant
Facial Palsy Hospitalization 2/13/2006 Female 152 lb 3/3/2006 Greece
Primary
Concomitant
Syncope Vasovagal Other Serious 11/12/2005 64 Male 3/1/2006 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Haematemesis Hospitalization 2/6/2006 60 Male 3/16/2006 Consumer United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 1/1/2006 60 Male 3/16/2006 Consumer Ireland
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/23/2005 58 Female 3/22/2006 Other Health Professional France
Primary
Concomitant
Hypoglycaemia Hospitalization 2/9/2006 80 Male 3/14/2006 United Kingdom
Primary
Secondary
Concomitant
Facial Palsy Hospitalization 2/13/2006 Female 152 lb 3/22/2006 Greece
Primary
Concomitant
Metastatic Gastric Cancer Hospitalization 2/19/2006 60 Male 3/23/2006 Consumer United States
Primary
Secondary
Concomitant
Facial Palsy Hospitalization 2/13/2006 Female 152 lb 3/30/2006 Greece
Primary
Concomitant
Toxic Skin Eruption Hospitalization 11/23/2005 58 Female 4/7/2006 Other Health Professional France
Primary
Concomitant
Facial Palsy Hospitalization 2/13/2006 Female 152 lb 4/13/2006 Greece
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 4/24/2006 Consumer Ireland
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 1/1/2006 60 Male 5/2/2006 Consumer Ireland
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/15/2006 66 5/9/2006 Other Health Professional France
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/5/2006 80 Female 5/25/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 6/3/2006 81 Female 7/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Scrotal Pain Hospitalization 7/1/2006 68 Male 8/18/2006 Other Health Professional Hungary
Primary
Concomitant
Vomiting Life Threatening 7/4/2006 73 Female 8/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/30/2006 69 Female 8/21/2006 Denmark
Primary
Concomitant
Hypoglycaemia Other Serious 6/3/2006 81 Female 8/21/2006 United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 6/26/2006 71 Male 9/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 9/6/2004 Male 214 lb 9/7/2006 Australia
Primary
Concomitant
Weight Decreased Other Serious 3/12/2006 80 Female 9/19/2006 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/19/2006 59 Male 10/27/2006 Other Health Professional Japan
Primary
Concomitant
Metabolic Acidosis Required Intervention 9/21/2006 71 Female 11/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 5/6/2005 60 Female 11/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 10/21/2006 69 Male 12/12/2006 Korea, Republic Of
Primary
Concomitant
Pneumonia Hospitalization 3/15/2002 Male 12/22/2006 Other Health Professional
Primary
Concomitant
Pneumonia Hospitalization 3/15/2002 Male 12/28/2006 Other Health Professional
Primary
Concomitant
Pyrexia Other Serious 7/19/2006 59 Male 1/2/2007 Other Health Professional Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 58 Female 280 lb 1/25/2007 Other Health Professional Poland
Primary
Concomitant
Palpitations Other Serious 1/12/2007 52 Male 205 lb 2/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Disability 7/19/2006 59 Male 3/27/2007 Other Health Professional Japan
Primary
Concomitant
Vomiting Life Threatening 60 Female 8/29/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Insomnia Other Serious 4/23/2004 59 Male 10/1/2007 China
Primary
Concomitant
Vasculitic Rash Other Serious 8/31/2007 73 Male 10/12/2007 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 80 Male 11/5/2007 Physician Malaysia
Primary
Concomitant
Renal Impairment Other Serious 59 Male 11/1/2007 United Kingdom
Primary
Concomitant
Pallor Life Threatening 9/19/2007 69 Male 11/6/2007 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2006 83 Male 11/20/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Interacting
Aspartate Aminotransferase Increased Other Serious 5/19/2006 73 Male 280 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cardiovascular Disorder Hospitalization 10/15/2007 66 Female 11/21/2007 Physician Russian Federation
Primary
Concomitant
Palpitations Other Serious 10/1/2007 57 Female 271 lb 11/30/2007 Consumer United Kingdom
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 7/1/2007 61 Female 12/28/2007
Primary
Concomitant
Blood Urea Increased Hospitalization 1/1/2007 46 Female 1/18/2008 Physician Malaysia
Primary
Concomitant
Cholestasis Hospitalization 10/1/2007 78 Female 1/31/2008 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/16/2007 75 Male 2/15/2008 Physician Australia
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 70 Female 154 lb 3/1/2008 United Kingdom
Primary
Concomitant
Urine Output Decreased Other Serious 70 Female 154 lb 3/9/2008 United Kingdom
Primary
Concomitant
Nausea Other Serious 3/26/2008 63 Female 184 lb 5/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Hospitalization 45 Male 5/14/2008 Physician Malaysia
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 11/13/2007 60 Male 231 lb 7/30/2008 Physician Switzerland
Primary
Concomitant
Vision Blurred Other Serious 7/5/2008 Male 249 lb 8/15/2008 Physician United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 11/13/2007 60 Male 231 lb 8/27/2008 Physician Switzerland
Primary
Concomitant
Vitamin B12 Decreased Other Serious 70 9/12/2008 Physician United Kingdom
Primary
Concomitant
Liver Disorder Other Serious 5/28/2008 80 Female 10/1/2008 Other Health Professional Spain
Primary
Concomitant
Diarrhoea Hospitalization 78 Male 10/10/2008 United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 1/1/2008 61 Male 10/20/2008 Pharmacist Australia
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/1/2008 Male 10/18/2008 Physician Italy
Primary
Concomitant
Gastrostomy Tube Insertion Hospitalization 1/1/2006 Male 10/21/2008 Physician Finland
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/16/2008 Male 225 lb 10/21/2008 United Kingdom
Primary
Concomitant
Venous Oxygen Saturation Increased Other Serious 4/15/2006 66 10/22/2008 Denmark
Primary
Concomitant
Hypoglycaemia Other Serious 6/3/2006 81 Female 10/22/2008 United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 6/1/2006 54 Male 10/22/2008 United Kingdom
Primary
Concomitant
Renal Failure Chronic Other Serious 1/30/2006 69 Female 10/22/2008 Denmark
Primary
Concomitant
Swelling Face Life Threatening 8/6/2008 55 Female 10/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Blood Glucose Increased Other Serious 9/1/2008 57 Male 214 lb 11/17/2008 Pharmacist Australia
Primary
Concomitant
Intentional Drug Misuse Hospitalization 89 Female 11/21/2008 Physician Australia
Primary
Concomitant
Vasculitis Hospitalization 10/1/2008 55 Female 11/24/2008 Physician France
Primary
Concomitant
Intussusception Life Threatening 87 Female 12/3/2008 Physician Australia
Primary
Concomitant
Toxic Skin Eruption Hospitalization 10/1/2008 55 Female 12/19/2008 Physician France
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 11/1/2008 61 Male 187 lb 1/26/2009 Other Health Professional Australia
Primary
Concomitant
Vomiting Hospitalization 69 Female 1/21/2009 Other Health Professional Netherlands
Primary
Concomitant
Retching Other Serious 72 Female 150 lb 1/29/2009 Consumer Brazil
Primary
Concomitant
Dyspepsia Hospitalization 10/27/2008 2/18/2009 Physician United Kingdom
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 2/22/2008 3/9/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/10/2008 4/8/2009 Other Health Professional Netherlands
Primary
Concomitant
Renal Failure Other Serious 3/10/2008 Female 287 lb 4/20/2009 Other Health Professional Netherlands
Primary
Concomitant
Hypertension Other Serious 4/16/2009 4/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 65 Male 4/30/2009 Malaysia
Primary
Concomitant
Hypertension Other Serious 4/16/2009 5/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 10/1/2008 55 Female 5/12/2009 Physician France
Primary
Concomitant
Rash Papular 10/16/2008 55 Female 234 lb 5/21/2009 Other Health Professional France
Primary
Concomitant
Infection Other Serious 2/14/2009 50 Male 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 10/16/2008 55 Female 234 lb 5/27/2009 Physician France
Primary
Concomitant
Blister Other Serious 2/14/2009 50 Male 119 lb 5/29/2009 United States
Primary
Concomitant
Palpitations Other Serious 1/30/2009 61 Female 93 lb 6/5/2009 Other Health Professional Thailand
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 83 Male 6/5/2009 Taiwan, Province Of China
Primary
Concomitant
Interacting
Tibia Fracture Hospitalization 7/31/2007 Male 190 lb 6/8/2009 Physician United Kingdom
Primary
Concomitant
Hypertension Other Serious 4/16/2009 74 6/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 10/9/2008 Male 6/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Shock Death 10/2/2008 61 Female 6/12/2009
Primary
Secondary
Concomitant
Palpitations Other Serious 5/12/2009 73 Female 6/12/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/17/2008 185 lb 6/15/2009 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/9/2009 Male 261 lb 6/12/2009 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 4/16/2009 74 6/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/16/2009 72 Female 192 lb 8/19/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 50 Male 8/20/2009 United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 7/16/2009 Female 192 lb 8/28/2009 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 12/15/2008 Female 9/3/2009 Consumer Australia
Primary
Secondary
Concomitant
Pancreas Infection Other Serious 8/5/2009 72 9/14/2009 Other Health Professional Portugal
Primary
Concomitant
Skin Ulcer Hospitalization 1/1/2009 Male 10/8/2009 Physician Canada
Primary
Concomitant
Urticaria Other Serious 5/1/2009 Female 346 lb 10/13/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 10/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Pancreas Infection Other Serious 8/5/2009 72 10/27/2009 Other Health Professional Portugal
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 11/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/1/2007 59 Male 11/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 12/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 10/27/2008 68 Female 12/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cytolytic Hepatitis Life Threatening 8/1/2009 59 Male 12/17/2009 Physician Belgium
Primary
Concomitant
Swelling Face Other Serious 12/17/2008 75 Male 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/1/2009 52 Female 240 lb 1/12/2010 Consumer Canada
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 12/30/2009 1/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/15/2008 70 Female 154 lb 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Dehydration Hospitalization 1/8/2010 68 Male 267 lb 2/1/2010 Other Health Professional Canada
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/3/2009 64 Male 2/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 12/21/2008 75 Male 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Impaired Gastric Emptying Other Serious 11/24/2009 54 Female 2/3/2010 Physician Russian Federation
Primary
Concomitant
Anaemia Hospitalization 12/15/2009 Female 150 lb 2/4/2010 Physician Poland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/21/2004 86 Male 1/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening Male 2/12/2010 Other Health Professional Australia
Primary
Secondary
Oedema Peripheral Other Serious 1/6/2010 60 Male 209 lb 2/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 1/6/2010 60 Male 209 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Hospitalization 12/15/2009 Female 150 lb 2/16/2010 Physician Poland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/3/2009 64 Male 2/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/1/2010 77 Female 2/17/2010 Consumer Canada
Primary
Concomitant
Vomiting Required Intervention 10/1/2007 73 Male 2/15/2010 Physician Hong Kong
Primary
Concomitant
Skin Haemorrhage Other Serious 69 Female 163 lb 2/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 4/16/2009 74 Female 198 lb 3/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypomagnesaemia Hospitalization 12/30/2009 3/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 52 Female 240 lb 3/10/2010 Consumer Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 3/11/2010 Other Health Professional France
Primary
Secondary
Concomitant
Dysarthria Other Serious 63 Female 3/17/2010 Consumer Malaysia
Primary
Concomitant

Drug Data