Gliclazide (Gliclazide) combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Other Serious 6/1/2005 60 Male 12/30/2005 Physician Netherlands
Primary
Concomitant
Melaena Hospitalization 12/11/2003 77 Female 1/24/2006 Other Health Professional France
Primary
Secondary
Blood Triglycerides Increased Life Threatening 10/17/2005 46 Male 280 lb 1/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 10/17/2005 46 Male 280 lb 2/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Hospitalization 10/1/2005 55 Male 198 lb 2/10/2006 Physician France
Primary
Concomitant
Subdural Haemorrhage Hospitalization 8/1/2005 58 Male 160 lb 2/14/2006 Physician South Africa
Primary
Concomitant
Subdural Haemorrhage Hospitalization 8/1/2005 58 Male 160 lb 2/24/2006 Physician South Africa
Primary
Concomitant
Fall Hospitalization 1/22/2006 78 Male 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 66 Male 3/13/2006 United Kingdom
Primary
Concomitant
Weight Decreased Required Intervention 1/14/2005 79 Female 123 lb 3/21/2006 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 1/14/2005 79 Female 123 lb 3/29/2006 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 1/14/2005 79 Female 123 lb 4/3/2006 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 1/14/2005 79 Female 123 lb 4/20/2006 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/15/2006 66 176 lb 5/15/2006 United Kingdom
Primary
Concomitant
Weight Decreased Required Intervention 1/14/2005 79 Female 123 lb 6/8/2006 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/30/2006 69 Female 132 lb 7/20/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 9/11/2006 Brazil
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 1/14/2005 79 Female 123 lb 9/6/2006 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/14/2005 79 Female 123 lb 9/18/2006 Physician Australia
Primary
Secondary
Concomitant
Oedema Life Threatening 6/16/2006 Male 9/29/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 10/11/2006 Brazil
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 7/4/2006 80 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Granulocytopenia Hospitalization 11/23/2004 63 Male 179 lb 10/17/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/1/2006 74 Male 10/19/2006 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 70 Male 10/20/2006 Brazil
Primary
Secondary
Concomitant
Lichen Planus Disability 7/1/2006 68 Male 147 lb 10/24/2006 United Kingdom
Primary
Concomitant
Melaena Hospitalization 9/24/2006 69 Female 10/26/2006 United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Other Serious 6/19/2006 70 Male 161 lb 10/27/2006 Other Health Professional Australia
Primary
Concomitant
Lichen Planus Other Serious 7/1/2006 68 Male 147 lb 10/30/2006 United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 9/11/2006 74 Female 212 lb 10/31/2006 Physician United Kingdom
Primary
Concomitant
Myalgia Disability 7/1/2006 73 Female 11/3/2006 Pharmacist United Kingdom
Primary
Concomitant
Metabolic Acidosis Life Threatening 9/21/2006 71 Female 165 lb 11/9/2006 United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/8/2006 United Kingdom
Primary
Secondary
Concomitant
Swelling Life Threatening 6/16/2006 Male 12/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 1/14/2005 79 Female 123 lb 12/20/2006 Physician Australia
Primary
Secondary
Concomitant
Idiosyncratic Drug Reaction Other Serious 52 Male 116 lb 1/31/2007 United Kingdom
Primary
Secondary
Concomitant
Eosinophilic Pustular Folliculitis Hospitalization 71 Male 3/12/2007 Physician Australia
Primary
Concomitant
Joint Swelling Other Serious 11/1/2006 61 Female 269 lb 3/23/2007 United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/14/2007 77 Male 154 lb 3/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Required Intervention 11/1/2006 61 Female 3/26/2007 United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 8/15/2006 56 Female 137 lb 3/29/2007 Physician United Kingdom
Primary
Concomitant
Post Inflammatory Pigmentation Change Other Serious 71 Male 4/25/2007 Other Health Professional Australia
Primary
Concomitant
Visual Disturbance Other Serious 3/27/2007 71 Female 5/7/2007 United Kingdom
Primary
Concomitant
Humerus Fracture Hospitalization 4/15/2007 70 Female 5/8/2007 United Kingdom
Primary
Concomitant
Convulsion Hospitalization 1/18/2007 57 Female 5/22/2007 United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 80 Female 7/25/2007 United Kingdom
Primary
Concomitant
Renal Failure Other Serious 2/18/2006 60 NotSpecified 9/15/2007 Australia
Primary
Secondary
Visual Disturbance Other Serious 80 Female 9/28/2007 United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 75 Female 10/6/2007 United Kingdom
Primary
Concomitant
Vasculitic Rash Other Serious 8/31/2007 73 Male 10/15/2007 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 3/1/2007 59 Male 10/30/2007 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 9/15/2007 Female 11/13/2007 United Kingdom
Primary
Secondary
Concomitant
Self-medication Required Intervention 83 Male 11/14/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/1/2006 83 Male 11/17/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/15/2007 Female 11/22/2007 United Kingdom
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Life Threatening 10/25/2007 73 Male 11/28/2007 United Kingdom
Primary
Concomitant
Swelling Face Other Serious 73 Male 1/15/2008 United Kingdom
Primary
Concomitant
Pneumonia Death 1/26/2008 76 2/26/2008 Physician United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 8/9/2007 United Kingdom
Primary
Secondary
Concomitant
Depression Hospitalization 1/1/2007 44 Male 280 lb 5/20/2008 United Kingdom
Primary
Concomitant
Renal Failure Other Serious 3/20/2008 70 Female 176 lb 5/22/2008 Physician United Kingdom
Primary
Concomitant
Uterine Cervix Stenosis Other Serious 11/1/2007 60 Female 6/11/2008 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 69 Female 6/12/2008 Other Health Professional Netherlands
Primary
Concomitant
Weight Decreased Other Serious 5/29/2008 71 Female 7/2/2008 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 50 Male 7/4/2008 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 50 Male 7/4/2008 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 50 Male 7/10/2008 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 61 Male 8/12/2008 Australia
Primary
Concomitant
Hypoglycaemia Other Serious 8/22/2008 France
Primary
Secondary
Somnolence Other Serious 61 Male 8/21/2008 Australia
Primary
Concomitant
Angioedema Other Serious 70 Female 9/5/2008 United Kingdom
Primary
Concomitant
Rhabdomyolysis Death 81 Male 9/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 61 Male 9/18/2008 Consumer Australia
Primary
Concomitant
Swelling Face Other Serious 8/18/2008 63 Female 12/3/2008 Philippines
Primary
Secondary
Concomitant
Obesity Other Serious 42 Male 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Melaena Hospitalization 12/11/2003 77 Female 12/12/2008 France
Primary
Secondary
Microcytic Anaemia Other Serious 4/1/2008 73 Female 12/23/2008 United Kingdom
Primary
Concomitant
Hypochromic Anaemia Other Serious 4/1/2008 73 Female 1/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 75 Male 1/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/11/2008 80 Female 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Obesity Other Serious 42 Male 1/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Swelling Face Other Serious 12/24/2008 75 Male 2/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 43 Male 2/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 2/11/2009 United Kingdom
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 10/27/2008 68 Female 2/18/2009 United Kingdom
Primary
Concomitant
Blister Infected Other Serious 2/14/2009 50 Male 118 lb 3/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Other Serious 12/1/2008 60 Male 4/3/2009 United Kingdom
Primary
Concomitant
Infection Other Serious 50 Male 4/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 43 Male 4/7/2009 United Kingdom
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 3/10/2009 76 Female 4/24/2009 United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Required Intervention Male United Kingdom
Primary
Concomitant
Anaemia Hospitalization 3/4/2009 61 Male 5/6/2009 Physician Poland
Primary
Secondary
Concomitant
Dermatitis Bullous Other Serious 2/14/2009 50 Male 118 lb 5/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
No Adverse Event Other Serious 64 Male 6/5/2009 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 73 Male 6/15/2009 Hong Kong
Primary
Concomitant
Myalgia Disability 5/9/2009 74 Male 248 lb 6/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 5/11/2009 76 Male 6/18/2009 Consumer United Kingdom
Primary
Concomitant
Atrioventricular Block Complete Other Serious 6/5/2009 61 Male 6/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Other Serious Female 7/1/2009 Australia
Primary
Concomitant
Bradycardia Other Serious 6/5/2009 61 Male 7/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 6/13/2009 66 7/14/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 62 Female 8/8/2009 Netherlands
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 3/21/2008 79 Male 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/13/2009 66 9/25/2009 Physician United Kingdom
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 1/18/2007 57 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 9/3/2009 60 Female 11/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 9/3/2009 60 Female 12/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/12/2010 69 Female 107 lb 3/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Constipation Disability 10/17/2009 74 Male 3/22/2010 United Kingdom
Primary
Concomitant
Migraine Other Serious 2/26/2010 59 4/5/2010 United Kingdom
Primary
Concomitant
Pneumonia Other Serious 60 Male 4/2/2010 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 60 Male 4/12/2010 Physician United Kingdom
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Life Threatening 80 Male 4/10/2010 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 60 Male 4/22/2010 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 60 Male 5/3/2010 United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 2/23/2008 60 Female 5/13/2010 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 60 Male 5/31/2010 United Kingdom
Primary
Secondary
Concomitant
Pancreatic Carcinoma Hospitalization 3/4/2009 61 Male 165 lb 7/16/2010 Physician Poland
Primary
Secondary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/16/2010 United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 9/20/2010 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2010 69 Male 10/4/2010 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2010 69 Male 10/7/2010 United Kingdom
Primary
Concomitant
Acute Myocardial Infarction Required Intervention 9/30/2008 83 Female 10/19/2010 United Kingdom
Primary
Concomitant
Renal Tubular Acidosis Life Threatening 88 Male 11/3/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Acidosis Life Threatening 9/7/2010 88 Male 163 lb 11/6/2010 United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 62 Male 11/15/2010 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 63 Male 271 lb 11/23/2010 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 63 Male 271 lb 11/23/2010 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 66 Male 12/9/2010 Other Health Professional Hungary
Primary
Secondary
Concomitant
Skin Lesion Other Serious 3/1/2010 73 Male 5/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Upper Limb Fracture Required Intervention Female 5/31/2011 United Kingdom
Primary
Concomitant
Infusion Site Necrosis Hospitalization 3/1/2010 73 Male 6/8/2011 United Kingdom
Primary
Concomitant
Blister Hospitalization 11/1/2009 60 Female 6/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Idiopathic Pulmonary Fibrosis Other Serious Male 6/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Urticaria Other Serious 5/11/2011 60 Female 6/22/2011 Other Health Professional Italy
Primary
Concomitant
Erythema Other Serious 69 6/24/2011 Other Health Professional
Primary
Secondary
Concomitant
Coma Other Serious 1/1/2009 71 7/8/2011 Other Health Professional
Primary
Secondary
Pleural Effusion Hospitalization 5/3/2005 36 Male 7/11/2011 United Kingdom
Primary
Concomitant
Diabetes Mellitus Other Serious 39 Female 7/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Back Pain Disability 6/24/2011 67 Female 7/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/22/2008 75 Male 8/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bladder Cancer Life Threatening 5/1/2010 62 Male 8/4/2011 United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 11/13/2007 43 Male 8/5/2011 Other Health Professional
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/13/2007 Male 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bedridden Disability 7/22/2011 75 Male 8/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bladder Cancer Death 66 Male 8/23/2011 United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 8/18/2011 65 Male 9/2/2011 Physician United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 1/26/2011 67 Male 9/13/2011 United Kingdom
Primary
Concomitant

Drug Data