Glibenclamide combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Hospitalization 12/10/1999 Male 1/4/2006 France
Primary
Concomitant
Pleural Effusion Hospitalization 9/11/2001 Male 1/4/2006 France
Primary
Concomitant
Pituitary Tumour Benign Hospitalization 12/13/2001 Female 1/4/2006 Australia
Primary
Concomitant
Skin Graft Infection Other Serious 9/15/2005 Male 192 lb 1/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Disorder Other Serious 9/21/2005 57 Male 216 lb 1/10/2006 Netherlands
Primary
Secondary
Concomitant
Blood Creatinine Increased 2/16/2005 69 218 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased 2/16/2005 69 218 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 1/17/2006 United States
Primary
Concomitant
Pleural Disorder Other Serious 9/21/2005 57 Male 216 lb 1/10/2006 Netherlands
Primary
Secondary
Concomitant
Pulmonary Hypertension Death 10/19/2005 Male 1/31/2006 United States
Primary
Concomitant
Septic Shock Death 71 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 6/1/2005 Male 263 lb 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Localised Infection Other Serious 63 Male 150 lb 3/9/2006 Physician Mexico
Primary
Concomitant
Catheter Related Complication Other Serious 3/3/2004 62 Male 209 lb 3/14/2006 Consumer Germany
Primary
Concomitant
Sputum Abnormal Hospitalization 3/5/2006 61 Female 3/27/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 1/1/2004 71 Female 3/28/2006 Physician Czech Republic
Primary
Concomitant
Myocardial Infarction Hospitalization 6/29/2003 Male 165 lb 4/14/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Urinary Tract Infection Death 1/25/2006 72 Female 150 lb 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Surgical Procedure Repeated Hospitalization 61 Male 4/28/2006 Physician Czech Republic
Primary
Concomitant
Tachycardia Other Serious 5/8/2006 58 Female 143 lb 5/16/2006 Consumer Brazil
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/5/2006 61 Female 5/22/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 5/6/2006 61 Male 148 lb 5/31/2006 Physician Brazil
Primary
Concomitant
Rash Hospitalization 5/15/2006 70 Male 6/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dizziness Hospitalization 2/23/2006 75 Male 7/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/6/2006 61 Male 148 lb 7/5/2006 Physician Brazil
Primary
Concomitant
Somnolence Hospitalization 6/28/2006 66 Female 7/14/2006 Physician Thailand
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Femur Fracture Other Serious 3/25/2006 Male 168 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 65 Male 136 lb 9/1/2006 Physician Singapore
Primary
Concomitant
Weight Increased Other Serious 10/20/2006 Male 231 lb 2/19/2007 Pharmacist France
Primary
Concomitant
Orthopnoea Life Threatening 1/1/2006 80 Male 209 lb 2/26/2007 Physician United Kingdom
Primary
Concomitant
Tuberculosis Hospitalization 6/25/2007 67 Male 7/4/2007 Physician Guatemala
Primary
Concomitant
Femur Fracture Other Serious 6/15/2007 79 Female 110 lb 7/2/2007 Consumer Brazil
Primary
Concomitant
Renal Failure Acute Other Serious 61 Female 3/13/2008 Spain
Primary
Secondary
Vomiting Other Serious 61 Female 3/14/2008 Physician Spain
Primary
Secondary
Concomitant
Viral Infection Hospitalization 11/1/2007 Female 325 lb 3/14/2008 Consumer United States
Primary
Concomitant
Vision Blurred 5/1/2007 Male 240 lb 3/15/2008 United States
Primary
Concomitant
Unresponsive To Stimuli Death 3/22/2006 48 Male 3/10/2008 Other Health Professional Singapore
Primary
Concomitant
Renal Failure Acute Other Serious 61 Female 3/18/2008 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Other Serious 68 Male 3/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/12/2008 61 Male 6/18/2008 Other Health Professional Canada
Primary
Secondary
Weight Decreased Hospitalization 6/10/2008 Female 6/26/2008 Consumer Colombia
Primary
Concomitant
Renal Failure Life Threatening 5/24/2008 Female 7/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/5/2008 70 Male 181 lb 7/16/2008 Mexico
Primary
Secondary
Concomitant
Blood Thyroid Stimulating Hormone Increased 6/1/2007 Female 351 lb 8/22/2008 Physician United States
Primary
Concomitant
Renal Mass Other Serious 11/26/2008 Female 12/24/2008 Consumer United Kingdom
Primary
Concomitant
Death Death 12/31/2008 Other Health Professional Colombia
Primary
Secondary
Concomitant
Predisposition To Disease Other Serious 1/21/2009 India
Primary
Secondary
Vomiting Hospitalization 1/25/2009 47 Female 2/2/2009 Consumer Colombia
Primary
Concomitant
Death Death 2/5/2009 Other Health Professional Colombia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 2/6/2009 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/14/2008 2/16/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 83 Female 2/20/2009 Switzerland
Primary
Secondary
Respiratory Acidosis Other Serious 2/20/2009 Switzerland
Primary
Secondary
Hypoglycaemia Death 2/20/2009 Switzerland
Primary
Secondary
Syncope Life Threatening 1/8/2009 Female 2/25/2009 Physician Switzerland
Primary
Concomitant
Lung Disorder Life Threatening 12/28/2008 Male 2/26/2009 Other Health Professional France
Primary
Concomitant
Respiratory Disorder Other Serious 1/15/2009 Female 2/26/2009 Consumer Mexico
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 47 Female 3/6/2009 Consumer Colombia
Primary
Concomitant
Pupils Unequal Hospitalization 2/27/2009 3/25/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2006 Female 187 lb 4/1/2009 Consumer Brazil
Primary
Secondary
Concomitant
Stomatitis Life Threatening 3/19/2009 4/8/2009 Physician Romania
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 3/20/2009 79 5/26/2009 Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 190 lb 6/9/2009 Physician Brazil
Primary
Secondary
Concomitant
Cervix Carcinoma Other Serious 3/19/2009 Female 6/22/2009 Physician Italy
Primary
Concomitant
Hyperglycaemia Other Serious 3/5/2005 Female 6/24/2009 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 4/24/2008 68 Female 7/18/2009 United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/1/2008 77 Female 209 lb 8/4/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Breast Cancer Other Serious 7/1/2008 62 Female 8/6/2009 Pharmacist South Africa
Primary
Concomitant
Vomiting Other Serious 5/1/2009 43 Female 8/14/2009 Physician Colombia
Primary
Concomitant
Blindness Transient Other Serious 59 Male 8/17/2009 Physician Mexico
Primary
Concomitant
Blood Glucose Increased Male 170 lb 8/21/2009 United States
Primary
Concomitant
Rash 8/25/2008 Female 8/21/2009 United States
Primary
Concomitant
Paraesthesia 9/25/2008 Female 239 lb 8/22/2009 United States
Primary
Concomitant
Myalgia 10/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Pruritus 9/19/2008 Male 8/22/2009 United States
Primary
Concomitant
Pain In Extremity 10/12/2008 Female 8/22/2009 United States
Primary
Secondary
Concomitant
Urticaria 10/26/2008 Female 8/22/2009 Consumer United States
Primary
Concomitant
Pruritus 8/1/2008 Male 8/22/2009 Other Health Professional United States
Primary
Concomitant
Pollakiuria Male 8/22/2009 United States
Primary
Concomitant
Feeling Abnormal Male 8/22/2009 United States
Primary
Concomitant
Hypercalcaemia Life Threatening 3/19/2009 71 9/11/2009 Physician Romania
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 10/8/2009 United States
Primary
Secondary
Urticaria Hospitalization 51 10/19/2009 Other Health Professional Israel
Primary
Concomitant
Toe Amputation Hospitalization 7/27/2009 63 Male 234 lb 10/20/2009 Consumer Brazil
Primary
Concomitant
Hypoglycaemia Hospitalization 9/30/2009 63 Male 234 lb 10/20/2009 Consumer Brazil
Primary
Secondary
Concomitant
Fracture Other Serious 10/20/2009 Canada
Primary
Secondary
Sudden Cardiac Death Other Serious 10/21/2009 Brazil
Primary
Secondary
Duodenal Ulcer Haemorrhage Hospitalization 10/10/2009 71 Male 148 lb 11/2/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 61 Male 11/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 10/1/2009 49 Male 172 lb 11/5/2009 Consumer Brazil
Primary
Concomitant
Lung Disorder Other Serious 11/6/2009 France
Primary
Secondary
Oedema Peripheral Other Serious 11/6/2009 France
Primary
Secondary
Duodenal Ulcer Haemorrhage Hospitalization 10/10/2009 71 Male 148 lb 11/16/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Paraesthesia Other Serious 10/1/2009 49 Male 172 lb 12/15/2009 Consumer Brazil
Primary
Concomitant
Hypertension Other Serious 64 Female 150 lb 12/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 68 Male 12/22/2009 United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2008 67 Male 1/13/2010 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2008 54 Male 1/13/2010 Physician United States
Primary
Secondary
Pneumonia Hospitalization 1/5/2010 Male 346 lb 2/16/2010 Physician Spain
Primary
Secondary
Concomitant
Swelling Other Serious Male 198 lb 3/5/2010 Brazil
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 5/1/2009 36 Female 190 lb 3/11/2010 Consumer Mexico
Primary
Concomitant
Somnolence Other Serious Female 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 4/18/2009 Female 208 lb 3/23/2010 Israel
Primary
Concomitant
Pupils Unequal Hospitalization 2/27/2009 72 Female 3/26/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/11/2010 81 Female 4/9/2010 Physician Argentina
Primary
Concomitant
Pneumonia Hospitalization 10/20/2009 69 Male 174 lb 4/26/2010 Physician Chile
Primary
Secondary
Concomitant
Pupils Unequal Hospitalization 2/27/2009 72 Female 4/26/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/1/2008 77 Female 5/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 7/1/2008 77 Female 5/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 7/1/2008 77 Female 5/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 7/1/2008 77 Female 5/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 7/1/2008 77 Female 5/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 7/1/2008 77 Female 209 lb 5/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 3/20/2009 79 Female 95 lb 5/12/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Linear Iga Disease Hospitalization 4/6/2010 87 Female 6/4/2010 Consumer Switzerland
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 3/1/2010 51 Female 6/3/2010 Brazil
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 6/21/2010 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 76 Female 7/19/2010 Other Health Professional Germany
Primary
Secondary
Retching Other Serious 51 Male 159 lb 7/23/2010 Consumer Brazil
Primary
Concomitant
Agitation Other Serious 51 Male 159 lb 8/5/2010 Consumer Brazil
Primary
Concomitant
Renal Failure Acute Other Serious 74 Female 8/10/2010 Consumer Spain
Primary
Secondary
Leg Amputation Other Serious 84 Female 9/8/2010 Consumer Guatemala
Primary
Concomitant
Chromaturia 7/5/2008 77 Male 9/9/2010 Other Health Professional United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/14/2010 49 Male 152 lb 9/10/2010 Physician Saudi Arabia
Primary
Concomitant
Tremor Hospitalization 7/11/2010 80 Female 9/16/2010 Consumer Colombia
Primary
Concomitant
Weight Decreased Other Serious 8/2/2010 45 Female 9/20/2010 Physician Argentina
Primary
Concomitant
Renal Failure Acute Life Threatening 5/12/2004 70 Male 9/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/3/2010 80 Male 152 lb 9/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/14/2010 49 Male 152 lb 9/27/2010 Physician Saudi Arabia
Primary
Concomitant
Road Traffic Accident Hospitalization 1/1/2010 52 Male 9/27/2010 Physician Colombia
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/14/2010 49 Male 152 lb 10/5/2010 Physician Saudi Arabia
Primary
Concomitant
Renal Impairment Other Serious 69 Male 10/7/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 6/3/2010 76 Male 132 lb 10/11/2010 Physician Germany
Primary
Concomitant
Respiratory Tract Infection Other Serious 75 Male 10/11/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Rales Other Serious 10/11/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/1/2010 73 Female 10/12/2010 Physician Italy
Primary
Concomitant
Hypoxic-ischaemic Encephalopathy Other Serious 9/15/2010 55 Female 10/21/2010 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/14/2010 49 Male 154 lb 10/22/2010 Physician Saudi Arabia
Primary
Concomitant
Septic Shock Hospitalization 1/1/2010 54 Male 346 lb 10/22/2010 Physician Spain
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 3/6/2008 66 Female 10/21/2010 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/2/2010 45 Female 10/25/2010 Physician Argentina
Primary
Concomitant
Sepsis Hospitalization 1/1/2010 73 Female 10/18/2010 Physician Italy
Primary
Concomitant
Sudden Death Death 9/2/2010 65 Female 175 lb 11/4/2010 Other Health Professional Colombia
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/14/2010 49 Male 154 lb 11/10/2010 Other Health Professional Saudi Arabia
Primary
Concomitant
Renal Failure Acute Other Serious 10/17/2010 Female 11/12/2010 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 7/1/2010 67 Male 11/17/2010 Pharmacist
Primary
Concomitant
Intentional Drug Misuse Other Serious 38 Male 11/17/2010 Physician Canada
Primary
Concomitant
Sepsis Other Serious 9/10/2010 75 Male 192 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant

Drug Data