Gilenya combined with Zanaflex

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 11/19/2010 39 Female 11/26/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 11/19/2010 39 Female 12/8/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/19/2010 39 Female 12/22/2010 United States
Primary
Concomitant
Kidney Infection Other Serious 12/23/2010 47 Female 1/4/2011 Consumer United States
Primary
Concomitant
Heart Rate Decreased Other Serious 12/28/2010 45 Female 1/27/2011 Other Health Professional United States
Primary
Concomitant
Cough Other Serious 12/23/2010 47 Female 2/9/2011 United States
Primary
Concomitant
Sepsis Hospitalization 1/25/2011 55 Male 276 lb 2/17/2011 Consumer United States
Primary
Concomitant
Mass Other Serious 2/10/2011 55 Male 3/7/2011 Other Health Professional United States
Primary
Concomitant
Skin Disorder Other Serious 2/15/2011 68 Male 3/11/2011 United States
Primary
Concomitant
Overdose Other Serious 12/27/2010 46 Female 180 lb 3/29/2011 United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/27/2011 48 Female 182 lb 4/1/2011 United States
Primary
Concomitant
Heart Rate Decreased Other Serious 12/28/2010 45 Female 4/19/2011 Other Health Professional United States
Primary
Concomitant
Mass Other Serious 2/10/2011 55 Male 5/5/2011 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 2/14/2011 61 Male 237 lb 5/20/2011 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 2/11/2011 58 Male 181 lb 5/26/2011 United States
Primary
Concomitant
Retinal Tear Other Serious 2/14/2011 61 Male 237 lb 5/27/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 2/14/2011 61 Male 237 lb 6/8/2011 Consumer United States
Primary
Concomitant
Otitis Media Other Serious 12/17/2010 78 Female 6/10/2011 Other Health Professional United States
Primary
Concomitant
Macular Degeneration Other Serious 2/14/2011 61 Male 237 lb 6/14/2011 United States
Primary
Concomitant
Macular Degeneration Hospitalization 2/14/2011 61 Male 237 lb 6/16/2011 United States
Primary
Concomitant
Dyspnoea Other Serious 6/13/2011 59 Female 6/27/2011 United States
Primary
Concomitant
Influenza Other Serious 1/1/2011 48 Female 6/27/2011 Consumer United States
Primary
Concomitant
Uhthoff's Phenomenon Hospitalization Female 302 lb 7/6/2011 Physician United States
Primary
Concomitant
Macular Degeneration Hospitalization 2/14/2011 61 Male 237 lb 7/11/2011 United States
Primary
Concomitant
Anger Other Serious 12/28/2010 45 Female 7/1/2011 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/8/2010 56 Female 134 lb 7/18/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 11/8/2010 56 Female 134 lb 7/20/2011 Physician United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 5/31/2011 36 Female 302 lb 7/29/2011 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 4/1/2011 64 Female 8/5/2011 Physician United States
Primary
Concomitant
Gait Disturbance Other Serious 6/11/2011 60 Female 320 lb 8/11/2011 Physician United States
Primary
Concomitant
Eye Swelling Other Serious 7/2/2011 70 Female 8/17/2011 Consumer United States
Primary
Concomitant
Malaise Other Serious 5/18/2011 52 Male 301 lb 8/18/2011 United States
Primary
Concomitant
Dyspnoea Disability 6/1/2011 48 Female 8/19/2011 United States
Primary
Concomitant
Cold Sweat Other Serious 2/15/2011 68 Male 9/9/2011 Consumer United States
Primary
Concomitant
Dizziness Other Serious 7/2/2011 45 Female 160 lb 9/28/2011 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 1/11/2011 37 Female 9/29/2011 United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 4/1/2011 64 Female 9/29/2011 Physician United States
Primary
Concomitant
Feeling Abnormal Other Serious 7/2/2011 45 Female 160 lb 10/3/2011 Consumer United States
Primary
Concomitant
Hypertension Other Serious 7/1/2011 45 Female 165 lb 10/12/2011 United States
Primary
Concomitant
Gait Disturbance Hospitalization 9/12/2011 36 Female 122 lb 10/13/2011 Consumer United States
Primary
Concomitant
Coordination Abnormal Other Serious 6/13/2011 59 Female 10/13/2011 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/7/2011 52 Female 187 lb 10/14/2011 United States
Primary
Concomitant
Micturition Urgency Other Serious 8/30/2011 44 Female 10/19/2011 Consumer United States
Primary
Concomitant
Hypertension Other Serious 7/1/2011 45 Female 166 lb 10/20/2011 United States
Primary
Concomitant
Dyspnoea Other Serious 6/1/2011 58 Female 10/21/2011 Consumer United States
Primary
Concomitant
Dysarthria Other Serious 6/1/2011 58 Female 10/27/2011 United States
Primary
Concomitant
Dehydration Other Serious 1/11/2011 37 Female 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Cystoid Macular Oedema Other Serious 9/2/2011 67 Male 408 lb 10/28/2011 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Death 9/28/2011 32 Female 11/15/2011 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 6/26/2011 Male 9/8/2011 Physician United States
Primary
Concomitant
Somnolence 7/19/2011 46 Male 205 lb 9/8/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 12/28/2010 45 Female 9/8/2011 Physician United States
Primary
Concomitant
Photophobia 6/21/2011 67 Male 185 lb 9/8/2011 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 9/30/2011 32 Female 12/9/2011 United States
Primary
Concomitant
Pain In Extremity 7/14/2011 65 Female 9/8/2011 Consumer United States
Primary
Concomitant
Hypoaesthesia 7/15/2011 50 Female 200 lb 9/8/2011 Consumer United States
Primary
Concomitant
Peripheral Sensorimotor Neuropathy Other Serious 5/1/2011 43 Female 9/8/2011 Consumer United States
Primary
Concomitant
Headache 4/7/2011 41 Female 165 lb 9/8/2011 Other Health Professional United States
Primary
Concomitant
Asthenia 5/1/2011 50 Female 9/8/2011 Physician United States
Primary
Concomitant
Muscular Weakness 56 Male 160 lb 9/8/2011 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Pain 5/21/2011 46 Female 248 lb 9/8/2011 Physician United States
Primary
Concomitant
Myalgia 5/27/2011 52 Female 9/8/2011 Physician Afghanistan
Primary
Concomitant
Tongue Disorder 38 Female 171 lb 9/8/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral 1/1/2011 46 Female 138 lb 9/8/2011 Physician United States
Primary
Concomitant
Contusion Other Serious 1/11/2011 37 Female 92 lb 12/22/2011 United States
Primary
Secondary
Concomitant
Death Death 12/11/2011 44 Female 12/29/2011 United States
Primary
Secondary
Concomitant
Asthenia Death 12/11/2011 44 Female 1/6/2012 Consumer United States
Primary
Secondary
Concomitant
Death Death 12/11/2011 44 Female 1/10/2012 Consumer Japan
Primary
Secondary
Concomitant
Death Death 12/11/2011 44 Female 1/10/2012 Consumer Japan
Primary
Secondary
Concomitant
Malaise Disability 11/1/2011 37 Female 235 lb 1/12/2012 Other Health Professional United States
Primary
Concomitant
Death Death 12/11/2011 44 Female 1/12/2012 Consumer Japan
Primary
Secondary
Concomitant
Asthenia Death 12/11/2011 44 Female 1/9/2012 Consumer United States
Primary
Secondary
Stress Other Serious 9/2/2011 47 Female 110 lb 1/19/2012 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2011 32 Female 1/20/2012 Consumer United States
Primary
Concomitant
Cachexia Death 12/11/2011 44 Female 99 lb 1/20/2012 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Death Female 99 lb 1/26/2012 Physician United States
Primary
Secondary
Concomitant
Cachexia Death 12/11/2011 44 Female 1/30/2012 Consumer Japan
Primary
Secondary
Concomitant
Pneumonia Death 12/11/2011 44 Female 1/30/2012 Physician Japan
Primary
Secondary
Concomitant
Asthenia Death 12/11/2011 44 Female 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite 11/15/2011 51 Female 178 lb 12/5/2011 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 6/26/2011 Male 12/5/2011 Physician United States
Primary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 10/26/2011 36 Female 185 lb 12/5/2011 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 46 Female 165 lb 12/5/2011 Other Health Professional United States
Primary
Concomitant
Constipation Other Serious 12/28/2010 46 Female 12/5/2011 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2011 36 Female 12/5/2011 Other Health Professional United States
Primary
Concomitant
Headache Other Serious 2/8/2011 55 Female 12/5/2011 Physician United States
Primary
Concomitant
Malaise Other Serious 1/1/2011 48 Female 2/6/2012 Consumer United States
Primary
Concomitant
Cachexia Death 12/11/2011 44 Female 99 lb 2/7/2012 Physician United States
Primary
Secondary
Concomitant
Apathy 49 Female 12/5/2011 Physician United States
Primary
Concomitant
Back Pain 9/12/2011 46 Female 110 lb 12/5/2011 Consumer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 5/5/2011 53 Female 12/5/2011 Consumer United States
Primary
Concomitant
Mobility Decreased 56 Male 160 lb 12/5/2011 Other Health Professional United States
Primary
Concomitant
Balance Disorder 5/21/2011 46 Female 12/5/2011 Physician United States
Primary
Concomitant
Back Pain 4/19/2011 47 Female 12/5/2011 Physician United States
Primary
Concomitant
Fatigue 10/3/2011 33 Female 114 lb 12/5/2011 Consumer United States
Primary
Concomitant
Hypoaesthesia Other Serious 7/1/2011 50 Female 2/9/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral 10/11/2011 58 Female 12/5/2011 Physician United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 5/1/2011 50 Female 118 lb 12/5/2011 Physician United States
Primary
Concomitant
Headache 6/21/2011 67 Male 185 lb 12/5/2011 Other Health Professional United States
Primary
Concomitant
Blood Pressure Decreased Death 12/11/2011 44 Female 2/10/2012 Consumer Japan
Primary
Secondary
Concomitant
Fall Death 12/11/2011 44 Female 2/10/2012 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Death 12/11/2011 44 Female 2/20/2012 Consumer Japan
Primary
Secondary
Concomitant
Multiple Sclerosis Death 9/28/2011 32 Female 2/20/2012 Physician United States
Primary
Concomitant
Drug Ineffective Death 12/11/2011 44 Female 2/20/2012 Physician Japan
Primary
Secondary
Concomitant
Hypoaesthesia Death 9/28/2011 32 Female 2/27/2012 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 2/14/2011 61 Male 237 lb 2/29/2012 Consumer United States
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 2/14/2012 52 Female 92 lb 3/5/2012 United States
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 2/14/2012 52 Female 92 lb 3/6/2012 United States
Primary
Concomitant
Malaise Disability 11/1/2011 37 Female 236 lb 3/6/2012 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2012 50 Male 3/13/2012 Other Health Professional United States
Primary
Concomitant
Non-cardiac Chest Pain 12/17/2011 45 Female 182 lb 3/13/2012 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Death 9/29/2011 32 Female 3/19/2012 Other Health Professional United States
Primary
Concomitant
Peroneal Nerve Palsy Other Serious 6/1/2011 58 Female 3/23/2012 Physician United States
Primary
Concomitant
Injection Site Erythema Other Serious 47 Female 2/16/2012 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Life Threatening 12/6/2011 57 Female 255 lb 3/29/2012 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/19/2012 59 Female 133 lb 4/9/2012 Physician United States
Primary
Concomitant
Headache Other Serious 9/14/2011 53 Female 4/11/2012 Consumer United States
Primary
Concomitant
Back Pain Other Serious 9/2/2011 47 Female 110 lb 4/24/2012 Pharmacist United States
Primary
Concomitant
Feeling Hot 1/13/2011 48 Female 6/24/2011 Other Health Professional United States
Primary
Concomitant
Sinus Arrhythmia 10/25/2010 56 Female 12/27/2010 Other Health Professional United States
Primary
Concomitant
Abdominal Discomfort 5/26/2011 57 Female 154 lb 6/24/2011 Other Health Professional United States
Primary
Concomitant
Headache 2/16/2011 41 Female 6/24/2011 Other Health Professional United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 5/12/2011 54 Female 158 lb 6/24/2011 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 4/28/2011 35 Female 100 lb 6/24/2011 Physician United States
Primary
Concomitant
Heart Rate Decreased Other Serious 12/28/2010 45 Female 3/24/2011 Physician United States
Primary
Concomitant
Heart Rate Decreased Other Serious 2/3/2011 49 Female 256 lb 3/24/2011 Physician United States
Primary
Concomitant
Dizziness 1/29/2011 42 Female 145 lb 3/24/2011 Physician United States
Primary
Concomitant
Hypoaesthesia 10/25/2010 56 Female 12/27/2010 Other Health Professional United States
Primary
Concomitant
Muscle Spasms 4/9/2011 40 Female 6/24/2011 Consumer United States
Primary
Concomitant
Flushing 2/16/2011 41 Female 6/24/2011 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Other Serious 11/8/2010 56 Female 134 lb 5/1/2012 Physician United States
Primary
Concomitant
Muscle Spasms 4/9/2011 40 Female 6/24/2011 Consumer United States
Primary
Concomitant
Central Nervous System Lesion Other Serious Female 5/3/2012 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 6/1/2011 54 Female 5/7/2012 Physician United States
Primary
Concomitant
Alopecia 39 Female 6/24/2011 Consumer United States
Primary
Concomitant
Fatigue 10/17/2010 21 Male 180 lb 3/24/2011 Consumer United States
Primary
Concomitant
Enzyme Abnormality 4/23/2011 48 Female 6/24/2011 Physician United States
Primary
Concomitant
Poor Peripheral Circulation 4/19/2011 47 Female 140 lb 6/24/2011 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 1/11/2011 37 Female 92 lb 5/10/2012 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 6/1/2011 54 Female 5/11/2012 Consumer United States
Primary
Concomitant
Cough Other Serious 5/1/2011 47 Female 5/14/2012 Consumer United States
Primary
Concomitant
Headache Other Serious 2/3/2011 49 Female 256 lb 3/24/2011 Physician United States
Primary
Concomitant
Malaise Other Serious 3/30/2012 47 Female 5/25/2012 Other Health Professional United States
Primary
Concomitant
Neck Pain Other Serious 9/2/2011 47 Female 99 lb 6/5/2012 Consumer United States
Primary
Concomitant
Dizziness Other Serious 5/21/2011 47 Female 6/8/2012 Consumer Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2012 50 Male 6/11/2012 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 10/1/2011 Female 6/26/2012 Consumer United Kingdom
Primary
Concomitant
Central Nervous System Lesion Other Serious Female 6/28/2012 Consumer United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization 4/12/2012 66 Female 6/29/2012 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 6/27/2011 36 Female 302 lb 7/2/2012 Physician United States
Primary
Concomitant

Drug Data