Gilenya combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Kidney Infection Other Serious 12/23/2010 47 Female 1/4/2011 Consumer United States
Primary
Concomitant
Fatigue Other Serious 1/26/2011 40 Female 2/8/2011 Consumer United States
Primary
Concomitant
Cough Other Serious 12/23/2010 47 Female 2/9/2011 United States
Primary
Concomitant
Vomiting Other Serious 1/8/2011 48 Female 118 lb 2/14/2011 Consumer United States
Primary
Concomitant
Skin Wrinkling Other Serious 2/16/2011 54 Female 254 lb 3/10/2011 United States
Primary
Concomitant
Back Pain Other Serious 2/27/2011 46 Female 4/1/2011 Consumer United States
Primary
Concomitant
Faecal Incontinence Other Serious 4/3/2011 42 Female 240 lb 4/25/2011 Consumer United States
Primary
Concomitant
Renal Cancer Other Serious 3/1/2011 36 Female 5/3/2011 Physician United States
Primary
Concomitant
Dehydration Hospitalization 1/11/2011 37 Female 5/3/2011 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2011 41 Female 6/14/2011 United States
Primary
Concomitant
Renal Cancer Other Serious 4/1/2011 36 Female 6/30/2011 Physician United States
Primary
Concomitant
Eye Pain Other Serious 7/6/2011 44 Female 123 lb 7/14/2011 United States
Primary
Concomitant
Eosinophil Count Decreased Hospitalization 7/5/2011 41 Female 7/20/2011 Physician United States
Primary
Concomitant
Conjunctivitis Other Serious 2/18/2011 44 Female 8/1/2011 United States
Primary
Concomitant
Dyspnoea Other Serious 44 Female 8/4/2011 Consumer United States
Primary
Concomitant
Feeling Hot Other Serious 7/6/2011 50 Female 200 lb 8/9/2011 Physician United States
Primary
Concomitant
Hypotension Hospitalization 7/5/2011 41 Female 8/18/2011 Consumer United States
Primary
Concomitant
Heart Rate Irregular Other Serious 1/26/2011 40 Female 8/25/2011 Consumer United States
Primary
Concomitant
Limb Discomfort Hospitalization 5/23/2011 61 Female 8/25/2011 United States
Primary
Concomitant
Fatigue 6/27/2011 41 Female 9/6/2011 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 4/29/2010 34 Female 161 lb 9/6/2011 Consumer United States
Primary
Concomitant
Chest Discomfort Hospitalization 7/6/2011 50 Female 200 lb 9/6/2011 United States
Primary
Concomitant
Limb Discomfort Hospitalization 5/23/2011 61 Female 9/29/2011 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 1/11/2011 37 Female 9/29/2011 United States
Primary
Secondary
Concomitant
Migraine Other Serious 8/1/2011 57 Female 120 lb 9/29/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 4/19/2011 43 Female 139 lb 10/10/2011 United States
Primary
Concomitant
Gait Spastic Other Serious 9/5/2011 71 Female 180 lb 10/10/2011 United States
Primary
Concomitant
Chest Pain Other Serious 8/6/2011 58 Female 121 lb 10/18/2011 United States
Primary
Concomitant
Micturition Urgency Other Serious 8/30/2011 44 Female 10/19/2011 Consumer United States
Primary
Concomitant
Visual Impairment 9/27/2011 36 Female 10/20/2011 Consumer United States
Primary
Concomitant
Cerumen Impaction 6/27/2011 41 Female 10/27/2011 Consumer United States
Primary
Concomitant
Dehydration Other Serious 1/11/2011 37 Female 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/29/2011 43 Female 11/4/2011 Consumer United States
Primary
Concomitant
Drug Dependence Hospitalization 9/22/2011 44 Female 11/11/2011 Physician United States
Primary
Concomitant
Contusion 1/26/2011 40 Female 11/16/2011 United States
Primary
Concomitant
Migraine Other Serious 8/6/2011 58 Female 121 lb 11/18/2011 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/13/2011 47 Female 171 lb 9/8/2011 Physician United States
Primary
Concomitant
Malaise Other Serious 3/15/2011 41 Female 9/8/2011 Physician United States
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 4/17/2011 47 Female 9/8/2011 Consumer United States
Primary
Concomitant
Headache Other Serious 5/11/2011 44 Male 180 lb 9/8/2011 Physician United States
Primary
Concomitant
Renal Disorder 6/17/2011 54 Female 9/8/2011 Physician United States
Primary
Concomitant
Fatigue 6/27/2011 42 Female 9/8/2011 Physician United States
Primary
Concomitant
Cystitis Other Serious 44 Female 9/8/2011 Physician United States
Primary
Concomitant
Dizziness Postural 8/20/2011 24 Female 9/8/2011 Consumer United States
Primary
Concomitant
Bradycardia 8/11/2011 52 Female 362 lb 9/8/2011 Physician United States
Primary
Concomitant
Dizziness Other Serious 6/15/2011 55 Female 9/8/2011 Physician United States
Primary
Concomitant
Paraesthesia 4/5/2011 49 Female 9/8/2011 Other Health Professional United States
Primary
Concomitant
Headache 3/4/2011 32 Female 9/8/2011 Physician United States
Primary
Concomitant
Claustrophobia Other Serious 6/25/2011 51 Female 9/8/2011 Physician United States
Primary
Concomitant
Pain Other Serious 2/16/2011 54 Female 254 lb 12/14/2011 Consumer United States
Primary
Concomitant
Contusion Other Serious 1/11/2011 37 Female 92 lb 12/22/2011 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 11/21/2011 41 Female 12/27/2011 United States
Primary
Concomitant
Sinusitis Hospitalization 10/29/2011 43 Female 12/28/2011 United States
Primary
Concomitant
Dyspnoea Other Serious 7/6/2011 50 Female 200 lb 1/2/2012 Physician United States
Primary
Concomitant
Bronchitis Other Serious 10/29/2011 43 Female 1/2/2012 Other Health Professional United States
Primary
Concomitant
Bronchitis Hospitalization 11/7/2011 57 Female 1/23/2012 United States
Primary
Concomitant
Dyspnoea Hospitalization 11/1/2011 57 Female 1/30/2012 Consumer United States
Primary
Concomitant
Migraine Other Serious 4/19/2011 43 Female 139 lb 1/31/2012 Other Health Professional United States
Primary
Concomitant
Fatigue 11/22/2011 43 Female 12/5/2011 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 6/24/2011 51 Female 12/5/2011 Physician United States
Primary
Concomitant
Migraine Other Serious 8/26/2011 29 Female 12/5/2011 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 8/24/2011 38 Female 197 lb 12/5/2011 Physician United States
Primary
Concomitant
Headache Other Serious 2/8/2011 55 Female 12/5/2011 Physician United States
Primary
Concomitant
Photopsia Other Serious 6/13/2011 47 Female 171 lb 12/5/2011 Physician United States
Primary
Concomitant
Alopecia 10/3/2011 53 Female 145 lb 12/5/2011 Physician United States
Primary
Concomitant
Sleep Disorder 8/31/2011 32 Female 12/5/2011 Physician United States
Primary
Concomitant
Malaise 9/30/2011 36 Female 117 lb 12/5/2011 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness 11/6/2011 33 12/5/2011 Consumer United States
Primary
Concomitant
Headache 2/16/2011 41 Female 12/5/2011 Other Health Professional United States
Primary
Concomitant
Overdose 7/13/2011 52 Female 344 lb 12/5/2011 Physician United States
Primary
Concomitant
Pain In Extremity 8/16/2011 52 Female 12/5/2011 Other Health Professional United States
Primary
Concomitant
Fall 6/27/2011 42 Female 12/5/2011 Physician United States
Primary
Concomitant
Renal Disorder 6/17/2011 54 Female 12/5/2011 Physician United States
Primary
Concomitant
Feeling Abnormal Hospitalization 2/1/2011 47 Female 2/17/2012 Other Health Professional United States
Primary
Concomitant
Back Pain Hospitalization Female 3/15/2012 Consumer United States
Primary
Concomitant
Central Nervous System Lesion Hospitalization Female 3/19/2012 Consumer United States
Primary
Concomitant
Optic Neuritis 3/2/2012 52 Female 3/20/2012 Physician United States
Primary
Concomitant
Convulsion Other Serious 3/12/2012 27 Female 3/27/2012 Physician United States
Primary
Concomitant
Injection Site Erythema Other Serious 47 Female 2/16/2012 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Pain Hospitalization Female 3/29/2012 Consumer United States
Primary
Concomitant
Cough Other Serious 3/12/2012 27 Female 4/11/2012 Consumer United States
Primary
Concomitant
Rash Life Threatening 6/14/2011 35 Female 263 lb 4/20/2012 Consumer United States
Primary
Concomitant
Dysgeusia 2/9/2011 52 Female 241 lb 6/24/2011 Physician United States
Primary
Concomitant
Nightmare 1/20/2011 50 Female 6/24/2011 Physician United States
Primary
Concomitant
Headache 2/16/2011 41 Female 6/24/2011 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 3/22/2011 58 Female 134 lb 6/24/2011 Physician United States
Primary
Concomitant
Eye Pain Other Serious 1/1/2011 33 Female 6/24/2011 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 4/28/2011 35 Female 100 lb 6/24/2011 Physician United States
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 4/17/2011 47 Female 6/24/2011 Consumer United States
Primary
Concomitant
Heart Rate Decreased Other Serious 2/3/2011 49 Female 256 lb 3/24/2011 Physician United States
Primary
Concomitant
Oedema Peripheral 11/11/2010 32 Female 220 lb 3/24/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Postural 1/12/2011 62 Female 3/24/2011 Physician United States
Primary
Concomitant
Fibromyalgia 3/4/2011 32 Female 6/24/2011 Physician United States
Primary
Concomitant
Palpitations Other Serious 1/27/2012 39 Female 4/30/2012 Physician United States
Primary
Concomitant
Pain 4/6/2011 49 Female 6/24/2011 Other Health Professional United States
Primary
Concomitant
Fatigue 1/20/2011 50 Female 6/24/2011 Physician United States
Primary
Concomitant
Flushing 2/16/2011 41 Female 6/24/2011 Other Health Professional United States
Primary
Concomitant
Chills 2/23/2011 33 Female 3/24/2011 Consumer United States
Primary
Concomitant
Hypoaesthesia 10/25/2010 56 Female 3/24/2011 Other Health Professional United States
Primary
Concomitant
Visual Impairment Hospitalization 1/11/2011 37 Female 92 lb 5/10/2012 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral 11/11/2010 32 Female 220 lb 3/24/2011 Other Health Professional United States
Primary
Concomitant
Secondary Progressive Multiple Sclerosis Other Serious 3/15/2011 41 Female 6/24/2011 Consumer United States
Primary
Concomitant
Cough Other Serious 5/1/2011 47 Female 5/14/2012 Consumer United States
Primary
Concomitant
Headache Other Serious 2/3/2011 49 Female 256 lb 3/24/2011 Physician United States
Primary
Concomitant
Tremor Other Serious 3/22/2011 58 Female 134 lb 6/24/2011 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious Female 5/18/2012 Consumer United States
Primary
Concomitant
Depression Hospitalization 5/23/2011 61 Female 5/28/2012 Other Health Professional United States
Primary
Concomitant
Depression Other Serious 4/14/2012 34 Female 5/30/2012 Consumer United States
Primary
Concomitant
Amnesia Hospitalization Female 6/19/2012 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 1/1/2012 37 Female 6/21/2012 Pharmacist Canada
Primary
Concomitant
Malaise Other Serious 11/6/2011 33 Female 163 lb 6/27/2012 Physician United States
Primary
Concomitant
Bundle Branch Block Other Serious 5/21/2012 37 Female 160 lb 7/2/2012 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 4/3/2012 44 Female 7/5/2012 Other Health Professional United States
Primary
Concomitant
Clumsiness Other Serious 6/15/2012 51 Female 193 lb 7/6/2012 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 9/28/2011 50 Female 127 lb 7/12/2012 Consumer United States
Primary
Secondary
Concomitant
Convulsion Other Serious 9/28/2011 50 Female 127 lb 7/12/2012 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 12/1/2011 42 Female 170 lb 7/17/2012 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 9/24/2011 51 Female 193 lb 7/25/2012 Other Health Professional United States
Primary
Concomitant
Asthenia Hospitalization 5/23/2011 61 Female 8/2/2012 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 9/24/2011 51 Female 193 lb 8/2/2012 Consumer United States
Primary
Concomitant
Eye Pain Disability 8/25/2011 66 Female 195 lb 8/7/2012 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 4/1/2011 43 Female 8/9/2012 Physician United States
Primary
Concomitant
Rash Other Serious 6/25/2012 24 Female 8/9/2012 Physician United States
Primary
Concomitant
Tinnitus 6/27/2011 42 Female 3/6/2012 Physician Us
Primary
Concomitant
Weight Decreased Other Serious 8/26/2011 29 Female 9/7/2012 Physician Us
Primary
Concomitant
Progressive Multiple Sclerosis Other Serious 8/30/2011 45 Female 5/17/2013 Consumer Country Not Specified
Primary
Concomitant
Tachypnoea Life Threatening 9/22/2011 45 Female 5/3/2013 Consumer Us
Primary
Concomitant
Vision Blurred Other Serious 6/13/2011 47 Female 171 lb 6/6/2012 Other Health Professional Us
Primary
Concomitant
Vitamin D Increased 8/16/2011 52 Female 6/6/2012 Other Health Professional Us
Primary
Concomitant
Vertigo 9/28/2011 51 Female 127 lb 11/2/2012 Consumer Us
Primary
Secondary
Concomitant
Bundle Branch Block Other Serious 6/27/2012 38 Female 160 lb 9/20/2012 Consumer Us
Primary
Concomitant
Visual Impairment Life Threatening 9/24/2011 51 Female 172 lb 11/24/2012 Consumer Us
Primary
Concomitant
Visual Impairment Other Serious 7/20/2012 Female 190 lb 9/11/2012 Other Health Professional Us
Primary
Concomitant
Neuralgia Other Serious 7/19/2012 54 Female 9/11/2012 Consumer Country Not Specified
Primary
Concomitant
Visual Impairment Other Serious 7/11/2012 46 Female 217 lb 9/3/2012 Consumer Country Not Specified
Primary
Concomitant
Red Cell Distribution Width Increased Other Serious 6/20/2012 42 Female 190 lb 10/26/2012 Consumer Us
Primary
Concomitant
Urinary Tract Infection Other Serious 12/2011 Female 9/17/2012 Consumer Us
Primary
Concomitant
Urinary Tract Infection 12/5/2011 52 Female 6/6/2012 Consumer Us
Primary
Concomitant
Loss Of Consciousness Other Serious 3/23/2012 Female 1/25/2013 Physician It
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 8/10/2012 43 Female 10/19/2012 Consumer Ie
Primary
Concomitant
Visual Impairment Other Serious 7/23/2012 40 Female 10/9/2012 Consumer Country Not Specified
Primary
Concomitant
Vision Blurred Other Serious 3/16/2012 36 Female 262 lb 12/3/2012 Other Health Professional Us
Primary
Concomitant
Pyrexia Other Serious 6/2012 Female 10/19/2012 Consumer Country Not Specified
Primary
Concomitant
Vision Blurred Other Serious 4/2012 Female 123 lb 11/4/2012 Consumer Us
Primary
Concomitant
Stress Hospitalization 10/5/2012 37 Female 11/24/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Vitreous Floaters Other Serious 2/22/2012 44 Female 397 lb 12/31/2012 Consumer Us
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 6/20/2012 31 Female 12/12/2012 Other Health Professional It
Primary
Concomitant
Heart Rate Abnormal Hospitalization 2/13/2013 52 Female 141 lb 5/15/2013 Other Health Professional Us
Primary
Concomitant
Nausea Other Serious 12/2012 38 Female 2/20/2013 Consumer Mx
Primary
Concomitant
Weight Decreased Hospitalization 1/11/2011 38 Female 92 lb 5/21/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data