Furosemide combined with Voriconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 2/18/2006 Other Health Professional United States
Primary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 4/1/2006 United States
Primary
Concomitant
Thrombocytopenia Death 3/26/2006 73 Male 4/24/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/28/2005 84 Female 8/25/2006 Physician Japan
Primary
Concomitant
Systemic Candida Hospitalization 8/2/2006 67 Male 9/1/2006 France
Primary
Concomitant
Systemic Candida Hospitalization 8/2/2006 67 Male 9/12/2006 France
Primary
Concomitant
Systemic Candida Hospitalization 8/2/2006 67 Male 9/13/2006 Physician France
Primary
Concomitant
Weight Increased Hospitalization 4/25/2006 58 Male 132 lb 10/4/2006 Physician Japan
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 3/26/2003 68 Male 174 lb 10/18/2006 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Death 9/10/2006 60 Female 176 lb 11/3/2006 Physician Australia
Primary
Concomitant
Weight Increased Hospitalization 4/25/2006 58 Male 132 lb 12/8/2006 Physician Japan
Primary
Concomitant
Mucormycosis Required Intervention 11/9/2006 73 Male 168 lb 12/21/2006 Physician Spain
Primary
Concomitant
Weight Increased Hospitalization 4/26/2006 58 Male 132 lb 12/21/2006 Physician Japan
Primary
Concomitant
Pseudoporphyria Other Serious 4/1/2005 55 Female 2/27/2007 United Kingdom
Primary
Concomitant
Ventricular Dysfunction Other Serious 3/28/2006 7 Male 4/12/2007 United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 8/13/2007 10 Female 75 lb 9/11/2007 Pharmacist United States
Primary
Concomitant
Respiratory Failure Required Intervention 7/10/2007 69 Male 7/13/2007 United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 98 lb 6/20/2007 United States
Primary
Concomitant
Sepsis Hospitalization 7/23/2007 Male 139 lb 11/7/2007 United States
Primary
Secondary
Concomitant
Drug Level Increased Death 7/26/2007 56 Male 168 lb 11/26/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Level Increased Death 7/26/2007 56 Male 168 lb 12/3/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/23/2007 Male 139 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 10/5/2007 36 Male 1/16/2008 Netherlands
Primary
Concomitant
Hypokalaemia Life Threatening 2/4/2008 Female 2/20/2008 Physician United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/13/2008 11 Female 44 lb 2/26/2008 Physician Ireland
Primary
Concomitant
Hypokalaemia Life Threatening 2/4/2008 Female 3/17/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/13/2008 11 Female 44 lb 3/13/2008 Ireland
Primary
Concomitant
Renal Failure Life Threatening 2/4/2008 Female 4/17/2008 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Death 3/8/2008 14 Female 4/25/2008 Physician Italy
Primary
Secondary
Concomitant
Cardiac Failure Death 3/8/2008 14 Female 5/6/2008 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 5/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/4/2008 Female 5/27/2008 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 6/1/2008 Female 106 lb 7/16/2008 Physician Denmark
Primary
Concomitant
Metabolic Acidosis Life Threatening 7/31/2008 Female 8/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Life Threatening 7/31/2008 Female 8/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious 6/1/2008 Female 106 lb 9/8/2008 Physician Denmark
Primary
Concomitant
Drug Level Increased Other Serious 7/26/2007 56 Male 168 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 8/1/2000 54 Female 170 lb 9/5/2008 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Life Threatening 7/31/2008 Female 9/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 10/14/2008 Male 10/27/2008 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 10/14/2008 Male 95 lb 11/18/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 10/14/2008 Male 95 lb 12/2/2008 Physician Japan
Primary
Secondary
Concomitant
Arrhythmia Death 11/29/2008 12/11/2008 Physician Italy
Primary
Secondary
Concomitant
Arrhythmia Death 11/29/2008 12/16/2008 Physician Italy
Primary
Secondary
Concomitant
Sepsis Other Serious 65 Male 12/18/2008
Primary
Secondary
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 10/5/2007 36 Male 2/13/2009 Netherlands
Primary
Concomitant
Arrhythmia Death 11/29/2008 2/24/2009 Physician Italy
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Hospitalization 1/26/2009 Male 177 lb 2/26/2009 Sweden
Primary
Secondary
Concomitant
Septic Shock Death 3/4/2009 4/3/2009 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/23/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/29/2009 Other Health Professional United States
Primary
Concomitant
Blood Bilirubin Increased Required Intervention 2/22/2009 30 Female 235 lb 2/24/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 5/7/2009 Female 187 lb 5/20/2009 Physician Germany
Primary
Concomitant
Respiratory Distress Death 1/18/2009 48 5/21/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 5/25/2009 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Hospitalization 4/9/2009 Male 56 lb 5/27/2009 United States
Primary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Septic Shock Death 3/4/2009 64 6/30/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Cardiac Failure Death 11/11/2007 58 7/7/2009 Physician Korea, Republic Of
Primary
Concomitant
Septic Shock Death 12/27/2007 16 8/12/2009 Physician Korea, Republic Of
Primary
Concomitant
Somnolence Hospitalization 8/11/2009 Male 39 lb 8/18/2009 United States
Primary
Secondary
Concomitant
Cardiac Failure Death 11/11/2007 58 8/28/2009 Physician Korea, Republic Of
Primary
Concomitant
Septic Shock Death 12/27/2007 16 8/28/2009 Physician Korea, Republic Of
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2009 Male 8/31/2009 Netherlands
Primary
Concomitant
Somnolence Hospitalization 8/11/2009 Male 39 lb 8/24/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/30/2009 59 Male 9/16/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 9/12/2009 Physician Japan
Primary
Concomitant
Septic Shock Death 12/27/2007 16 9/21/2009 Physician Korea, Republic Of
Primary
Concomitant
Venoocclusive Disease Hospitalization 8/11/2009 Male 39 lb 9/16/2009 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 7/24/2009 60 Male 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 3/30/2009 59 Male 10/7/2009 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 10/15/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 10/9/2009 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 7/24/2009 60 Male 223 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 7/24/2009 60 Male 223 lb 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 3/20/2009 57 Female 11/20/2009 Consumer France
Primary
Secondary
Concomitant
Thyroid Disorder Required Intervention 57 Male 12/8/2009 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/26/2009 Male 177 lb 12/23/2009 Sweden
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 9/25/2009 63 Female 10/10/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 57 Male 12/22/2009 United States
Primary
Secondary
Concomitant
Stenotrophomonas Infection Other Serious 10/5/2006 35 Female 1/25/2010
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 1/29/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pseudoporphyria Other Serious 4/1/2005 55 Female 143 lb 2/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Arrhythmia Death 11/29/2008 66 Male 198 lb 3/30/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 4/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deafness Required Intervention 1/5/2010 67 Female 108 lb 4/25/2010 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2 Male 24 lb 5/20/2010 Physician Japan
Primary
Concomitant
Stem Cell Transplant Hospitalization 4/12/2010 2 Male 24 lb 6/18/2010 Physician Japan
Primary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bradycardia Death 7/22/2010 68 Female 143 lb 7/29/2010 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bradycardia Death 7/22/2010 68 Female 143 lb 8/3/2010 Physician France
Primary
Secondary
Concomitant
Hypotension Death 7/22/2010 68 Female 143 lb 8/13/2010 Consumer United States
Primary
Secondary
Concomitant
Hypotension Death 7/22/2010 68 Female 143 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 5/21/2010 59 Male 163 lb 9/28/2010 Physician Netherlands
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 8/17/2010 77 Male 9/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 2/8/2010 15 Female 110 lb 10/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 5/21/2010 59 Male 163 lb 10/20/2010 Physician Netherlands
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 3/15/2009 38 Male 128 lb 9/30/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 8/19/2010 77 Male 11/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Death 11/8/2010 2 Male 22 lb 11/8/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 63 Male 11/16/2010
Primary
Secondary
Hypotension Life Threatening 8/5/2010 1 Female 27 lb 11/12/2010 Pharmacist United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 8/3/2009 62 Female 110 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Urosepsis Other Serious 8/29/2010 78 Female 12/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Other Serious 10/12/2010 57 Male 231 lb 12/7/2010 Physician Netherlands
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/28/2010 30 Female 99 lb 1/6/2011 Physician Japan
Primary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 12/30/2009 27 Female 220 lb 1/13/2011 Physician Japan
Primary
Concomitant
Bacterial Test Positive Other Serious 11/20/2010 57 Female 3/11/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Granuloma Other Serious 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Bronchopulmonary Aspergillosis Death 81 Male 3/22/2011 Physician United Kingdom
Primary
Concomitant
Respiratory Arrest Death 11/30/2009 27 Female 220 lb 3/22/2011 Physician Japan
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/8/2009 46 Female 220 lb 4/8/2011 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/4/2011 81 Male 3/31/2011 Physician United Kingdom
Primary
Concomitant
Sopor Hospitalization 12/6/2010 Male 4/26/2011 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Fungal Infection Other Serious 10/13/2009 36 Male 143 lb 4/27/2011 Physician Japan
Primary
Concomitant
Atrial Fibrillation Other Serious 12/1/2010 71 Female 127 lb 4/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 4/15/2011 24 Female 5/3/2011 Physician Spain
Primary
Concomitant
Bradycardia Death 7/22/2010 68 Female 143 lb 6/15/2011 Physician France
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/22/2011 53 Female 6/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Viral Haemorrhagic Cystitis Death 7/28/2010 30 Female 99 lb 6/22/2011 Physician Japan
Primary
Concomitant
Hyperkalaemia Death 7/22/2010 68 Female 143 lb 6/23/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Potassium Increased Death 7/22/2010 68 Female 143 lb 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 7/21/2010 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Life Threatening 4/22/2010 13 Male 90 lb 7/5/2011 Physician Japan
Primary
Concomitant
Nephritic Syndrome Other Serious 11/5/2009 45 Male 175 lb 7/15/2011 Physician Brazil
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/17/2010 57 Female 7/21/2011 Other Health Professional United States
Primary
Concomitant
Bradycardia Death 7/22/2010 68 Female 143 lb 7/29/2011 Physician France
Primary
Secondary
Concomitant
Hyperkalaemia Death 7/22/2010 68 Female 143 lb 8/4/2011 Consumer France
Primary
Secondary
Concomitant
Bradycardia Death 7/22/2010 68 Female 143 lb 8/8/2011 Consumer United States
Primary
Concomitant
Lung Infection Hospitalization 5/1/2011 50 Female 122 lb 8/31/2011 Consumer United States
Primary
Concomitant
Nephritic Syndrome Other Serious 11/5/2009 45 Male 175 lb 9/2/2011 Physician Brazil
Primary
Secondary
Concomitant
Nephritic Syndrome Other Serious 11/5/2009 45 Male 175 lb 9/7/2011 Physician Brazil
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/1/2011 50 Female 122 lb 9/9/2011 Consumer United States
Primary
Concomitant

Drug Data