Furosemide combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Heart Rate Increased Life Threatening 8/20/2005 86 Female 2/8/2006 Japan
Primary
Concomitant
Chest Pain Other Serious 3/9/1995 48 Female 142 lb 12/21/2005 Consumer United States
Primary
Concomitant
Renal Failure Death 2/24/2006 55 Female 3/14/2006 United States
Primary
Concomitant
Chest Pain Other Serious 2/20/2005 52 Female 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 1/31/2006 59 Male 4/3/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/1/2005 61 Male 173 lb 5/12/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/9/2005 46 Male 1/13/2006 United States
Primary
Concomitant
Nausea Hospitalization 3/9/2006 79 Female 7/28/2006 Australia
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 4/16/2006 60 Male 300 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/22/2006 46 Female 5/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/22/2006 99 Female 4/20/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 57 Female 1/9/2006 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Death 9/10/2006 60 Female 176 lb 11/3/2006 Physician Australia
Primary
Concomitant
Pneumonia Hospitalization 1/10/2006 6 Female 29 lb 2/8/2007 Physician Japan
Primary
Concomitant
Wrong Drug Administered 12/30/2005 66 Female 300 lb 2/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 35 Female 4/27/2007 Netherlands
Primary
Concomitant
Renal Failure Acute Hospitalization 5/28/2006 Male 5/7/2007 Physician Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/26/2006 85 Female 5/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinusitis Other Serious 11/11/2004 Male 199 lb 6/29/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/23/2006 8 Female 26 lb 6/29/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 5/17/2007 Female 150 lb 9/6/2007 Physician Germany
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 76 Female 10/19/2007 United Kingdom
Primary
Concomitant
Quadriparesis Hospitalization 12/26/2005 81 Female 11/19/2007 France
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/4/2007 72 Female 191 lb 12/24/2007 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/5/2007 Female 1/8/2008 Physician Switzerland
Primary
Concomitant
Epistaxis Hospitalization 11/1/2006 62 Female 11/29/2007 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 10/14/2004 33 Female 2/21/2008 Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/1/2004 33 Female 2/28/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/1/2006 Male 3/7/2008 Physician Australia
Primary
Secondary
Concomitant
Sinusitis Hospitalization 6/6/2006 Male 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 10/14/2004 Female 3/25/2008 France
Primary
Secondary
Concomitant
Sinusitis Hospitalization 5/22/2006 Male 3/26/2008 Consumer France
Primary
Secondary
Concomitant
Perforated Ulcer Other Serious 3/4/2008 Female 3/26/2008 France
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/23/2006 8 26 lb 3/26/2008 Physician Japan
Primary
Concomitant
Musculoskeletal Pain Other Serious 3/4/2008 Female 4/4/2008 France
Primary
Concomitant
Capillary Leak Syndrome Death 11/6/2007 12 Male 4/14/2008 Physician Italy
Primary
Secondary
Concomitant
Sinusitis Hospitalization 5/22/2006 Male 4/15/2008 Consumer France
Primary
Secondary
Concomitant
Capillary Leak Syndrome Death 11/6/2007 12 Male 4/25/2008 Physician Italy
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 11/1/2007 12 Male 5/6/2008 Physician Italy
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 4/25/2008 47 Female 172 lb 5/7/2008 Physician Germany
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 4/25/2008 47 Female 172 lb 5/19/2008 Physician Germany
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 4/25/2008 Female 5/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/25/2008 Female 5/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 4/25/2008 47 Female 172 lb 6/16/2008 Physician Germany
Primary
Secondary
Concomitant
Protein Total Decreased Hospitalization 4/25/2008 Female 6/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 5/11/2008 88 Female 7/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Nausea 6/1/2008 Female 160 lb 8/29/2008 United States
Primary
Concomitant
Drug Interaction Other Serious 8/5/2008 91 Female 132 lb 9/2/2008 Other Health Professional Portugal
Primary
Concomitant
Interacting
Drug Interaction Other Serious 8/5/2008 91 Female 132 lb 9/23/2008 Other Health Professional Portugal
Primary
Concomitant
Interacting
Drug Toxicity Hospitalization 66 Male 9/24/2008 Australia
Primary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/3/2008 United States
Primary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/6/2008 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 5/1/2007 59 Female 10/15/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Scleritis Disability 89 Female 10/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Scleritis Disability 89 Female 11/11/2008 United Kingdom
Primary
Concomitant
Nausea 6/1/2008 Female 160 lb 11/26/2008 United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/14/2009 28 Male 3/6/2009 Consumer Switzerland
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2000 56 Male 3/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urine Output Decreased Hospitalization 1/15/2009 65 Male 3/6/2009 Other Health Professional France
Primary
Concomitant
Urine Output Decreased Hospitalization 1/15/2009 65 Male 3/2/2009 United Kingdom
Primary
Concomitant
Urine Output Decreased Hospitalization 1/15/2009 65 Male 3/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 56 Male 3/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor 1/1/1998 Female 130 lb 3/12/2009 Consumer United States
Primary
Concomitant
Transaminases Increased Hospitalization 8/19/2008 75 Female 3/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Interaction 3/25/2009 Consumer United States
Primary
Secondary
Urine Output Decreased Other Serious 1/14/2009 Male 5/1/2009 Consumer Switzerland
Primary
Concomitant
Nerve Compression Hospitalization 3/1/2009 71 Male 5/1/2009 Pharmacist France
Primary
Concomitant
Nerve Compression Hospitalization 3/1/2009 71 Male 5/11/2009 Pharmacist France
Primary
Concomitant
Thrombin Time Shortened Other Serious 5/15/2009 Female 6/16/2009 Physician New Zealand
Primary
Concomitant
Pyrexia Hospitalization 1/22/2009 69 Female 6/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 11/3/2008 58 Female 221 lb 7/1/2009 Physician Germany
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 11/3/2008 58 Female 7/10/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 3/1/2009 71 Male 7/14/2009 Pharmacist France
Primary
Concomitant
Renal Impairment Other Serious Female 7/20/2009 Physician United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 227 lb 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 90 Male 8/21/2009 Japan
Primary
Secondary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2007 76 Male 128 lb 10/6/2009
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 9/11/2008 62 Male 174 lb 10/6/2009 Consumer United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 86 Female 12/7/2009 Denmark
Primary
Concomitant
Mental Disorder Hospitalization Male 12/18/2009 United Kingdom
Primary
Secondary
Concomitant
Post Procedural Infection Hospitalization Male 1/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mania Hospitalization 3/1/2009 Male 170 lb 2/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Lesion Other Serious 1/28/2010 57 Female 3/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/16/2009 90 Female 3/16/2010 Other Health Professional Australia
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/16/2009 90 Female 3/19/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 3/1/2009 71 Male 3/24/2010 Pharmacist France
Primary
Concomitant
Post Procedural Infection Hospitalization Male 4/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 8/19/2008 75 Female 143 lb 5/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Post Procedural Infection Hospitalization Male 5/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 8/19/2008 75 Female 5/14/2010 Physician France
Primary
Concomitant
Interacting
Circulatory Collapse Hospitalization 7/10/2003 83 Male 6/11/2010 Other Health Professional Sweden
Primary
Secondary
Renal Failure Other Serious 1/1/2009 Female 7/1/2010 Physician United States
Primary
Secondary
Concomitant
Failure To Thrive Hospitalization 3/27/2010 Female 7/12/2010 Other Health Professional United States
Primary
Concomitant
Constipation 9/1/2007 57 Male 294 lb 7/15/2010 Consumer United States
Primary
Concomitant
Eye Infection Other Serious 3/16/2010 82 Female 7/19/2010 Other Health Professional Switzerland
Primary
Concomitant
Suicidal Ideation Other Serious 94 Female 11/3/2010 Consumer United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 9/1/2010 94 Female 11/6/2010 United Kingdom
Primary
Concomitant
Failure To Thrive Hospitalization 3/27/2010 Female 11/30/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Bacterial Death 3/25/2010 58 Male 150 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 3/25/2010 58 Male 150 lb 12/29/2010 Physician Japan
Primary
Concomitant
Developmental Delay Hospitalization 3/27/2010 Female 1/12/2011 Other Health Professional United States
Primary
Concomitant
Delirium Other Serious 6/16/2010 53 Male 154 lb 4/8/2011 Physician Japan
Primary
Concomitant
Drug Interaction Life Threatening 11/8/2010 80 Female 143 lb 5/26/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 11/1/2009 72 Male 131 lb 6/29/2011 Physician Sweden
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 11/1/2009 72 Male 6/29/2011 Physician Sweden
Primary
Concomitant
Anticonvulsant Drug Level Decreased Hospitalization 58 Female 7/11/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Death 10/18/2005 66 Male 8/8/2011 Physician Germany
Primary
Secondary
Concomitant
Epilepsy Other Serious 2/23/2006 59 Male 267 lb 8/11/2011 Physician Germany
Primary
Concomitant
Drug Effect Increased Life Threatening 11/8/2010 80 Female 143 lb 8/12/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 67 Female 8/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Dysfunction Hospitalization 6/1/2011 43 Female 8/29/2011 Physician United Kingdom
Primary
Concomitant
Fallot's Tetralogy Other Serious 43 8/29/2011 Physician United Kingdom
Primary
Concomitant
Torsade De Pointes Hospitalization 67 Female 9/8/2011 Physician United Kingdom
Primary
Secondary
Hypertension Other Serious 6/12/2010 53 Male 154 lb 10/5/2011 Physician Japan
Primary
Concomitant
Hyponatraemia Hospitalization 10/16/2001 81 Male 10/7/2011 Consumer France
Primary
Secondary
Dyspepsia Hospitalization 10/3/2011 84 Female 119 lb 10/24/2011 Physician Australia
Primary
Concomitant
Urinary Tract Infection Hospitalization Male 12/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epilepsy Hospitalization 9/20/2011 67 Male 99 lb 12/6/2011 Other Health Professional Germany
Primary
Concomitant
Disease Progression Death 9/1/2011 23 Male 53 lb 12/19/2011 Consumer United States
Primary
Concomitant
Acute Prerenal Failure Hospitalization 76 Male 12/19/2011 Physician Japan
Primary
Secondary
Concomitant
Arrhythmia Death 62 Male 12/16/2011 Physician Turkey
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 134 lb 12/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chromaturia Hospitalization 11/4/2010 35 Male 12/28/2011 Other Health Professional China
Primary
Concomitant
Schizophrenia Hospitalization 1/1/2011 43 Female 12/28/2011 Pharmacist Australia
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 134 lb 12/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 1/1/2011 32 Male 134 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 134 lb 12/22/2011 Other Health Professional
Primary
Secondary
Concomitant
Blood Pressure Decreased Hospitalization 76 Male 12/27/2011 Physician Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 61 lb 12/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 76 Male 1/6/2012 Other Health Professional France
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 11/4/2010 35 Male 1/9/2012 Other Health Professional China
Primary
Concomitant
Antipsychotic Drug Level Below Therapeutic Hospitalization 12/7/2011 44 Female 1/17/2012 Physician Australia
Primary
Concomitant
Death Death Male 162 lb 1/25/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 11/4/2010 35 Male 97 lb 1/26/2012 Pharmacist China
Primary
Concomitant
Blood Bilirubin Unconjugated Increased Hospitalization 11/4/2010 35 Male 97 lb 1/30/2012 Pharmacist China
Primary
Concomitant
Death Death 10/10/2011 88 Male 2/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hypocalcaemia Death 4/25/2008 47 Female 2/2/2012 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/24/2011 71 Male 3/5/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 12/26/2011 71 Male 3/6/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Gouty Arthritis Hospitalization 8/19/2011 55 Male 121 lb 3/9/2012 Physician Thailand
Primary
Secondary
Concomitant
Nausea Other Serious 6/12/2010 53 Male 154 lb 3/15/2012 Physician Japan
Primary
Concomitant
Pulmonary Embolism Death 2/17/2012 51 Female 3/15/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Urea Increased Other Serious 76 Male 3/22/2012 Consumer France
Primary
Secondary
Concomitant
Thrombocytopenia Death 2/16/2012 81 Female 4/26/2012 Other Health Professional France
Primary
Secondary
Concomitant
Hyperprolactinaemia Other Serious 53 Female 5/23/2012 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Dry Eye Other Serious 6/12/2010 53 Male 154 lb 5/30/2012 Physician Japan
Primary
Concomitant

Drug Data