Furosemide combined with Ursodiol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure 7/24/2004 54 Male 1/24/2006 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 5/25/2005 50 Male 218 lb 4/17/2006 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 5/25/2005 50 Male 218 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 3/25/2006 Male 6/5/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 10/19/2006 54 Female 2/21/2007 Japan
Primary
Secondary
Concomitant
Varices Oesophageal Death 3/22/2006 Male 4/3/2007 United Kingdom
Primary
Concomitant
Hepatitis Other Serious 2/15/2007 Female 4/17/2007 Physician Germany
Primary
Secondary
Hepatitis Other Serious 2/15/2007 64 Female 238 lb 4/24/2007 Physician Germany
Primary
Concomitant
Renal Impairment Other Serious 3/29/2007 69 Male 135 lb 9/21/2007 Other Health Professional Japan
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 6/1/2006 86 Male 131 lb 10/6/2007 Japan
Primary
Concomitant
Somnolence Other Serious 1/1/2007 8 Male 88 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 1/1/2007 8 Male 88 lb 10/31/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 8/18/2007 8 Male 88 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/17/2004 57 Female 171 lb 11/26/2007 Physician United States
Primary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 11/1/2007 Female 130 lb 11/30/2007 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/17/2004 57 Female 171 lb 2/22/2008 Other Health Professional United States
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 4/8/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 4/16/2006 29 Male 140 lb 4/8/2008 United States
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 4/22/2008 Physician Japan
Primary
Concomitant
Erectile Dysfunction 2/19/2007 56 Male 4/23/2007 Consumer United States
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 5/1/2008 Physician Japan
Primary
Concomitant
Urinary Incontinence Death 45 Male 5/1/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 3/3/2008 Female 148 lb 5/28/2008 Physician Belgium
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 7/3/2008 Physician Japan
Primary
Concomitant
Sepsis Other Serious 3/3/2008 Female 148 lb 7/10/2008 Physician Belgium
Primary
Concomitant
Blood Count Abnormal Hospitalization Male 7/11/2008 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 6/1/2008 Female 106 lb 7/16/2008 Physician Denmark
Primary
Concomitant
Stem Cell Transplant Hospitalization 5/12/2008 60 Female 200 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Blood Albumin Decreased Other Serious Male 7/21/2008 United States
Primary
Concomitant
Blood Count Abnormal Hospitalization Male 8/11/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2008 Female 90 lb 10/15/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/5/2008 11/14/2008 Consumer Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 10/14/2008 Male 95 lb 11/18/2008 Physician Japan
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 10/21/2008 56 Male 191 lb 11/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 10/14/2008 Male 95 lb 12/2/2008 Physician Japan
Primary
Secondary
Concomitant
Portal Vein Thrombosis Hospitalization 8/14/2008 12/24/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 11/1/2007 Female 130 lb 1/8/2009 Consumer United States
Primary
Secondary
Concomitant
Swelling Other Serious 11/1/2007 Female 130 lb 1/22/2009 Physician United States
Primary
Secondary
Concomitant
Portal Vein Thrombosis Hospitalization 8/14/2008 2/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 1/1/2009 Female 110 lb 2/17/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2003 0 Male 13 lb 3/19/2009 France
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Other Serious 12/1/2008 57 Male 119 lb 4/24/2009 Physician Germany
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 4/9/2009 Male 56 lb 5/27/2009 United States
Primary
Concomitant
Injection Site Rash 1/22/2009 19 Female 135 lb 5/15/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 3/30/2009 66 Male 6/16/2009 Physician Italy
Primary
Concomitant
Cardiac Failure Chronic Hospitalization 8/24/2004 67 Female 106 lb 6/29/2009 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/22/2006 69 Female 110 lb 7/2/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/30/2009 66 Male 7/22/2009 Physician Italy
Primary
Concomitant
Anaphylactoid Reaction Other Serious 6/18/2009 71 Male 7/22/2009 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/31/2008 47 Male 7/31/2009 Japan
Primary
Concomitant
Anaphylactoid Reaction Other Serious 6/18/2009 71 Male 8/11/2009 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 8/18/2009 Male 111 lb 9/8/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 8/18/2009 Male 111 lb 9/22/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/29/2007 69 Male 135 lb 9/17/2009 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 5/21/2009 71 Male 137 lb 9/29/2009 Korea, Republic Of
Primary
Concomitant
Weight Increased Other Serious 10/1/2008 Male 198 lb 10/2/2009 United States
Primary
Concomitant
Epistaxis Other Serious 6/5/2008 47 Male 10/9/2009 Physician Japan
Primary
Concomitant
Periodontitis Hospitalization 32 146 lb 10/29/2009 Physician Germany
Primary
Concomitant
Periodontitis Hospitalization 32 146 lb 11/2/2009 Physician Germany
Primary
Concomitant
Death Death 2/2/2010 Female 137 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 Female 200 lb 3/23/2010 Consumer United States
Primary
Concomitant
Death Death 2/2/2010 81 Female 137 lb 4/1/2010 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 7/30/2009 53 Male 207 lb 4/6/2010 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 7/30/2009 53 Male 207 lb 4/7/2010 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious 8/5/2003 68 Female 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 7/30/2009 53 Male 207 lb 4/23/2010 Physician United States
Primary
Concomitant
Large Intestine Carcinoma Other Serious 70 Male 137 lb 5/17/2010 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 7/1/2009 67 Female 5/19/2010 Consumer United States
Primary
Secondary
Concomitant
Large Intestine Carcinoma Hospitalization 70 Male 137 lb 5/21/2010 Physician Japan
Primary
Concomitant
Large Intestine Carcinoma Hospitalization 70 Male 137 lb 5/26/2010 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 7/30/2009 53 Male 207 lb 6/4/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 64 Female 200 lb 6/3/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Large Intestine Carcinoma Hospitalization 70 Male 137 lb 6/9/2010 Physician Japan
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/13/2009 54 Male 161 lb 6/11/2010 Japan
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 176 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Panic Disorder Other Serious 5/20/2008 75 Female 170 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 3/7/2006 69 Female 110 lb 6/30/2010 Physician Japan
Primary
Concomitant
Panic Disorder Other Serious 5/20/2008 75 Female 170 lb 7/7/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Condition Aggravated Hospitalization 8/24/2004 67 Female 106 lb 7/7/2010 Physician Japan
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/21/2010 Other Health Professional United States
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/13/2009 54 Male 161 lb 7/26/2010 Japan
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/25/2010 64 Male 288 lb 8/10/2010 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 66 Male 119 lb 8/10/2010 Consumer Japan
Primary
Secondary
Visual Impairment Other Serious 1/1/2010 64 Male 300 lb 8/16/2010 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/31/2010 9 Female 59 lb 8/13/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Hospitalization 5/3/2010 2 Male 8/16/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/25/2010 64 Male 288 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 4/30/2010 32 Female 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/13/2009 4 Female 31 lb 9/9/2010 Physician Japan
Primary
Concomitant
Venous Thrombosis Other Serious 8/5/2003 68 Female 9/24/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/25/2010 64 Male 288 lb 10/13/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 2/8/2010 15 Female 110 lb 10/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2004 45 Female 224 lb 10/21/2010 United States
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 3/15/2009 38 Male 128 lb 9/30/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 63 Male 126 lb 10/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 10/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/17/2010 77 Male 134 lb 11/1/2010 Physician Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/17/2010 77 Male 134 lb 11/9/2010 Physician Japan
Primary
Concomitant
Venous Thrombosis Other Serious 8/5/2003 68 Female 11/18/2010 United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 8/3/2009 62 Female 110 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 5/26/2010 Male 18 lb 11/24/2010 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/24/2009 49 Female 237 lb 10/26/2010 Other Health Professional Australia
Primary
Concomitant
Vomiting Hospitalization 4/8/2010 Female 12/2/2010 Consumer China
Primary
Concomitant
Urticaria Hospitalization 6/24/2010 44 Female 12/1/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 12/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 9/22/2010 78 Male 160 lb 12/15/2010 Physician Japan
Primary
Concomitant
Hernia Hospitalization 1/26/2010 55 Male 12/9/2010 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 7/28/2010 30 Female 99 lb 1/6/2011 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Haemorrhage Death 4/13/2009 4 Female 31 lb 1/7/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 7/13/2009 54 Male 161 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 7/13/2009 54 Male 161 lb 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 10/22/2010 54 Male 176 lb 1/21/2011 Physician Japan
Primary
Concomitant
Seroma Other Serious 1/14/2010 55 Male 201 lb 1/14/2011 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 12/1/2010 74 Female 101 lb 2/3/2011 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 12/17/2010 74 Female 101 lb 2/10/2011 Physician Japan
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 45 Female 224 lb 2/11/2011 United States
Primary
Concomitant
Dysfunctional Uterine Bleeding Other Serious 1/1/2004 45 Female 224 lb 2/18/2011 United States
Primary
Concomitant
Drug Ineffective Hospitalization 7/3/2008 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Other Serious 8/9/2007 72 Female 2/24/2011 United States
Primary
Secondary
Concomitant
Hepatosplenomegaly Death 1/27/2011 68 Male 2/15/2011 Other Health Professional United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 42 Female 2/21/2011 Other Health Professional Netherlands
Primary
Concomitant
Bacterial Test Positive Other Serious 11/20/2010 57 Female 3/11/2011 Other Health Professional United States
Primary
Concomitant
Fungal Infection Other Serious 8/6/2010 60 Male 132 lb 3/14/2011 Other Health Professional Italy
Primary
Concomitant

Drug Data