Furosemide combined with Sorafenib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Hospitalization 2/7/2006 76 Male 176 lb 3/13/2006 Poland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 3/28/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/7/2006 76 Male 176 lb 4/7/2006 Poland
Primary
Concomitant
Tachycardia Hospitalization 4/20/2006 74 Female 167 lb 5/2/2006 Sweden
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 2/7/2006 76 Male 176 lb 5/11/2006 Poland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/18/2006 80 Male 176 lb 7/5/2006 Poland
Primary
Concomitant
Vomiting Hospitalization 5/10/2006 47 Female 136 lb 7/5/2006 Australia
Primary
Concomitant
Vomiting Other Serious 7/7/2006 52 Female 159 lb 7/27/2006 Spain
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Physician Canada
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Canada
Primary
Concomitant
Haemoptysis Hospitalization 1/1/2006 65 Male 146 lb 8/17/2006 Physician Denmark
Primary
Concomitant
Vomiting Other Serious 6/16/2006 53 Female 159 lb 9/12/2006 Physician Spain
Primary
Concomitant
Weight Decreased Life Threatening 5/4/2006 52 Male 130 lb 9/26/2006 Physician Poland
Primary
Concomitant
Neutropenia Hospitalization 2/8/2006 59 Male 225 lb 9/26/2006 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 9/8/2006 63 Male 159 lb 9/27/2006 United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 9/8/2006 63 Male 159 lb 10/4/2006 United Kingdom
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 4/1/2006 65 Male 146 lb 10/19/2006 Physician Denmark
Primary
Concomitant
Renal Failure Other Serious 1/18/2006 80 Male 176 lb 11/1/2006 Physician Poland
Primary
Concomitant
Urinary Retention Hospitalization 9/8/2006 63 Male 159 lb 11/2/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/4/2006 52 Male 130 lb 11/13/2006 Physician Poland
Primary
Concomitant
Vith Nerve Paralysis Hospitalization 5/10/2006 47 Female 137 lb 11/21/2006 Physician Australia
Primary
Concomitant
Malignant Melanoma Hospitalization 5/10/2006 47 Female 137 lb 11/27/2006 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 9/8/2006 63 Male 159 lb 11/28/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 12/21/2006 Physician Canada
Primary
Concomitant
Therapy Non-responder Hospitalization 12/14/2006 87 Male 178 lb 12/18/2006 Pharmacist United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 12/1/2006 58 Male 157 lb 1/3/2007 Physician Korea, Republic Of
Primary
Concomitant
Hyperthyroidism Hospitalization 2/17/2006 72 Male 183 lb 1/15/2007 Physician France
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 3/13/2007 71 Male 148 lb 3/30/2007 Physician Spain
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 3/13/2007 71 Male 148 lb 4/3/2007 Physician Spain
Primary
Secondary
Concomitant
Rash Life Threatening 1/24/2007 61 Male 126 lb 4/5/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Tumour Embolism Hospitalization 3/13/2007 71 Male 148 lb 4/17/2007 Physician Spain
Primary
Secondary
Concomitant
Syncope Other Serious 6/16/2006 53 Female 159 lb 6/21/2007 Physician Spain
Primary
Concomitant
Syncope Other Serious 4/30/2007 72 Male 75 lb 6/22/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 5/11/2007 49 Female 148 lb 7/12/2007 Physician Germany
Primary
Concomitant
Syncope Other Serious 4/30/2007 72 Male 75 lb 7/11/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 5/11/2007 49 Female 148 lb 7/18/2007 Physician Germany
Primary
Concomitant
Syncope Other Serious 4/30/2007 72 Male 75 lb 7/27/2007 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 4/30/2007 72 Male 163 lb 9/10/2007 Physician United Kingdom
Primary
Concomitant
Scrotal Ulcer Hospitalization 9/25/2007 75 Male 10/15/2007 Physician Italy
Primary
Concomitant
Pruritus 1/1/2005 45 Female 10/12/2007 Consumer United States
Primary
Concomitant
Scrotal Ulcer Hospitalization 9/25/2007 75 Male 11/19/2007 Physician Italy
Primary
Concomitant
Syncope Hospitalization 3/28/2007 72 Male 163 lb 12/12/2007 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 75 Male 163 lb 1/29/2008 Netherlands
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/15/2006 59 Male 225 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Scrotal Ulcer Hospitalization 9/25/2007 75 Male 2/12/2008 Physician Italy
Primary
Concomitant
Metabolic Acidosis Hospitalization 3/17/2008 75 Male 3/31/2008 Physician United States
Primary
Secondary
Concomitant
Rash Life Threatening 1/24/2007 61 Male 126 lb 4/23/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/17/2008 75 Male 5/14/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 3/28/2007 72 Male 163 lb 4/9/2008 Physician Germany
Primary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 2/20/2008 62 Male 8/21/2008 Physician France
Primary
Secondary
Concomitant
Cardiac Tamponade Hospitalization Male 154 lb 10/8/2008 Physician Poland
Primary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Tamponade Life Threatening 6/13/2007 56 Male 154 lb 1/8/2009 Physician Poland
Primary
Concomitant
Atrial Flutter Hospitalization 1/20/2009 67 Male 209 lb 2/12/2009 Physician Italy
Primary
Concomitant
Rash Life Threatening 1/24/2007 61 Male 126 lb 5/26/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Rash Life Threatening 1/24/2007 61 Male 126 lb 5/27/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Fall Hospitalization 4/17/2009 69 Male 176 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 4/17/2009 69 Male 176 lb 7/6/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 4/17/2009 69 Male 176 lb 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Diarrhoea 65 Female 8/25/2009 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2009 55 Male 10/6/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Speech Disorder Hospitalization 9/10/2009 62 Male 273 lb 11/13/2009 Physician Netherlands
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 10/1/2007 70 Male 12/14/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Wound Dehiscence Other Serious 1/1/2007 Male 1/12/2010 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 12/11/2009 58 Male 1/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 12/28/2009 81 Male 141 lb 1/28/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Thrombocytopenia Other Serious 62 Male 1/29/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 62 Male 2/1/2010 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/5/2010 Physician United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 1/23/2010 48 Female 134 lb 2/9/2010 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/11/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/18/2010 Physician United States
Primary
Concomitant
Peritoneal Disorder Hospitalization 1/23/2010 48 Female 134 lb 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/26/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/2/2010 Physician United States
Primary
Concomitant
Myalgia Hospitalization 70 Male 3/11/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/11/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/18/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 70 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 70 Male 3/24/2010 Pharmacist United States
Primary
Concomitant
Interacting
Mucosal Inflammation Life Threatening 2/15/2010 71 Male 132 lb 3/30/2010 Italy
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/30/2010 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 2/20/2010 68 Male 132 lb 5/11/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2010 68 Male 207 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 5/8/2010 69 Male 5/21/2010 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2010 68 Male 207 lb 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 5/8/2010 69 Male 5/25/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/11/2009 58 Male 5/26/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 5/8/2010 69 Male 6/24/2010 Canada
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 6/15/2010 67 Male 170 lb 7/7/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/11/2009 58 Male 7/15/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Hepatic Encephalopathy Other Serious 2/20/2010 68 Male 132 lb 8/2/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Nausea Hospitalization 7/6/2010 56 Male 9/8/2010 Physician Australia
Primary
Secondary
Concomitant
Acute Hepatic Failure Death 5/31/2010 68 Female 117 lb 9/22/2010 Spain
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 56 Female 185 lb 9/23/2010 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 8/23/2010 69 Male 9/24/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 5/8/2010 69 Male 9/29/2010 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/9/2008 61 Female 108 lb 10/4/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 6/15/2010 67 Male 170 lb 10/15/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Renal Impairment Hospitalization 4/9/2008 61 Female 108 lb 10/18/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/20/2010 57 Male 119 lb 11/8/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/20/2010 57 Male 119 lb 11/18/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Lethargy Hospitalization 11/17/2010 79 Male 216 lb 11/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 12/4/2008 60 Male 11/24/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/23/2010 69 Male 11/17/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Anaemia Hospitalization 7/19/2010 60 Male 209 lb 12/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Death 5/31/2010 68 Female 117 lb 2/8/2011 Physician Spain
Primary
Concomitant
Hepatitis Fulminant Death 5/26/2010 68 Female 117 lb 3/30/2011 Physician Spain
Primary
Concomitant
Gangrene Death 1/18/2010 65 Male 4/19/2011 Physician United States
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 10/18/2010 55 Male 139 lb 5/11/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Anaemia Hospitalization 7/19/2010 60 Male 209 lb 5/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Encephalopathy Disability 9/2/2010 75 Male 117 lb 6/13/2011 Physician Portugal
Primary
Concomitant
Hepatic Neoplasm Malignant Disability 65 Male 6/29/2011 Consumer United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 5/1/2010 78 Male 174 lb 7/18/2011 Consumer Germany
Primary
Concomitant
Lethargy Hospitalization 11/17/2010 78 Male 215 lb 8/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Death 11/12/2010 45 Male 115 lb 9/14/2011 Physician New Zealand
Primary
Secondary
Concomitant
Chest Pain Death 11/12/2010 45 Male 115 lb 9/16/2011 Physician New Zealand
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 11/11/2011 Consumer United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 11/11/2011 72 Male 265 lb 11/11/2011 United States
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 11/24/2011 United States
Primary
Secondary
Concomitant
Off Label Use Death 11/11/2011 Male 265 lb 11/28/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 12/2/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 11/11/2011 72 Male 225 lb 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 11/11/2011 72 Male 225 lb 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Fatigue Death 5/26/2010 68 Female 117 lb 12/27/2011 Physician Spain
Primary
Concomitant
Asthenia Death 5/26/2010 68 Female 117 lb 1/13/2012 Physician Spain
Primary
Concomitant
Asthenia Other Serious 80 Male 161 lb 2/3/2012 Other Health Professional France
Primary
Concomitant
Interacting
Anaemia Other Serious 10/11/2011 69 Male 123 lb 2/21/2012 Physician Brazil
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 2/6/2012 66 Male 190 lb 3/2/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 5/5/2011 64 Male 190 lb 3/2/2012 Physician Germany
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 10/11/2011 69 Male 123 lb 3/5/2012 Physician Brazil
Primary
Secondary
Concomitant
Metastases To Abdominal Cavity Hospitalization 2/6/2012 66 Male 190 lb 3/9/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Hospitalization 1/28/2010 69 Male 161 lb 3/27/2012 Physician France
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 2/6/2012 65 Male 190 lb 3/28/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Epistaxis Hospitalization 5/5/2011 64 Male 190 lb 3/28/2012 Physician Germany
Primary
Secondary
Concomitant
Skin Haemorrhage Hospitalization 3/17/2010 69 Male 291 lb 4/3/2012 Physician Austria
Primary
Concomitant
Skin Haemorrhage Hospitalization 3/17/2010 69 Male 291 lb 4/10/2012 Physician Austria
Primary
Concomitant
Dyspnoea Other Serious 5/5/2011 64 Male 190 lb 4/9/2012 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 5/5/2011 64 Male 190 lb 4/24/2012 Physician Germany
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 5/5/2011 64 Male 190 lb 5/9/2012 Physician Germany
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 6/15/2010 67 Male 170 lb 5/17/2012 Other Health Professional Korea, Republic Of
Primary
Concomitant
Haemorrhagic Anaemia Other Serious 5/5/2011 64 Male 203 lb 5/31/2012 Physician Germany
Primary
Secondary
Concomitant
Metastases To Abdominal Cavity Hospitalization 2/6/2012 65 Male 185 lb 6/1/2012 Other Health Professional Germany
Primary
Secondary
Concomitant

Drug Data