Furosemide combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Extrasystoles Other Serious 12/1/2005 Male 1/20/2006 Physician Sweden
Primary
Concomitant
Weight Increased Other Serious 10/1/2005 59 Male 198 lb 1/24/2006 Pharmacist Spain
Primary
Concomitant
Yellow Skin Other Serious 12/28/2002 63 Male 1/30/2006 Physician Philippines
Primary
Concomitant
Kidney Transplant Rejection Other Serious 6/7/2005 50 Female 2/7/2006 Brazil
Primary
Concomitant
Rash Hospitalization 1/12/2006 Female 117 lb 2/15/2006 Physician Portugal
Primary
Concomitant
Renal Failure Hospitalization 2/21/2006 75 Female 150 lb 3/14/2006 Physician Italy
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 82 Male 4/6/2006 Japan
Primary
Concomitant
Peritonitis Life Threatening 3/19/1998 0 Female 2 lb 4/11/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 4/24/2006 Consumer Ireland
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 5/8/2006 Physician Sweden
Primary
Concomitant
Bundle Branch Block Right Hospitalization 4/26/2006 69 Male 225 lb 5/8/2006 Other Health Professional Germany
Primary
Concomitant
Peritonitis Life Threatening 3/19/1998 0 Female 2 lb 5/12/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/20/2005 76 Female 170 lb 5/8/2006 Physician Austria
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 5/8/2006 Female 161 lb 5/24/2006 Physician Germany
Primary
Concomitant
Infection Life Threatening 4/29/2006 15 Female 5/30/2006 Physician Netherlands
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 12/1/2005 Male 6/6/2006 Physician Sweden
Primary
Concomitant
Ventricular Tachycardia Required Intervention 5/6/2006 54 Male 143 lb 5/31/2006 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 82 Male 6/8/2006 Other Health Professional Japan
Primary
Concomitant
Skin Irritation Other Serious 7/22/2005 0 Male 6/6/2006 Japan
Primary
Concomitant
Skin Irritation Other Serious 11/2/2004 0 Female 6/14/2006 Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/2/2006 66 198 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 4/29/2006 15 Female 7/31/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/26/2005 52 Female 7/24/2006 United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 7/17/2006 Female 8/9/2006 Physician Australia
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 8/21/2006 Physician Sweden
Primary
Concomitant
Haemoglobin Increased Other Serious 7/17/2006 Female 9/7/2006 Physician Australia
Primary
Concomitant
Respiratory Distress Disability 5/8/2006 67 Male 9/12/2006 Norway
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/30/2006 59 Male 9/26/2006 Japan
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 10/11/2006 83 Male 158 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Small Intestinal Perforation Life Threatening 3/11/1998 0 Female 2 lb 10/19/2006 Physician Japan
Primary
Secondary
Concomitant
Oedema Hospitalization 6/7/2006 58 Male 11/10/2006 United Kingdom
Primary
Concomitant
Purulent Discharge Required Intervention 9/30/2006 60 Male 205 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Hospitalization 11/22/2006 67 Male 12/15/2006 Physician Japan
Primary
Secondary
Concomitant
Dizziness 71 Male 12/28/2006 Consumer United States
Primary
Concomitant
Multi-organ Failure Hospitalization 11/15/2006 54 Male 276 lb 12/29/2006 Pharmacist United States
Primary
Concomitant
Renal Disorder Other Serious 8/1/2006 Female 1/8/2007 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 1/8/2007 Consumer Ireland
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 11/22/2006 67 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 1/1/2007 45 Male 1/19/2007 Chile
Primary
Concomitant
Renal Disorder Other Serious 8/1/2006 Female 1/22/2007 Physician Germany
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 2/2/2007 Consumer Ireland
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 1/1/2004 Female 137 lb 2/5/2007 Physician Germany
Primary
Concomitant
Respiratory Disorder Hospitalization 11/21/2006 67 Male 1/26/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Death 1/1/2007 45 Male 2/8/2007 Chile
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 2/20/2007 Consumer Ireland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/25/2007 83 Female 2/23/2007 Physician Czech Republic
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 3/7/2007 Korea, Republic Of
Primary
Concomitant
Tremor Other Serious 60 Male 3/16/2007 Consumer Sweden
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 3/19/2007 Korea, Republic Of
Primary
Concomitant
Nephritis Interstitial Other Serious 4/29/2005 Female 208 lb 3/23/2007 Physician Brazil
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/7/2007 Male 170 lb 3/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 4/2/2007 Korea, Republic Of
Primary
Concomitant
Tremor Other Serious 60 Male 4/20/2007 Consumer Sweden
Primary
Concomitant
Renal Failure Chronic Hospitalization 4/13/2007 72 Male 152 lb 5/18/2007 Physician Japan
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/5/2005 12/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ileal Perforation Other Serious 3/18/2006 0 Male 3/28/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious Male 217 lb 5/31/2007 Physician Sweden
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 4/13/2007 72 Male 152 lb 6/1/2007 Physician Japan
Primary
Concomitant
Psychiatric Symptom Hospitalization 6/1/2007 62 Female 97 lb 6/11/2007 Pharmacist Japan
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 2/1/2004 71 Male 180 lb 6/12/2007 Other Health Professional United States
Primary
Concomitant
Psychiatric Symptom 6/1/2007 62 Female 97 lb 6/18/2007 Pharmacist Japan
Primary
Concomitant
Deafness Neurosensory Disability 10/1/2002 5 Female 6/12/2007 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/22/2006 50 Male 6/25/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Death 5/30/2007 63 Female 95 lb 6/27/2007 Physician Thailand
Primary
Concomitant
Psychiatric Symptom 6/1/2007 62 Female 97 lb 7/3/2007 Pharmacist Japan
Primary
Concomitant
Nausea Female 4/10/2007 Consumer United States
Primary
Concomitant
Toxic Encephalopathy 6/1/2007 62 Female 97 lb 7/9/2007 Pharmacist Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 7/13/2007 Consumer Ireland
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 8/1/2007 Consumer Ireland
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 2/19/2006 60 Male 8/15/2007 Consumer Ireland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/17/2007 60 Male 208 lb 8/21/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 8/30/2007 Korea, Republic Of
Primary
Concomitant
Stupor Hospitalization 8/9/2007 51 Female 84 lb 9/4/2007 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious Male 217 lb 9/6/2007 Consumer Sweden
Primary
Secondary
Concomitant
Stupor Hospitalization 8/9/2007 51 Female 84 lb 9/7/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/1/2007 60 Male 212 lb 9/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Stupor Hospitalization 8/9/2007 51 Female 84 lb 9/17/2007 Physician Japan
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 8/1/2007 Female 196 lb 9/20/2007 Physician Germany
Primary
Concomitant
Staphylococcal Sepsis Death 9/10/2007 69 Male 9/19/2007 Physician Slovenia
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 2/1/2004 71 Male 180 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Dyspnoea Life Threatening 6/8/2007 53 Female 169 lb 10/4/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 10/1/2007 Male 183 lb 11/9/2007 Turkey
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 11/27/2007 Consumer Ireland
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/19/2006 60 Male 2/1/2008 Consumer Ireland
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/19/2008 Male 133 lb 1/29/2008 United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2008 Female 2/9/2008 Physician Germany
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/12/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/1/2007 60 Male 212 lb 2/13/2008 Other Health Professional France
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/13/2008 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/25/2008 Female 152 lb 2/14/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Death 12/7/2005 64 Male 200 lb 2/11/2008 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/30/2007 60 Male 212 lb 3/6/2008 Other Health Professional France
Primary
Secondary
Concomitant
Necrotising Enterocolitis Neonatal Required Intervention 1/22/2008 0 Male 2 lb 2/29/2008 Physician Belgium
Primary
Concomitant
Bronchiectasis Hospitalization 3/1/2006 36 Female 130 lb 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/30/2007 60 Male 212 lb 3/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/1/2007 60 Male 212 lb 3/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Tumour Lysis Syndrome Other Serious 6/25/2007 55 Female 90 lb 3/31/2008 Physician Japan
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 8/20/2007 Male 4/17/2008 Physician Sweden
Primary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/22/2008 Physician Japan
Primary
Concomitant
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/7/2008 Sweden
Primary
Concomitant
Drug Interaction Other Serious 4/1/2007 47 Male 5/12/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Interacting
Ventricular Tachycardia Other Serious 11 Male 5/13/2008
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/13/2008 Sweden
Primary
Concomitant
Erythropoiesis Abnormal Other Serious 47 Male 5/8/2008 Italy
Primary
Secondary
Concomitant
Chest Pain Life Threatening 5/8/2008 63 Male 5/14/2008 Sweden
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 8/20/2007 Male 5/20/2008 Physician Sweden
Primary
Concomitant
Impaired Work Ability Life Threatening 2/1/2008 63 Male 128 lb 6/5/2008 Sweden
Primary
Concomitant
Multi-organ Failure Hospitalization 5/2/2008 Male 6/9/2008 Physician Switzerland
Primary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 60 Male 5/30/2008 Physician Sweden
Primary
Concomitant
Orthopnoea Hospitalization 66 Female 6/18/2008 Consumer Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 6/26/2008 Physician Japan
Primary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 7/15/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 6/1/2008 73 Female 7/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 8/3/2008 63 Male 8/8/2008 Sweden
Primary
Concomitant
Presyncope Other Serious 6/1/2008 63 Male 131 lb 8/11/2008 Sweden
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 8/22/2008 Korea, Republic Of
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 8/27/2008 Sweden
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 133 lb 9/9/2008 Sweden
Primary
Concomitant
Palpitations Other Serious Male 8/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Splenic Necrosis Death Male 9/26/2008 Other Health Professional Norway
Primary
Concomitant
Splenic Necrosis Death 62 Male 10/3/2008 Other Health Professional Norway
Primary
Concomitant
Endocarditis Death 5/10/2007 69 Male 10/1/2008 Physician Slovenia
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 86 Female 10/8/2008
Primary
Secondary
Concomitant
Nasopharyngitis Hospitalization 9/14/2008 42 Male 10/9/2008 Sweden
Primary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tongue Oedema Hospitalization 1/25/2008 Female 152 lb 10/27/2008 Physician United States
Primary
Concomitant
Procedural Complication Life Threatening 2/8/2008 18 Female 99 lb 11/26/2008 United States
Primary
Secondary

Drug Data