Furosemide combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Vomiting Other Serious 11/30/2005 85 Female 143 lb 12/9/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/11/2006 Female 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Psychomotor Retardation Hospitalization 4/9/2002 72 Female 3/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hiatus Hernia Hospitalization 9/6/2005 Female 139 lb 3/14/2006 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 72 Female 251 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 2/22/2006 85 Female 153 lb 2/22/2006 Pharmacist United States
Primary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/13/2006 80 Female 154 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Drug Toxicity Hospitalization 1/10/2006 69 Female 99 lb 5/10/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/21/2006 57 Male Pharmacist United States
Primary
Secondary
Concomitant
Rash Vesicular Hospitalization 4/10/2006 76 Female 8/21/2006 Pharmacist United States
Primary
Concomitant
Eczema Other Serious 96 Male 8/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Reproductive Tract Disorder Other Serious 8/30/2006 31 Female 9/8/2006 Pharmacist United States
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 9/1/2006 63 Male 249 lb 9/6/2006 Pharmacist United States
Primary
Concomitant
Wound Secretion Other Serious 9/8/2006 80 Male 152 lb 9/22/2006 Other Health Professional United States
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 9/8/2006 80 Male 335 lb 10/6/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 9/9/2004 55 Female 10/20/2006 United States
Primary
Concomitant
Urine Ketone Body Present Other Serious 12/1/2005 Female 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Hospitalization 11/1/2006 79 Female 1/4/2007 Physician France
Primary
Concomitant
Convulsion Other Serious 11/1/2006 79 Female 1/12/2007 Other Health Professional France
Primary
Concomitant
Swollen Tongue Other Serious 12/27/2006 89 Female 1/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 12/27/2006 89 Female 2/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/1/2006 68 Male 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 9/8/2006 80 Male 152 lb 3/9/2007 Other Health Professional United States
Primary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/15/2007 77 Female 190 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Fluid Retention 11/17/2006 50 Female 162 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 7/1/2005 61 Female 198 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/2/2006 82 Female 4/4/2007 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 35 Female 4/27/2007 Netherlands
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 39 Female 5/11/2007 Other Health Professional Japan
Primary
Secondary
Throat Irritation Other Serious 1/1/2003 54 Female 5/25/2007 United States
Primary
Concomitant
Skin Haemorrhage Life Threatening 12/15/2006 69 Male 7/16/2007 Other Health Professional Denmark
Primary
Concomitant
Skin Haemorrhage Life Threatening 12/15/2006 Male 7/23/2007 Other Health Professional Denmark
Primary
Concomitant
Throat Irritation Other Serious 1/1/2003 54 Female 8/11/2007 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 12/12/2007 66 Male 143 lb 12/19/2007 India
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 11/10/2003 80 Female 1/21/2008 Physician Germany
Primary
Secondary
Vaginal Candidiasis Hospitalization 11/13/2007 61 Female 170 lb 1/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Required Intervention 3/13/2007 70 Female 1/24/2008 Other Health Professional United States
Primary
Concomitant
Hepatitis Cholestatic Death 11/16/2007 55 Female 2/27/2008 Physician Spain
Primary
Secondary
Skin Papilloma Other Serious 1/26/2007 30 Female 4/28/2008 Physician France
Primary
Concomitant
Transaminases Increased Hospitalization 9/3/2007 72 Female 5/16/2008 Other Health Professional Singapore
Primary
Concomitant
Pyrexia Death 45 Male 5/19/2008 Canada
Primary
Secondary
Pulmonary Thrombosis Death 1/1/2004 45 Male 5/19/2008 Canada
Primary
Secondary
Respiratory Distress Hospitalization 4/29/2008 Male 260 lb 5/27/2008 Physician United States
Primary
Concomitant
Muscular Weakness 4/27/2008 Female 238 lb 6/13/2008 United States
Primary
Concomitant
Vulvovaginal Candidiasis Hospitalization 11/13/2007 61 Female 170 lb 7/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 6/29/2008 7/11/2008 Germany
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 2/2/1997 53 Male 7/9/2008 Pharmacist United States
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 5/12/2008 60 Female 200 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/22/2002 68 Female 100 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 Male 180 lb 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 5/11/2008 88 Female 7/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 5/11/2008 Female 8/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 12/12/2007 66 Male 143 lb 9/9/2008 Other Health Professional India
Primary
Concomitant
Drug Toxicity Hospitalization 66 Male 9/24/2008 Australia
Primary
Concomitant
Renal Failure Other Serious 2/22/2008 Male 176 lb 10/6/2008 Physician Spain
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 39 Female 10/7/2008 Other Health Professional Japan
Primary
Secondary
Renal Failure Other Serious 2/22/2008 Male 176 lb 10/15/2008 Physician Spain
Primary
Concomitant
Status Epilepticus Required Intervention 3/13/2007 70 Female 11/7/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/14/2009 28 Male 3/6/2009 Consumer Switzerland
Primary
Concomitant
Rectal Haemorrhage Required Intervention 11/24/2008 83 Female 212 lb 12/23/2008 United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/14/2009 Male 5/1/2009 Consumer Switzerland
Primary
Concomitant
Pneumonia Hospitalization 6/16/2009 50 Male 6/29/2009 Physician United States
Primary
Concomitant
Cerebellar Haemorrhage Hospitalization 7/5/2009 Female 7/29/2009 Pharmacist United States
Primary
Concomitant
Cerebellar Haemorrhage Hospitalization 7/5/2009 Female 7/30/2009 Pharmacist United States
Primary
Secondary
Concomitant
Sinus Arrhythmia Other Serious 46 Male 176 lb 7/30/2009
Primary
Secondary
Concomitant
Nausea Hospitalization 64 Female 8/11/2009 United States
Primary
Concomitant
Oedema Mouth 9/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Nausea Hospitalization 64 Female 8/20/2009 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 7/16/2009 Female 110 lb 9/1/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 7/16/2009 Female 110 lb 9/3/2009 Japan
Primary
Concomitant
Renal Failure Hospitalization 7/16/2009 Female 110 lb 9/15/2009 Japan
Primary
Concomitant
Tremor Hospitalization 10/24/2008 64 Male 170 lb 10/24/2008 Pharmacist United States
Primary
Secondary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Linear Iga Disease Other Serious 57 Female 10/6/2009 Other Health Professional Ireland
Primary
Concomitant
Status Asthmaticus Hospitalization 7/13/2009 Male 10/2/2009 Physician United States
Primary
Concomitant
Traumatic Lung Injury Hospitalization 70 Male 10/20/2009 United States
Primary
Concomitant
Status Asthmaticus Hospitalization 7/13/2009 Male 10/30/2009 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 70 Male 11/18/2009 United States
Primary
Concomitant
Traumatic Lung Injury Hospitalization 70 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Peritonitis Hospitalization 7/17/2009 58 Male 11/3/2009 United States
Primary
Concomitant
Pollakiuria 81 Male 12/9/2009 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 11/1/2009 83 Male 207 lb 11/2/2009 Pharmacist United States
Primary
Concomitant
Unevaluable Event Hospitalization 70 Male 1/7/2010 United States
Primary
Concomitant
Traumatic Lung Injury Hospitalization 70 Male 1/21/2010 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 12/17/2009 89 Male 185 lb 12/21/2009 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2008 75 Female 198 lb 3/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 70 Male 3/15/2010 United States
Primary
Concomitant
Visual Impairment Hospitalization 70 Male 3/26/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 73 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious 84 Male 6/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 49 Male 290 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 4/16/2010 73 Female 146 lb 7/13/2010 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/11/2010 82 Female 7/19/2010 India
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 72 Male 8/5/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 7/16/2009 69 Female 110 lb 8/27/2010 Physician Japan
Primary
Concomitant
Thyroxine Free Increased Other Serious 80 Female 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 9/10/2010 Physician Sweden
Primary
Concomitant
Interacting
Drug Ineffective Other Serious 80 Female 9/13/2010
Primary
Secondary
Nausea Other Serious Female 9/14/2010 Physician United States
Primary
Concomitant
Paranoia Other Serious 80 Female 9/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 59 Female 110 lb 9/29/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 10/13/2010 Physician Sweden
Primary
Concomitant
Interacting
Vertigo Other Serious 59 Female 110 lb 10/15/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Ulcer Other Serious Female 10/14/2010 Physician United States
Primary
Concomitant
Haematemesis Life Threatening 6/23/2010 8 Male 37 lb 11/15/2010 Physician Thailand
Primary
Secondary
Concomitant
Ulcer Other Serious Female 11/17/2010 Physician United States
Primary
Concomitant
Hypoglycaemia Life Threatening 8/11/2010 42 Female 150 lb 11/22/2010 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 6/23/2010 8 Male 35 lb 12/3/2010 Physician Thailand
Primary
Secondary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant
Ulcer Other Serious Female 12/22/2010 Physician United States
Primary
Concomitant
Death Death 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/11/2010 82 Female 12/13/2010 India
Primary
Secondary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/11/2010 82 Female 12/20/2010 India
Primary
Secondary
Concomitant
Urticaria Other Serious 12/8/2010 35 Female 128 lb 1/5/2011 Pharmacist Portugal
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/23/2010 8 Male 35 lb 1/20/2011 Physician Thailand
Primary
Secondary
Concomitant
Drug Interaction Death 1/25/2011 Consumer Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/1/2010 62 Female 1/29/2011 Physician United States
Primary
Concomitant
Hospitalisation Hospitalization Female 90 lb 2/28/2011 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/2/2004 65 Female 3/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Skin Papilloma Other Serious 2/19/2008 30 Female 3/17/2011 Physician France
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/23/2010 8 Male 35 lb 3/24/2011 Physician Thailand
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 6/23/2010 8 Male 35 lb 4/12/2011 Physician Thailand
Primary
Secondary
Concomitant
Anticonvulsant Drug Level Above Therapeutic Hospitalization 64 Female 4/25/2011 United States
Primary
Concomitant
Renal Failure Acute Hospitalization Female 217 lb 5/6/2011 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Death 3/3/2011 56 Female 104 lb 5/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/3/2011 56 Female 104 lb 5/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Disability 11/16/2001 2 Female 19 lb 5/4/2011 Japan
Primary
Secondary
Concomitant
Accidental Death Death 2/8/2011 40 Male 5/26/2011 Consumer United States
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 12/6/2010 50 Female 6/14/2011 Physician Japan
Primary
Secondary
C-reactive Protein Increased Death 6/30/2002 16 Female 73 lb 6/28/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Other Serious 3/1/2010 88 Female 160 lb 6/29/2011 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 59 Female 6/21/2011 Other Health Professional Sweden
Primary
Concomitant
Hypertension Life Threatening 4/22/2010 13 Male 90 lb 7/5/2011 Physician Japan
Primary
Concomitant
Pneumonia Death 10/18/2005 66 Male 8/8/2011 Physician Germany
Primary
Secondary
Concomitant
Blood Count Abnormal Hospitalization 1/1/2008 73 Female 8/9/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 10/15/2005 66 Male 8/17/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Effect Decreased 8/12/2011 61 Male 310 lb 8/18/2011 Consumer United States
Primary
Secondary
Concomitant
Headache Hospitalization 1/1/1995 59 Female 140 lb 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Murmur Hospitalization 65 Male 8/16/2011 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1995 59 Female 140 lb 9/2/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data