Furosemide combined with Itraconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 1/24/2006 Male 2/6/2006 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 1/24/2006 Male 2/15/2006 Physician Japan
Primary
Concomitant
Rash Hospitalization 1/12/2006 Female 117 lb 2/15/2006 Physician Portugal
Primary
Concomitant
Tremor Death 60 Male 5/24/2006 Physician United States
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 60 Male 6/12/2006 United States
Primary
Secondary
Concomitant
Tracheal Haemorrhage Hospitalization 5/31/2006 69 Male 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Blood Potassium Decreased 2/16/2005 75 Male 182 lb 9/8/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/30/2006 59 Male 9/26/2006 Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 62 Male 11/16/2006 Consumer Japan
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/14/2006 Physician Japan
Primary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 1/8/2007 Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 45 Female 2/1/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/4/2006 40 Male 154 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/27/2006 40 Male 154 lb 3/20/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/15/2006 61 Male 104 lb 3/28/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/15/2006 61 Male 104 lb 4/13/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/25/2007 10 Female 64 lb 4/23/2007 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 45 Female 4/27/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/5/2007 36 Male 174 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/22/2007 88 Female 9/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 10/25/2007 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Xanthopsia Other Serious 62 Male 1/28/2008 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 5/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 45 Male 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 5/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious Female 5/20/2008 Other Health Professional Germany
Primary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 6/26/2008 Physician Japan
Primary
Concomitant
Phaehyphomycosis Hospitalization 1/1/2001 79 Male 10/27/2008
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 59 Female 10/27/2008
Primary
Secondary
Concomitant
Phaehyphomycosis Hospitalization 1/1/2003 81 Female 10/27/2008
Primary
Secondary
Concomitant
Septic Shock Death 10/27/2008 78 Male 11/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/24/2008 Male 3/6/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/24/2008 Male 3/16/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2003 0 Male 13 lb 3/19/2009 France
Primary
Secondary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 6/2/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2009 43 Male 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 7/10/2009 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2008 Male 175 lb 8/11/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2008 Male 175 lb 9/4/2009 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 9/12/2009 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Female 155 lb 9/17/2009 United States
Primary
Concomitant
Pleural Effusion Life Threatening 9/3/2009 Female 10/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 9/24/2009 United States
Primary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 10/9/2009 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/12/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/26/2009 United States
Primary
Concomitant
Pancytopenia Other Serious 7/31/2009 74 Male 134 lb 11/2/2009 Physician Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 10/20/2009 Female 11/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 10/20/2009 Female 11/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 11/20/2009 United States
Primary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 1/29/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Tremor Other Serious 67 Male 3/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 67 Male 4/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 67 Male 4/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2009 Male 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 3/14/2010 65 Male 5/27/2010 Consumer United Kingdom
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 3/14/2010 65 Male 165 lb 6/11/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 3/14/2010 65 Male 6/25/2010 United Kingdom
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 3/14/2010 65 Male 165 lb 6/18/2010 United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/24/2010 72 Female 181 lb 7/23/2010 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/29/2009 65 Female 99 lb 9/30/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 5/26/2010 Male 18 lb 11/24/2010 Physician Japan
Primary
Concomitant
Platelet Destruction Increased Other Serious 7/27/2009 74 Male 134 lb 11/8/2010 Physician Japan
Primary
Concomitant
Hiccups Death 7/30/2010 49 Male 110 lb 12/17/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Death 3/25/2010 58 Male 150 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 3/25/2010 58 Male 150 lb 12/29/2010 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 10/22/2010 54 Male 176 lb 1/21/2011 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 4/29/2009 65 Female 99 lb 1/20/2011 Physician Japan
Primary
Concomitant
Hallucination Other Serious 10/11/2010 66 Male 2/4/2011 Other Health Professional Japan
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 7/8/2009 45 Male 1/26/2011 Consumer United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 67 Female 3/7/2011 Other Health Professional Japan
Primary
Concomitant
Hepatobiliary Disease Hospitalization 75 Female 3/23/2011 Physician Belgium
Primary
Concomitant
Abdominal Pain Other Serious 12/17/2009 73 Female 117 lb 4/5/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 9/17/2010 86 Male 4/15/2011 Other Health Professional France
Primary
Secondary
Concomitant
Agitation Other Serious 9/17/2010 86 Male 4/22/2011 Other Health Professional France
Primary
Secondary
Concomitant
Fungal Infection Other Serious 10/13/2009 36 Male 143 lb 4/27/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 9/17/2010 86 Male 4/28/2011 Other Health Professional France
Primary
Secondary
Concomitant
Interleukin-2 Receptor Increased Hospitalization 12/24/2010 76 Male 5/4/2011 Physician Japan
Primary
Concomitant
Pulmonary Infarction Other Serious 11/26/2010 62 Female 5/20/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Death 7/30/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Life Threatening 7/25/2010 60 Female 93 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/26/2010 24 Female 90 lb 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 5/30/2009 62 Female 104 lb 6/16/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Death 7/30/2010 49 Male 110 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Hypoaesthesia Death 9/21/2010 74 Female 6/28/2011 Physician Japan
Primary
Secondary
Concomitant
Aplastic Anaemia Death 10/4/2010 53 Female 121 lb 6/29/2011 Physician Japan
Primary
Concomitant
Clostridial Infection Other Serious 2/7/2011 59 Male 6/29/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 7/21/2010 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 2/18/2009 56 Female 128 lb 7/7/2011 Physician Japan
Primary
Secondary
Concomitant
Melaena Other Serious 10/18/2009 48 Female 97 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Multiple Myeloma Death 9/21/2010 74 Female 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Heart Transplant Rejection Other Serious 7/1/1998 20 Male 117 lb 7/25/2011 Physician Japan
Primary
Concomitant
Inflammation Other Serious 7/22/2010 85 Female 123 lb 7/29/2011 Physician Japan
Primary
Concomitant
Asthenia Death 4/27/2011 68 Male 152 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Fungaemia Death 6/22/2005 46 Male 126 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/16/2010 63 Female 8/22/2011 Physician Japan
Primary
Concomitant
Drug Interaction Hospitalization 7/27/2011 67 Male 168 lb 8/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Disability 5/25/2008 4 Male 37 lb 8/26/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Death 11/26/2010 62 Female 8/30/2011 Physician Japan
Primary
Concomitant
Myalgia Hospitalization 7/27/2011 67 Male 168 lb 8/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Disability 7/27/2011 67 Male 168 lb 9/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypocoagulable State Death 4/12/2010 60 Male 9/12/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/12/2010 60 Male 9/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Death 4/12/2010 60 Male 9/13/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 12/20/2010 76 Male 9/16/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Disability 6/6/2011 13 Female 88 lb 9/20/2011 Physician Japan
Primary
Concomitant
Hypocoagulable State Hospitalization 4/12/2010 60 Male 9/21/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Constipation Other Serious 4/12/2010 60 Male 9/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/12/2010 60 Male 9/23/2011 Physician Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/12/2010 60 Male 9/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Life Threatening 8/7/2010 Female 10/6/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cardiac Failure Death 6/24/2009 84 Female 86 lb 10/14/2011 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 4/12/2010 60 Male 10/14/2011 Physician Japan
Primary
Secondary
Concomitant
Hypotension Death 4/27/2011 68 Male 152 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 10/13/2009 36 Male 143 lb 11/7/2011 Physician Japan
Primary
Concomitant
Visual Impairment Death 6/6/2011 13 Female 88 lb 11/8/2011 Physician Japan
Primary
Concomitant
Pseudomonal Sepsis Life Threatening 11/21/2009 38 Male 165 lb 11/8/2011 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Death 12/20/2010 76 Male 11/22/2011 Physician Japan
Primary
Concomitant
Neutropenia Death 4/13/2010 60 Male 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 8/7/2010 Female 16 lb 11/29/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/12/2011 Consumer Netherlands
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 12/4/2011 79 Male 12/9/2011 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 2/7/2009 57 Male 139 lb 12/14/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/16/2011 Physician Netherlands
Primary
Secondary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 9/23/2011 66 Female 139 lb 12/21/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/23/2011 Consumer Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/29/2011 Physician Netherlands
Primary
Secondary
Concomitant
Diarrhoea Other Serious 4/11/2011 52 Female 126 lb 1/3/2012 Physician Japan
Primary
Concomitant
Anaemia Other Serious 12/20/2010 76 Male 1/4/2012 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 1/5/2012 Consumer Netherlands
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 11/26/2010 62 Female 1/31/2012 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 7/13/2010 6 Female 44 lb 2/6/2012 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Death 2/7/2009 57 Male 139 lb 2/7/2012 Physician Japan
Primary
Concomitant
Monocyte Count Increased Other Serious 7/22/2010 85 Female 123 lb 2/10/2012 Physician Japan
Primary
Concomitant
Bradycardia Hospitalization 11/3/2011 57 Male 2/13/2012 Pharmacist Spain
Primary
Concomitant
Interacting
Abdominal Pain Upper Death 4/2/2009 55 Male 165 lb 2/21/2012 Physician Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 1/1/2012 51 Female 3/1/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 3/2/2012 Physician Netherlands
Primary
Secondary
Concomitant
Insomnia Other Serious 4/4/2009 28 Female 115 lb 3/12/2012 Physician Japan
Primary
Secondary
Concomitant
Lung Disorder Life Threatening 1/21/2012 3/22/2012 Physician Japan
Primary
Concomitant
Viral Haemorrhagic Cystitis Hospitalization 6 Male 42 lb 4/3/2012 Physician Japan
Primary
Concomitant
Lung Disorder Life Threatening 1/21/2012 4/5/2012 Physician Japan
Primary
Concomitant
Skin Infection Other Serious 4/2/2011 27 Female 112 lb 4/9/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 7/23/2011 58 Male 4/10/2012 Other Health Professional Japan
Primary
Concomitant
Drug Interaction Other Serious 5/16/2012 Pharmacist Australia
Primary
Interacting

Drug Data