Frusemide combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oral Intake Reduced Other Serious 10/8/2003 Male 1/3/2006 United Kingdom
Primary
Secondary
Concomitant
Spleen Disorder Other Serious 2/25/2005 66 Male 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 6/16/2005 Female 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Hepatic Failure Death 9/1/2005 Male 1/27/2006 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 52 Male 2/15/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Life Threatening 7/1/2004 81 Male 224 lb 3/2/2006 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 1/26/2006 64 Male 3/3/2006
Primary
Secondary
Concomitant
Ascites Hospitalization 6/16/2005 Female 3/13/2006 United Kingdom
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/16/2005 Female 3/23/2006 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 2/5/2006 Female 3/29/2006 Pharmacist
Primary
Secondary
Concomitant
Viral Mutation Identified Hospitalization 6/16/2005 Female 3/29/2006 United Kingdom
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 5/1/2005 Male 3/29/2006 United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 52 Male 4/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 4/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Postoperative Infection Hospitalization 89 Female 7/7/2006 Physician United States
Primary
Secondary
Brugada Syndrome Other Serious 51 Female 12/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/26/2006 36 Female 117 lb 1/11/2007 Physician Ireland
Primary
Concomitant
Hyperkalaemia Hospitalization 78 Male 1/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 56 Male 1/26/2007 Other Health Professional India
Primary
Concomitant
Ventricular Tachycardia Life Threatening 12/8/2005 73 Male 1/30/2007 United Kingdom
Primary
Concomitant
Mobility Decreased Other Serious 6/4/2006 2/7/2007 Consumer United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/23/2007 41 Female 170 lb 2/14/2007 Physician Switzerland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/23/2007 40 Female 170 lb 3/1/2007 Physician Australia
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Death 12/30/2005 Male 3/22/2007 United Kingdom
Primary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 3/22/2007 United Kingdom
Primary
Secondary
Right Ventricular Failure Other Serious 1/24/2007 Male 4/3/2007 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 10/19/2004 41 Female 4/13/2007 Physician United Kingdom
Primary
Concomitant
Hepatitis B Other Serious 10/6/2004 57 Male 4/6/2007 Physician Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/1/2006 78 Male 4/17/2007 Consumer United Kingdom
Primary
Concomitant
Cardiac Failure Hospitalization 11/23/2006 92 Male 4/20/2007 Consumer Australia
Primary
Secondary
Concomitant
Palpitations Other Serious 8/1/2006 38 Female 5/10/2007 Physician United Kingdom
Primary
Concomitant
Fatigue Hospitalization 4/30/2007 Male 106 lb 5/16/2007 Hong Kong
Primary
Concomitant
Hyperglycaemia Other Serious Male 10 lb 5/21/2007
Primary
Secondary
Hyperglycaemia Other Serious Male 10 lb 5/22/2007 United Kingdom
Primary
Interacting
Weight Increased Other Serious 10/19/2004 41 Female 5/23/2007 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 11/1/2006 78 Male 218 lb 5/24/2007 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 2/27/2007 Male 106 lb 5/25/2007 Hong Kong
Primary
Concomitant
Post Herpetic Neuralgia Other Serious 4/12/2006 73 Female 170 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 10 Female 5/18/2007 United States
Primary
Concomitant
Syncope Other Serious 3/1/2007 78 Male 218 lb 6/11/2007 Consumer United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/1/2007 50 Female 220 lb 6/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 2/10/2001 86 Female 8/9/2007 Australia
Primary
Secondary
Staphylococcal Sepsis Hospitalization 72 Male 8/29/2007 Physician United Kingdom
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 9/7/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/6/2007 Male 9/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Fractured Sacrum Other Serious 70 Female 214 lb 9/26/2007 Physician Australia
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious Male 10 lb 9/28/2007
Primary
Secondary
Unevaluable Event Other Serious 1/1/2006 70 Female 214 lb 9/28/2007 Physician Australia
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 10/1/2007 United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 10 lb 10/3/2007 United Kingdom
Primary
Interacting
Hyperglycaemia Other Serious Male 10 lb 10/8/2007
Primary
Secondary
Hyperglycaemia Other Serious 10 lb 10/12/2007 United Kingdom
Primary
Interacting
Hyperglycaemia Other Serious 10 lb 10/12/2007 United Kingdom
Primary
Interacting
Vomiting Hospitalization 12/21/2005 10/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Asthenia Hospitalization 11/8/2007 58 Female 126 lb 11/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Asthenia Hospitalization 11/8/2007 58 Female 126 lb 11/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/26/2006 Female 117 lb 12/28/2007 Physician Ireland
Primary
Concomitant
Hyperglycaemia Other Serious Male 10 lb 2/25/2008 United Kingdom
Primary
Interacting
Syncope Life Threatening 2/4/2008 63 Male 165 lb 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/4/2007 43 Female 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 8/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/2/2007 Female 199 lb 8/29/2008 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Hospitalization 6/8/2007 Female 9/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Hospitalization 1/1/2007 81 Male 9/23/2008 Other Health Professional France
Primary
Concomitant
Lethargy Other Serious 5/16/2006 76 Female 10/22/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/26/2006 64 Male 10/22/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/1/2008 71 Male 10/28/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2006 78 Female 10/22/2008 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 2/5/2007 71 Female 11/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 2/5/2007 71 Female 11/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 12/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 12/19/2007 Male 12/18/2008 Pharmacist New Zealand
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 12/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/1/2008 71 Male 1/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Death 12/24/2008 1/16/2009 Physician India
Primary
Concomitant
Thrombocytopenia Death 12/19/2007 Male 1/19/2009 Pharmacist New Zealand
Primary
Concomitant
Thrombocytopenia Death 12/19/2007 Male 2/18/2009 Pharmacist New Zealand
Primary
Concomitant
Cardiac Failure Death 12/24/2008 2/23/2009 Physician India
Primary
Concomitant
Wheezing Life Threatening 10/1/2000 0 Female 99 lb 3/9/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Wheezing Life Threatening 10/1/2000 Female 99 lb 3/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Life Threatening 3/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Life Threatening 9/26/2000 0 Female 4/1/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Nocturnal Dyspnoea Other Serious 1/1/2008 Male 4/1/2009 Consumer United Kingdom
Primary
Secondary
Hypotension Other Serious 3/1/2009 Female 5/7/2009 Consumer Australia
Primary
Concomitant
Pulmonary Embolism Death 5/22/2008 91 5/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Nocturnal Dyspnoea Other Serious 1/1/2008 Male 5/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 5/22/2008 91 5/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 5/12/2009 69 Male 6/5/2009 Other Health Professional Germany
Primary
Concomitant
Left Ventricular Failure Death 5/12/2009 69 Male 6/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Other Serious 4/27/2009 54 Male 115 lb 6/16/2009 Physician United States
Primary
Secondary
Concomitant
Malaise Life Threatening 6/2/2008 83 Male 6/29/2009 Physician Australia
Primary
Secondary
Concomitant
Syncope Life Threatening 6/15/2009 Female 7/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 5/5/2009 Female 8/5/2009 Consumer Italy
Primary
Concomitant
Syncope Life Threatening 6/15/2009 Female 8/5/2009 Consumer Australia
Primary
Secondary
Concomitant
Nausea Hospitalization 6/29/2007 75 Female 8/7/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 Female 8/10/2009 Physician Germany
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 5/1/2009 Female 190 lb 8/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Mobility Decreased Other Serious 6/4/2006 83 Female 9/30/2009 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 9/18/2009 62 10/14/2009 Physician Malaysia
Primary
Concomitant
Wrist Fracture Hospitalization 9/2/2009 75 Female 130 lb 10/13/2009 Physician New Zealand
Primary
Concomitant
Renal Impairment Other Serious 9/18/2009 62 10/28/2009 Physician Malaysia
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/2/2009 Consumer United Kingdom
Primary
Concomitant
Wrist Fracture Hospitalization 9/2/2009 75 Female 130 lb 11/4/2009 Physician New Zealand
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myositis Life Threatening 6/1/2006 75 Male 11/10/2009 United Kingdom
Primary
Concomitant
Hypotension Other Serious 3/1/2009 62 Female 11/24/2009 Physician Australia
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2006 Female 117 lb 11/30/2009 Physician Ireland
Primary
Concomitant
Ventricular Tachycardia Other Serious 77 Female 12/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Bile Duct Cancer Life Threatening 70 Female 143 lb 12/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 Female 12/11/2009 Physician Germany
Primary
Concomitant
Renal Impairment Other Serious 9/18/2009 62 Female 110 lb 12/15/2009 Physician Malaysia
Primary
Concomitant
Vomiting Death 86 Female 2/2/2010 United States
Primary
Concomitant
Left Ventricular Failure Hospitalization 8/15/2009 Female 214 lb 2/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hyperglycaemia Other Serious Male 10 lb 3/5/2010 Other Health Professional United Kingdom
Primary
Interacting
Pulmonary Haemorrhage Hospitalization 7/29/2009 Male 185 lb 3/15/2010 Physician Poland
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 8/5/2009 Male 185 lb 3/31/2010 Physician Poland
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 9/2/2009 Female 130 lb 3/25/2010 Physician New Zealand
Primary
Concomitant
Renal Failure Acute Hospitalization 5/1/2009 69 Male 4/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 5/12/2009 69 Male 4/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 5/12/2009 69 Male 4/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Hospitalization 5/12/2009 69 Male 4/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Hospitalization 5/12/2009 69 Male 4/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Required Intervention 59 Male 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Body Temperature Decreased Other Serious 5/12/2009 69 Male 198 lb 4/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 61 Female 5/10/2010 Physician Germany
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 0 Male 4/30/2010 India
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 59 Male 5/13/2010 Consumer Australia
Primary
Concomitant
Bronchiectasis Hospitalization 11/20/2008 60 Male 6/21/2010 Other Health Professional Switzerland
Primary
Concomitant
Pressure Of Speech Other Serious Female 160 lb 6/22/2010 Physician Australia
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 2/27/2010 70 Female 176 lb 6/25/2010 Pharmacist United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 59 Male 231 lb 7/2/2010 Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Death 1/18/2002 60 Female 7/6/2010 Other Health Professional New Zealand
Primary
Concomitant
General Physical Health Deterioration Hospitalization 6/19/2010 78 Male 142 lb 7/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 4/14/2010 79 Female 7/9/2010 Consumer France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/18/2009 62 Female 110 lb 7/16/2010 Physician Malaysia
Primary
Concomitant
General Physical Health Deterioration Hospitalization 6/21/2010 78 Male 142 lb 7/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 4/5/2010 63 Female 105 lb 8/2/2010 Physician Malaysia
Primary
Concomitant
Malignant Ascites Hospitalization 8/9/2010 70 Male 8/23/2010 Physician Australia
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/20/2010 24 Female 128 lb 8/27/2010 Physician India
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/20/2010 24 Female 128 lb 9/2/2010 Physician India
Primary
Secondary
Concomitant
Malignant Ascites Hospitalization 8/9/2010 70 Male 9/10/2010 Physician Australia
Primary
Secondary
Concomitant
Malignant Ascites Hospitalization 8/9/2010 70 Male 9/13/2010 Physician Australia
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 8/23/2010 69 Male 9/7/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant

Drug Data