Fosamax combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Fatigue Other Serious 11/1/2005 75 Female 1/4/2006 Consumer United Kingdom
Primary
Concomitant
Dysphagia Hospitalization 64 Female 1/26/2006 Consumer United States
Primary
Concomitant
Spinal Compression Fracture Other Serious 1/1/2006 83 Female 2/7/2006 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 1/1/2005 70 Female 2/16/2006 Consumer New Zealand
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Initial Insomnia 10/28/2005 62 Female 1/5/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2000 53 Female 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Rib Fracture Hospitalization 1/1/2006 83 Female 3/16/2006 Consumer Australia
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 64 Female 209 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Venous Insufficiency Hospitalization 1/1/2004 43 Female 115 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/10/2005 75 Female 160 lb 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/4/2006 Male 4/5/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Diverticulitis Intestinal Haemorrhagic Hospitalization 1/1/2006 Female 4/12/2006 Consumer Australia
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 11/25/2003 43 Female 115 lb 5/1/2006 Physician United States
Primary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 7/5/2005 81 Female 141 lb 5/11/2006 Physician United Kingdom
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 5/18/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/4/2006 79 Male 6/1/2006 Pharmacist Ireland
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 1/1/2006 68 Male 6/8/2006 Consumer United States
Primary
Concomitant
Shoulder Pain Other Serious 3/1/2006 65 Female 101 lb 6/19/2006 Physician Japan
Primary
Concomitant
Rib Fracture Hospitalization 1/1/2006 83 Female 6/22/2006 Consumer Australia
Primary
Concomitant
Shoulder Pain Other Serious 3/1/2006 65 Female 101 lb 6/22/2006 Physician Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 1/1/2006 68 Male 6/26/2006 Other Health Professional United States
Primary
Concomitant
Breast Cancer Other Serious 5/1/2006 90 Female 7/10/2006 Consumer Australia
Primary
Concomitant
Thrombosis Hospitalization 1/1/2003 62 Female 7/13/2006 Consumer Australia
Primary
Concomitant
Metastatic Squamous Cell Carcinoma Hospitalization 1/1/2006 68 Male 187 lb 8/8/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/18/2006 Female 138 lb 9/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 2/27/2007 77 Male 3/16/2007 Consumer Australia
Primary
Concomitant
Irritability Other Serious 4/1/2006 71 Male 231 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 1/1/2005 83 Female 7/23/2007 Consumer United States
Primary
Concomitant
Hip Fracture Other Serious 72 Female 225 lb 10/3/2007 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/1996 52 Female 143 lb 12/13/2007 Physician United States
Primary
Concomitant
Gastric Haemorrhage Hospitalization 6/1/2007 85 Male 1/17/2008 Consumer Australia
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 1/1/1998 63 Female 196 lb 1/22/2008 Physician United States
Primary
Concomitant
Hip Fracture Other Serious 8/1/2007 67 Female 1/23/2008 Consumer Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2005 76 Male 2/19/2008 Consumer Australia
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 2/23/2008 70 Female 3/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Femur Fracture Other Serious 10/1/2004 63 Female 6/25/2008 Physician Australia
Primary
Concomitant
Myalgia Hospitalization 8/1/2007 74 Female 7/21/2008 Consumer United States
Primary
Concomitant
Myalgia Hospitalization 8/1/2007 74 Female 7/31/2008 Other Health Professional United States
Primary
Concomitant
Myalgia Hospitalization 8/1/2007 74 Female 8/15/2008 Other Health Professional United States
Primary
Concomitant
Myalgia Hospitalization 8/1/2007 74 Female 247 lb 9/15/2008 Physician United States
Primary
Concomitant
Myalgia Hospitalization 8/1/2007 74 Female 247 lb 9/18/2008 Physician United States
Primary
Concomitant
Myalgia Hospitalization 8/1/2007 74 Female 247 lb 9/29/2008 Physician United States
Primary
Concomitant
Impaired Healing Other Serious 6/13/2008 80 Female 10/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Disability 69 Female 145 lb 11/26/2008 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 80 Female 123 lb 12/31/2008 Consumer United States
Primary
Concomitant
Off Label Use Hospitalization 12/26/2006 72 Female 1/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Rheumatoid Arthritis Hospitalization 4/4/2007 Female 126 lb 2/5/2009 United Kingdom
Primary
Concomitant
Off Label Use Hospitalization 12/26/2006 72 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Neuropathy Peripheral Other Serious 1/1/2008 Female 110 lb 2/20/2009 Physician United States
Primary
Concomitant
Drug Eruption Hospitalization 3/1/2009 36 Female 3/10/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/3/2009 75 Male 4/3/2009 Physician Japan
Primary
Secondary
Concomitant
Erythema Hospitalization 2/28/2009 36 Female 108 lb 4/7/2009 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 150 lb 4/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2007 5/1/2009 Physician United States
Primary
Concomitant
Nasopharyngitis 12/1/2008 Female 5/4/2009 Physician United States
Primary
Concomitant
Vocal Cord Paralysis Hospitalization 7/25/2008 Female 108 lb 7/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/3/2009 75 Male 7/8/2009 Physician Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 1/1/1998 72 Female 196 lb 7/22/2009 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 8/1/2008 83 Female 121 lb 8/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 8/9/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/11/2008 Female 8/21/2009 Consumer United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 4/1/2009 Female 236 lb 9/16/2009 Consumer United States
Primary
Secondary
Concomitant
Interacting
Ovarian Cancer Other Serious 6/1/2003 Female 130 lb 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 6/5/2009 67 Female 93 lb 6/8/2009 Pharmacist United States
Primary
Concomitant
Cardiac Valve Disease Hospitalization 1/1/2008 76 Female 10/15/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 12/10/2009 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/18/2008 79 Male 150 lb 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retinal Detachment Other Serious 11/6/2009 Male 1/24/2010 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 1/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 73 Female 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Retinal Detachment Other Serious 11/6/2009 39 Male 4/12/2010 Other Health Professional Canada
Primary
Concomitant
Retinal Tear Hospitalization 1/22/2010 39 Male 4/12/2010 Consumer Canada
Primary
Concomitant
Thrombocytopenia Death 74 Male 4/13/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 3/16/2001 63 Male 129 lb 5/6/2010 United States
Primary
Concomitant
Vomiting Other Serious 3/16/2001 63 Male 129 lb 5/17/2010 United States
Primary
Concomitant
Vomiting Other Serious 3/16/2001 63 Male 129 lb 6/9/2010 United States
Primary
Concomitant
Death Death 5/16/2010 52 Female 168 lb 6/15/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 5/13/2010 Male 112 lb 6/16/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 6/7/2010 United States
Primary
Concomitant
Vomiting Other Serious 3/1/2008 82 Male 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/16/2001 63 Male 129 lb 6/18/2010 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 5/23/2010 85 Female 130 lb 6/16/2010 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 5/13/2010 81 Male 112 lb 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus 11/1/2006 75 Female 184 lb 6/28/2010 Consumer United States
Primary
Concomitant
Constipation 1/25/2009 75 Female 190 lb 6/29/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/11/2009 71 Female 184 lb 6/29/2010 Consumer United States
Primary
Concomitant
Nausea 1/19/2007 76 Female 200 lb 7/9/2010 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 11/9/2008 84 Female 103 lb 7/29/2010 Physician United States
Primary
Concomitant
Interacting
Syncope Other Serious 7/1/2008 84 Female 8/12/2010 Lawyer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 8/10/2008 68 Female 8/27/2010 Physician Australia
Primary
Secondary
Concomitant
Rash Erythematous 10/1/2009 85 Female 9/17/2010 Physician Japan
Primary
Secondary
Deep Vein Thrombosis Death 9/5/2010 49 Female 9/17/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 3/1/2008 82 Male 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization Female 9/23/2010 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 4/13/2010 83 Female 9/27/2010 Other Health Professional United States
Primary
Concomitant
Retinal Tear Other Serious 1/22/2010 39 Male 9/28/2010 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 3/16/2001 63 Male 129 lb 10/5/2010 Physician United States
Primary
Concomitant
Shock Death Female 10/21/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/16/2008 82 Female 174 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Disability 4/1/2010 77 Female 220 lb 11/30/2010 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/1/2010 56 Female 12/1/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 82 Female 11/17/2010 United States
Primary
Concomitant
Ageusia 11/21/2010 87 Female 132 lb 12/7/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2007 63 Male 192 lb 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/1/2010 52 Female 1/10/2011 Other Health Professional Canada
Primary
Concomitant
Osteomyelitis Disability 1/1/2004 68 Female 1/10/2011 Physician Japan
Primary
Concomitant
Insomnia Disability 4/1/2010 77 Female 220 lb 1/13/2011 Consumer United States
Primary
Secondary
Concomitant
Osteomyelitis Disability 1/1/2004 68 Female 1/14/2011 Physician Japan
Primary
Concomitant
Ageusia 11/21/2010 87 Female 132 lb 1/4/2011 United States
Primary
Concomitant
Anaemia Hospitalization 11/8/2010 76 Male 119 lb 1/20/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective 10/1/2010 76 Female 1/30/2011 Consumer United States
Primary
Concomitant
Osteomyelitis Disability 7/1/2009 68 Female 2/4/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 1/1/2010 76 Male 119 lb 2/4/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Cholesterol Increased Hospitalization 8/1/2010 52 Female 2/11/2011 Other Health Professional Canada
Primary
Concomitant
Jaw Fracture Death 9/5/2005 71 Male 2/11/2011 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Disability 9/5/2005 71 Male 2/16/2011 Physician United States
Primary
Concomitant
Osteomyelitis Disability 7/1/2009 68 Female 2/17/2011 Physician Japan
Primary
Concomitant
Jaw Fracture Other Serious 8/22/2007 71 Male 2/21/2011 Physician United States
Primary
Concomitant
Product Taste Abnormal 2/16/2011 83 Female 2/21/2011 Pharmacist United States
Primary
Concomitant
Oesophageal Rupture Hospitalization 84 Female 2/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Rupture Life Threatening 84 Female 2/23/2011 Physician United Kingdom
Primary
Concomitant
Blood Cholesterol Increased Hospitalization 8/1/2010 52 Female 244 lb 3/7/2011 Consumer Canada
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 8/22/2007 71 Male 3/11/2011 Physician United States
Primary
Concomitant
Nephrolithiasis Other Serious 8/22/2007 71 Male 3/23/2011 Physician United States
Primary
Concomitant
Bladder Dysfunction Other Serious 10/1/2004 49 Female 147 lb 3/24/2011 United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Disability 8/22/2007 71 Male 3/31/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 76 Female 4/1/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 8/1/2010 52 Female 244 lb 4/5/2011 Consumer Canada
Primary
Concomitant
Throat Irritation 2/16/2011 83 Female 4/7/2011 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 8/1/2010 52 Female 244 lb 4/11/2011 Consumer Canada
Primary
Concomitant
Intervertebral Disc Protrusion Death 10/1/2004 49 Female 147 lb 4/14/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 2/19/2011 66 Female 147 lb 4/13/2011 Physician United States
Primary
Concomitant
Head Injury Hospitalization 8/22/2007 71 Male 4/15/2011 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 8/10/2008 68 Female 180 lb 4/26/2011 Physician Australia
Primary
Secondary
Concomitant
Jaundice Other Serious 8/3/2007 83 Male 203 lb 4/27/2011 United States
Primary
Concomitant
Rash Death 10/15/2008 73 Female 108 lb 5/3/2011 Physician United States
Primary
Concomitant
Pain Hospitalization 8/1/2004 74 Female 114 lb 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 8/1/2004 74 Female 114 lb 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/8/2005 68 Female 148 lb 5/9/2011 Physician United States
Primary
Concomitant
Renal Injury Hospitalization 8/1/2004 74 Female 114 lb 5/10/2011 Consumer Germany
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 1/8/2006 71 Male 5/19/2011 Physician United States
Primary
Concomitant
Lung Disorder Other Serious 86 Female 5/31/2011 Physician Norway
Primary
Concomitant
Bone Pain Other Serious 76 Female 7/26/2011 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 67 Female 7/26/2011 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Female 237 lb 8/9/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 4/28/2010 Female 154 lb 8/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data