Fosamax combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyponatraemia Hospitalization 10/1/2005 80 Female 148 lb 1/9/2006 Other Health Professional France
Primary
Secondary
Concomitant
Viral Infection Hospitalization 12/19/2005 Female 2/7/2006 Consumer United States
Primary
Concomitant
Fall Other Serious 1/12/2006 85 Female 2/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 12/4/2003 63 Female 154 lb 4/10/2006 Lawyer United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 5/18/2006 Physician United States
Primary
Concomitant
Medication Error Hospitalization 8/1/2000 68 Female 5/24/2006 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral 5/1/2006 75 Female 6/6/2006 United States
Primary
Concomitant
Renal Disorder 1/1/2004 80 Male 7/21/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/3/2006 90 Female 7/26/2006 Physician France
Primary
Secondary
Concomitant
Periodontitis Hospitalization 71 Female 8/2/2006 Other Health Professional Sweden
Primary
Concomitant
Tooth Infection Other Serious 6/1/2006 59 Female 8/4/2006 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Hospitalization 4/1/2006 74 Female 159 lb 8/8/2006 Consumer Mexico
Primary
Concomitant
Osteonecrosis Hospitalization 71 Female 8/9/2006 Other Health Professional Sweden
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 84 Female 9/8/2006 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Hospitalization 4/1/2006 74 Female 159 lb 9/12/2006 Consumer Mexico
Primary
Concomitant
Vomiting Other Serious 2/1/2005 Female 130 lb 9/28/2006 Consumer United States
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 8/18/2006 50 Female 145 lb 10/6/2006 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 84 Female 10/27/2006 Physician United States
Primary
Concomitant
Death Death 10/15/2006 88 Female 10/23/2006 Physician United States
Primary
Concomitant
Vomiting Projectile Other Serious 10/20/2006 81 Female 172 lb 11/9/2006 Pharmacist United States
Primary
Concomitant
Oedema Peripheral 5/1/2006 75 Female 213 lb 9/12/2006 Consumer United States
Primary
Concomitant
Breast Cancer In Situ Hospitalization 12/7/2005 Female 12/13/2006 Physician United States
Primary
Concomitant
Superinfection Other Serious 1/1/2006 79 Female 154 lb 12/21/2006 Physician Germany
Primary
Concomitant
Weight Decreased Hospitalization 10/15/2006 88 Female 123 lb 12/22/2006 Physician United States
Primary
Concomitant
Gastric Ulcer Perforation Life Threatening 12/12/2006 86 Male 1/8/2007 Other Health Professional Norway
Primary
Concomitant
Oral Discomfort 12/1/2005 68 Female 147 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2005 68 Female 11/28/2006 United States
Primary
Concomitant
Skin Lesion Other Serious 1/1/2005 68 Female 298 lb 11/28/2006 Physician United States
Primary
Concomitant
Visual Acuity Reduced Disability 9/3/2006 Female 1/25/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/1/2006 Female 97 lb 4/11/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 10/15/2006 88 Female 123 lb 2/16/2007 Physician United States
Primary
Concomitant
Troponin Increased Hospitalization 9/25/2002 66 Female 2/27/2007 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 2/9/2007 57 Female 2/26/2007 Consumer United States
Primary
Secondary
Concomitant
Progressive Multiple Sclerosis Hospitalization 12/10/2006 52 Female 2/28/2007 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 78 Female 149 lb 4/16/2004 Physician United States
Primary
Concomitant
Tooth Disorder Other Serious 7/2/1999 99 Female 3/23/2007 Physician United States
Primary
Concomitant
Hypoaesthesia 11/9/2006 66 Female 3/27/2007 Physician United States
Primary
Concomitant
Sensation Of Foreign Body 11/1/2005 47 Female 165 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 7/1/2005 61 Female 198 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 3/7/2007 59 Female 4/17/2007 Physician United States
Primary
Concomitant
Off Label Use Other Serious 1/1/2007 59 Female 172 lb 5/25/2007 Physician United States
Primary
Concomitant
Urticaria Other Serious 7/2/1996 89 Female 148 lb 7/5/2007 Physician United States
Primary
Concomitant
Urticaria Other Serious 7/2/1996 89 Female 148 lb 7/13/2007 Physician United States
Primary
Concomitant
Dizziness 4/12/2007 Female 8/21/2007 Other Health Professional United States
Primary
Concomitant
Dizziness 12/11/2006 77 Female 114 lb 8/16/2007 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 1/1/2004 72 Female 134 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 10/9/2007 Physician Australia
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 8/1/2005 76 Female 10/23/2007 Other Health Professional United States
Primary
Concomitant
Skin Cancer Other Serious 10/1/2007 81 Male 10/29/2007 Consumer France
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2006 59 Female 121 lb 10/30/2007 Other Health Professional United States
Primary
Concomitant
Skin Cancer Other Serious 10/1/2007 81 Male 10/31/2007 Physician France
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 9/25/2007 Female 11/1/2007 Other Health Professional United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 12/1/2003 72 Female 134 lb 11/2/2007 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/25/2005 76 Female 11/8/2007 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 59 Female 121 lb 11/12/2007 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/25/2005 76 Female 11/12/2007 Other Health Professional United States
Primary
Concomitant
Dyspnoea 10/1/2006 87 Female 11/13/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/25/2005 76 Female 11/29/2007 Other Health Professional United States
Primary
Concomitant
Thinking Abnormal Other Serious 11/1/2007 Female 131 lb 12/7/2007 Consumer United States
Primary
Concomitant
Somnolence Other Serious 6/1/2007 Female 126 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 11/30/2007 76 Female 154 lb 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/11/2002 68 Female 11/28/2007 United States
Primary
Concomitant
Subdural Haematoma Life Threatening 12/8/2007 73 Female 12/26/2007 Pharmacist United States
Primary
Concomitant
Urticaria Other Serious 7/2/1996 89 Female 148 lb 1/18/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 9/1/2007 62 Female 147 lb 1/18/2008 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 1/25/2008 Belgium
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 2/6/2008 Belgium
Primary
Concomitant
Renal Failure Life Threatening 1/16/2008 84 Female 2/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Prothrombin Time Abnormal Other Serious 9/25/2007 Female 2/18/2008 Other Health Professional United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 4/8/2008 Physician Belgium
Primary
Concomitant
Urticaria Other Serious 7/2/1996 89 Female 148 lb 5/15/2008 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 5/29/2008 Belgium
Primary
Concomitant
Dyspnoea 81 Female 98 lb 6/25/2008
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 6/24/2008 Belgium
Primary
Concomitant
Migraine 1/1/1998 52 Female 150 lb 7/23/2008 Consumer United States
Primary
Concomitant
Hepatitis Acute Hospitalization 7/17/2008 78 Female 139 lb 8/15/2008 Consumer Belgium
Primary
Concomitant
Thyroid Neoplasm Other Serious 7/19/2001 72 Female 134 lb 10/2/2008 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Disability 10/17/2007 84 Female 112 lb 11/26/2008 Physician United States
Primary
Concomitant
Temperature Intolerance 60 Female 170 lb 12/17/2008 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 12/17/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 12/5/2008 69 Female 168 lb 1/5/2009 Consumer United States
Primary
Concomitant
Tooth Abscess Required Intervention 4/1/2008 Female 7/8/2008 Other Health Professional United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 7/19/2001 72 Female 134 lb 1/23/2009 Other Health Professional United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 7/19/2001 72 Female 134 lb 1/27/2009 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 12/5/2008 69 Female 168 lb 3/16/2009 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 73 Female 3/16/2009 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 3/23/2009 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Disorder 4/1/2008 Female 287 lb 4/13/2009 Physician United States
Primary
Concomitant
Urticaria Other Serious 2/25/2008 88 Male 140 lb 4/21/2009 United States
Primary
Secondary
Concomitant
Temporomandibular Joint Syndrome Other Serious 1/1/2005 66 Female 5/11/2009 Other Health Professional United States
Primary
Concomitant
Application Site Burn Other Serious 5/3/2009 59 Female 197 lb 5/13/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 65 Female 143 lb 5/19/2009 Other Health Professional United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 7/19/2001 72 Female 134 lb 5/19/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 1/1/2002 73 Female 6/2/2009 Other Health Professional United States
Primary
Concomitant
Breast Cancer Other Serious 4/30/2004 53 Female 139 lb 5/19/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Disability 85 Female 6/8/2009 Physician United States
Primary
Concomitant
Blood Glucose Increased 5/18/2009 Female 6/8/2009 Consumer
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2002 65 Female 143 lb 6/9/2009 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Death Death Female 250 lb 6/15/2009 Consumer United States
Primary
Concomitant
Reflux Oesophagitis Hospitalization 2/1/2009 93 Female 6/18/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Injury Other Serious 3/21/2009 Female 168 lb 6/18/2009 United States
Primary
Concomitant
Cardiac Failure Death Female 250 lb 6/26/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/21/2009 Female 168 lb 6/29/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2002 62 Female 143 lb 7/6/2009 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious 6/3/2009 75 Female 7/9/2009 Physician Spain
Primary
Concomitant
Unevaluable Event Death 65 Female 155 lb 7/10/2009 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 1/1/2002 73 Female 104 lb 9/2/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 65 Female 155 lb 8/24/2009 United States
Primary
Concomitant
Cough Other Serious 6/1/2009 80 Female 8/7/2009 United States
Primary
Concomitant
Pancreatitis Other Serious Female 108 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/4/2002 49 Male 147 lb 9/23/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Female 155 lb 9/17/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 9/24/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2000 91 Female 10/7/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 91 Female 10/13/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/12/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/26/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 91 Female 11/13/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2009 60 Female 11/20/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 11/20/2009 United States
Primary
Concomitant
Vertigo Hospitalization 66 Female 11/20/2009 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 91 Female 12/1/2009 Physician United States
Primary
Concomitant
Death Death Female 111 lb 12/3/2009 Consumer United States
Primary
Concomitant
Malaise Death 11/17/2009 Female 111 lb 12/22/2009 Other Health Professional United States
Primary
Concomitant
Lung Infiltration Other Serious 3/24/2009 Female 1/19/2010 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 2/1/2009 Male 220 lb 1/20/2010 Physician Germany
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 1/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 1/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 1/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2009 60 Female 1/28/2010 Physician United States
Primary
Concomitant
Nausea 9/15/2008 62 Female 134 lb 2/25/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 66 Female 2/17/2010 Lawyer United States
Primary
Concomitant
Lung Infiltration Other Serious 3/24/2009 Female 3/3/2010 Physician Germany
Primary
Concomitant
Product Substitution Issue Required Intervention 10/5/2005 Female 169 lb 3/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thirst Other Serious 12/1/2007 Female 3/17/2010 Lawyer United States
Primary
Concomitant
Tremor Hospitalization 1/15/2010 91 124 lb 1/19/2010 Pharmacist United States
Primary
Concomitant
Vertigo Hospitalization 66 Female 3/25/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 192 lb 4/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 4/14/2010 79 Female 145 lb 5/7/2010 Consumer United Kingdom
Primary
Concomitant
Mixed Hepatocellular Cholangiocarcinoma Life Threatening Male 5/10/2010 Other Health Professional Germany
Primary
Concomitant
Urine Output Decreased Other Serious 10/1/2007 63 Male 193 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/18/2010 71 Female 6/1/2010 Consumer United States
Primary
Concomitant
Thirst Other Serious 12/1/2007 84 Female 6/15/2010 Lawyer United States
Primary
Concomitant
Breast Cancer Other Serious 1/1/2001 64 Female 134 lb 4/5/2010 United States
Primary
Secondary
Concomitant

Drug Data