Folinic Acid combined with Panitumumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Embolism Hospitalization 2/8/2006 Male 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Death 5/21/2006 Female 11/2/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 10/15/2006 Female 11/2/2006 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 10/27/2006 Female 11/10/2006 Physician Australia
Primary
Secondary
Concomitant
Ectropion Other Serious 10/10/2006 Female 11/10/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/20/2006 Male 12/20/2006 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization 11/13/2006 Male 12/20/2006 Physician Australia
Primary
Concomitant
Vena Cava Thrombosis Hospitalization 11/26/2006 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2006 Female 12/27/2006 Physician United States
Primary
Concomitant
Dyspnoea Death 10/15/2006 Female 1/9/2007 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 12/26/2006 Female 1/11/2007 Physician Australia
Primary
Secondary
Vena Cava Thrombosis Other Serious 11/29/2006 Male 1/11/2007 Physician Australia
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 1/11/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Death 10/15/2006 Female 1/17/2007 Other Health Professional United States
Primary
Secondary
Hypomagnesaemia Hospitalization 3/14/2006 Male 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Peritoneal Infection Hospitalization 11/26/2006 Female 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/27/2006 Female 147 lb 1/26/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 10/2/2006 Female 2/2/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 5/26/2006 Female 167 lb 2/2/2007 Physician United States
Primary
Concomitant
Rash Hospitalization 10/27/2006 Female 2/5/2007 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/25/2006 Male 2/22/2007 Physician Australia
Primary
Secondary
Urinary Retention Hospitalization 6/7/2005 Male 2/26/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 2/26/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/26/2006 Female 3/1/2007 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 3/14/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 3/16/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 9/25/2006 Male 3/20/2007 Physician Australia
Primary
Secondary
Pulmonary Embolism Other Serious 3/13/2007 Male 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 4/12/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/11/2006 Male 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/5/2006 Male 4/30/2007 Physician Australia
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 3/14/2006 Male 5/14/2007 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Death 10/15/2006 Female 5/14/2007 United States
Primary
Secondary
Hypotension Hospitalization 11/5/2006 Male 5/18/2007 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/11/2007 Female 5/24/2007 Physician Australia
Primary
Secondary
Vomiting Life Threatening 6/8/2006 Female 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/5/2006 Male 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Dyspnoea Death 10/15/2006 Female 166 lb 6/12/2007 Consumer United States
Primary
Secondary
Dyspnoea Death 10/15/2006 Female 166 lb 6/12/2007 Consumer United States
Primary
Secondary
Pulmonary Embolism Hospitalization 5/11/2007 Female 6/13/2007 Physician Australia
Primary
Secondary
Pulmonary Embolism Hospitalization 5/11/2007 Female 6/18/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 7/27/2006 Female 147 lb 6/28/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 6/22/2007 Female 7/5/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/24/2007 Male 7/9/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/23/2007 Male 7/18/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/23/2007 Female 7/30/2007 Physician France
Primary
Secondary
Vomiting Hospitalization 12/26/2006 Female 8/6/2007 Physician Australia
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 7/9/2007 Female 8/15/2007 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/16/2007 Male 8/27/2007 Physician Australia
Primary
Concomitant
Pyrexia Hospitalization 8/16/2007 Male 8/31/2007 Physician Australia
Primary
Concomitant
Gastric Haemorrhage Hospitalization 8/3/2007 Female 9/10/2007 Physician Chile
Primary
Concomitant
Cellulitis Hospitalization 8/13/2007 Male 9/11/2007 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/9/2007 Female 9/14/2007 Physician Canada
Primary
Concomitant
Pyrexia Hospitalization 8/16/2007 Male 9/20/2007 Physician Australia
Primary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 9/24/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/19/2007 Male 10/1/2007 Physician United States
Primary
Concomitant
Pain Hospitalization 9/9/2007 Male 10/3/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/2/2006 Female 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/19/2007 Male 10/9/2007 Physician United States
Primary
Concomitant
Hyponatraemia Hospitalization 7/9/2007 Female 10/11/2007 Physician Canada
Primary
Concomitant
Hypokalaemia Hospitalization 10/8/2007 Female 10/29/2007 Physician United States
Primary
Secondary
Pulmonary Embolism Other Serious 9/19/2007 Male 11/12/2007 Physician United States
Primary
Concomitant
Gastric Haemorrhage Hospitalization 8/3/2007 Female 11/14/2007 Physician Chile
Primary
Concomitant
Pulmonary Embolism Other Serious 9/19/2007 Male 11/29/2007 Physician United States
Primary
Concomitant
Pain Hospitalization 9/9/2007 Male 12/17/2007 Physician United States
Primary
Secondary
Concomitant
Gastric Haemorrhage Hospitalization 8/3/2007 Female 93 lb 12/18/2007 Physician Chile
Primary
Concomitant
Small Intestinal Obstruction Life Threatening 12/16/2006 Female 12/21/2007 Physician United States
Primary
Concomitant
Oesophageal Pain Hospitalization 9/9/2007 Male 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/16/2006 Female 1/8/2008 Physician United States
Primary
Concomitant
Haemoptysis Hospitalization 1/7/2008 Male 2/27/2008 Physician Poland
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2006 Female 3/7/2008 United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 1/7/2008 Male 3/10/2008 Physician Poland
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 8/1/2006 Male 3/15/2008 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 2/26/2008 Female 3/17/2008 Physician Australia
Primary
Concomitant
Large Intestine Perforation Hospitalization 3/23/2006 Male 3/19/2008 Physician United States
Primary
Secondary
Mucosal Inflammation Hospitalization 9/19/2006 Female 3/20/2008 Physician United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 1/7/2008 Male 3/21/2008 Physician Poland
Primary
Secondary
Concomitant
Pain Other Serious 2/26/2008 Female 3/31/2008 Physician Australia
Primary
Secondary
Fungal Infection Hospitalization 7/27/2007 Male 176 lb 4/14/2008 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/8/2007 Female 5/1/2008 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 4/20/2008 Male 5/2/2008 Other Health Professional Australia
Primary
Secondary
Pyrexia Hospitalization 4/21/2008 Male 5/2/2008 Physician Australia
Primary
Secondary
Febrile Neutropenia Hospitalization 4/20/2008 Male 5/7/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization Male 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 8/1/2006 Male 140 lb 6/10/2008 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 2/12/2008 Female 8/19/2008 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 5/15/2008 Male 243 lb 8/29/2008 Physician Germany
Primary
Concomitant
Ischaemic Stroke Hospitalization 4/22/2006 Male 10/23/2008 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 4/22/2006 Male 11/3/2008 Physician United States
Primary
Secondary
Concomitant
Generalised Oedema Hospitalization 10/25/2007 Male 12/9/2008 Physician Italy
Primary
Secondary
Deep Vein Thrombosis Other Serious 5/15/2008 Male 243 lb 12/11/2008 Physician Germany
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/25/2007 Male 12/22/2008 Physician Italy
Primary
Concomitant
Fungal Infection Hospitalization 7/27/2007 Male 176 lb 12/30/2008 Physician Italy
Primary
Concomitant
Pneumonitis Hospitalization 10/27/2007 Male 2/24/2009 Physician Italy
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 2/9/2009 Male 2/26/2009 Physician Canada
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 5/15/2008 Male 243 lb 3/23/2009 Physician Germany
Primary
Concomitant
Hypomagnesaemia Other Serious 4/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Xerosis Other Serious 11/16/2008 Male 183 lb 5/26/2009 Physician Italy
Primary
Concomitant
Xerosis Other Serious 11/12/2008 Male 211 lb 5/26/2009 Physician Italy
Primary
Concomitant
Neutropenia Hospitalization 5/21/2009 82 Male 6/8/2009 Physician United Kingdom
Primary
Secondary
Rectal Cancer Metastatic Hospitalization 10/26/2006 Female 6/9/2009 Physician United Kingdom
Primary
Concomitant
Hypomagnesaemia Hospitalization 4/1/2008 Male 6/15/2009 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 5/21/2009 82 Male 6/15/2009 Physician United Kingdom
Primary
Secondary
Xerosis Other Serious 11/16/2008 Male 183 lb 6/26/2009 Physician Italy
Primary
Concomitant
Xerosis Other Serious 11/12/2008 Male 211 lb 6/26/2009 Physician Italy
Primary
Concomitant
Vomiting Hospitalization 6/23/2007 Female 6/30/2009 Physician France
Primary
Secondary
Pneumonitis Hospitalization 10/27/2007 Male 7/31/2009 Physician Italy
Primary
Concomitant
Xerosis Other Serious 11/16/2008 Male 183 lb 8/7/2009 Physician Italy
Primary
Concomitant
Xerosis Other Serious 11/12/2008 Male 211 lb 8/7/2009 Physician Italy
Primary
Concomitant
Pneumonitis Hospitalization 10/27/2007 Male 8/7/2009 Physician Italy
Primary
Concomitant
Neutropenia Hospitalization 5/21/2009 82 Male 8/14/2009 Physician United Kingdom
Primary
Concomitant
Ischaemic Stroke Hospitalization 4/22/2006 Male 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 10/27/2007 Male 9/3/2009 Physician Italy
Primary
Concomitant
Xerosis Other Serious 11/16/2008 Male 183 lb 9/28/2009 Physician Italy
Primary
Concomitant
Xerosis Other Serious 11/12/2008 Male 211 lb 9/28/2009 Physician Italy
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 46 Female 11/20/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Failure Death 10/28/2008 68 Male 11/25/2009 Other Health Professional Sweden
Primary
Secondary
Hepatic Failure Death 10/28/2008 68 Male 12/3/2009 Other Health Professional Sweden
Primary
Secondary
Vomiting Hospitalization 4/16/2008 Male 12/4/2009 Physician Spain
Primary
Secondary
Neutropenia Hospitalization 5/21/2009 82 Male 12/10/2009 Physician United Kingdom
Primary
Concomitant
Hepatic Failure Hospitalization 10/28/2008 Male 12/22/2009 Physician Sweden
Primary
Secondary
Neutropenia Hospitalization 5/21/2009 82 Male 12/29/2009 Physician United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 46 Female 1/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/8/2009 Female 138 lb 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Hospitalization 4/17/2008 Male 2/3/2010 Physician Spain
Primary
Secondary
Gastrointestinal Toxicity Hospitalization 4/17/2008 Male 2/16/2010 Physician Spain
Primary
Secondary
Neutropenia Hospitalization 5/21/2009 82 Male 2/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 60 Female 3/2/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Hospitalization 4/17/2008 Male 3/10/2010 Physician Spain
Primary
Secondary
Respiratory Failure Hospitalization 3/19/2010 Male 159 lb 3/31/2010 Physician Spain
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/19/2010 72 Male 159 lb 4/8/2010 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/26/2006 47 Female 4/27/2010 Physician United Kingdom
Primary
Concomitant
Cardiac Arrest Life Threatening 6/26/2010 68 Female 7/15/2010 Physician United Kingdom
Primary
Concomitant
Dehydration Life Threatening 6/26/2010 68 Female 7/20/2010 Physician United Kingdom
Primary
Concomitant
Device Related Infection Hospitalization 7/12/2010 73 Female 7/21/2010 Physician Spain
Primary
Concomitant
Cardiac Arrest Life Threatening 6/26/2010 68 Female 8/19/2010 Physician United Kingdom
Primary
Concomitant
Lymphopenia Other Serious 4/22/2010 68 Female 222 lb 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Device Related Infection Hospitalization 7/12/2010 73 Female 8/23/2010 Physician Spain
Primary
Secondary
Device Related Infection Hospitalization 7/12/2010 73 Female 9/17/2010 Physician Spain
Primary
Secondary
Lymphopenia Other Serious 4/22/2010 68 Female 222 lb 9/20/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/24/2010 61 Male 9/29/2010 Physician Belgium
Primary
Concomitant
General Physical Health Deterioration Hospitalization 9/25/2010 10/21/2010 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/27/2010 10/22/2010 Physician Belgium
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/12/2010 10/22/2010 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 9/25/2010 10/25/2010 Physician Canada
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 9/25/2010 10/26/2010 Physician Canada
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 6/28/2010 58 Male 10/27/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/5/2008 63 Male 11/5/2010 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 7/17/2009 11/8/2010 Physician Spain
Primary
Secondary

Drug Data