Folic Acid combined with Valproic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Synostosis Other Serious 6 Male 1/23/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 50 Male 2/13/2006 France
Primary
Concomitant
Syndactyly Congenital Anomaly Female 5/15/2006 Physician Spain
Primary
Secondary
Concomitant
Infection Hospitalization 4/24/2006 79 Male 107 lb 7/5/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/31/2006 62 Female 140 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Procedure Other Serious Female 9/1/2006 Physician Germany
Primary
Secondary
Concomitant
Scoliosis Hospitalization Male 5 lb 9/21/2006 Physician Germany
Primary
Secondary
Treatment Noncompliance Other Serious 8/5/2004 21 Female 10/4/2006 Physician Colombia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 23 Female 1/16/2007 Other Health Professional Chile
Primary
Concomitant
Neural Tube Defect Congenital Anomaly 3/9/2007 France
Primary
Interacting
Neural Tube Defect Congenital Anomaly 3/9/2007 France
Primary
Interacting
Neural Tube Defect Congenital Anomaly 3/9/2007 France
Primary
Interacting
Neural Tube Defect Congenital Anomaly 3/9/2007 France
Primary
Interacting
Swollen Tongue Required Intervention 7/11/2007 29 Female 178 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 8/7/2007 Female 150 lb 9/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/15/2008 72 Female 2/28/2008 Physician United States
Primary
Secondary
Concomitant
Pregnancy Induced Hypertension Hospitalization Female 5/2/2008 Consumer France
Primary
Concomitant
Grand Mal Convulsion Other Serious Female 5/2/2008 Physician France
Primary
Concomitant
Haemorrhage Other Serious 1/1/1998 Female 5/6/2008 Other Health Professional France
Primary
Concomitant
Road Traffic Accident Other Serious 12/1/1997 Female 5/8/2008 Physician France
Primary
Concomitant
Postpartum Haemorrhage Other Serious Female 5/9/2008 Physician France
Primary
Concomitant
Speech Disorder Developmental Congenital Anomaly 2/2/1999 Female 5/12/2008 Physician France
Primary
Concomitant
Protein Urine Present Other Serious 11/1/1999 Female 5/12/2008 Physician France
Primary
Concomitant
Protein Urine Present Other Serious 11/1/1999 Female 5/12/2008 Physician France
Primary
Concomitant
Grand Mal Convulsion Other Serious 1/1/2001 Female 5/19/2008 Lawyer France
Primary
Concomitant
Talipes Other Serious 6/8/2000 Female 5/21/2008 Physician France
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 11/8/2007 Male 5/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Strabismus Congenital Congenital Anomaly 7/27/2000 Female 5/23/2008 Physician France
Primary
Concomitant
Proteinuria Hospitalization 2/1/2003 Female 5/29/2008 Physician France
Primary
Concomitant
Grand Mal Convulsion Other Serious 3/1/1984 Female 5/30/2008 Physician France
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Male 6 lb 7/8/2008 Physician Mexico
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 8/26/2005 45 Female 7/20/2008 Consumer United States
Primary
Concomitant
White Blood Cell Disorder Hospitalization 1/1/2007 Male 7/22/2008 Physician France
Primary
Concomitant
Petit Mal Epilepsy Disability 7/2/2008 22 Female 119 lb 9/3/2008 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Disability 1/1/1999 Female 309 lb 11/3/2008 Consumer Netherlands
Primary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 12/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Required Intervention 12/29/2008 United Kingdom
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/8/2009 Consumer United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 2/27/2009 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 2/8/2001 43 Male 240 lb 5/20/2009 United States
Primary
Concomitant
Pancytopenia Hospitalization 5/14/2009 54 Female 264 lb 5/26/2009 Pharmacist United States
Primary
Concomitant
Apnoea Other Serious Male 7/15/2009 Other Health Professional Mexico
Primary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 8/4/2009 Physician United States
Primary
Secondary
Concomitant
Neural Tube Defect Other Serious 8/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Spina Bifida Other Serious 8/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Exfoliation Life Threatening 9/28/2009 45 Female 110 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 10/13/2009 Other Health Professional France
Primary
Secondary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 10/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Anaemia Other Serious 3/3/2008 Female 12/2/2009 Physician Italy
Primary
Secondary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 12/8/2009 Physician United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 5/29/2007 39 Female 12/11/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 12/18/2009 Physician United States
Primary
Secondary
Concomitant
Anaemia Other Serious 3/3/2008 Female 165 lb 12/22/2009 Physician Italy
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 12/28/2009 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 12/31/2009 Physician United States
Primary
Secondary
Concomitant
Anaemia Other Serious 3/3/2008 Female 165 lb 1/13/2010 Physician Italy
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 4/29/2009 56 Female 1/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Limb Malformation Congenital Anomaly 1/27/2010 United Kingdom
Primary
Secondary
Meningioma Hospitalization 9/1/2007 Male 185 lb 2/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Septal Defect Other Serious 1/1/2009 2/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Limb Malformation Other Serious 1/1/2009 2/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 1/1/2009 2/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Septal Defect Other Serious 1/1/2009 2/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Polydactyly Other Serious 1/1/2009 2/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 0 2/8/2010 France
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Limb Malformation Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Limb Malformation Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Limb Malformation Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Polydactyly Congenital Anomaly 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 2/12/2010 United Kingdom
Primary
Secondary
Death Death 12/29/2009 Female 83 lb 2/19/2010 United States
Primary
Concomitant
Ventricular Septal Defect Congenital Anomaly 2/3/2010 Physician United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus 2/6/2010 United Kingdom
Primary
Secondary
Ventricular Septal Defect 2/6/2010 United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 9/30/2009 43 Male 2/18/2010 Pharmacist United States
Primary
Concomitant
Stem Cell Transplant Death 12/29/2009 Female 83 lb 2/26/2010 United States
Primary
Concomitant
Ventricular Septal Defect 2/19/2010 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Unknown 2/19/2010 United Kingdom
Primary
Secondary
Drug Abuse Hospitalization 38 Female 3/22/2010 Physician United Kingdom
Primary
Secondary
Drug Abuse Hospitalization 38 Female 4/12/2010 Physician United Kingdom
Primary
Secondary
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 4/22/2010 Physician United States
Primary
Secondary
Concomitant
Bronchopneumonia Death 56 Female 99 lb 8/12/2010 Physician Canada
Primary
Concomitant
Skin Exfoliation Life Threatening 9/28/2009 45 Female 110 lb 8/13/2010 Pharmacist United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 43 Male 268 lb 8/27/2010 United States
Primary
Concomitant
Mental Disorder Hospitalization 4/29/2009 56 Female 9/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 10/8/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization Female 10/14/2010 Consumer United States
Primary
Concomitant
Musculoskeletal Pain Other Serious 10/1/2010 10/28/2010 Pharmacist United States
Primary
Concomitant
Haemangioma Other Serious Male 8 lb 1/5/2011 Physician United States
Primary
Concomitant
Hand Deformity Hospitalization 6/16/2008 Male 6 lb 1/31/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Agitation Neonatal Hospitalization 6/16/2008 Male 6 lb 2/2/2011 Physician Germany
Primary
Secondary
Concomitant
Feeding Disorder Neonatal Hospitalization 6/16/2008 Male 6 lb 2/7/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Agitation Neonatal Congenital Anomaly 1/1/2007 Male 6 lb 2/8/2011 Physician Germany
Primary
Secondary
Concomitant
Dysmorphism Congenital Anomaly 6/16/2008 Male 6 lb 2/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Neonatal Respiratory Distress Syndrome Congenital Anomaly 6/16/2008 Male 6 lb 2/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypotonia Neonatal Hospitalization 6/16/2008 Male 6 lb 2/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Hospitalization 1/1/2007 Male 6 lb 2/16/2011 Physician Germany
Primary
Secondary
Concomitant
Hand Deformity Congenital Anomaly 6/16/2008 Male 6 lb 2/14/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cleft Palate Congenital Anomaly 24 5/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anticonvulsant Drug Level Decreased Other Serious 12/1/2010 Female 5/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 11/11/2007 64 Male 159 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Coagulopathy Other Serious 11 Male 77 lb 6/29/2011 Pharmacist United States
Primary
Concomitant
Herpes Virus Infection Other Serious 12/1/2010 16 Female 88 lb 7/14/2011 Consumer Brazil
Primary
Concomitant
Hypoprothrombinaemia Hospitalization 11 Male 7/8/2011 Pharmacist United States
Primary
Secondary
Concomitant
Restlessness Hospitalization 11 Male 7/13/2011 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 11 Male 77 lb 7/25/2011 Other Health Professional United States
Primary
Concomitant
Coagulopathy Other Serious 11 Male 77 lb 7/27/2011 Pharmacist United States
Primary
Concomitant
Extremity Contracture Other Serious 8/4/2006 23 Female 155 lb 8/10/2011 Consumer United States
Primary
Secondary
Concomitant
Activated Partial Thromboplastin Time Prolonged Hospitalization 11 Male 77 lb 8/4/2011 Physician United States
Primary
Secondary
Concomitant
Purpura Other Serious 3/15/2011 44 Female 9/12/2011 Physician Ireland
Primary
Secondary
Concomitant
Insomnia Other Serious 8/26/2011 51 Male 9/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Other Serious 51 Male 9/21/2011 Physician United Kingdom
Primary
Concomitant
Urinary Tract Malformation Other Serious 5/1/2011 Female 6 lb 9/28/2011 Physician Germany
Primary
Secondary
Insomnia Other Serious 52 Male 9/22/2011 United Kingdom
Primary
Concomitant
Ascites Hospitalization 69 Female 10/27/2011 Physician Netherlands
Primary
Concomitant
Congenital Teratoma Congenital Anomaly 11/8/2011 Physician Turkey
Primary
Secondary
Concomitant
Spina Bifida Congenital Anomaly 11/8/2011 Physician Turkey
Primary
Secondary
Concomitant
Skin Depigmentation Other Serious 8/4/2006 23 Female 155 lb 1/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious Female 2/3/2012 Other Health Professional France
Primary
Secondary
Concomitant
Dengue Fever Hospitalization 3/1/2011 46 Female 97 lb 2/7/2012 Pharmacist Singapore
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 10/25/2011 50 Female 2/9/2012 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2011 46 Female 97 lb 2/20/2012 Pharmacist Singapore
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 10/25/2011 50 Female 2/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 10/25/2011 50 Female 2/22/2012 Physician United Kingdom
Primary
Concomitant
Alanine Aminotransferase Increased Death 1/9/2012 36 Male 2/17/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 10/25/2011 50 Female 2/29/2012 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/25/2011 50 Female 3/5/2012 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/25/2011 50 Female 3/9/2012 Pharmacist United Kingdom
Primary
Concomitant
Epilepsy Life Threatening 2/10/2012 60 3/7/2012 Other Health Professional Denmark
Primary
Concomitant
Somnolence Other Serious 10/25/2011 50 Female 3/20/2012 Pharmacist United Kingdom
Primary
Concomitant
Epilepsy Hospitalization 1/1/2005 10 Female 3/29/2012 Physician
Primary
Secondary
Concomitant
Eosinophil Count Decreased Hospitalization 10/25/2011 50 Female 3/30/2012 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/25/2011 50 Female 4/9/2012 Physician United Kingdom
Primary
Concomitant
Cardiac Murmur Hospitalization Female 6 lb 5/28/2012 Physician Germany
Primary
Secondary
Concomitant
Congenital Arterial Malformation Congenital Anomaly Female 6 lb 5/28/2012 Physician Germany
Primary
Secondary
Concomitant
Small For Dates Baby Congenital Anomaly 10/13/2011 Female 6 lb 5/29/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Small For Dates Baby Hospitalization 10/13/2011 Female 6 lb 6/4/2012 Physician Germany
Primary
Secondary
Congenital Arterial Malformation Congenital Anomaly 10/13/2011 Female 6 lb 6/5/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Small For Dates Baby Other Serious 10/13/2011 Female 6/6/2012 Other Health Professional Germany
Primary
Concomitant
Herpes Virus Infection Hospitalization 12/1/2010 16 Female 126 lb 6/25/2012 Physician Brazil
Primary
Concomitant
Infusion Related Reaction Other Serious 1/1/2012 40 Female 201 lb 6/27/2012 Other Health Professional Canada
Primary
Secondary
Concomitant

Drug Data