Folic Acid combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 10/10/2003 57 Male 160 lb 1/5/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 70 Male 1/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 6/1/2005 Female 1/31/2006 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious Male 202 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Spinal Fusion Surgery Other Serious 6/9/2003 Female 142 lb 2/10/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Life Threatening 70 Male 2/8/2006 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 63 Male 230 lb 2/16/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Life Threatening 70 Male 2/21/2006 United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 12/17/2005 60 139 lb 2/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2005 Female 3/27/2006 Physician United States
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 7/1/2005 46 Male 225 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Atrial Tachycardia Hospitalization 10/13/2005 Female 182 lb 4/24/2006 Physician United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Death 3/16/2006 81 Male 5/5/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 3/1/2006 57 Female 229 lb 4/20/2006 United States
Primary
Concomitant
Pain In Extremity 64 Female 190 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Skin Nodule Hospitalization 10/1/2003 Female 119 lb 6/22/2006 Germany
Primary
Concomitant
Pericarditis Constrictive Hospitalization 10/1/2003 Female 119 lb 7/20/2006 Germany
Primary
Concomitant
Grand Mal Convulsion 5/29/2006 41 7/18/2006 United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 9/9/2005 46 Male 1/13/2006 United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 7/28/2006 82 Female 8/25/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/22/2006 38 Male 210 lb 8/25/2006 Consumer United States
Primary
Secondary
Concomitant
Pain In Jaw 44 Female 138 lb 7/25/2006 Other Health Professional United States
Primary
Concomitant
Mobility Decreased Other Serious 6/4/2006 83 Female 9/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 6/23/2006 46 Male 9/8/2006 Other Health Professional United States
Primary
Concomitant
Optic Neuritis Other Serious Female 210 lb 9/29/2006 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 63 Female 10/3/2006 Physician Canada
Primary
Concomitant
Headache Other Serious 1/1/2005 86 Male 165 lb 10/5/2006 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/2/2006 85 Male 10/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Paraesthesia 71 Female 10/30/2006 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 9/26/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Melaena Life Threatening 8/14/2006 31 Female 11/2/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Melaena Life Threatening 8/14/2006 31 Female 137 lb 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/17/2006 Lawyer United Kingdom
Primary
Secondary
Concomitant
Melaena Life Threatening 8/14/2006 31 Female 137 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 8/3/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 9/15/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/25/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/27/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Concomitant
Pain Other Serious 8/14/2006 31 Female 137 lb 11/27/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/28/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tonsil Cancer Other Serious 1/1/2006 Female 182 lb 12/13/2006 Physician United States
Primary
Concomitant
Death Death 12/7/2006 70 Female 12/15/2006 Consumer Canada
Primary
Concomitant
Death Death 12/6/2006 70 Female 12/19/2006 Physician Canada
Primary
Concomitant
Respiratory Failure Hospitalization 11/18/2006 62 Male 187 lb 12/18/2006 Physician Spain
Primary
Secondary
Transient Ischaemic Attack Hospitalization 12/4/2005 87 Male 168 lb 12/19/2006 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 10/10/2006 64 Male 12/22/2006 Physician Germany
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Rectal Haemorrhage Required Intervention 7/11/2006 74 Female 177 lb 7/15/2006 Pharmacist United States
Primary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Rash Other Serious 10/24/2006 56 Male 210 lb 10/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 5/1/2006 Female 120 lb 1/25/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 7/25/2006 65 Male 256 lb 1/31/2007 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/19/2007 Female 138 lb 1/31/2007 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/15/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/27/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/3/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Secondary
Concomitant
Feeling Jittery 9/9/2006 76 Female 156 lb 10/16/2006 Consumer United States
Primary
Concomitant
Mobility Decreased Other Serious 6/4/2006 2/7/2007 Consumer United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/31/2007 Male 165 lb 2/9/2007 Physician
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/31/2007 Male 165 lb 2/14/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/16/2006 Male 198 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 1/24/2007 47 Male 165 lb 3/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 11/18/2006 62 NotSpecified 187 lb 3/6/2007 Physician Spain
Primary
Secondary
Septic Shock Life Threatening 1/1/2007 Male 165 lb 3/12/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 76 Female 3/14/2007 Consumer United States
Primary
Concomitant
Septic Shock Life Threatening 1/24/2007 47 Male 165 lb 3/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 3/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/31/2007 47 Male 165 lb 3/23/2007 Physician United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Melaena Life Threatening 8/14/2006 31 Female 3/20/2007 United Kingdom
Primary
Secondary
Concomitant
Duodenal Ulcer Life Threatening 8/14/2006 31 Female 137 lb 3/20/2007 United Kingdom
Primary
Secondary
Concomitant
Pollakiuria 11/1/2006 92 Female 120 lb 12/17/2006 Consumer United States
Primary
Concomitant
Rectal Prolapse Hospitalization 1/1/2006 79 Female 3/26/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/17/2007 68 Female 130 lb 3/30/2007 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 1/31/2007 47 Male 165 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 3/28/2007 United Kingdom
Primary
Secondary
Concomitant
Pain 1/1/2005 54 Female 214 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 4/13/2007 Physician Canada
Primary
Secondary
Concomitant
Rectal Prolapse Hospitalization 5/30/2006 79 Female 4/16/2007 Consumer United States
Primary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 4/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 3/1/2007 56 Female 207 lb 5/7/2007 United States
Primary
Concomitant
Fall Hospitalization 1/26/2007 Male 229 lb 5/15/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/17/2007 68 Female 96 lb 5/23/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/28/2007 60 Female 5/25/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Post Herpetic Neuralgia Other Serious 4/12/2006 73 Female 170 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bronchopneumonia Hospitalization 53 Female 220 lb 6/11/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
International Normalised Ratio Increased 10/12/2006 Male 6/26/2007 Consumer United States
Primary
Concomitant
Urticaria Other Serious 3/20/2007 70 Female 147 lb 6/13/2007 Consumer United States
Primary
Concomitant
Limb Discomfort 77 Female 6/29/2007 United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 4/21/2007 45 Female 7/10/2007 Other Health Professional Switzerland
Primary
Concomitant
Pulmonary Oedema Hospitalization 5/21/2007 76 Female 160 lb 7/10/2007 Physician United States
Primary
Concomitant
Blood Pressure Increased Other Serious 10/1/2006 82 Female 130 lb 7/9/2007 United States
Primary
Concomitant
Somnolence 3/1/2007 Female 300 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/10/2006 Male 9/4/2007 Germany
Primary
Concomitant
Pyrexia Other Serious 2/28/2007 Female 9/6/2007 Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/12/2007 67 Female 9/6/2007 Physician United States
Primary
Concomitant
Overdose Hospitalization 6/1/2007 63 Male 9/28/2007 Consumer United States
Primary
Secondary
Concomitant
Back Pain 36 Male 331 lb 9/20/2007 Consumer United States
Primary
Concomitant
Back Pain 7/1/2007 62 Female 9/20/2007 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 10/9/2007 Physician Australia
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 9/7/2007 55 Male 10/11/2007 Consumer United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 1/1/2007 Male 165 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 7/25/2006 65 Male 256 lb 10/30/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 4/15/2003 58 Female 11/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2005 Male 242 lb 11/9/2007 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 1/24/2007 47 Male 165 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 1/1/2007 Male 165 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Heart Rate Increased 6/1/2007 52 Female 11/16/2007 Consumer United States
Primary
Concomitant
Sneezing Hospitalization 7/12/2007 Female 208 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Sneezing Hospitalization 7/12/2007 Female 208 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Skin Disorder Other Serious Female 12/3/2007 Other Health Professional Canada
Primary
Concomitant
Lung Neoplasm Malignant Other Serious Female 143 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/30/2007 31 Male 265 lb 12/6/2007 Physician Australia
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2007 Female 12/10/2007 Pharmacist United States
Primary
Concomitant
Drug Ineffective 1/1/2005 Female 223 lb 12/14/2007 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/1/2007 85 Male 12/17/2007 Consumer United States
Primary
Concomitant
Overdose Hospitalization 9/1/2007 63 Male 12/17/2007 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 1/1/2007 Female 12/21/2007 Pharmacist United States
Primary
Concomitant
Melaena Required Intervention 8/14/2006 31 Female 137 lb 12/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 12/8/2007 73 Female 12/26/2007 Pharmacist United States
Primary
Concomitant
Cardiac Failure Death 12/7/2007 65 Male 1/10/2008 Other Health Professional Korea, Republic Of
Primary
Concomitant
Skin Disorder Other Serious Female 1/23/2008 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 11/1/2007 Female 130 lb 1/24/2008 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/24/2007 58 Male 252 lb 1/23/2008 United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 10/7/2003 57 Female 152 lb 1/30/2008 Physician Spain
Primary
Concomitant
Blood Pressure Increased Other Serious 1/8/2008 Male 160 lb 2/8/2008 United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 1/25/2008 Belgium
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 2/6/2008 Belgium
Primary
Concomitant
Breast Mass Other Serious 12/1/2007 58 Female 212 lb 2/19/2008 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 11/1/2006 Female 130 lb 2/21/2008 Consumer United States
Primary
Concomitant
Renal Failure Chronic Death 11/11/2007 Male 2/21/2008 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Disability 1/1/2007 86 Female 10/23/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/1/2005 75 Female 2/21/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Male 160 lb 3/21/2008 United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 10/1/2007 59 Female 185 lb 4/11/2008 United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 4/8/2008 Physician Belgium
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 4/14/2008 Lawyer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Required Intervention 9/28/2007 42 Female 4/15/2008 Pharmacist United States
Primary
Concomitant

Drug Data