Folic Acid combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Cancer Other Serious 1/1/2005 Female 154 lb 1/3/2006 Physician United States
Primary
Concomitant
Synostosis Other Serious 6 Male 1/23/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Rheumatoid Arthritis Death Male 2/10/2006 United Kingdom
Primary
Concomitant
Restlessness 10/11/2005 54 Female 1/5/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/11/2006 Female 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hip Fracture Required Intervention 52 Male 2/14/2006 Physician United States
Primary
Secondary
Concomitant
West Nile Viral Infection Other Serious 64 Male 211 lb 2/16/2006 Consumer United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 12/14/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 4/30/2005 33 Female 3/14/2006 Physician United States
Primary
Concomitant
Gait Disturbance Disability 2/1/2006 Female 4/27/2006 Other Health Professional Ireland
Primary
Concomitant
Premature Baby Hospitalization 1/1/2004 Male 15 lb 4/14/2006 Physician United States
Primary
Secondary
Therapeutic Response Decreased Other Serious 1/1/2005 Male 5/15/2006 Physician Canada
Primary
Secondary
Concomitant
Restlessness 10/11/2005 54 Female 128 lb 4/3/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 81 Female 7/7/2006 Canada
Primary
Secondary
Concomitant
Hypotension Other Serious 5/8/2006 80 Male 166 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 8/1/2006 47 Male 166 lb 8/14/2006 United States
Primary
Secondary
Concomitant
Purple Glove Syndrome Other Serious 8/1/2006 47 Male 166 lb 8/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 6/2/2006 36 Female 334 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 9/1/2006 63 Male 249 lb 9/6/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 5/21/2006 55 Female 225 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 8/4/2005 33 Female 9/21/2006 Physician United States
Primary
Concomitant
Pregnancy Other Serious 11/4/2005 23 Female 9/29/2006 United States
Primary
Concomitant
Paraesthesia 5/11/2006 35 Male 8/10/2006 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 7/27/2006 NotSpecified 10/13/2006 Physician United States
Primary
Concomitant
Nystagmus Hospitalization 9/5/2006 52 Male 10/26/2006 United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 7/27/2006 Female 2/5/2007 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Hospitalization 12/11/2006 83 Male 2/16/2007 Pharmacist United States
Primary
Concomitant
Sudden Death Hospitalization 12/31/2006 74 Female 2/12/2007 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 11/4/2005 23 Female 2/28/2007 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 8/4/2005 33 Female 3/27/2007 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 7/27/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Sudden Death Hospitalization 12/31/2006 74 Female 4/2/2007 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 7/27/2006 Female 4/5/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 83 Female 118 lb 5/18/2007 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 1/1/2007 83 Female 118 lb 6/8/2007 Consumer Canada
Primary
Concomitant
Premature Baby Congenital Anomaly 7/27/2006 Female 6 lb 6/29/2007 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/4/2005 33 Female 7/2/2007 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 4/18/2004 31 Female 7/9/2007 United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 6/27/2007 75 Male 165 lb 7/9/2007 United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 6/27/2007 75 Male 165 lb 7/16/2007 Consumer United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Other Serious 6/1/2007 Male 180 lb 7/23/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/24/2007 81 Female 120 lb 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Ectopic Pregnancy Other Serious 12/23/1999 30 Female 10/24/2007 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 1/1/2007 55 Female 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 1/1/2007 55 Female 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Other Serious Female 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Muscular Weakness Congenital Anomaly 7/27/2006 Female 6 lb 1/2/2008 Physician United States
Primary
Concomitant
Fall Hospitalization 10/26/2007 69 Male 146 lb 1/11/2008 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 11/15/2007 Male 165 lb 1/18/2008 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious Female 225 lb 2/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 11/15/2007 Male 165 lb 3/1/2008 Physician United Kingdom
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 6/1/2007 59 Female 3/6/2008 Consumer Australia
Primary
Concomitant
Somnolence 12/21/2007 Female 172 lb 3/14/2008 Consumer United States
Primary
Concomitant
Skin Papilloma Other Serious 1/26/2007 30 Female 4/28/2008 Physician France
Primary
Concomitant
Transaminases Increased Hospitalization 9/3/2007 72 Female 5/16/2008 Other Health Professional Singapore
Primary
Concomitant
Grand Mal Convulsion Other Serious 3/1/1984 Female 5/30/2008 Physician France
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious Female 6/2/2008 Physician France
Primary
Secondary
Concomitant
Neutropenia Disability 4/1/2008 56 Male 130 lb 5/27/2008 Pharmacist United States
Primary
Concomitant
Injection Site Pain 12/1/2007 Female 240 lb 6/12/2008 United States
Primary
Concomitant
Cellulitis 4/10/2008 Female 248 lb 6/12/2008 United States
Primary
Concomitant
Dyspnoea Death 5/10/2008 Female 104 lb 6/19/2008 Physician United States
Primary
Concomitant
Rib Fracture Other Serious 1/1/2007 Female 125 lb 6/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Maternal Drugs Affecting Foetus Congenital Anomaly Male 5 lb 7/9/2008 Physician Mexico
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Female 7 lb 7/9/2008 Physician Mexico
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Male 6 lb 7/8/2008 Physician Mexico
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Female 6 lb 7/8/2008 Physician Mexico
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Female 7 lb 7/28/2008 Physician Mexico
Primary
Secondary
Concomitant
Speech Disorder Developmental Hospitalization 1/1/2004 0 Male 15 lb 8/8/2008 Belgium
Primary
Secondary
Unresponsive To Stimuli Hospitalization 5/14/2008 72 Male 9/3/2008 Pharmacist United States
Primary
Concomitant
Speech Disorder Developmental Congenital Anomaly Female 7 lb 9/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/4/2003 12 Female 10/16/2008 France
Primary
Concomitant
Muscular Weakness Congenital Anomaly 7/27/2006 Female 6 lb 1/23/2009 Physician United States
Primary
Concomitant
Flushing 2/1/2009 Female 2/24/2009 United States
Primary
Concomitant
Rash Pruritic 2/1/2009 Male 5/4/2009 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 4/30/2009 80 Male 5/22/2009 Consumer
Primary
Concomitant
Myocardial Infarction Other Serious 11/15/2008 Male 5/27/2009 Consumer United Kingdom
Primary
Concomitant
Respiratory Distress Hospitalization Male 7 lb 6/5/2009 Physician Australia
Primary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 7/14/2009 Physician United Kingdom
Primary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 8/4/2009 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 31 Female 9/7/2009 Physician United States
Primary
Secondary
Concomitant
Cellulitis 4/10/2008 Female 248 lb 9/12/2009 United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 5/9/1996 Male 9/23/2009 Physician
Primary
Secondary
Ventricular Extrasystoles Hospitalization 5/9/1996 Male 10/7/2009 Physician
Primary
Secondary
Tremor Hospitalization 9/13/2009 39 Female 9/14/2009 Pharmacist United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 12/18/2009 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 12/28/2009 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 12/31/2009 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 80 Female 1/14/2010 United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/1/2007 60 Male 3/18/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment 5/21/2008 53 Male 4/12/2010 Consumer United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 4/22/2010 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 7/1/2008 65 Male 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization Male 7 lb 5/10/2010 Physician Sweden
Primary
Concomitant
Pneumonia Mycoplasmal Hospitalization 2/18/2010 40 Female 102 lb 5/4/2010 Other Health Professional Japan
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 73 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/1/2007 60 Male 6/15/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Infection Other Serious 9/6/2001 49 Female 217 lb 8/5/2010 United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 72 Male 8/5/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Infection Other Serious 9/6/2001 49 Female 217 lb 8/12/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 8/13/2010 United States
Primary
Concomitant
Cholecystitis Acute Other Serious 8/26/2010 47 Female 9/2/2010 Other Health Professional Argentina
Primary
Secondary
Concomitant
Somnolence 5/23/2010 33 Female 9/8/2010 Other Health Professional Ireland
Primary
Concomitant
Vaginal Infection Other Serious 9/6/2001 49 Female 217 lb 9/17/2010 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 11/1/2007 60 Male 9/30/2010 Other Health Professional United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 8/4/2006 23 Female 154 lb 10/8/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 10/13/2010 United States
Primary
Concomitant
Somnolence Other Serious 5/23/2010 33 Female 10/21/2010 Other Health Professional Ireland
Primary
Concomitant
Rash Erythematous Other Serious 10/19/2010 72 Male 11/17/2010 Physician Switzerland
Primary
Secondary
Concomitant
Product Quality Issue 5/19/2010 57 Male 247 lb 10/28/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Life Threatening 40 Male 12/3/2010 Consumer Switzerland
Primary
Secondary
Concomitant
Thermal Burn Other Serious 6/1/2010 38 Male 250 lb 12/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/22/2010 40 Male 12/8/2010 Switzerland
Primary
Secondary
Concomitant
Ill-defined Disorder Other Serious 1/1/2000 50 Male 215 lb 1/24/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/1/2010 62 Female 1/29/2011 Physician United States
Primary
Concomitant
Depression Other Serious 6/1/2010 38 Male 250 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Other Serious 1/1/2000 Male 215 lb 2/15/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Papilloma Other Serious 2/19/2008 30 Female 3/17/2011 Physician France
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Death 12/7/2010 79 Male 5/6/2011 Other Health Professional France
Primary
Secondary
Concomitant
Migraine 4/24/2008 53 Male 5/9/2011 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 6/1/2010 39 Male 250 lb 3/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 11/4/2008 82 Male 110 lb 5/30/2011 Consumer Brazil
Primary
Concomitant
Granulocytopenia Other Serious 8/18/2010 19 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Pain Other Serious 80 Female 6/20/2011 United States
Primary
Concomitant
Death Death 2/10/2011 89 Female 7/14/2011 Consumer Switzerland
Primary
Concomitant
Malaise 10/1/2010 66 Female 170 lb 7/17/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2008 64 Female 130 lb 7/20/2011 Lawyer United States
Primary
Concomitant
Extremity Contracture Other Serious 8/4/2006 23 Female 155 lb 8/10/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Effect Decreased 8/12/2011 61 Male 310 lb 8/18/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Homocysteine Increased Other Serious 61 Male 8/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Electrocardiogram St-t Change Hospitalization 6/29/2011 84 Female 130 lb 9/14/2011 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 4/23/2008 48 Male 138 lb 9/12/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious Female 90 lb 9/27/2011 Physician United States
Primary
Concomitant
Insomnia Other Serious 52 Male 9/22/2011 United Kingdom
Primary
Concomitant
Haemorrhage Female 11/3/2011 Other Health Professional United States
Primary
Concomitant
Sepsis Death 1/1/2008 64 Female 130 lb 11/8/2011 United States
Primary
Concomitant
Injection Site Warmth 1/17/2011 75 Female 130 lb 11/17/2011 Consumer United States
Primary
Concomitant
Ulcer Hospitalization 1/1/2011 63 Female 90 lb 12/2/2011 Consumer United States
Primary
Concomitant
Thrombophlebitis Hospitalization 1/17/2011 36 Female 12/5/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 1/17/2011 36 Female 12/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Other Serious Female 12/7/2011 Lawyer United States
Primary
Concomitant
Abdominal Pain Hospitalization 9/1/2003 46 Male 130 lb 1/2/2012 Physician United States
Primary
Secondary
Concomitant
Skin Depigmentation Other Serious 8/4/2006 23 Female 155 lb 1/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Macular 11/1/2011 56 Female 1/29/2012 Consumer United States
Primary
Concomitant
Paraesthesia 11/21/2011 56 Female 1/29/2012 Consumer United States
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 9/1/2003 46 Male 130 lb 2/1/2012 Lawyer United States
Primary
Secondary
Concomitant
Application Site Rash Death 11/4/2008 82 Male 110 lb 2/2/2012 Consumer Brazil
Primary
Concomitant
Drug Interaction Other Serious 9/1/2011 52 Male 150 lb 2/3/2012 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 8/1/2011 66 Female 214 lb 2/26/2012 Consumer Brazil
Primary
Concomitant
Haemoglobin Decreased Other Serious 53 Male 2/28/2012 Physician United States
Primary
Concomitant
Rash Macular Hospitalization 9/1/2003 46 Male 130 lb 3/6/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data