Folic Acid combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 12/25/2005 57 Male 235 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Prostate Examination Abnormal Hospitalization 10/1/2005 Male 253 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/12/2006 58 Male 300 lb 1/12/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2001 55 Female 148 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2001 54 Female 185 lb 2/22/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/10/2005 71 Male 250 lb 12/27/2005 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 3/2/2004 45 Male 196 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 9/29/1999 70 Male 209 lb 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 2/13/2006 Male 4/5/2006 Physician Canada
Primary
Concomitant
Vomiting 11/11/2005 46 Female 220 lb 1/20/2006 Consumer United States
Primary
Concomitant
Nausea 10/4/2005 70 Female 189 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 11/10/2005 78 Female 204 lb 1/20/2006 Consumer United States
Primary
Concomitant
Death Other Serious Female 185 lb 4/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemic Coma Hospitalization 3/5/2006 53 Female 4/10/2006 Switzerland
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2003 75 Male 183 lb 4/24/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 8/2/2003 52 Male 276 lb 4/28/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 3/2/2004 45 Male 196 lb 5/1/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2006 64 Male 4/15/2006 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 76 Male 4/24/2006 New Zealand
Primary
Concomitant
Injection Site Irritation Hospitalization Female 5/2/2006 Consumer United States
Primary
Concomitant
Therapy Non-responder Other Serious 7/1/2003 52 Male 4/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 57 Male 5/9/2006 Australia
Primary
Concomitant
Tremor Other Serious 74 Male 291 lb 5/11/2006 United States
Primary
Secondary
Concomitant
Pain Other Serious 5/1/2005 66 Male 5/12/2006 Canada
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 7/1/2005 Male 5/12/2006 Physician United States
Primary
Concomitant
Somnolence 1/1/2005 Male 5/12/2006 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 65 Male 5/3/2006 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 12/28/2005 76 Male 200 lb 2/2/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 3/7/2006 74 Male 291 lb 5/19/2006 United States
Primary
Secondary
Concomitant
Candidiasis Hospitalization 9/16/2005 Female 178 lb 5/25/2006 Physician United States
Primary
Concomitant
Extrasystoles Other Serious 1/1/2006 69 Male 5/15/2006 Physician Canada
Primary
Concomitant
Heart Rate Irregular Other Serious 1/1/2006 63 Male 226 lb 5/30/2006 United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/7/2006 74 Male 291 lb 5/24/2006 United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious Female 185 lb 6/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Other Serious 11/1/2005 Male 200 lb 4/20/2006 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 10/1/2003 Female 294 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngitis 55 Female 3/17/2006 Consumer United States
Primary
Concomitant
Mass Required Intervention 1/18/2006 61 Female 200 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization Male 225 lb 6/23/2006 Other Health Professional Canada
Primary
Concomitant
Salivary Duct Obstruction Hospitalization 5/15/2006 53 Female 173 lb 6/27/2006 Physician United States
Primary
Secondary
Concomitant
Injection Site Bruising 8/8/2005 76 Female 200 lb 4/17/2006 Consumer United States
Primary
Concomitant
Urticaria 2/1/2006 37 Female 206 lb 4/17/2006 Physician United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 4/10/2006 56 Female 182 lb 6/26/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 1/7/2006 49 Female 200 lb 4/17/2006 Consumer United States
Primary
Concomitant
Confusional State Other Serious Female 185 lb 7/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gamma-glutamyltransferase Increased Disability 5/4/2006 Male 265 lb 7/10/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Life Threatening 1/1/2006 69 Female 132 lb 7/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/30/2006 69 Female 132 lb 7/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 5/5/2006 56 Male Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/12/2006 76 Male 7/14/2006 Other Health Professional New Zealand
Primary
Concomitant
Myalgia 75 Female 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2005 78 Male 7/21/2006 Consumer United States
Primary
Concomitant
Dysgeusia 1/1/2006 60 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 1/30/2006 7/19/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 1/30/2006 69 Female 132 lb 7/20/2006 United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Eye Inflammation Other Serious 7/19/2006 51 Female 8/2/2006 Consumer United States
Primary
Concomitant
Vasodilatation Other Serious 1/1/2000 70 Female 140 lb 7/28/2006 United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 1/24/2006 Male 8/4/2006 Other Health Professional United States
Primary
Concomitant
Vaginal Cancer Other Serious 7/1/2006 Female 155 lb 8/7/2006 Other Health Professional United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 2/13/2006 Female 185 lb 8/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Endometrial Cancer Stage Ii Other Serious 5/2/2006 64 Female 8/7/2006 Consumer United States
Primary
Concomitant
Hyperkalaemia Other Serious 4/3/2006 61 Male 8/22/2006 Pharmacist Australia
Primary
Concomitant
Urinary Tract Infection Other Serious 6/2/2005 Female 185 lb 8/23/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 71 Female 8/18/2006 Denmark
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 2/13/2006 Female 185 lb 8/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vasodilatation Other Serious 1/1/2000 70 Female 141 lb 9/1/2006 Consumer United States
Primary
Secondary
Concomitant
Tooth Abscess 4/11/2006 70 Male 230 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 60 Female 230 lb 9/8/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 7/10/2006 74 Female 187 lb 9/6/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Death 8/18/2006 71 Female 9/20/2006 Physician Thailand
Primary
Concomitant
Renal Failure Acute Hospitalization 8/8/2006 71 Female 9/25/2006 Physician Thailand
Primary
Concomitant
Ventricular Extrasystoles Other Serious 1/1/2006 69 Male 145 lb 9/15/2006 Physician Canada
Primary
Concomitant
Coronary Artery Disease Hospitalization Male 225 lb 10/6/2006 Other Health Professional Canada
Primary
Concomitant
Vaginal Cancer Other Serious 7/1/2006 Female 155 lb 10/9/2006 Other Health Professional United States
Primary
Concomitant
Arthropathy Other Serious Female 149 lb 10/9/2006 Consumer Canada
Primary
Concomitant
Syncope Other Serious 9/21/2006 73 Male 243 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 10/23/2006 46 Female 11/13/2006 Other Health Professional Thailand
Primary
Concomitant
Sedation Female 11/13/2006 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iii Other Serious 8/31/2006 Female 150 lb 11/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2006 Female 160 lb 11/16/2006 Consumer United States
Primary
Concomitant
Hypokalaemia Hospitalization 10/31/2006 Female 11/22/2006 Consumer United States
Primary
Concomitant
Gastric Ulcer Other Serious 10/20/2006 Female 181 lb 12/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 3/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/26/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 12/11/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/20/2006 Male 230 lb 12/11/2006 Physician United States
Primary
Concomitant
Injection Site Pain 5/1/2006 Female 12/20/2006 Pharmacist United States
Primary
Concomitant
Pubic Rami Fracture Other Serious 8/1/2006 66 Male 206 lb 1/9/2007 Consumer United States
Primary
Secondary
Concomitant
Faecal Incontinence Hospitalization 1/11/2007 80 Male 159 lb 1/25/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 2/12/2007 Consumer United States
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 4/3/2006 61 Male 2/14/2007 Pharmacist Australia
Primary
Concomitant
Papilloedema Hospitalization 1/1/2006 220 lb 2/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hysterectomy Other Serious 11/1/2006 43 Female 3/10/2007 United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 8/1/2006 65 Male 270 lb 11/28/2006 United States
Primary
Concomitant
Lactic Acidosis Hospitalization 1/1/2005 72 Female 4/5/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Motor Neurone Disease Other Serious Male 187 lb 4/16/2007 Physician United Kingdom
Primary
Concomitant
Urine Output Decreased Life Threatening 2/12/2007 57 Male 181 lb 4/26/2007 Physician Canada
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 8/14/2006 66 Female 6/25/2007 United States
Primary
Concomitant
Death Disability 3/1/2007 80 Female 90 lb 7/9/2007 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Intestinal Haemorrhage Hospitalization Male 54 lb 8/23/2007 Pharmacist United States
Primary
Concomitant
Somnolence 3/1/2007 Female 300 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Fungal Infection Other Serious 11/27/2006 Female 200 lb 9/7/2007 Consumer Canada
Primary
Concomitant
Hemianopia Homonymous Other Serious 4/17/2007 Female 9/11/2007 Physician United States
Primary
Concomitant
Chills Other Serious 11/1/2006 68 Female 9/17/2007 Consumer United States
Primary
Concomitant
Feeling Hot 72 Female 119 lb 9/20/2007 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 8/29/2007 47 Female 119 lb 9/28/2007 Physician United States
Primary
Concomitant
Fluid Retention Other Serious 10/1/2007 Female 255 lb 10/23/2007 United States
Primary
Concomitant
Polyarthritis Other Serious 9/19/2007 Male 10/24/2007 Physician Netherlands
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution 55 Female 10/23/2007 Consumer United States
Primary
Concomitant
Regurgitation Other Serious 7/20/2007 Male 175 lb 10/26/2007 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 68 Male 209 lb 12/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/25/2007 37 Male 185 lb 1/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 6/15/2007 Female 20 lb 1/21/2008 United Kingdom
Primary
Concomitant
Localised Infection Other Serious 10/3/2006 Male 157 lb 1/21/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/20/2008 Female 110 lb 3/3/2008 Physician United States
Primary
Concomitant
Jaundice Hospitalization 10/17/2007 Male 7 lb 3/13/2008 Consumer Brazil
Primary
Concomitant
Pain In Extremity 8/19/2007 Female 150 lb 3/14/2008 Consumer United States
Primary
Concomitant
Smear Cervix Abnormal 3/10/2007 Female 178 lb 3/15/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 8/1/2007 Female 172 lb 3/15/2008 United States
Primary
Concomitant
Procedural Complication 2/25/2008 Female 190 lb 3/15/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2008 Female 135 lb 3/15/2008 Consumer United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 2/1/2008 Female 122 lb 3/24/2008 Physician United States
Primary
Concomitant
Jaundice Neonatal Hospitalization 10/17/2007 Male 7 lb 3/26/2008 Consumer Brazil
Primary
Concomitant
Weight Decreased 5/1/2005 Female 198 lb 6/5/2008 Physician United States
Primary
Concomitant
Peripheral Vascular Disorder 8/1/2005 Female 198 lb 6/5/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity 62 Male 6/23/2008 United States
Primary
Concomitant
Rash Other Serious 4/7/2008 Female 161 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 5/1/2008 Female 199 lb 6/30/2008 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious Female 178 lb 7/16/2008 Physician United States
Primary
Concomitant
Pyrexia 6/23/2008 Female 186 lb 7/24/2008 Other Health Professional United States
Primary
Concomitant
Blood Homocysteine Increased 65 Male 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Heart Rate Increased 1/1/1999 53 Female 7/24/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 136 lb 7/21/2008 Physician United States
Primary
Concomitant
Throat Cancer Other Serious 1/18/2008 Male 181 lb 8/22/2008 United Kingdom
Primary
Concomitant
Splenomegaly Hospitalization 1/1/2007 Female 259 lb 8/18/2008 Physician United States
Primary
Concomitant
Rhinorrhoea 3/1/2008 70 Male 8/15/2008 United States
Primary
Concomitant
Palpitations Other Serious 1/1/2008 63 Female 297 lb 8/22/2008 United States
Primary
Concomitant
Convulsion Other Serious 8/30/2008 Female 9/9/2008 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 7/2/2007 61 Male 198 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 11/1/2006 Female 164 lb 9/3/2008 Physician United States
Primary
Concomitant
Convulsion Other Serious 9/3/2008 Female 10/28/2008 Physician United States
Primary
Concomitant
Rash 8/9/2008 56 Female 12/11/2008 Physician Canada
Primary
Secondary
Concomitant
Pancreatitis Other Serious 11/15/2008 74 Female 139 lb 12/12/2008 Physician United States
Primary
Concomitant
Synovitis Other Serious 10/1/2008 67 Male 203 lb 12/19/2008 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data