Folic Acid combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vertigo Hospitalization 11/16/2002 Male 1/4/2006 France
Primary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Yellow Skin Other Serious 6/27/2005 40 Female 176 lb 1/10/2006 United States
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 1/15/2006 Female 154 lb 4/12/2006 Other Health Professional Netherlands
Primary
Concomitant
Malignant Melanoma Other Serious 6/16/2001 52 Male 209 lb 4/24/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2001 52 Male 209 lb 5/1/2006 Physician United States
Primary
Concomitant
Pleural Effusion Life Threatening 1/27/2006 45 Female 5/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling 4/24/2006 Male 418 lb 6/30/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 79 Female 154 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 73 Female 139 lb 8/1/2006 Consumer United States
Primary
Concomitant
Pregnancy Other Serious 22 Female 8/8/2006 Denmark
Primary
Concomitant
Renal Failure Chronic Other Serious 1/30/2006 69 Female 8/21/2006 Denmark
Primary
Concomitant
Renal Failure Acute Hospitalization 9/6/2004 Male 214 lb 9/7/2006 Australia
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 7/18/2006 58 Male 419 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 8/17/2006 Female 3/9/2007 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection Disability 1/22/2007 59 Female 187 lb 5/29/2007 Physician United Kingdom
Primary
Concomitant
Hypotension Hospitalization 9/22/2006 Male 12/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/18/2008 74 Female 112 lb 3/18/2008 Physician
Primary
Concomitant
Fatigue Other Serious 50 Female 268 lb 3/28/2008 Other Health Professional United States
Primary
Concomitant
Myalgia Other Serious 7/1/2007 69 Male 205 lb 4/30/2008 United States
Primary
Concomitant
Hypoplastic Left Heart Syndrome Other Serious 0 7/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 9/17/2008 58 Female 210 lb 10/13/2008 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/16/2008 Male 225 lb 10/21/2008 United Kingdom
Primary
Concomitant
Medication Error 9/19/2008 Male 211 lb 10/6/2008 Pharmacist United States
Primary
Concomitant
Pregnancy Other Serious 22 Female 10/22/2008 Physician Denmark
Primary
Concomitant
Renal Failure Chronic Other Serious 1/30/2006 69 Female 10/22/2008 Denmark
Primary
Concomitant
Death Other Serious Female 150 lb 10/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Other Serious 2/13/2008 63 Male 214 lb 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 12/15/2008 Male 143 lb 1/9/2009 Consumer Brazil
Primary
Concomitant
Somnolence Other Serious 12/15/2008 Male 143 lb 1/28/2009 Consumer Brazil
Primary
Concomitant
Dyspepsia Hospitalization 10/27/2008 2/18/2009 Physician United Kingdom
Primary
Concomitant
Plantar Fasciitis 6/1/2007 Female 220 lb 3/14/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/15/2008 65 Male 5/15/2009 United States
Primary
Concomitant
Vertigo Hospitalization 4/18/2009 52 Female 208 lb 5/23/2009 Consumer Israel
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 Male 194 lb 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Procedural Complication 6/1/2008 Female 230 lb 6/11/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2008 Male 289 lb 6/11/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 10/1/2005 Female 150 lb 6/11/2009 United States
Primary
Concomitant
Injection Site Irritation 3/1/2008 Female 140 lb 6/12/2009 Consumer United States
Primary
Concomitant
Swelling Face 1/1/2009 Female 285 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Pain 3/3/2009 Male 264 lb 6/12/2009 United States
Primary
Concomitant
Vision Blurred Female 170 lb 6/12/2009 Physician United States
Primary
Concomitant
Vertebral Injury 4/1/2009 Female 135 lb 6/12/2009 United States
Primary
Concomitant
Myalgia 1/1/2008 Male 210 lb 6/12/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain 4/29/2009 Female 205 lb 6/12/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 5/12/2009 Female 240 lb 6/12/2009 Consumer United States
Primary
Concomitant
Paraesthesia Female 6/15/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 3/1/2009 Male 197 lb 6/15/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/7/2009 60 Male 134 lb 6/30/2009 Pharmacist United States
Primary
Concomitant
Rash Pruritic Hospitalization 6/20/2009 77 Female 7/1/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 6/14/2008 Female 223 lb 9/12/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 50 Male 354 lb 9/22/2009 United States
Primary
Concomitant
C-reactive Protein Increased Hospitalization 9/22/2009 59 Female 198 lb 10/12/2009 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 8/30/2009 41 Female 198 lb 10/13/2009 Other Health Professional Singapore
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 76 Male 174 lb 10/5/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 7/6/2009 Female 123 lb 10/14/2009 Physician Malaysia
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2008 Female 226 lb 10/14/2009 Canada
Primary
Concomitant
C-reactive Protein Increased Hospitalization 9/24/2009 Female 198 lb 10/14/2009 Physician Netherlands
Primary
Secondary
Concomitant
Foot Deformity Other Serious Female 190 lb 10/16/2009 Other Health Professional Canada
Primary
Concomitant
C-reactive Protein Increased Hospitalization 9/22/2009 59 Female 198 lb 10/19/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Female 139 lb 11/5/2009 Physician United States
Primary
Concomitant
Rash Maculo-papular Death 10/7/2009 77 Female 11/25/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 204 lb 11/30/2009 Consumer United States
Primary
Concomitant
Dyspepsia Hospitalization 10/27/2008 68 Female 12/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Female 139 lb 12/14/2009 Physician United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 8/1/2008 78 Male 250 lb 12/22/2009 Physician United States
Primary
Concomitant
Malnutrition Hospitalization 11/18/2009 Female 12/23/2009 Physician Japan
Primary
Concomitant
Uveitis Other Serious 2/5/2008 Male 175 lb 1/11/2010 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/9/2009 Male 191 lb 1/12/2010 Physician Sweden
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Female 139 lb 1/13/2010 Physician United States
Primary
Concomitant
Quadriparesis Hospitalization 1/1/2010 Female 1/15/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/14/2009 Female 1/19/2010 United States
Primary
Concomitant
Muscular Weakness Other Serious 10/6/2009 Female 1/21/2010 Physician Germany
Primary
Concomitant
Swelling Other Serious 1/1/2010 Female 155 lb 1/27/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant
Pneumonia Other Serious 2/1/2010 77 Female 2/17/2010 Consumer Canada
Primary
Concomitant
Thrombocytopenia Other Serious 8/1/2009 Female 2/18/2010 Physician Canada
Primary
Concomitant
Thrombocytopenia Life Threatening 8/1/2009 Female 2/18/2010 Physician Canada
Primary
Secondary
Concomitant
Wheezing 1/16/2009 43 Female 2/26/2010 Consumer United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 4/1/2009 65 Female 174 lb 3/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Haemolysis Hospitalization 7/1/2008 68 Female 218 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 9/1/2009 52 Female 1/28/2010 Consumer United States
Primary
Concomitant
Underdose Hospitalization 6/1/2009 Male 3/2/2010 Physician United States
Primary
Concomitant
Coronary Artery Bypass Hospitalization Female 127 lb 3/3/2010 Consumer United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 8/1/2008 78 Male 250 lb 3/9/2010 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 65 Male 223 lb 3/11/2010 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 12/1/2007 Male 200 lb 3/17/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 3/18/2010 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/29/2010 Female 210 lb 3/22/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Death 1/14/2010 78 Male 3/25/2010 Physician Denmark
Primary
Concomitant
Pulmonary Embolism Life Threatening 3/29/2010 56 Male 181 lb 4/6/2010 Physician Turkey
Primary
Secondary
Concomitant
Sudden Death Life Threatening 3/29/2010 56 Male 181 lb 4/15/2010 Physician Turkey
Primary
Secondary
Concomitant
Toothache Other Serious 11/1/2009 70 Female 149 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Sudden Death Life Threatening 3/29/2010 56 Male 181 lb 5/7/2010 Physician Turkey
Primary
Secondary
Concomitant
Mixed Hepatocellular Cholangiocarcinoma Life Threatening Male 5/10/2010 Other Health Professional Germany
Primary
Concomitant
Hospitalisation Hospitalization 1/1/2009 71 Female 5/11/2010 Canada
Primary
Concomitant
Speech Disorder Other Serious 12/1/2009 73 Female 198 lb 5/11/2010 Physician Brazil
Primary
Concomitant
H1n1 Influenza Other Serious 7/2/2009 53 Female 148 lb 5/13/2010 Other Health Professional Chile
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 4/8/2010 78 Female 142 lb 5/14/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/5/2010 54 Male 199 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/8/2010 59 Female 165 lb 5/15/2010 Physician Brazil
Primary
Concomitant
Infection Other Serious 3/1/2010 67 Male 5/17/2010 Other Health Professional United States
Primary
Concomitant
Nausea 1/26/2010 50 Female 4/19/2010 Consumer United States
Primary
Concomitant
Pruritus Female 160 lb 5/17/2010 United States
Primary
Concomitant
Pruritus 3/28/2010 67 Female 200 lb 5/17/2010 United States
Primary
Concomitant
Paraesthesia 4/13/2010 56 Female 196 lb 5/17/2010 Consumer United States
Primary
Concomitant
Flushing 5/2/2009 69 Female 214 lb 5/17/2010 United States
Primary
Concomitant
Small Intestinal Perforation Hospitalization 60 Female 285 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 12/27/2008 54 Male 216 lb 5/18/2010 Physician Canada
Primary
Secondary
Concomitant
Psoriatic Arthropathy Other Serious 1/1/2009 65 Male 170 lb 5/18/2010 Canada
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 64 Male 194 lb 5/20/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 5/8/2010 47 Female 235 lb 5/11/2010 Physician United States
Primary
Concomitant
Ulcerative Keratitis Other Serious 4/12/2010 54 Female 184 lb 5/21/2010 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 62 Male 243 lb 5/17/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/24/2010 64 Female 211 lb 5/21/2010 Other Health Professional United States
Primary
Concomitant
Psoriasis Life Threatening 3/3/2010 62 Male 5/27/2010 Physician Brazil
Primary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 5/28/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 12/27/2008 54 Male 216 lb 5/28/2010 Physician Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 6/10/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 6/17/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 7/26/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 5/25/2004 45 Female 117 lb 8/4/2010 Consumer Brazil
Primary
Concomitant
Urinary Retention Hospitalization 1/15/2010 74 Male 225 lb 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombotic Stroke Other Serious 1/1/2009 57 Female 139 lb 9/28/2010 Other Health Professional United States
Primary
Concomitant
Pancytopenia Hospitalization 7/31/2010 51 Female 100 lb 9/21/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 9/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 10/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/27/2010 52 Female 110 lb 10/29/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Pancytopenia Hospitalization 7/31/2010 51 Female 100 lb 10/29/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 11/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Life Threatening 12/8/2010 66 Male 117 lb 12/17/2010 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Other Serious 12/20/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/31/2010 51 Female 100 lb 12/17/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Peritonitis Other Serious 12/8/2010 66 Male 117 lb 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Other Serious 12/8/2010 66 Male 117 lb 1/4/2011 Physician Japan
Primary
Secondary
Concomitant
Vomiting 12/1/2010 Male 1/7/2011 Consumer
Primary
Concomitant
Dry Eye 2/1/2010 61 Female 170 lb 1/28/2011 Consumer United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/16/2011 56 Female 2/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/15/2009 77 Male 186 lb 2/9/2011 Physician United States
Primary
Concomitant
Packed Red Blood Cell Transfusion Hospitalization 1/13/2011 80 Female 2/14/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2007 66 Female 136 lb 2/24/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenic Colitis Hospitalization 3/4/2010 69 Male 211 lb 2/25/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/9/2010 51 Female 108 lb 3/16/2011 United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/2/2011 59 Female 3/18/2011 Consumer United States
Primary
Concomitant
Wound Dehiscence Hospitalization 11/13/2007 55 Female 176 lb 4/4/2011 Physician Brazil
Primary
Concomitant
Injection Site Haematoma Other Serious 4/1/2011 44 Female 185 lb 5/3/2011 Consumer Brazil
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 12/28/2006 57 Female 228 lb 5/3/2011 Physician United States
Primary
Concomitant

Drug Data