Folic Acid combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Hospitalization 6/30/2005 Female 1/23/2006 Germany
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2006 Female 155 lb 2/1/2006 Canada
Primary
Concomitant
Muscle Spasms Hospitalization 12/9/2005 Female 176 lb 2/2/2006 Canada
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 2/3/2006 Germany
Primary
Concomitant
Psoriasis Other Serious 8/4/2005 Female 120 lb 2/6/2006 Canada
Primary
Concomitant
Peridiverticular Abscess Hospitalization 1/1/2006 Female 155 lb 2/17/2006 Physician Canada
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 3/9/2006 Physician Germany
Primary
Concomitant
Pulmonary Function Test Decreased Hospitalization 1/1/2004 75 Male 3/11/2006 United Kingdom
Primary
Concomitant
Hip Surgery Hospitalization 12/7/2005 51 Female 3/13/2006 Consumer Canada
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 4/4/2006 Physician Germany
Primary
Concomitant
Sepsis Hospitalization Female 4/10/2006 Physician Germany
Primary
Concomitant
Sepsis Hospitalization Female 4/17/2006 Physician Germany
Primary
Concomitant
Respiratory Tract Infection Hospitalization 11/15/2005 Male 122 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Other Serious 12/1/2005 Female 120 lb 5/8/2006 Consumer Canada
Primary
Concomitant
Streptococcal Infection Hospitalization Female 5/9/2006 Physician Germany
Primary
Concomitant
Hospitalisation Hospitalization Female 170 lb 5/12/2006 Consumer Canada
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/11/2006 Male 5/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 8/1/2005 67 Female 168 lb 1/11/2006 Physician United States
Primary
Concomitant
Hip Arthroplasty Hospitalization 5/5/2006 Female 140 lb 6/7/2006 Consumer Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 4/21/2006 Female 170 lb 6/21/2006 Consumer Canada
Primary
Concomitant
Thrombosis Hospitalization 1/1/2003 62 Female 7/13/2006 Consumer Australia
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2003 Female 178 lb 7/26/2006 Consumer United States
Primary
Concomitant
Thyroid Neoplasm Life Threatening 4/21/2006 Female 167 lb 8/4/2006 Other Health Professional Canada
Primary
Concomitant
Arterial Occlusive Disease Other Serious 6/29/2006 Male 209 lb 8/4/2006 Consumer Canada
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 8/10/2006 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/15/2005 Female 134 lb 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Depression Hospitalization 7/4/2006 22 Female 8/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face 4/20/2006 52 Female 163 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 9/8/2006 Consumer Canada
Primary
Concomitant
Pneumonitis Hospitalization 1/1/2004 75 Male 9/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 5/31/2006 66 Female 8/29/2006 United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 1/1/2004 75 Male 9/12/2006 United Kingdom
Primary
Concomitant
Wegener's Granulomatosis Hospitalization 11/3/2005 Female 9/21/2006 Physician Germany
Primary
Secondary
Concomitant
Volvulus Other Serious 10/29/2005 Male 115 lb 9/27/2006 Consumer United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 9/29/2006 Physician United States
Primary
Secondary
Concomitant
Volvulus Other Serious 10/29/2005 Male 115 lb 10/4/2006 Consumer United Kingdom
Primary
Concomitant
Infection Hospitalization 9/6/2006 Female 10/13/2006 Consumer United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization Female 10/13/2006 Physician Australia
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 6/27/2006 Female 130 lb 10/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 6/27/2006 Female 130 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 11/7/2006 Consumer Canada
Primary
Concomitant
Dyspnoea Hospitalization Female 11/10/2006 Physician Australia
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/6/2006 Female 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 6/27/2006 Female 130 lb 11/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 9/24/2004 45 Female 168 lb 11/21/2006 France
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 11/1/2006 Male 12/6/2006 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious 7/1/2006 Female 12/13/2006 Physician Belgium
Primary
Secondary
Concomitant
Death Death 12/7/2006 70 Female 12/15/2006 Consumer Canada
Primary
Concomitant
Death Death 12/6/2006 70 Female 12/19/2006 Physician Canada
Primary
Concomitant
Mycosis Fungoides Other Serious 4/19/2006 Male 203 lb 12/22/2006 Physician United States
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 11/5/2006 66 Male 12/28/2006
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/15/2006 Male 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Scab Other Serious 7/14/2006 39 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death Female 128 lb 1/22/2007 France
Primary
Concomitant
Vasculitis Other Serious 1/1/2006 Male 163 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bunion Other Serious 11/1/2004 Female 134 lb 1/26/2007 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Death 8/18/2006 Male 115 lb 1/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wegener's Granulomatosis Other Serious 2/24/2005 Female 2/6/2007 Physician Germany
Primary
Secondary
Concomitant
Infection Hospitalization 9/6/2006 Female 2/8/2007 Consumer United Kingdom
Primary
Concomitant
Breast Mass Other Serious Female 148 lb 2/9/2007 Consumer Canada
Primary
Concomitant
Infarction Death 11/13/2006 Female 128 lb 2/16/2007 France
Primary
Concomitant
Nasopharyngitis Hospitalization 10/1/2006 Female 175 lb 2/23/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/5/2006 Female 178 lb 3/23/2007 Physician United States
Primary
Concomitant
Erythema Multiforme Other Serious 11/5/2000 70 Female 3/30/2007 Physician Spain
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/29/2006 Male 209 lb 3/30/2007 Physician Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 6/17/2006 Female 161 lb 4/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 3/12/2007 Female 117 lb 4/11/2007 Physician France
Primary
Concomitant
Uterine Polyp Other Serious 11/17/2005 Female 137 lb 4/12/2007 Physician Italy
Primary
Concomitant
Lung Disorder Hospitalization 4/1/2007 Female 4/19/2007 Physician Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/29/2006 Male 209 lb 4/20/2007 Physician Canada
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 3/12/2007 Female 117 lb 4/20/2007 Physician France
Primary
Concomitant
Pulmonary Fibrosis Life Threatening 6/1/2005 Male 187 lb 4/23/2007 Physician Canada
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization Female 140 lb 4/25/2007 Consumer Canada
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 4/12/2006 Male 161 lb 4/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 3/12/2007 Female 117 lb 4/27/2007 Physician France
Primary
Secondary
Concomitant
Tumour Invasion Life Threatening 3/12/2007 58 Female 4/23/2007 France
Primary
Secondary
Syncope Hospitalization 4/12/2006 Female 143 lb 5/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 125 lb 5/18/2007 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 11/16/2006 Female 123 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 8/15/2006 Male 223 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 4/12/2006 Female 143 lb 6/1/2007 Physician United Kingdom
Primary
Concomitant
Urinary Tract Disorder Hospitalization 3/1/2007 Male 230 lb 6/4/2007 Consumer Canada
Primary
Concomitant
Lung Disorder Hospitalization 4/1/2007 Female 6/5/2007 Physician Canada
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 5/15/2007 Female 108 lb 6/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/31/2006 Female 216 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lymphoma Required Intervention 5/25/2006 62 Female 167 lb 6/13/2007 Physician United States
Primary
Concomitant
Malaise Other Serious 9/1/2004 Female 238 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 3/1/2007 Female 183 lb 7/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cervical Dysplasia Other Serious 5/18/2006 Female 196 lb 7/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Metastases To Liver Other Serious 5/3/2007 Male 139 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 125 lb 7/26/2007 Physician Canada
Primary
Concomitant
Vasculitis Other Serious 1/1/2006 Male 163 lb 8/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 8/15/2007 Female 170 lb 9/6/2007 United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 5/15/2007 Female 108 lb 9/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Skin Test Positive Hospitalization 5/1/2006 Female 166 lb 9/14/2007 Physician United States
Primary
Concomitant
Tendon Injury Hospitalization Female 251 lb 9/24/2007 Canada
Primary
Concomitant
Arthropathy Hospitalization Female 126 lb 10/16/2007 Canada
Primary
Concomitant
Respiratory Disorder Female 10/25/2007 Consumer United States
Primary
Concomitant
Synovial Cyst Hospitalization Female 126 lb 11/2/2007 Canada
Primary
Concomitant
Liver Function Test Abnormal Other Serious 9/11/2007 72 Male 11/21/2007
Primary
Concomitant
Septic Shock Hospitalization 8/15/2007 Female 170 lb 11/29/2007 United Kingdom
Primary
Concomitant
Vaginitis Bacterial Other Serious 9/1/2006 Female 145 lb 12/6/2007 Canada
Primary
Concomitant
Injection Site Pain 6/1/2005 Female 123 lb 12/14/2007 Consumer United States
Primary
Concomitant
Salmonellosis 1/1/2006 Female 166 lb 12/14/2007 United States
Primary
Concomitant
Flatulence 10/24/2007 Male 148 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Pain 10/29/2007 Female 110 lb 12/15/2007 United States
Primary
Concomitant
Pain In Extremity Hospitalization 5/6/2007 55 Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 3/20/2007 Female 181 lb 12/21/2007 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 8/10/2007 Female 181 lb 12/28/2007 United Kingdom
Primary
Concomitant
Hodgkin's Disease Other Serious 6/21/2007 Male 248 lb 1/22/2008 Other Health Professional United States
Primary
Concomitant
Granuloma Other Serious 62 Female 1/25/2008 Norway
Primary
Concomitant
Infarction Hospitalization 11/13/2006 Female 128 lb 2/7/2008 France
Primary
Concomitant
Liver Function Test Abnormal Other Serious 9/11/2007 72 Male 2/13/2008
Primary
Concomitant
Cerebrovascular Accident Life Threatening 11/1/2007 Male 251 lb 2/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Life Threatening 11/7/2007 Male 251 lb 2/29/2008 United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization Male 168 lb 2/29/2008 Brazil
Primary
Concomitant
Vaginitis Bacterial Other Serious 9/1/2006 Female 145 lb 3/10/2008 Canada
Primary
Concomitant
Weight Increased Other Serious 12/5/2005 Female 133 lb 3/14/2008 United States
Primary
Concomitant
Staphylococcal Infection 8/16/2007 Female 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Accidental Exposure 12/20/2007 Female 120 lb 3/14/2008 Consumer United States
Primary
Concomitant
Dizziness Male 197 lb 3/15/2008 United States
Primary
Concomitant
Mobility Decreased 1/1/2008 Female 3/15/2008 United States
Primary
Concomitant
Injection Site Urticaria 1/31/2008 Female 124 lb 3/15/2008 United States
Primary
Concomitant
Accidental Exposure 2/15/2008 Female 190 lb 3/15/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 5/6/2007 Male 229 lb 3/25/2008 Physician United Kingdom
Primary
Concomitant
Uterine Leiomyoma Other Serious 3/1/2007 Female 152 lb 3/27/2008 United States
Primary
Concomitant
Urticaria Other Serious 1/1/2004 Female 4/3/2008 Physician United States
Primary
Concomitant
Peripheral Embolism Life Threatening 11/7/2007 Male 251 lb 4/4/2008 United Kingdom
Primary
Secondary
Concomitant
Uterine Polyp Other Serious 11/17/2005 Female 137 lb 4/4/2008 Physician Italy
Primary
Concomitant
Pain Hospitalization 10/2/2006 72 Male 4/8/2008 Other Health Professional United States
Primary
Concomitant
Sensory Disturbance Other Serious 2/1/2008 Male 4/24/2008 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 11/13/2006 Female 128 lb 4/25/2008 France
Primary
Concomitant
Colitis Hospitalization 4/15/2008 Female 198 lb 4/28/2008 United Kingdom
Primary
Concomitant
Death Death 7/30/2007 Female 5/20/2008 Canada
Primary
Concomitant
Retching Other Serious 4/16/2008 75 Male 112 lb 5/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral Embolism Hospitalization 5/16/2008 Male 210 lb 6/2/2008 United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 1/9/2008 Male 223 lb 6/4/2008 United Kingdom
Primary
Concomitant
Peripheral Embolism Hospitalization 5/16/2008 Male 210 lb 6/6/2008 United States
Primary
Concomitant
Hodgkin's Disease Stage Ii Other Serious 2/21/2008 Female 43 lb 6/5/2008 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Recurrent Other Serious 1/1/2005 Male 178 lb 6/12/2008 United States
Primary
Concomitant
Urinary Tract Infection 3/27/2007 Female 180 lb 6/12/2008 United States
Primary
Concomitant
Psoriatic Arthropathy 8/1/2006 32 Male 154 lb 6/13/2008 Physician United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 1/1/2005 Male 178 lb 6/18/2008 United States
Primary
Concomitant
Sudden Cardiac Death Death 8/7/2007 Male 6/27/2008 Germany
Primary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 6/30/2008 Germany
Primary
Secondary
Concomitant
Spinal Rod Insertion Hospitalization 4/23/2007 Female 140 lb 7/8/2008 Physician United States
Primary
Concomitant
Meniscus Lesion Other Serious 5/1/2008 Female 150 lb 7/8/2008 Consumer United States
Primary
Concomitant

Drug Data