Folic Acid combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypertrophy Other Serious 9/5/2005 Male 185 lb 1/27/2006 United States
Primary
Concomitant
Dizziness Postural Hospitalization 10/12/2005 Male 144 lb 10/13/2005 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 Female 2/28/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Contusion Hospitalization 3/17/2004 53 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2004 94 Female 103 lb 12/27/2005 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 10/26/2004 79 Male 175 lb 12/29/2005 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/2005 Male 200 lb 4/10/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 79 Female 4/12/2006 United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/17/2006 46 Female 4/13/2006 Other Health Professional Netherlands
Primary
Concomitant
Hypoglycaemia Hospitalization 3/17/2006 46 Female 4/17/2006 Other Health Professional Netherlands
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Photosensitivity Reaction Other Serious 9/21/2005 80 Male 5/8/2006 Pharmacist Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 2/20/2006 65 Male 5/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Macular Oedema 10/1/2005 74 Male 5/19/2006 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 9/5/2005 Male 185 lb 6/30/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 7/17/2006 Female 8/1/2006 Physician Australia
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 7/17/2006 Female 8/9/2006 Physician Australia
Primary
Concomitant
Fall Hospitalization Male 8/21/2006 Pharmacist United Kingdom
Primary
Concomitant
Haemoglobin Increased Other Serious 7/17/2006 Female 9/7/2006 Physician Australia
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 9/1/2006 63 Male 249 lb 9/6/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Life Threatening 9/26/2006 46 Male 142 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Death Death 10/17/2006 71 Male 11/17/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 5/1/2006 Female 12/20/2006 Pharmacist United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 9/21/2006 Male 150 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 8/23/2006 52 Male 329 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Delirium Hospitalization 10/22/2006 80 Male 1/27/2007 Physician Turkey
Primary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Delirium Other Serious 3/13/2007 70 Male 169 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 125 lb 5/18/2007 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/1/2007 Female 6/15/2007 Physician Norway
Primary
Concomitant
Pollakiuria 3/1/2007 85 Male 215 lb 4/5/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Chronic Death 5/30/2007 63 Female 95 lb 6/27/2007 Physician Thailand
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 125 lb 7/26/2007 Physician Canada
Primary
Concomitant
Oedema Peripheral Other Serious 5/15/2007 Male 8/20/2007 Physician United States
Primary
Secondary
Concomitant
Interacting
Headache Other Serious 6/1/2007 Female 73 lb 10/9/2007 Physician Denmark
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 11/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 7/15/2007 83 Male 11/21/2007 Physician United Kingdom
Primary
Concomitant
Skin Ulcer Death 10/19/2007 71 Male 154 lb 12/27/2007 Physician Greece
Primary
Concomitant
Abdominal Wall Abscess Hospitalization 3/29/2007 Female 134 lb 12/28/2007 United Kingdom
Primary
Concomitant
Cardiac Failure Death 12/7/2007 65 Male 1/10/2008 Other Health Professional Korea, Republic Of
Primary
Concomitant
Chest Pain Other Serious 9/15/2007 Female 73 lb 1/22/2008 United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 2/14/2007 Female 2/1/2008 Physician Norway
Primary
Concomitant
Death Death 8/14/2007 68 Male 112 lb 2/25/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased 1/1/2007 61 Male 175 lb 12/5/2007 Physician United States
Primary
Concomitant
Nutritional Condition Abnormal Other Serious 3/1/2008 65 Male 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 1/18/2008 80 Male 157 lb 3/31/2008 Greece
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 5/11/2004 Male 198 lb 4/16/2008 Consumer United States
Primary
Concomitant
Parkinson's Disease Other Serious Male 230 lb 4/21/2008 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 1/18/2008 80 Male 157 lb 4/28/2008 Greece
Primary
Concomitant
Tremor Hospitalization 4/25/2008 Female 113 lb 4/28/2008 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 2/1/2008 Female 137 lb 4/30/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 2/8/2008 Male 110 lb 5/23/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Tremor Hospitalization 4/20/2008 Female 112 lb 6/9/2008 Pharmacist United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 6/3/2008 66 Male 163 lb 6/12/2008 Greece
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Neutropenic Sepsis Death 71 Female 7/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Fluctuation 81 Female 172 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/1998 Male 8/15/2008 United States
Primary
Secondary
Concomitant
Swelling Face 5/12/2008 Female 249 lb 8/27/2008 Other Health Professional United States
Primary
Concomitant
Headache 7/7/2008 Female 8/27/2008 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 6/2/2008 55 Male 194 lb 7/30/2008 Pharmacist United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 5/26/2008 Female 99 lb 9/3/2008 United Kingdom
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 6/3/2008 66 Male 163 lb 9/9/2008 Greece
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 10/30/2008 Consumer Spain
Primary
Concomitant
Medication Residue Female 11/17/2008 Physician Puerto Rico
Primary
Concomitant
Product Quality Issue Other Serious 7/1/2007 56 Male 190 lb 11/25/2008 Consumer United States
Primary
Concomitant
Pneumonia 1/1/2006 Female 125 lb 12/12/2008 United States
Primary
Concomitant
Product Quality Issue 9/17/2008 Male 225 lb 12/12/2008 United States
Primary
Concomitant
Stent Placement Other Serious 8/1/2006 Male 12/17/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 63 Male 12/15/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 12/23/2008 Physician Spain
Primary
Concomitant
Renal Failure Other Serious 1/1/1998 78 Male 137 lb 1/14/2009 Consumer United States
Primary
Secondary
Concomitant
Stent Placement Hospitalization 4/1/2008 49 Female 255 lb 1/21/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 1/28/2009 Physician Spain
Primary
Concomitant
Unevaluable Event Hospitalization 9/1/2004 Female 179 lb 2/13/2009 Physician United Kingdom
Primary
Concomitant
Serratia Infection Hospitalization 9/1/2004 Female 179 lb 2/23/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 2/18/2009 67 Female 187 lb 3/9/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 2/18/2009 67 Female 188 lb 3/4/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 2/18/2009 67 Female 188 lb 3/4/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 2/18/2009 67 Female 185 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Bacterial Infection Hospitalization 3/6/2009 Female 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Bacterial Infection Hospitalization 3/6/2009 Female 4/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face 1/1/2007 5/4/2009 United States
Primary
Concomitant
Haemoglobin Decreased 3/23/2009 Female 5/4/2009 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 3/6/2009 Female 5/7/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Death 2/18/2009 Female 183 lb 5/14/2009 United Kingdom
Primary
Concomitant
Swelling Face 1/1/2007 Female 120 lb 5/22/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 11/1/2008 51 Male 200 lb 5/21/2009 Consumer United States
Primary
Concomitant
Rash 3/2/2009 62 Male 130 lb 5/15/2009 Consumer United States
Primary
Concomitant
Sepsis Death 2/18/2009 Female 183 lb 6/3/2009 United Kingdom
Primary
Concomitant
Vomiting Other Serious 4/1/2008 81 Female 7/8/2009 Physician Spain
Primary
Concomitant
Vomiting Hospitalization 47 Female 163 lb 7/7/2009 Lawyer United States
Primary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2008 81 Female 7/24/2009 Physician Spain
Primary
Concomitant
Pulmonary Embolism Other Serious 7/15/2009 Male 163 lb 7/28/2009 Physician Greece
Primary
Secondary
Concomitant
Hand Deformity Other Serious 4/1/2009 Male 7/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hand Deformity Other Serious 4/1/2009 76 Male 8/6/2009 United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 6/10/2009 59 Male 8/5/2009 Other Health Professional Denmark
Primary
Concomitant
Sepsis Death 2/18/2009 Female 183 lb 8/21/2009 United Kingdom
Primary
Concomitant
Paraesthesia Female 8/21/2009 United States
Primary
Concomitant
Headache 8/19/2008 Female 8/21/2009 United States
Primary
Concomitant
Sepsis Death 2/18/2009 Female 183 lb 8/24/2009 United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 12/1/2008 79 Female 9/14/2009 Other Health Professional Norway
Primary
Concomitant
Retroperitoneal Haematoma Life Threatening 85 Female 9/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unevaluable Event Disability 7/1/2009 75 Female 142 lb 9/8/2009 Physician United States
Primary
Concomitant
Retroperitoneal Haematoma Life Threatening 85 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculous Pleurisy Life Threatening 9/9/2007 Male 143 lb 9/22/2009 Physician Thailand
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/27/2008 93 Female 9/24/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 7/7/2009 Male 163 lb 10/6/2009 Physician Greece
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 10/8/2009 Physician Netherlands
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/4/2009 84 Female 10/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/4/2009 84 Female 10/13/2009 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/4/2009 84 Female 10/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/4/2009 84 Female 10/21/2009
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/4/2009 84 Female 10/23/2009 United Kingdom
Primary
Concomitant
Tuberculous Pleurisy Life Threatening 9/9/2007 Male 143 lb 11/3/2009 Physician Thailand
Primary
Secondary
Concomitant
Graft Thrombosis Hospitalization 10/19/2009 Female 133 lb 11/9/2009 Physician Greece
Primary
Concomitant
Dyspnoea Other Serious 6/10/2009 59 Male 11/4/2009 Other Health Professional Denmark
Primary
Concomitant
Vascular Graft Thrombosis Hospitalization 10/19/2009 Female 133 lb 11/23/2009 Physician Greece
Primary
Concomitant
Visual Impairment Other Serious 65 Male 11/17/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/27/2008 93 Female 11/17/2009 United States
Primary
Concomitant
Head Injury Hospitalization 10/25/2009 92 Male 12/1/2009 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Female 141 lb 12/4/2009 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Female 141 lb 12/8/2009 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 10/20/2009 72 Male 12/1/2009 Consumer Brazil
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/9/2009 Male 158 lb 12/17/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2007 75 Female 130 lb 12/21/2009 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/9/2009 Male 160 lb 12/23/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 12/28/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 1/5/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 1/7/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Hypersensitivity Hospitalization 8/5/2009 67 Male 176 lb 12/18/2009 Other Health Professional United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 5/22/2008 68 Female 1/14/2010 Physician Germany
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 162 lb 1/20/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Sepsis Life Threatening 5/12/2008 71 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 65 Male 1/12/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 11/1/2008 51 Male 210 lb 1/20/2010 Consumer United States
Primary
Concomitant
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant
Death Death 12/23/2009 Male 168 lb 1/29/2010 Physician Spain
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 161 lb 2/8/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 161 lb 2/8/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Reflux Gastritis Other Serious 9/8/2006 Male 290 lb 2/9/2010 Physician United States
Primary
Concomitant

Drug Data