Fluorouracil combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Loss Other Serious 4/1/2005 68 Female 1/4/2006 Physician Italy
Primary
Concomitant
Renal Impairment Other Serious 3/25/2004 76 Male 1/24/2006 Physician Belgium
Primary
Concomitant
Toothache Other Serious 8/26/2005 56 Female 1/24/2006 Physician Belgium
Primary
Secondary
Concomitant
Wound Other Serious Male 2/6/2006 United States
Primary
Concomitant
Pain In Jaw Other Serious 7/15/2004 53 Female 2/15/2006 United States
Primary
Concomitant
Sequestrectomy Other Serious 1/1/2005 74 Male 161 lb 2/18/2006 Physician Germany
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 2/24/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/17/2006 Physician France
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 9/30/2005 61 Male 3/6/2006 Consumer Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 6/1/2005 59 Female 3/23/2006 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/30/2005 59 Female 3/28/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 10/20/2004 54 Female 3/29/2006 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 6/30/2005 59 Female 4/4/2006 United States
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 4/10/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/19/2003 54 Female 4/20/2006 Other Health Professional United States
Primary
Concomitant
Pain In Jaw Disability 2/7/2006 64 Female 4/30/2006 Italy
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/5/2006 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/6/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2005 65 Female 115 lb 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Toothache Other Serious 63 Female 132 lb 5/24/2006 Portugal
Primary
Concomitant
Swelling Other Serious 4/13/2006 51 Female 5/24/2006 Physician Portugal
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/31/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 6/30/2005 59 Female 6/4/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Death 5/3/2006 62 Female 95 lb 6/7/2006 Physician Japan
Primary
Concomitant
Toothache Other Serious 8/1/2005 63 Female 132 lb 6/8/2006 Portugal
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 6/16/2006 Other Health Professional Turkey
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 6/20/2006 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/29/2005 58 Male 157 lb 6/21/2006 Physician France
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 2/21/2006 78 Female 6/26/2006 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 2/1/2004 62 Female 121 lb 7/8/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 5/3/2006 62 Female 95 lb 7/10/2006 Physician Japan
Primary
Concomitant
Osteomyelitis Hospitalization 2/1/2005 58 Female 7/21/2006 Italy
Primary
Concomitant
Osteomyelitis Hospitalization 9/20/2004 66 Female 7/21/2006 Italy
Primary
Concomitant
Osteomyelitis Hospitalization 1/16/2006 62 Female 7/21/2006 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 2/24/2005 85 Female 7/26/2006 Physician United States
Primary
Concomitant
Swelling Other Serious 7/1/2006 56 Male 7/31/2006 United States
Primary
Concomitant
Pain In Jaw Other Serious 2/21/2006 78 Female 8/4/2006 Physician United States
Primary
Concomitant
Tooth Loss Other Serious 8/23/2005 78 Female 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Renal Vasculitis Hospitalization 6/10/2006 58 Female 183 lb 8/9/2006 Other Health Professional France
Primary
Secondary
Tooth Extraction Other Serious 2/24/2005 85 Female 8/14/2006 Physician United States
Primary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 8/19/2006 France
Primary
Secondary
Swelling Other Serious 6/30/2006 56 Male 8/23/2006 Physician United States
Primary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 8/19/2006 France
Primary
Secondary
Tooth Loss Other Serious 1/1/2006 65 Female 9/12/2006 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/23/2006 48 Male 9/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 8/8/2006 France
Primary
Secondary
Concomitant
Toothache Other Serious 8/26/2005 56 Female 9/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/25/2004 76 Male 9/26/2006 Physician Belgium
Primary
Concomitant
Tooth Loss Other Serious 1/1/2006 65 Female 10/4/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2006 65 Female 10/25/2006 Physician Japan
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 11/17/2006 France
Primary
Secondary
Wheezing Other Serious 3/25/1997 70 Female 126 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 52 Female 12/18/2006 United States
Primary
Concomitant
Osteonecrosis Disability 6/1/2006 57 Female 12/20/2006 Physician Belgium
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/2004 54 Female 140 lb 1/5/2007 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/2004 54 Female 140 lb 1/5/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/24/2005 70 Male 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 1/18/2007 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/20/2004 54 Female 140 lb 1/19/2007 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 1/23/2007 United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 6/15/2004 52 Female 1/26/2007 France
Primary
Concomitant
Vision Blurred Other Serious 10/18/2004 54 Female 140 lb 1/30/2007 United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 1/1/2007 65 Female 1/31/2007 Physician Japan
Primary
Secondary
Wheezing Other Serious 12/28/2001 62 Female 140 lb 2/1/2007 United States
Primary
Secondary
Concomitant
Renal Vasculitis Hospitalization 6/10/2006 58 Female 183 lb 2/2/2007 Other Health Professional France
Primary
Secondary
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/7/2007 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 10/1/2001 62 Female 140 lb 2/10/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 2/10/2007 Lawyer United States
Primary
Concomitant
Trismus Other Serious 4/13/2000 47 Female 2/14/2007 Physician United States
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 2/15/2007 France
Primary
Secondary
Uterine Neoplasm Hospitalization 12/1/2006 72 Female 115 lb 2/15/2007 Physician Japan
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 1/1/2007 65 Female 2/19/2007 Consumer United States
Primary
Secondary
Liver Disorder Hospitalization 1/1/2007 65 Female 2/21/2007 Physician Japan
Primary
Secondary
Wound Drainage Other Serious 4/13/2000 47 Female 179 lb 2/21/2007 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/1/2004 54 Female 140 lb 2/22/2007 United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 12/1/2006 Female 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 12/1/2006 Female 3/7/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 52 Female 3/8/2007 United States
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 3/10/2007 United States
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 12/1/2006 65 Female 3/12/2007 Consumer United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 3/12/2007 Lawyer United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 3/17/2007 Physician United States
Primary
Secondary
Concomitant
Hypocalcaemia Life Threatening 2/28/2007 Female 3/19/2007 Germany
Primary
Secondary
Wound Drainage Other Serious 4/13/2000 47 Female 207 lb 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 12/1/2006 65 Female 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 2/28/2007 Female 3/26/2007 Germany
Primary
Secondary
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 3/28/2007 Lawyer United States
Primary
Concomitant
Renal Vasculitis Hospitalization 6/10/2006 58 Female 3/2/2007 France
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/13/2000 47 Female 207 lb 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/16/2006 Female 134 lb 4/16/2007 Physician Japan
Primary
Secondary
Concomitant
Hypocalcaemia Life Threatening 2/28/2007 65 Female 4/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/1/2004 78 Female 4/24/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Wheezing Other Serious 12/16/2006 65 Female 4/25/2007 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/8/2007 42 Female 121 lb 5/30/2007 Physician France
Primary
Concomitant
Vision Blurred Other Serious 10/1/2004 54 Female 140 lb 6/2/2007 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/13/2000 47 Female 207 lb 6/8/2007 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 7/12/2007 Lawyer United States
Primary
Concomitant
Tetany Other Serious 2/28/2007 65 Female 8/14/2007 Consumer Germany
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 2/28/2007 Female 8/17/2007 Germany
Primary
Secondary
Tooth Extraction Other Serious 3/23/2004 53 Female 8/18/2007 Physician Belgium
Primary
Concomitant
Tooth Extraction Other Serious 3/23/2004 53 Female 8/18/2007 Physician Belgium
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Trousseau's Syndrome Hospitalization 2/28/2007 Female 8/23/2007 Germany
Primary
Secondary
Tetany Other Serious 2/28/2007 65 Female 8/29/2007 Consumer Germany
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2004 53 Female 9/29/2007 France
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 9/13/2007 Male 203 lb 10/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Metrorrhagia 7/27/2007 68 Female 10/31/2007 Other Health Professional Italy
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 9/13/2007 Male 203 lb 11/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/1/2007 58 Female 139 lb 11/23/2007 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 6/22/2005 Male 165 lb 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 8/10/2007 50 Female 128 lb 11/29/2007 Physician Germany
Primary
Secondary
Concomitant
Pain In Jaw Hospitalization 1/10/2007 68 Female 12/12/2007 France
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 1/7/2008 Lawyer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 81 Female 1/15/2008 United States
Primary
Secondary
Concomitant
Primary Sequestrum Other Serious 4/1/2002 50 Female 168 lb 1/18/2008 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 81 Female 192 lb 1/19/2008 United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 1/25/2008 Consumer United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 2/7/2008 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2006 56 Male 240 lb 2/14/2008 Physician Germany
Primary
Concomitant
Wound Dehiscence Other Serious 5/18/2005 55 Female 176 lb 3/4/2008 Physician Denmark
Primary
Concomitant
Tooth Extraction Other Serious 7/5/2007 60 Female 165 lb 3/11/2008 Denmark
Primary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 3/17/2008 Physician Denmark
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 3/18/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 56 Female 119 lb 3/19/2008 Physician Japan
Primary
Secondary
Wound Drainage Other Serious 4/13/2000 47 Female 207 lb 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/9/2001 69 Female 169 lb 3/27/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2003 52 Female 190 lb 3/28/2008 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 2/22/2001 42 Female 207 lb 4/3/2008 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 4/18/2008 Other Health Professional Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/12/2007 56 Female 119 lb 4/21/2008 Physician Japan
Primary
Secondary
Gastrointestinal Haemorrhage Hospitalization 5/1/2008 Female 150 lb 5/6/2008 United States
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 5/20/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 5/29/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/9/2007 Female 126 lb 7/31/2008 Physician Denmark
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 6/29/2005 Male 165 lb 8/5/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 4/1/2002 8/20/2008 United States
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 8/22/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Disability 8/11/2008 Female 9/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Strabismus Other Serious 9/4/2008 80 Female 10/1/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious Female 10/10/2008 United States
Primary
Concomitant
Tooth Extraction Other Serious 11/1/2001 Female 110 lb 11/5/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/1/2001 Female 110 lb 11/5/2008 Physician Japan
Primary
Secondary
Concomitant

Drug Data