Fluorouracil combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 1/13/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/1/2002 79 Female 176 lb 1/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Appendicitis Hospitalization 9/8/2005 68 Male 211 lb 2/1/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Type Iv Hypersensitivity Reaction Other Serious 7/10/2005 43 Female 191 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/4/2005 49 Female 3/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 5/1/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased 9/21/2005 67 Male 3/1/2006 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/1/2005 80 Male 210 lb 2/24/2006 United States
Primary
Secondary
Concomitant
Swelling Other Serious 4/13/2006 51 Female 5/24/2006 Physician Portugal
Primary
Concomitant
Laryngospasm Life Threatening 5/23/2006 Female 6/14/2006 Other Health Professional Australia
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 6/21/2006 Consumer United States
Primary
Secondary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 7/26/2006 Consumer United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 7/21/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 7/10/2006 Male 153 lb 8/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 7/17/2006 Male 153 lb 8/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 5/14/2006 78 Male 7/31/2006 Physician United States
Primary
Secondary
Concomitant
Infusion Related Reaction Hospitalization 5/10/2006 79 Female 8/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Hospitalization 7/17/2006 Male 153 lb 8/25/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 7/8/2006 Male 153 lb 9/7/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/8/2006 Male 153 lb 9/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Vena Cava Thrombosis Life Threatening 6/20/2005 43 Male 187 lb 9/5/2006 Physician Brazil
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 9/13/2006 Consumer United States
Primary
Secondary
Concomitant
Rash Disability 5/10/2006 59 Female 128 lb 9/14/2006 Consumer United States
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 9/7/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 8/6/2006 42 Male 9/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 8/6/2006 42 Male 9/22/2006 Japan
Primary
Secondary
Small Intestinal Obstruction Hospitalization 6/25/2005 59 Male 256 lb 9/22/2006 Physician United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 6/12/2006 39 Male 10/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 10/10/2006 Consumer United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 8/30/2006 Female 117 lb 10/16/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 10/5/2006 Belgium
Primary
Secondary
Concomitant
Pain Hospitalization 8/25/2006 46 Unknown 10/13/2006 Physician United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 8/7/2006 42 Male 10/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/19/2005 65 Male 10/25/2006 Physician Ireland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious Male 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Hospitalization 8/19/2005 Male 12/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 10/17/2006 72 Male 12/11/2006 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/20/2004 54 Female 140 lb 1/19/2007 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/18/2004 54 Female 140 lb 1/30/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/13/2006 63 Male 2/5/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/8/2007 74 Male 1/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/14/2005 Male 209 lb 2/16/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/1/2004 54 Female 140 lb 2/22/2007 United States
Primary
Secondary
Concomitant
Hyperthermia Hospitalization 10/26/2005 40 Male 115 lb 3/1/2007 Consumer United States
Primary
Secondary
Concomitant
Hyperthermia Hospitalization 10/26/2005 40 Male 115 lb 3/12/2007 Consumer United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 10/26/2004 75 Male 180 lb 3/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 3/16/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/2/2005 72 Female 3/14/2007 Belgium
Primary
Secondary
Concomitant
Uterine Haemorrhage Hospitalization 2/26/2007 Female 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 2/23/2007 69 Male 4/19/2007 Consumer United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 10/1/2004 54 Female 140 lb 6/2/2007 United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/24/2007 77 Male 236 lb 6/5/2007 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 6/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 6/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 8/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 8/13/2007 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/4/2007 Male 8/23/2007 Physician Australia
Primary
Concomitant
Stomatitis Hospitalization 7/23/2007 82 Male 8/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/23/2007 82 Male 9/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 75 Male 10/5/2007 United States
Primary
Concomitant
Sepsis Hospitalization 7/23/2007 82 Male 10/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haematemesis Hospitalization 9/5/2007 69 10/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/20/2007 56 Female 10/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/2/2007 11/19/2007 Australia
Primary
Secondary
Concomitant
Weight Decreased Death 1/1/2007 75 Male 11/14/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/2/2007 Female 12/5/2007 Australia
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Anastomotic Complication Life Threatening 12/5/2007 Male 216 lb 12/17/2007 Physician United States
Primary
Secondary
Concomitant
Anastomotic Complication Life Threatening 12/5/2007 Male 216 lb 12/28/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 1/2/2008 Physician United States
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 12/27/2007 74 Male 1/10/2008 Consumer United Kingdom
Primary
Concomitant
Leukocytosis Life Threatening 12/5/2007 Male 214 lb 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/24/2005 Male 177 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 12/5/2007 Male 214 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 4/24/2007 67 Male 1/31/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/24/2005 Male 177 lb 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 2/11/2008 Physician Australia
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 12/27/2007 74 Male 2/21/2008 Consumer United Kingdom
Primary
Concomitant
Epistaxis Hospitalization 9/30/2007 84 Male 2/20/2008 Pharmacist United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 59 Female 3/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 3/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 3/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/13/2006 63 Male 262 lb 3/21/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Life Threatening 12/5/2007 Male 214 lb 4/8/2008 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/9/2008 Male 4/29/2008 Consumer United Kingdom
Primary
Concomitant
Catheter Related Complication Life Threatening 9/18/2007 68 Male 193 lb 2/28/2008 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 4/9/2008 Male 6/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/5/2008 Male 6/9/2008 Physician Italy
Primary
Secondary
Concomitant
Drug Interaction Other Serious 59 Male 7/1/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/8/2007 61 Female 7/2/2008 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Hospitalization 3/13/2008 54 Male 4/14/2008 Pharmacist United States
Primary
Secondary
Oesophagitis Life Threatening 9/5/2007 69 7/30/2008 Consumer Ireland
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/21/2007 Male 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Life Threatening 9/5/2007 69 8/22/2008 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/2/2008 Male 115 lb 8/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/14/2008 71 Male 9/18/2008 Physician United Kingdom
Primary
Secondary
Sepsis Hospitalization 6/21/2007 Male 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 12/27/2007 74 Male 10/14/2008 Consumer United Kingdom
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 12/27/2007 74 Male 130 lb 10/15/2008 Physician Japan
Primary
Secondary
Drug Hypersensitivity Life Threatening 11/7/2005 Female 108 lb 10/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/11/2008 Male 106 lb 10/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/2/2008 Male 115 lb 11/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/13/2006 63 Male 262 lb 12/5/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/13/2006 63 Male 262 lb 12/23/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 10/4/2005 Female 2/13/2009 Physician Italy
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/2/2009 Female 122 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Carcinoembryonic Antigen Increased Other Serious 2/9/2009 67 Male 3/5/2009 Consumer Canada
Primary
Concomitant
Gastrointestinal Perforation Life Threatening 8/27/2008 Female 100 lb 4/7/2009 Physician Japan
Primary
Secondary
Concomitant
Carcinoembryonic Antigen Increased Other Serious 2/9/2009 67 Male 4/20/2009 Physician Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/5/2009 Ireland
Primary
Concomitant
Carcinoembryonic Antigen Increased Other Serious 2/9/2009 67 Male 7/24/2009 Physician Canada
Primary
Concomitant
Mental Disorder Hospitalization 2/12/2008 Female 8/13/2009 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 10/26/2004 75 Male 180 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2004 Female 140 lb 10/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Life Threatening 1/15/2009 Male 11/20/2009 Physician Denmark
Primary
Concomitant
Aortic Dissection Rupture Death 2/17/2009 Male 119 lb 12/15/2009 Pharmacist Japan
Primary
Concomitant
Venous Thrombosis Other Serious 10/20/2009 71 Female 126 lb 12/16/2009 Physician Germany
Primary
Concomitant
Convulsion Hospitalization 10/18/2009 Male 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Life Threatening 9/5/2007 69 12/24/2009 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/13/2005 Male 172 lb 12/28/2009 Physician France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/18/2009 58 Male 1/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 11/26/2009 74 Male 170 lb 2/26/2010 United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/28/2009 74 Male 3/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mitral Valve Incompetence Other Serious 55 Female 3/9/2010 Other Health Professional Brazil
Primary
Concomitant
Vitamin B12 Increased Other Serious 74 Male 3/6/2010 United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/1/2009 74 Male 170 lb 3/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraproteinaemia Other Serious 8/28/2009 74 Male 3/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/28/2009 74 Male 3/15/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 10/1/2004 Female 140 lb 3/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraproteinaemia Other Serious 8/1/2009 74 Male 170 lb 3/15/2010 United Kingdom
Primary
Secondary
Concomitant
Paraproteinaemia Other Serious 74 Male 3/20/2010 United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2002 Female 3/26/2010 United States
Primary
Concomitant
Pyrexia Hospitalization 5/31/2008 54 Male 202 lb 3/29/2010 Physician South Africa
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2002 63 Female 4/7/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2004 54 Female 140 lb 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2002 63 Female 4/16/2010 United States
Primary
Concomitant
Pyrexia Hospitalization 5/31/2008 54 Male 202 lb 4/27/2010 Physician South Africa
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 10/20/2009 71 Female 126 lb 4/29/2010 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 10/1/2004 54 Female 140 lb 4/30/2010 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 10/4/2005 Female 5/12/2010 Physician United States
Primary
Secondary
Pyrexia Life Threatening 1/6/2010 69 Female 203 lb 5/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2004 54 Female 140 lb 6/4/2010 United States
Primary
Secondary
Concomitant
Tongue Haematoma Other Serious 1/1/2009 60 Male 7/29/2010 Consumer France
Primary
Secondary
Weight Decreased Other Serious 71 Male 265 lb 9/17/2010 Consumer United States
Primary
Concomitant
Drug Hypersensitivity Other Serious 4/6/2010 59 Male 8/10/2010 Other Health Professional United States
Primary
Concomitant
Palpitations Hospitalization 12/10/2010 56 Female 227 lb 1/12/2011 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Life Threatening 8/25/2010 47 Male 183 lb 3/21/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data