Fluorouracil combined with Trastuzumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/25/2002 66 Female 5/21/2007 Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/25/2002 66 Female 5/25/2007 Japan
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 10/21/2007 Female 154 lb 12/11/2007 Physician United Kingdom
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Hepatocellular Injury Other Serious 31 Female 1/26/2008 Consumer United Kingdom
Primary
Concomitant
Liver Injury Other Serious 31 Female 3/12/2008 Other Health Professional Spain
Primary
Secondary
Liver Injury Other Serious 31 Female 3/13/2008 Other Health Professional Spain
Primary
Secondary
Rash Other Serious 41 Female 4/15/2008 Other Health Professional Japan
Primary
Secondary
Pain Other Serious 41 Female 4/18/2008 Other Health Professional Japan
Primary
Secondary
Pain 41 Female 4/23/2008 Other Health Professional United States
Primary
Secondary
Pain Other Serious 41 Female 4/25/2008 Consumer United States
Primary
Secondary
Pain 41 Female 4/28/2008 Other Health Professional United States
Primary
Secondary
Hepatotoxicity Other Serious 31 Female 5/15/2008
Primary
Secondary
Weight Increased Other Serious Female 8/29/2008 Consumer France
Primary
Concomitant
Angina Pectoris Hospitalization 9/20/2008 Female 10/2/2008 Physician United Kingdom
Primary
Secondary
Angina Pectoris Hospitalization 9/19/2008 Female 10/17/2008 Physician United Kingdom
Primary
Secondary
Neutropenia Hospitalization 9/19/2008 Female 12/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 9/19/2008 Female 12/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 9/19/2008 Female 3/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization Female 4/23/2009 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/19/2009 28 Female 294 lb 5/12/2009 Physician United States
Primary
Secondary
Hepatotoxicity Other Serious 31 Female 6/22/2009 Other Health Professional Spain
Primary
Concomitant
Wheezing Other Serious 3/25/1997 Female 126 lb 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 31 Female 7/1/2009 Other Health Professional Spain
Primary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 56 Female 7/8/2009 Other Health Professional Japan
Primary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 7/10/2009 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/19/2009 28 Female 294 lb 7/14/2009 Physician United States
Primary
Secondary
Pulmonary Oedema Hospitalization 6/1/2006 56 Female 7/30/2009 Other Health Professional Japan
Primary
Concomitant
Enteritis Hospitalization 8/14/2009 Female 8/26/2009 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 7/20/2009 Female 137 lb 9/9/2009 Physician Japan
Primary
Secondary
Concomitant
Enteritis Hospitalization 8/14/2009 Female 9/10/2009 Consumer United Kingdom
Primary
Secondary
Abortion Spontaneous Other Serious 36 Female 9/15/2009 Consumer United Kingdom
Primary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 10/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 10/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/13/2009 Female 150 lb 10/15/2009 Physician Germany
Primary
Secondary
Oesophagitis Hospitalization 8/14/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Other Serious 7/25/2008 55 Female 10/29/2009 Other Health Professional France
Primary
Secondary
Oesophagitis Hospitalization 8/14/2009 Female 11/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 11/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/8/2009 Female 11/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/8/2009 Female 11/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Other Serious 7/25/2008 55 Female 11/30/2009 Other Health Professional France
Primary
Secondary
Pneumonia Hospitalization 11/24/2009 Female 101 lb 12/9/2009 Physician Belgium
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 111 lb 12/10/2009 Physician Thailand
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/6/2009 40 Female 193 lb 12/16/2009 Physician United States
Primary
Secondary
Oesophagitis Hospitalization 8/14/2009 Female 111 lb 12/21/2009 Physician Thailand
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/15/2009 37 Female 135 lb 12/21/2009 Physician United States
Primary
Secondary
Dyspnoea Hospitalization 2/13/2006 Female 234 lb 12/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/24/2009 Female 101 lb 1/15/2010 Physician Belgium
Primary
Secondary
Concomitant
Diarrhoea Other Serious 12/29/2009 Female 132 lb 1/15/2010 Physician France
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 111 lb 1/21/2010 Physician Thailand
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/14/2010 34 Female 251 lb 1/25/2010 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 4/1/2008 58 Female 1/29/2010 Other Health Professional France
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 1/30/2010 Female 161 lb 2/16/2010 Physician France
Primary
Secondary
Myocardial Ischaemia Hospitalization 11/1/2009 Female 141 lb 2/26/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 11/1/2009 Female 3/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 11/1/2009 Female 141 lb 3/8/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 11/24/2009 Female 101 lb 3/10/2010 Physician Belgium
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 11/1/2009 Female 141 lb 3/11/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 11/1/2009 Female 3/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/18/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/24/2003 Female 159 lb 3/19/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Withdrawal Syndrome Life Threatening 33 Female 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/25/2010 United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 11/1/2009 Female 141 lb 3/26/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/6/2010 Female 3/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 12/14/2009 37 Female 134 lb 4/1/2010 Physician United States
Primary
Secondary
Pulmonary Embolism Hospitalization 4/16/2010 58 Female 132 lb 4/29/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/16/2010 58 Female 132 lb 4/30/2010 Physician Germany
Primary
Secondary
Concomitant
Alopecia Disability 1/1/2008 67 Female 5/6/2010 Other Health Professional France
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Alopecia Disability 1/1/2008 39 Female 5/11/2010 Physician France
Primary
Secondary
Concomitant
Syncope Hospitalization 9/13/2005 46 Female 161 lb 5/11/2010 Physician Italy
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 66 Female 111 lb 5/12/2010 Physician Thailand
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9/27/2005 46 Female 161 lb 5/13/2010 Physician Italy
Primary
Secondary
Phrenic Nerve Paralysis Other Serious 58 Female 5/14/2010 Physician Lebanon
Primary
Secondary
Alopecia Disability 1/1/2008 39 Female 5/25/2010 Physician France
Primary
Secondary
Concomitant
Enteritis Hospitalization 4/11/2007 45 Female 137 lb 5/26/2010 Physician Germany
Primary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 5/28/2010 United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/14/2010 34 Female 251 lb 6/8/2010 Physician United States
Primary
Secondary
Tumour Invasion Other Serious 11/30/2005 48 Female 6/9/2010 United States
Primary
Concomitant
Syncope Hospitalization 9/13/2005 46 Female 161 lb 6/12/2010 Physician Italy
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 6/15/2010 United States
Primary
Concomitant
Disease Recurrence Death 4/21/2009 37 Female 172 lb 6/23/2010 Other Health Professional Germany
Primary
Concomitant
Pyrexia Hospitalization 1/13/2009 66 Female 150 lb 6/23/2010 Physician Germany
Primary
Secondary
Diarrhoea Hospitalization 12/6/2009 40 Female 193 lb 7/6/2010 Physician United States
Primary
Secondary
Tumour Invasion Other Serious 11/30/2005 48 Female 7/8/2010 United States
Primary
Concomitant
Metrorrhagia Hospitalization 6/1/2010 35 Female 139 lb 7/14/2010 Physician Brazil
Primary
Secondary
Concomitant
Skin Nodule Hospitalization 6/14/2010 63 Female 159 lb 7/14/2010 Physician Brazil
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/1/2006 37 Female 119 lb 7/28/2010 Physician Canada
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 12/29/2009 25 Female 132 lb 7/26/2010 Physician France
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 9/18/2009 63 Female 174 lb 7/29/2010 Physician Italy
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 11/24/2009 42 Female 101 lb 7/30/2010 Physician Belgium
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 12/29/2009 25 Female 132 lb 8/2/2010 Physician France
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 11/24/2009 42 Female 8/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 8/12/2010 United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 7/20/2010 67 Female 143 lb 8/13/2010 Physician Switzerland
Primary
Secondary
Wheezing Other Serious 2/1/1998 66 Female 126 lb 8/20/2010 United States
Primary
Secondary
Concomitant
Skin Nodule Other Serious 6/14/2010 63 Female 159 lb 8/26/2010 Physician Brazil
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 8/27/2010 United States
Primary
Concomitant
Metastases To Liver Other Serious 9/18/2009 63 Female 174 lb 9/1/2010 Physician Italy
Primary
Secondary
Concomitant
Cardiotoxicity Other Serious 7/20/2010 53 Male 9/9/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 9/10/2010 Other Health Professional Greece
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 116 lb 9/27/2010 United States
Primary
Concomitant
Clostridial Infection Hospitalization 8/1/2010 65 Female 97 lb 10/5/2010 Physician Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/20/2010 65 Female 97 lb 10/13/2010 Physician Canada
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 10/7/2010 60 Male 205 lb 10/19/2010 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 10/1/2010 66 Female 172 lb 10/20/2010 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 10/1/2010 66 Female 172 lb 10/21/2010 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Death 10/15/2010 77 Female 123 lb 10/25/2010 Physician Brazil
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/15/2010 77 Female 123 lb 10/28/2010 Physician Brazil
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/5/2009 46 Female 11/2/2010 Physician United Kingdom
Primary
Secondary
Gastric Perforation Hospitalization 3/15/2010 74 Female 154 lb 11/3/2010 Physician Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/7/2010 60 Male 205 lb 11/4/2010 Physician Germany
Primary
Secondary
Malignant Neoplasm Progression Death Female 11/5/2010 Other Health Professional Spain
Primary
Secondary
Thrombocytopenia Hospitalization 10/15/2010 77 Female 123 lb 11/16/2010 Physician Brazil
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 11/24/2009 42 Female 101 lb 11/16/2010 Physician Belgium
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 11/24/2009 42 Female 11/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Other Serious 3/28/2010 81 Female 163 lb 11/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 12/14/2009 37 Female 134 lb 11/18/2010 Physician United States
Primary
Secondary
Malignant Neoplasm Progression Death Female 117 lb 12/3/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/20/2010 65 Female 91 lb 12/16/2010 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/15/2010 77 Female 123 lb 12/17/2010 Physician Brazil
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 11/11/2010 68 Female 12/21/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 11/11/2010 69 Female 12/29/2010 Physician Japan
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 9/22/2007 44 Female 1/3/2011 Physician Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Death 10/15/2010 77 Female 123 lb 1/5/2011 Physician Brazil
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/15/2010 77 Female 123 lb 1/7/2011 Physician Brazil
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious Male 1/21/2011 Other Health Professional United States
Primary
Secondary
Papilloedema Other Serious Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Papilloedema Other Serious Male 2/8/2011 Other Health Professional United States
Primary
Secondary
Myalgia Disability 3/1/2007 35 Female 2/8/2011 Physician Finland
Primary
Concomitant
Fatigue Hospitalization 78 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 54 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 55 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 70 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 65 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 37 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Ataxia Hospitalization 47 Female 2/24/2011 Physician France
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 11/11/2010 68 Female 88 lb 2/25/2011 Physician Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 47 Female 2/25/2011 Physician France
Primary
Secondary
Concomitant
Leukopenia Hospitalization 12/4/2010 58 Female 157 lb 3/2/2011 Physician Spain
Primary
Secondary
Concomitant

Drug Data