Fluorouracil combined with Oxaliplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Perforation Other Serious 53 Male 104 lb 1/3/2006 Other Health Professional Japan
Primary
Secondary
Tremor Other Serious 5/25/2005 69 Male 132 lb 1/4/2006 Physician Switzerland
Primary
Secondary
Concomitant
Ulcer Death 10/27/2005 Male 1/5/2006 Other Health Professional United States
Primary
Secondary
Odynophagia Hospitalization 1/2/2006 Male 165 lb 1/9/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Life Threatening 4/13/2005 Male 1/9/2006 Physician Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 12/21/2005 Male 154 lb 12/27/2005 United States
Primary
Secondary
Tremor Other Serious 5/25/2005 69 Male 132 lb 1/9/2006 Physician Switzerland
Primary
Secondary
Concomitant
Tremor Other Serious 5/25/2005 69 Male 132 lb 1/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Required Intervention 12/29/2005 Male 203 lb 1/5/2006 United States
Primary
Secondary
Hypovolaemia Other Serious 6/28/2004 Female 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 11/28/2005 Female 101 lb 1/13/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Oedema Other Serious 6/3/2005 Female 1/13/2006 Other Health Professional Japan
Primary
Secondary
Respiratory Rate Increased Other Serious 1/10/2006 64 Male 1/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2006 Male 162 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Death 1/18/2006 Physician United States
Primary
Secondary
Vomiting Life Threatening 9/20/2005 Male 1/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/9/2005 Female 1/18/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Thrombocytopenia Death 10/26/2005 Male 128 lb 1/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 12/2/2005 Male 123 lb 1/19/2006 Physician France
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/9/2005 Male 139 lb 1/19/2006 Other Health Professional Germany
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 1/5/2006 Male 1/20/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2005 76 Male 1/20/2006 Physician France
Primary
Secondary
Concomitant
Cholecystitis Infective Other Serious 12/27/2005 Male 1/20/2006 Other Health Professional Japan
Primary
Secondary
Sepsis Life Threatening 1/2/2006 Male 1/20/2006 Physician France
Primary
Secondary
Concomitant
Myoclonus Hospitalization 12/2/2005 Male 1/23/2006 Other Health Professional Japan
Primary
Secondary
Thrombocytopenia Other Serious 7/19/2005 Male 115 lb 1/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/2/2005 Female 1/25/2006 Other Health Professional Brazil
Primary
Secondary
Pulmonary Fibrosis Other Serious 7/6/2005 Male 97 lb 1/26/2006 Other Health Professional Japan
Primary
Secondary
Myocardial Infarction Death 1/12/2006 Male 1/26/2006 Other Health Professional Japan
Primary
Secondary
Upper Gastrointestinal Haemorrhage Other Serious 6/28/2004 Female 1/26/2006 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2006 Male 162 lb 1/27/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/29/2005 Male 139 lb 1/26/2006 Other Health Professional Japan
Primary
Secondary
Paraesthesia Hospitalization 12/2/2005 Male 130 lb 1/27/2006 Other Health Professional Japan
Primary
Secondary
Asthma Other Serious 1/16/2006 Female 1/30/2006 Other Health Professional Japan
Primary
Secondary
Oesophagitis Life Threatening 11/5/2005 Male 205 lb 1/31/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pneumatosis Hospitalization 3/10/2005 Male 162 lb 1/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2006 73 Male 141 lb 1/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 11/28/2005 Female 101 lb 2/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Death 10/12/2005 59 Female 99 lb 2/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 8/12/2005 67 Male 143 lb 2/2/2006 Other Health Professional Japan
Primary
Secondary
Syncope Other Serious 7/23/2005 80 Female 108 lb 2/2/2006 Other Health Professional Japan
Primary
Secondary
Respiratory Rate Increased Other Serious 1/10/2006 64 Male 2/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Ulcerative Life Threatening 11/12/2005 Female 2/3/2006 Physician France
Primary
Secondary
Enterocolitis Hospitalization 9/12/2004 Male 2/3/2006 Other Health Professional Norway
Primary
Secondary
Cholelithiasis Hospitalization 1/16/2005 56 Female 200 lb 1/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Infarction Other Serious 9/6/2005 68 Male 143 lb 2/7/2006 Other Health Professional Japan
Primary
Secondary
Syncope Hospitalization 1/23/2006 Female 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 2/1/2006 56 Male 2/8/2006 Other Health Professional Japan
Primary
Secondary
Paraesthesia Other Serious 11/1/2005 Female 154 lb 2/8/2006 Other Health Professional United States
Primary
Concomitant
Amaurosis Fugax Other Serious 1/18/2006 60 Female 2/6/2006 Physician Germany
Primary
Concomitant
Pneumatosis Hospitalization 3/10/2005 Male 162 lb 2/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 10/6/2005 Male 93 lb 2/10/2006 Other Health Professional Japan
Primary
Secondary
Therapy Non-responder Hospitalization 1/7/2006 38 Female 255 lb 2/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2005 56 Female 166 lb 1/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Ulcerative Life Threatening 11/12/2005 Female 2/13/2006 Physician France
Primary
Secondary
Leukopenia Other Serious 2/13/2006 Physician Italy
Primary
Secondary
Leukopenia Other Serious 2/15/2006 Physician Italy
Primary
Secondary
Cardiac Arrest Death 11/24/2005 Male 99 lb 2/15/2006 Other Health Professional Japan
Primary
Secondary
Polyuria Other Serious 10/7/2005 71 Male 132 lb 2/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastases To Bone Other Serious 11/12/2005 Male 119 lb 2/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 12/29/2005 2/15/2006 Other Health Professional United States
Primary
Secondary
Throat Tightness Required Intervention 1/31/2006 Female 112 lb 2/9/2006 United States
Primary
Secondary
Leukopenia Death Male 2/16/2006 Other Health Professional Japan
Primary
Secondary
Toxic Skin Eruption Hospitalization 2/6/2006 43 Female 2/16/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/11/2005 63 Male 2/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/8/2006 Male 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Dysphagia Hospitalization 2/6/2006 Male 159 lb 2/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Peritonitis Life Threatening 7/26/2005 Male 2/20/2006 Other Health Professional Bulgaria
Primary
Secondary
Atrial Fibrillation Hospitalization 2/3/2006 Male 2/22/2006 Physician United Kingdom
Primary
Secondary
Infection Hospitalization 1/30/2006 Female 2/22/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Bone Marrow Failure Death Male 2/23/2006 Other Health Professional Japan
Primary
Secondary
Thrombocytopenia Other Serious 10/26/2005 Male 128 lb 2/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Disability 5/22/2005 50 Male 2/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Death 12/8/2005 Male 110 lb 2/23/2006 Other Health Professional Japan
Primary
Secondary
Respiratory Rate Increased Other Serious 1/10/2006 64 Male 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 2/17/2006 46 Female 129 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Status Asthmaticus Life Threatening 1/16/2006 Female 128 lb 2/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/17/2006 Physician France
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 9/12/2004 Male 2/27/2006 Other Health Professional Norway
Primary
Secondary
Intestinal Obstruction Death 2/14/2006 82 Male 2/27/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2006 73 Male 2/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vocal Cord Paralysis Disability 7/1/2005 52 Female 166 lb 2/22/2006 Physician United States
Primary
Concomitant
Central Line Infection Hospitalization 8/19/2004 61 Male 154 lb 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 2/23/2006 56 Female 2/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/21/2006 Male 3/1/2006 Other Health Professional France
Primary
Secondary
Stomatitis Death 5/27/2005 Female 130 lb 3/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 10/2/2005 64 Male 134 lb 3/2/2006 Other Health Professional Japan
Primary
Secondary
Liver Function Test Abnormal Other Serious 1/1/2005 3/3/2006 Physician United States
Primary
Secondary
Large Intestine Perforation Hospitalization 2/25/2006 70 Male 2/28/2006 Pharmacist United States
Primary
Secondary
Deep Vein Thrombosis Hospitalization 2/23/2006 56 Female 2/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/1/2005 57 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Rectal Perforation Other Serious 5/12/2005 Male 128 lb 3/6/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Death 7/16/2005 Male 192 lb 3/6/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/14/2005 Male 126 lb 3/6/2006 Other Health Professional Japan
Primary
Secondary
Thrombocytopenia Other Serious 11/28/2005 Male 3/6/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/17/2005 73 Male 141 lb 3/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 2/1/2006 Male 115 lb 3/7/2006 Other Health Professional Japan
Primary
Secondary
Cerebral Haemorrhage Life Threatening 2/22/2006 57 Male 3/8/2006 Other Health Professional Japan
Primary
Concomitant
Sepsis Hospitalization 12/27/2005 Male 101 lb 3/8/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sudden Death Death 2/17/2006 Male 159 lb 3/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/29/2006 52 Male 3/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Hospitalization 48 Male 3/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/14/2005 Male 126 lb 3/9/2006 Other Health Professional Japan
Primary
Secondary
Mental Status Changes Other Serious 11/6/2005 Male 3/9/2006 Physician United States
Primary
Secondary
Shock Death 10/27/2005 Male 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2006 73 Male 141 lb 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/15/2006 Male 3/10/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/8/2005 Female 108 lb 3/13/2006 Other Health Professional Japan
Primary
Secondary
Pneumonia Other Serious 9/6/2005 Female 117 lb 3/14/2006 Other Health Professional Japan
Primary
Secondary
Hypertriglyceridaemia Other Serious 8/6/2005 Male 3/14/2006 Physician Germany
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 8/11/2005 Male 132 lb 3/15/2006 Other Health Professional Japan
Primary
Secondary
Arrhythmia Hospitalization 2/28/2006 Male 3/15/2006 Physician Canada
Primary
Secondary
Syncope Hospitalization 6/30/2005 62 Male 3/15/2006 Physician United States
Primary
Secondary
Haematocrit Decreased Hospitalization 8/1/2004 70 Male 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Colitis Ulcerative Life Threatening 11/12/2005 Female 3/16/2006 Physician France
Primary
Secondary
Tremor Life Threatening 2/14/2006 Male 3/16/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/14/2005 Female 108 lb 3/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/15/2006 Male 3/21/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/22/2005 61 Female 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 2/22/2006 Male 106 lb 3/24/2006 Other Health Professional Japan
Primary
Concomitant
Toxic Skin Eruption Disability 2/6/2006 Female 126 lb 3/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 12/2/2005 Male 3/24/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/17/2005 Female 97 lb 3/27/2006 Other Health Professional Japan
Primary
Secondary
Mental Status Changes Other Serious 11/6/2005 Male 3/27/2006 Physician United States
Primary
Secondary
Pulmonary Tuberculosis Hospitalization 55 Male 3/27/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 1/7/2006 42 Female 3/21/2006 United States
Primary
Secondary
Death Death 10/28/2005 56 Female 3/28/2006 Other Health Professional Germany
Primary
Secondary
Performance Status Decreased Hospitalization 6/14/2005 Female 137 lb 3/29/2006 Other Health Professional Japan
Primary
Secondary
Blood Lactate Dehydrogenase Increased Other Serious 1/25/2006 Male 3/30/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/27/2005 Male 255 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 5/12/2005 Male 128 lb 3/31/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 9/14/2005 Male 132 lb 3/31/2006 Other Health Professional Japan
Primary
Secondary
Pyrexia Other Serious 9/29/2005 Female 97 lb 3/24/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/28/2004 Male 4/3/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 2/28/2006 Male 4/3/2006 Physician Canada
Primary
Secondary
Ventricular Fibrillation Life Threatening 2/14/2006 Male 4/4/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/30/2005 62 Male 3/31/2006 United States
Primary
Secondary
Thrombocytopenia Life Threatening 9/14/2005 Male 126 lb 4/6/2006 Other Health Professional Japan
Primary
Secondary
Thrombocytopenia Other Serious 11/8/2005 Female 108 lb 4/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Arrest Death 2/14/2006 82 Male 123 lb 4/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Enteritis Hospitalization 9/12/2004 Male 4/10/2006 Other Health Professional Norway
Primary
Secondary
Cystitis Other Serious 7/28/2005 Male 4/10/2006 Other Health Professional Japan
Primary
Secondary
Pyrexia Hospitalization 3/8/2005 67 Female 4/11/2006 Consumer United States
Primary
Secondary
Weight Decreased Hospitalization 10/19/2005 Female 4/11/2006 Physician France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 9/3/2005 Male 139 lb 4/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Mesenteric Vein Thrombosis Other Serious 1/2/2006 Male 4/11/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Hospitalization 1/30/2006 Female 4/12/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Impaired Healing Female 3/1/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred 70 Male 3/1/2006 United States
Primary
Concomitant

Drug Data