Fluorouracil combined with Leucovorin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Odynophagia Hospitalization 1/2/2006 Male 165 lb 1/9/2006 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 12/21/2005 Male 154 lb 12/27/2005 United States
Primary
Secondary
Tremor Other Serious 5/25/2005 69 Male 132 lb 1/9/2006 Physician Switzerland
Primary
Secondary
Concomitant
Tremor Other Serious 5/25/2005 69 Male 132 lb 1/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Cryptogenic Organizing Pneumonia Other Serious 9/1/2004 30 Female 1/11/2006 Physician Chile
Primary
Concomitant
Hypovolaemia Other Serious 6/28/2004 Female 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 1/10/2006 64 Male 1/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2006 Male 162 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Death 1/18/2006 Physician United States
Primary
Secondary
Vomiting Life Threatening 9/20/2005 Male 1/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 12/2/2005 Male 123 lb 1/19/2006 Physician France
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 11/18/2005 Male 150 lb 1/20/2006 Other Health Professional Korea, Republic Of
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2005 76 Male 1/20/2006 Physician France
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/2/2006 Male 1/20/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/2/2005 Female 1/25/2006 Other Health Professional Brazil
Primary
Secondary
Upper Gastrointestinal Haemorrhage Other Serious 6/28/2004 Female 1/26/2006 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2006 Male 162 lb 1/27/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2006 73 Male 141 lb 1/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Disability 9/6/2005 35 Female 107 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 1/10/2006 64 Male 2/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Ulcerative Life Threatening 11/12/2005 Female 2/3/2006 Physician France
Primary
Secondary
Enterocolitis Hospitalization 9/12/2004 Male 2/3/2006 Other Health Professional Norway
Primary
Secondary
Stridor Life Threatening 1/9/2006 Female 161 lb 2/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Syncope Hospitalization 1/23/2006 Female 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumatosis Hospitalization 3/10/2005 Male 162 lb 2/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/10/2006 73 Female 2/9/2006 Consumer United States
Primary
Concomitant
Colitis Ulcerative Life Threatening 11/12/2005 Female 2/13/2006 Physician France
Primary
Secondary
Myocardial Ischaemia Hospitalization 12/29/2005 2/15/2006 Other Health Professional United States
Primary
Secondary
Dysphagia Hospitalization 2/6/2006 Male 159 lb 2/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Peritonitis Life Threatening 7/26/2005 Male 2/20/2006 Other Health Professional Bulgaria
Primary
Secondary
Atrial Fibrillation Hospitalization 2/3/2006 Male 2/22/2006 Physician United Kingdom
Primary
Secondary
Infection Hospitalization 1/30/2006 Female 2/22/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Arterial Thrombosis Hospitalization 2/10/2006 71 Female 168 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 1/10/2006 64 Male 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization Male 2/23/2006 Physician United States
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 9/12/2004 Male 2/27/2006 Other Health Professional Norway
Primary
Secondary
Renal Failure Acute Hospitalization 1/17/2006 73 Male 2/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/23/2005 62 Male 240 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Haematocrit Decreased Hospitalization 8/1/2004 70 Male 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/13/2006 62 Male 183 lb 3/11/2006 Germany
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 12/2/2005 Male 3/24/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Urinary Retention Other Serious 55 Male 3/21/2006 Physician Japan
Primary
Secondary
Mental Status Changes Other Serious 11/6/2005 Male 3/27/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 1/7/2006 42 Female 3/21/2006 United States
Primary
Secondary
Blood Lactate Dehydrogenase Increased Other Serious 1/25/2006 Male 3/30/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Photodermatosis Other Serious 68 Female 3/24/2006 Greece
Primary
Secondary
Platelet Count Decreased Hospitalization 12/27/2005 Male 255 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Viral Infection Life Threatening 1/1/2004 56 Female 128 lb 3/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/28/2004 Male 4/3/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 2/28/2006 Male 4/3/2006 Physician Canada
Primary
Secondary
Cardiomyopathy Other Serious 4/3/2006 Physician United States
Primary
Secondary
Ventricular Fibrillation Life Threatening 2/14/2006 Male 4/4/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/30/2005 62 Male 3/31/2006 United States
Primary
Secondary
Enteritis Hospitalization 9/12/2004 Male 4/10/2006 Other Health Professional Norway
Primary
Secondary
Pyrexia Hospitalization 3/8/2005 67 Female 4/11/2006 Consumer United States
Primary
Secondary
Weight Decreased Hospitalization 10/19/2005 Female 4/11/2006 Physician France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 9/3/2005 Male 139 lb 4/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Mesenteric Vein Thrombosis Other Serious 1/2/2006 Male 4/11/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/19/2006 55 Male 4/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 1/30/2006 Female 4/12/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 10/31/2005 Male 4/12/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Oesophagitis Death 3/1/2006 Female 4/14/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/21/2005 Male 139 lb 4/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Infection Hospitalization 1/30/2006 Female 4/14/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Fungaemia Hospitalization 2/21/2005 67 Female 4/18/2006 Other Health Professional United States
Primary
Secondary
Blindness Other Serious Male 4/20/2006 Other Health Professional United States
Primary
Secondary
Hypoaesthesia Hospitalization 1/1/2006 53 Male 4/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Laryngospasm Hospitalization 1/12/2006 Female 4/21/2006 Other Health Professional Sweden
Primary
Concomitant
Oesophagitis Death 3/1/2006 Female 4/24/2006 Consumer Australia
Primary
Secondary
Concomitant
Troponin I Hospitalization 2/21/2006 Male 4/26/2006 Other Health Professional United States
Primary
Secondary
Tenderness Hospitalization 4/18/2006 Male 198 lb 4/26/2006 Physician Jordan
Primary
Concomitant
Tenderness Hospitalization 4/16/2006 Male 143 lb 4/26/2006 Physician Jordan
Primary
Concomitant
Angina Pectoris Hospitalization 2/8/2006 Male 4/26/2006 Other Health Professional United States
Primary
Secondary
Yawning Other Serious 10/10/2005 54 Female 260 lb 2/15/2006 Other Health Professional United States
Primary
Concomitant
Lung Infiltration Hospitalization 4/27/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/2/2005 Female 4/27/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/4/2006 72 Male 176 lb 4/22/2006 Physician Germany
Primary
Secondary
Pyrexia Life Threatening 1/1/2006 Male 209 lb 5/2/2006 Physician United States
Primary
Concomitant
Peripheral Sensory Neuropathy Life Threatening 1/1/2006 Male 4/29/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 4/7/2006 Female 5/3/2006 Other Health Professional Mexico
Primary
Secondary
Syncope Hospitalization 2/27/2006 Female 5/4/2006 Other Health Professional United States
Primary
Secondary
Peripheral Sensory Neuropathy Life Threatening 1/1/2006 Male 4/29/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/4/2006 72 Male 176 lb 5/3/2006 Physician Germany
Primary
Secondary
Troponin I Hospitalization 2/21/2006 Male 5/5/2006 Other Health Professional United States
Primary
Secondary
Thrombosis Hospitalization 4/3/2006 Male 176 lb 5/5/2006 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 4/12/2006 43 Female 148 lb 5/3/2006 Other Health Professional United States
Primary
Secondary
Oedema Peripheral Hospitalization 8/26/2005 Male 386 lb 5/9/2006 Other Health Professional United States
Primary
Secondary
Rash Pustular 1/26/2006 Female 5/4/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/12/2006 56 Male 161 lb 5/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 Female 169 lb 5/10/2006 Physician United States
Primary
Secondary
Concomitant
Hepatitis Toxic Hospitalization 3/22/2006 Female 5/11/2006 Other Health Professional Bulgaria
Primary
Secondary
Ventricular Extrasystoles Hospitalization 2/28/2006 Male 5/11/2006 Physician Canada
Primary
Secondary
Vomiting Hospitalization 11/10/2004 Male 101 lb 5/11/2006 Other Health Professional Thailand
Primary
Secondary
Concomitant
Malignant Hypertension Other Serious 58 Female 5/16/2006 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 2/15/2006 Male 5/16/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 5/14/2006 Male 201 lb 5/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Hypertension Other Serious 5/17/2006 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 5/4/2005 Female 91 lb 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/18/2006 Physician United States
Primary
Secondary
Pancreatic Carcinoma Recurrent Death 38 Male 5/11/2006 Physician Greece
Primary
Concomitant
Pyrexia Hospitalization 3/8/2005 67 Female 5/25/2006 Consumer United States
Primary
Secondary
Pancreatitis Other Serious 5/26/2006 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 5/1/2006 Female 169 lb 5/26/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/12/2006 56 Male 161 lb 5/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Magnesium Decreased Other Serious 1/10/2005 55 Male 183 lb 5/30/2006 Consumer United States
Primary
Concomitant
Dermatitis Acneiform Other Serious 40 Male 5/30/2006 Consumer United States
Primary
Concomitant
Blood Pressure Decreased 2/22/2006 65 Female 5/30/2006 Consumer United States
Primary
Concomitant
Chills 11/1/2005 72 Male 185 lb 5/30/2006 Consumer United States
Primary
Concomitant
Urticaria Hospitalization 9/26/2005 60 Male 145 lb 5/29/2006 Other Health Professional United States
Primary
Concomitant
Neuropathy Hospitalization Male 5/29/2006 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 5/14/2006 Male 201 lb 5/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/22/2005 61 Female 134 lb 5/30/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/9/2006 Female 5/29/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 4/12/2006 43 Female 148 lb 5/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Acute Hospitalization 1/10/2006 Male 175 lb 6/1/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 4/19/2006 Male 271 lb 6/1/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 11/10/2004 Male 101 lb 6/1/2006 Other Health Professional Thailand
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/2/2006 Male 6/2/2006 Physician France
Primary
Secondary
Concomitant
Syncope Hospitalization 4/10/2006 Male 6/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/19/2006 Male 185 lb 6/7/2006 Other Health Professional United States
Primary
Secondary
Visual Disturbance Other Serious 45 Female 6/7/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 5/4/2006 60 Female 185 lb 6/1/2006 Germany
Primary
Secondary
Concomitant
Thrombosis Life Threatening 4/3/2006 6/8/2006 Other Health Professional United States
Primary
Secondary
Sepsis Life Threatening 1/25/2005 Male 6/13/2006 Physician Canada
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 5/24/2006 6/13/2006 Other Health Professional United States
Primary
Secondary
Rash Other Serious 5/31/2006 50 Male 172 lb 5/31/2006 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 5/25/2006 Male 166 lb 6/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 4/3/2006 69 Female 6/14/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 3/4/2006 72 Male 176 lb 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/4/2006 72 Male 176 lb 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 5/14/2006 Male 201 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/25/2005 Male 6/16/2006 Physician Canada
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 6/28/2005 Female 6/19/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Neuropathy Hospitalization 4/17/2006 Male 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Erythematous Disability 3/7/2006 34 Male 6/14/2006 Pharmacist United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 7/27/2005 Female 6/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/20/2005 72 Male 192 lb 6/23/2006 Other Health Professional Czech Republic
Primary
Secondary
Coma Other Serious 75 Male 6/27/2006 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 75 Male 7/17/2006 Physician Korea, Republic Of
Primary
Secondary
Malnutrition Hospitalization 1/5/2006 Male 7/17/2006 Physician France
Primary
Secondary
White Blood Cell Count Decreased Other Serious 8/9/2006 60 Female 101 lb 8/30/2006 United States
Primary
Secondary
Concomitant
Sensory Loss Male 8/30/2006 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 8/9/2006 73 Male 187 lb 8/31/2006 Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/23/2006 71 Male 150 lb 8/31/2006 Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/9/2006 56 Male 176 lb 8/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 6/9/2006 56 Male 176 lb 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 7/19/2006 67 Female 110 lb 9/11/2006 Other Health Professional United States
Primary
Secondary
Syncope Vasovagal Other Serious 8/10/2006 52 Male 163 lb 9/12/2006 Consumer United States
Primary
Secondary
Concomitant
Malaise Hospitalization 5/10/2006 79 Female 9/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/13/2006 Other Health Professional Korea, Republic Of
Primary
Concomitant

Drug Data