Fluorouracil combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 11/18/2005 Male 150 lb 1/4/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Tremor Other Serious 5/25/2005 69 Male 132 lb 1/4/2006 Physician Switzerland
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 75 Female 1/4/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/19/2005 68 Female 152 lb 1/9/2006 Physician Australia
Primary
Secondary
Sepsis Other Serious 8/26/2005 Female 110 lb 1/3/2005 United States
Primary
Secondary
Dyspnoea Other Serious 11/30/2005 Male 287 lb 1/9/2006 United States
Primary
Secondary
Non-cardiac Chest Pain Required Intervention 12/29/2005 Male 203 lb 1/5/2006 United States
Primary
Secondary
Peritonitis Hospitalization 11/25/2005 53 Male 1/10/2006 Physician Finland
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 10/30/2005 68 Male 198 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Pneumoperitoneum Hospitalization 12/9/2005 Male 155 lb 1/12/2006 Physician Spain
Primary
Secondary
Vomiting Hospitalization 6/5/2005 57 Male 1/13/2006 Physician United States
Primary
Concomitant
Tremor Hospitalization 11/21/2005 56 Female 106 lb 1/13/2006 Physician Canada
Primary
Secondary
Concomitant
Ileus Hospitalization 10/21/2005 51 Female 1/13/2006 Physician Czech Republic
Primary
Concomitant
Urosepsis Disability 10/8/2005 66 Male 1/18/2006 Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/18/2005 68 Female 152 lb 1/18/2006 Physician Australia
Primary
Secondary
Tremor Hospitalization 11/21/2005 56 Female 106 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/28/2005 42 Female 205 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Post Procedural Vomiting Life Threatening 9/30/2005 62 Male 166 lb 1/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Testicular Disorder Hospitalization 10/30/2005 68 Male 198 lb 1/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 1/10/2006 Male 200 lb 1/17/2006 United States
Primary
Secondary
Lymphoma Other Serious Female 1/19/2006 Physician United States
Primary
Secondary
Vomiting Other Serious 1/7/2006 Female 108 lb 1/16/2006 United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 52 Female 1/20/2006 Physician United States
Primary
Secondary
Gastritis Hospitalization 9/11/2005 57 Female 180 lb 1/20/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/25/2005 63 Female 101 lb 1/24/2006 Other Health Professional Canada
Primary
Secondary
White Blood Cell Count Increased Hospitalization 11/22/2005 74 Male 437 lb 1/24/2006 Physician Australia
Primary
Secondary
Concomitant
Stridor Other Serious 1/9/2006 Female 161 lb 1/31/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Oesophagitis Life Threatening 11/5/2005 Male 205 lb 1/31/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pneumatosis Hospitalization 3/10/2005 Male 162 lb 1/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/4/2005 53 Male 182 lb 1/25/2006 Physician United Kingdom
Primary
Secondary
Leukopenia Hospitalization 10/25/2005 73 Female 112 lb 1/25/2006 Physician Bulgaria
Primary
Secondary
Concomitant
Death Death 59 Male 1/26/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Small Intestinal Perforation Hospitalization 11/25/2005 53 Male 1/26/2006 Physician Finland
Primary
Concomitant
Pyrexia Life Threatening 12/1/2005 75 Female 1/27/2006 Physician France
Primary
Concomitant
Neuropathy Disability 5/31/2005 49 Female 132 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Non-cardiac Chest Pain Disability 8/31/2005 51 Female 185 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Neurotoxicity Disability 5/5/2005 64 Male 188 lb 12/1/2005 Physician United States
Primary
Concomitant
Oedema Peripheral Disability 4/1/2005 64 Male 188 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Neuropathy Disability 8/1/2005 55 Female 12/1/2005 Physician United States
Primary
Secondary
Oxygen Saturation Decreased Other Serious 5/16/2005 58 Male 249 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Shoulder Pain Hospitalization 7/28/2005 74 Female 213 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2005 68 Male 1/30/2006 United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 1/10/2006 64 Male 1/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Scab Other Serious 55 Male 2/1/2006 Physician Netherlands
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 1/22/2006 Female 280 lb 1/26/2006 United States
Primary
Secondary
Concomitant
Appendicitis Hospitalization 9/8/2005 68 Male 211 lb 2/1/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 59 Male 345 lb 2/2/2006 Canada
Primary
Secondary
Concomitant
Viral Infection Hospitalization 1/13/2006 39 Female 227 lb 2/2/2006 Physician United States
Primary
Secondary
Concomitant
Shoulder Pain Hospitalization 12/21/2005 60 Female 126 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Abscess Hospitalization 1/13/2006 25 Male 187 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/21/2005 60 Male 2/6/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Hand-foot-and-mouth Disease Hospitalization 68 Male 2/3/2006 Physician France
Primary
Concomitant
Weight Decreased Required Intervention 2/3/2006 Male 164 lb 2/6/2006 United States
Primary
Secondary
Renal Failure Acute Hospitalization 1/17/2006 73 Male 141 lb 2/7/2006 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Life Threatening 9/20/2005 52 Female 2/8/2006 Physician United States
Primary
Secondary
Pulmonary Embolism Required Intervention 2/5/2006 Female 214 lb 2/7/2006 United States
Primary
Secondary
Polyuria Other Serious 10/7/2005 71 Male 132 lb 2/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Urticaria Generalised Hospitalization 12/4/2005 53 Male 182 lb 2/9/2006 Physician United Kingdom
Primary
Secondary
Throat Tightness Required Intervention 1/31/2006 Female 112 lb 2/9/2006 United States
Primary
Secondary
Pulmonary Embolism Required Intervention 2/4/2006 Female 195 lb 2/6/2006 United States
Primary
Secondary
Diabetes Mellitus Other Serious Male 2/16/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/24/2006 57 Female 203 lb 2/10/2006 Physician South Africa
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/11/2005 63 Male 2/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Death NotSpecified 1/13/2006 Physician United States
Primary
Secondary
Proteinuria Required Intervention 1/30/2006 Male 269 lb 2/9/2006 United States
Primary
Secondary
Neutropenia Other Serious 1/13/2006 62 Male 183 lb 2/14/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Diabetes Mellitus Disability 50 Male 2/22/2006 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Gastrointestinal Infection Hospitalization 12/29/2005 57 2/15/2006 Physician United States
Primary
Secondary
Pain Other Serious 2/14/2006 Female 183 lb 2/17/2006 United States
Primary
Secondary
Pulmonary Embolism Required Intervention 2/14/2006 Male 246 lb 2/15/2006 United States
Primary
Secondary
Gastrointestinal Stoma Complication Other Serious 2/11/2006 Male 150 lb 2/20/2006 United States
Primary
Secondary
Vomiting Other Serious 2/6/2006 Male 150 lb 2/17/2006 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 2/11/2006 Female 181 lb 2/16/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/22/2006 54 Female 2/15/2006 Physician Canada
Primary
Secondary
Concomitant
Clostridium Colitis Other Serious 11/20/2005 76 Male 2/16/2006 United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 1/10/2006 64 Male 1/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Life Threatening 7/26/2005 55 Male 176 lb 2/17/2006 Physician Bulgaria
Primary
Secondary
Skin Ulcer Other Serious 2/6/2006 Male 173 lb 2/14/2006 United States
Primary
Secondary
Nephrolithiasis Hospitalization 2/17/2006 46 Female 129 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/19/2005 81 Female 1/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/17/2006 Physician France
Primary
Secondary
Concomitant
Ascites Required Intervention 11/6/2005 54 Male 177 lb 2/21/2006 United States
Primary
Secondary
Thrombosis Hospitalization 2/7/2006 Female 2/22/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Hypoxia Hospitalization 60 Female 2/22/2006 Physician France
Primary
Concomitant
Vocal Cord Paralysis Disability 7/1/2005 52 Female 166 lb 2/22/2006 Physician United States
Primary
Concomitant
Central Line Infection Hospitalization 8/19/2004 61 Male 154 lb 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 2/7/2006 53 Female 214 lb 2/23/2006 Physician Australia
Primary
Secondary
Nasal Septum Perforation Other Serious 53 Male 2/27/2006 Physician United States
Primary
Concomitant
Skin Ulcer Death 10/27/2005 76 Male 2/24/2006 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/25/2006 40 Female 2/24/2006 Physician Norway
Primary
Concomitant
Metastases To Liver Hospitalization 5/4/2005 84 Male 159 lb 2/27/2006 Physician United States
Primary
Secondary
Concomitant
Rash Pustular 9/30/2005 26 Female 3/3/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 12/1/2005 60 Female 130 lb 3/3/2006 Consumer United States
Primary
Concomitant
No Adverse Effect 1/10/2006 72 Male 3/3/2006 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 3/3/2006 Physician United States
Primary
Secondary
Sepsis Death 5/17/2005 Male 139 lb 3/3/2006 Physician Korea, Republic Of
Primary
Concomitant
Fatigue Hospitalization 12/1/2005 73 Female 2/28/2006 Physician Canada
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/25/2006 70 Male 2/28/2006 Pharmacist United States
Primary
Secondary
Pulmonary Haematoma Other Serious 2/16/2006 Male 151 lb 2/21/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 1/17/2005 73 Male 141 lb 3/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Reflux Oesophagitis Other Serious Female 3/8/2006 Pharmacist Australia
Primary
Secondary
Vomiting Other Serious 11/11/2005 Female 93 lb 3/8/2006 Pharmacist Ireland
Primary
Secondary
Concomitant
Sudden Death Death 2/17/2006 Male 159 lb 3/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/29/2006 52 Male 3/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 11/6/2005 Male 3/9/2006 Physician United States
Primary
Secondary
Renal Failure Acute Hospitalization 1/1/2006 73 Male 141 lb 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/15/2006 Male 3/10/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 3/2/2006 Male 223 lb 3/9/2006 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/11/2006 59 Male 3/6/2006 Consumer United States
Primary
Concomitant
Hypertriglyceridaemia Other Serious 8/6/2005 Male 3/14/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/24/2006 57 Female 203 lb 3/9/2006 Physician South Africa
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/15/2006 64 Male 243 lb 3/7/2006 Physician United States
Primary
Secondary
Concomitant
Metastases To Lung Other Serious 80 Female 3/6/2006 United States
Primary
Concomitant
Pruritus Other Serious 8/5/2005 64 Male 153 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Type Iv Hypersensitivity Reaction Other Serious 7/10/2005 43 Female 191 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Hospitalization 8/8/2005 64 Female 189 lb 12/1/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 8/15/2005 Female 12/1/2005 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/22/2005 62 Male 12/1/2005 Other Health Professional United States
Primary
Concomitant
Arrhythmia Hospitalization 2/28/2006 Male 3/15/2006 Physician Canada
Primary
Secondary
Pruritus Generalised Hospitalization 3/2/2006 Male 143 lb 3/15/2006 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 6/30/2005 62 Male 3/15/2006 Physician United States
Primary
Secondary
Colitis Ulcerative Life Threatening 11/12/2005 Female 3/16/2006 Physician France
Primary
Secondary
Tremor Life Threatening 2/14/2006 Male 3/16/2006 Physician United States
Primary
Secondary
Concomitant
Leukoencephalomyelitis Hospitalization 55 Male 3/17/2006 Japan
Primary
Secondary
Pneumonia Death 1/1/2006 63 Male 3/17/2006 Physician Hong Kong
Primary
Concomitant
Neutropenia Life Threatening 2/7/2006 66 Female 132 lb 3/13/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/20/2006 76 Female 3/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 9/4/2005 80 Female 147 lb 3/13/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2006 73 Male 141 lb 3/13/2006 Physician United States
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 8/6/2005 54 Male 3/10/2006 Physician Germany
Primary
Secondary
Concomitant
Syncope Other Serious 10/1/2005 69 Male 3/10/2006 Physician Canada
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 51 Male 3/20/2006 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Ascites Required Intervention 11/6/2005 54 Male 177 lb 3/15/2006 Other Health Professional United States
Primary
Secondary
Thrombosis Other Serious 2/15/2006 Male 3/21/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/22/2005 61 Female 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 2/28/2006 54 Female 102 lb 3/13/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/23/2005 69 Female 3/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 11/6/2005 54 Male 177 lb 3/14/2006 Other Health Professional United States
Primary
Secondary
Vocal Cord Paralysis Hospitalization 50 Male 3/22/2006 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/28/2006 72 Male 173 lb 3/17/2006 Physician Canada
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/2/2006 70 Male 3/17/2006 Physician Thailand
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/25/2005 63 Female 101 lb 3/20/2006 Other Health Professional Canada
Primary
Secondary
Menorrhagia Hospitalization 44 Female 86 lb 3/21/2006 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/15/2006 64 Male 243 lb 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 3/16/2006 Female 172 lb 3/22/2006 United States
Primary
Secondary
Vomiting Hospitalization 2/7/2006 61 Female 3/24/2006 Physician Germany
Primary
Secondary
Drug Hypersensitivity Hospitalization 12/4/2005 53 Male 182 lb 3/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Urinary Retention Hospitalization 55 Male 3/23/2006 Physician Japan
Primary
Secondary
Nausea Other Serious 3/14/2006 61 Female 157 lb 3/29/2006 Other Health Professional Germany
Primary
Secondary
Concomitant

Drug Data