Fluorouracil combined with Isovorin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Disseminated Intravascular Coagulation Life Threatening 11/28/2005 Female 101 lb 1/13/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Myoclonus Hospitalization 12/2/2005 Male 1/23/2006 Other Health Professional Japan
Primary
Secondary
Paraesthesia Hospitalization 12/2/2005 Male 130 lb 1/27/2006 Other Health Professional Japan
Primary
Secondary
Guillain-barre Syndrome Other Serious 9/25/2005 Male 214 lb 2/1/2006 Physician South Africa
Primary
Concomitant
Thrombocytopenia Life Threatening 11/28/2005 Female 101 lb 2/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 2/6/2006 43 Female 2/16/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 9/25/2005 Male 214 lb 2/16/2006 Physician South Africa
Primary
Concomitant
Guillain-barre Syndrome Other Serious 9/25/2005 Male 214 lb 2/20/2006 Physician South Africa
Primary
Concomitant
Guillain-barre Syndrome Other Serious 9/25/2005 Male 214 lb 2/22/2006 Physician South Africa
Primary
Concomitant
Toxic Skin Eruption Disability 2/6/2006 Female 126 lb 3/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastases To Lymph Nodes Life Threatening 10/20/2003 Male 4/18/2006 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 2/21/2006 Male 134 lb 4/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/26/2006 Male 4/28/2006 Other Health Professional Japan
Primary
Secondary
Metastases To Lymph Nodes Life Threatening 10/20/2003 51 Male 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 3/13/2006 75 Female 6/1/2006 Physician Japan
Primary
Secondary
Vomiting Death 9/29/2005 Male 121 lb 6/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 5/24/2006 77 Male 117 lb 7/3/2006 Other Health Professional Japan
Primary
Concomitant
Pneumonia Death 7/25/2006 60 Male 8/4/2006 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection Death 7/25/2006 60 Male 112 lb 8/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/13/2006 Female 9/29/2006 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 8/17/2006 Male 106 lb 10/17/2006 Physician Japan
Primary
Secondary
Concomitant
Convulsion Hospitalization 11/1/2005 64 Male 3/14/2007 Other Health Professional Japan
Primary
Secondary
Cardiac Failure Other Serious 1/22/2007 Female 99 lb 3/27/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 3/4/2006 Female 130 lb 3/28/2007 Other Health Professional Japan
Primary
Concomitant
Gastric Ulcer Hospitalization 7/20/2005 Male 143 lb 4/2/2007 Other Health Professional Japan
Primary
Secondary
Thrombocytopenia Life Threatening 2/8/2007 Female 71 lb 4/6/2007 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 2/8/2007 Female 71 lb 4/23/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Laryngospasm Other Serious Female 4/24/2007 Physician Portugal
Primary
Concomitant
Interstitial Lung Disease Death 4/2/2007 Female 108 lb 4/25/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 1/11/2007 71 Male 134 lb 5/7/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Laryngospasm Other Serious Female 5/15/2007 Physician Portugal
Primary
Concomitant
Interstitial Lung Disease Death 4/2/2007 Female 108 lb 5/23/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 3/22/2007 Female 121 lb 5/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Death 4/26/2007 Female 104 lb 5/29/2007 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/30/2005 Male 112 lb 6/1/2007 Other Health Professional Japan
Primary
Secondary
Upper Gastrointestinal Haemorrhage Death 5/4/2007 Male 6/1/2007 Other Health Professional Japan
Primary
Secondary
Shock Death 5/10/2007 Male 97 lb 6/5/2007 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 5/24/2007 53 Male 6/5/2007 Other Health Professional Japan
Primary
Concomitant
Subdural Haematoma Other Serious 1/11/2007 71 Male 134 lb 6/6/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/31/2006 Male 6/13/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 6/8/2007 74 Male 7/3/2007 Other Health Professional Japan
Primary
Concomitant
Shock Death 5/10/2007 Male 97 lb 7/6/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Encephalopathy Other Serious 63 Female 7/9/2007 Other Health Professional Japan
Primary
Secondary
Pneumothorax Other Serious 10/4/2005 Male 146 lb 7/18/2007 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 67 Female 7/18/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 4/6/2007 Male 157 lb 7/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 5/4/2007 Male 123 lb 7/24/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/3/2007 63 Female 108 lb 7/26/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/3/2007 62 Female 108 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/22/2007 Male 117 lb 8/3/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 8/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pupils Unequal Hospitalization 7/21/2007 Male 8/15/2007 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 8/2/2007 Female 8/15/2007 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 50 Male 8/20/2007 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 8/16/2006 Male 187 lb 8/22/2007 Physician Japan
Primary
Secondary
Pyrexia Hospitalization 8/2/2007 Female 101 lb 8/23/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 8/29/2007 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/3/2007 62 Female 108 lb 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/3/2007 62 Female 108 lb 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Field Defect Hospitalization 8/20/2007 Male 9/7/2007 Consumer United Kingdom
Primary
Secondary
Muscular Weakness Life Threatening 8/24/2007 Female 9/12/2007 Physician United Kingdom
Primary
Secondary
Appendicitis Perforated Hospitalization 8/5/2007 Male 9/13/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 7/21/2007 Male 9/14/2007 Consumer United Kingdom
Primary
Secondary
Bone Marrow Failure Hospitalization 8/16/2007 Female 9/20/2007 Physician United Kingdom
Primary
Secondary
Hypoaesthesia Life Threatening 8/24/2007 Female 9/21/2007 Physician United Kingdom
Primary
Secondary
Upper Gastrointestinal Haemorrhage Death 5/4/2007 Male 123 lb 9/26/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Pulmonary Oedema Death 9/15/2007 Female 10/3/2007 Consumer United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 8/22/2007 Male 10/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 7/23/2007 Male 10/3/2007 Physician United Kingdom
Primary
Secondary
Fall Hospitalization 8/20/2007 Male 10/5/2007 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Death 9/15/2007 Female 10/5/2007 Consumer United Kingdom
Primary
Concomitant
Liver Disorder Hospitalization 9/19/2007 55 Male 10/5/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 9/3/2007 32 Male 205 lb 10/9/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Intestinal Fistula Life Threatening 9/5/2007 Female 10/10/2007 Physician Japan
Primary
Secondary
Concomitant
Fall Hospitalization 8/20/2007 Male 10/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/11/2007 Male 10/11/2007 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/2/2007 Female 101 lb 10/11/2007 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Abnormal Death 9/26/2007 Male 10/11/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 8/27/2007 Male 10/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 9/17/2007 Male 10/11/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/25/2007 Female 79 lb 10/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/12/2007 Male 10/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 9/4/2007 Female 10/16/2007 Physician United Kingdom
Primary
Concomitant
Nausea Hospitalization 8/16/2007 Female 10/16/2007 Physician United Kingdom
Primary
Secondary
Pyrexia Death Male 10/23/2007 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Death 9/5/2007 Female 10/24/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 9/4/2007 Female 10/25/2007 Physician United Kingdom
Primary
Concomitant
Liver Disorder Hospitalization 9/19/2007 55 Male 10/26/2007 Physician United Kingdom
Primary
Concomitant
Liver Disorder Hospitalization 9/19/2007 55 Male 10/30/2007 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 9/15/2007 Female 10/31/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Intestinal Ulcer Hospitalization 9/28/2007 Female 10/31/2007 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 10/11/2006 Male 126 lb 10/31/2007 Physician Japan
Primary
Secondary
Thrombocytopenia Death 9/15/2007 Female 11/2/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening Male 11/7/2007 Other Health Professional Japan
Primary
Secondary
Large Intestine Perforation Life Threatening 10/10/2007 66 Male 11/7/2007 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 9/19/2007 55 Male 11/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 10/11/2006 Male 126 lb 11/9/2007 Physician Japan
Primary
Secondary
Intestinal Obstruction Hospitalization 9/16/2007 Male 11/10/2007 Physician United Kingdom
Primary
Concomitant
Wound Dehiscence Death 9/5/2007 Female 11/13/2007 Consumer United Kingdom
Primary
Concomitant
Pneumonia Aspiration Death 9/26/2007 Male 11/13/2007 Physician United Kingdom
Primary
Concomitant
Large Intestine Perforation Life Threatening 10/10/2007 66 Male 11/14/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death Female 11/15/2007 Physician United Kingdom
Primary
Secondary
Liver Disorder Hospitalization 9/19/2007 55 Male 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoaesthesia Life Threatening 8/24/2007 Female 11/16/2007 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/12/2007 Male 11/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Death 9/26/2007 Male 11/21/2007 Physician United Kingdom
Primary
Concomitant
Leukopenia Other Serious 9/12/2007 Female 11/21/2007 Physician Japan
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/18/2007 Male 11/21/2007 Physician United Kingdom
Primary
Concomitant
Platelet Count Abnormal Death Female 11/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 7/23/2007 Male 11/29/2007 Physician United Kingdom
Primary
Secondary
Aortic Dissection Other Serious 10/29/2007 Male 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaphylactoid Reaction Other Serious 10/23/2007 Male 126 lb 12/3/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 9/19/2007 Female 12/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/16/2007 Male 12/5/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/4/2007 Female 12/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 12/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 11/20/2007 Male 12/7/2007 Consumer United Kingdom
Primary
Concomitant
Neutropenia Other Serious 8/29/2007 Female 99 lb 12/7/2007 Other Health Professional Japan
Primary
Concomitant
Death Death 10/11/2007 Female 12/10/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/25/2007 Female 79 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/17/2007 Female 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 8/22/2007 Male 12/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 59 Female 12/14/2007 Other Health Professional Japan
Primary
Secondary
Epistaxis Hospitalization 9/17/2007 Male 12/14/2007 Consumer United Kingdom
Primary
Concomitant
Sepsis Death 11/6/2007 Male 12/14/2007 Consumer United Kingdom
Primary
Concomitant
Shock Haemorrhagic Other Serious 10/8/2007 Male 12/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 11/24/2007 82 Female 12/13/2007 Physician Japan
Primary
Secondary
Renal Failure Acute Other Serious 9/19/2007 Female 12/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 11/20/2007 Male 12/14/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 9/4/2007 Female 12/17/2007 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 11/15/2007 Male 12/18/2007 Physician United Kingdom
Primary
Secondary
Vomiting Other Serious 9/24/2007 Male 12/18/2007 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 10/29/2007 Male 12/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/19/2007 Male 12/18/2007 Consumer United Kingdom
Primary
Concomitant
Cardiac Failure Death 9/26/2007 Male 12/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 10/15/2007 Male 12/19/2007 Consumer United Kingdom
Primary
Concomitant
Anaphylactic Shock Life Threatening 10/9/2007 Male 12/19/2007 Consumer United Kingdom
Primary
Secondary
Hepatic Failure Death 11/15/2007 Male 12/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/28/2007 Female 12/21/2007 Consumer United Kingdom
Primary
Secondary
Sepsis Death 11/20/2007 Male 12/21/2007 Consumer United Kingdom
Primary
Concomitant
Platelet Count Decreased Hospitalization 11/7/2007 Female 12/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 11/6/2007 Male 12/21/2007 Consumer United Kingdom
Primary
Concomitant
Hypersensitivity Hospitalization 11/26/2007 Male 12/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 11/22/2007 82 Female 95 lb 12/24/2007 Physician Japan
Primary
Secondary
Vomiting Life Threatening 5/22/2007 Male 117 lb 12/24/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Other Serious 12/8/2007 58 Male 12/27/2007 Physician United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 12/3/2007 40 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data