Fluorouracil combined with Irinotecan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancytopenia Life Threatening 6/13/2005 43 Female 1/23/2006 Other Health Professional Germany
Primary
Secondary
Intestinal Haemorrhage Hospitalization 3/4/2006 73 Male 3/23/2006 Other Health Professional Germany
Primary
Secondary
Venous Thrombosis Hospitalization 10/2/2005 66 Male 3/24/2006 Other Health Professional Germany
Primary
Secondary
Mucosal Inflammation Hospitalization 2/16/2006 48 Female 3/24/2006 Other Health Professional Germany
Primary
Secondary
Sepsis Death 6/7/2005 55 Female 132 lb 5/1/2006 Physician Spain
Primary
Secondary
Concomitant
Sepsis Death 6/7/2005 Female 5/2/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/7/2005 55 Female 132 lb 5/16/2006 Physician Spain
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 75 Male 5/17/2006 Physician Germany
Primary
Secondary
Sepsis Hospitalization 6/7/2005 Female 5/18/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/2/2005 71 Male 2/24/2006 Physician United States
Primary
Concomitant
Rash Other Serious 5/31/2006 50 Male 172 lb 5/31/2006 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 75 Male 6/15/2006 Physician Germany
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 6/4/2006 74 Male 6/23/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Convulsion Life Threatening 1/26/2006 69 Male 6/23/2006 Other Health Professional Germany
Primary
Secondary
Malignant Neoplasm Progression Other Serious 11/25/2005 70 Male 6/29/2006 Other Health Professional Germany
Primary
Secondary
Myocardial Infarction Hospitalization 68 Female 6/29/2006 Consumer United States
Primary
Concomitant
Venous Thrombosis Hospitalization 10/2/2005 66 Male 6/29/2006 Other Health Professional Germany
Primary
Secondary
Acute Promyelocytic Leukaemia Death 5/1/1996 65 Female 7/12/2006 Physician
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 6/4/2006 74 Male 271 lb 7/17/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 7/4/2006 66 Male 7/18/2006 Physician Germany
Primary
Concomitant
Septic Shock Other Serious 5/31/2006 58 Male 7/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Convulsion Life Threatening 1/26/2006 69 Male 7/24/2006 Other Health Professional United States
Primary
Secondary
Respiratory Tract Infection Life Threatening 9/26/2005 71 Female 7/24/2006 Consumer Germany
Primary
Secondary
Shock Other Serious 5/31/2006 58 Male 8/14/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Fibrosis Disability 5/1/2006 74 161 lb 12/27/2006 Physician Germany
Primary
Secondary
Concomitant
Hypophosphataemia Other Serious 66 Male 1/8/2007 Other Health Professional Germany
Primary
Concomitant
Venous Thrombosis Other Serious 1/7/2007 53 Female 1/25/2007 Other Health Professional Germany
Primary
Secondary
Vomiting Other Serious 7/27/2006 Female 147 lb 1/26/2007 Physician United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 10/26/2006 64 Male 1/31/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 5/26/2006 Female 167 lb 2/2/2007 Physician United States
Primary
Concomitant
Rash Hospitalization 10/27/2006 Female 2/5/2007 Physician Australia
Primary
Secondary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 2/16/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/27/2006 Male 2/19/2007 Physician Australia
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 2/26/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/19/2007 Female 3/28/2007 Physician Australia
Primary
Secondary
Paraesthesia Hospitalization Male 3/28/2007 Other Health Professional Germany
Primary
Secondary
Hypokalaemia Hospitalization 3/1/2007 Female 136 lb 4/2/2007 Physician United States
Primary
Concomitant
Nausea Hospitalization 3/17/2007 Female 4/3/2007 Physician United States
Primary
Concomitant
Hypotension Hospitalization 11/5/2006 Male 4/30/2007 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/20/2007 74 Male 4/19/2007 Germany
Primary
Secondary
Epistaxis Hospitalization 10/8/2007 Female 1/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 11/7/2007 Female 1/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/16/2006 Female 1/8/2008 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 11/23/2007 Male 176 lb 1/8/2008 Physician Australia
Primary
Secondary
Pulmonary Embolism Hospitalization 11/14/2007 Male 1/8/2008 Physician Australia
Primary
Secondary
Concomitant
Pruritus Hospitalization 12/10/2007 Female 1/8/2008 Physician Poland
Primary
Concomitant
Metastases To Liver Other Serious 12/1/2007 Male 1/9/2008 Physician United Kingdom
Primary
Secondary
Septic Shock Hospitalization 12/3/2007 Male 1/14/2008 Physician Australia
Primary
Secondary
Concomitant
Bone Disorder Other Serious 12/3/2007 Male 216 lb 1/15/2008 Other Health Professional Germany
Primary
Concomitant
Tumour Lysis Syndrome Death 62 Male 1/15/2008 Physician Germany
Primary
Concomitant
Fungal Infection Hospitalization 1/8/2008 Female 123 lb 1/17/2008 Physician Belgium
Primary
Secondary
Dermatitis Exfoliative Other Serious 11/8/2007 Female 110 lb 1/18/2008 Pharmacist United Kingdom
Primary
Concomitant
Erythema Hospitalization 9/27/2007 Female 1/18/2008 Physician Belgium
Primary
Concomitant
Diarrhoea Hospitalization 1/14/2008 Male 168 lb 1/21/2008 Physician Belgium
Primary
Secondary
Concomitant
Urinary Fistula Hospitalization 4/1/2006 Male 172 lb 1/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ileus Hospitalization 10/24/2007 58 Male 1/22/2008 Consumer United States
Primary
Secondary
Hepatic Function Abnormal Hospitalization 11/5/2007 60 Male 1/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 83 Male 1/17/2008 Physician Italy
Primary
Secondary
Intestinal Obstruction Hospitalization 12/8/2007 40 Female 1/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/20/2007 Female 1/24/2008 Physician Russian Federation
Primary
Secondary
Malnutrition Hospitalization 12/1/2007 82 Female 1/25/2008 Physician United Kingdom
Primary
Secondary
Haematemesis Hospitalization 1/13/2008 Male 1/25/2008 Physician France
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/14/2008 62 Male 1/25/2008 Other Health Professional Germany
Primary
Secondary
Myalgia Other Serious 9/1/2007 39 Female 133 lb 1/25/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 7/25/2005 78 Male 1/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Epilepsy Other Serious 37 Male 1/26/2008 Physician United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization 5/16/2007 70 Male 1/21/2008 Physician New Zealand
Primary
Secondary
Platelet Count Decreased Disability 11/7/2007 Female 1/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/14/2008 62 Male 1/30/2008 Other Health Professional Germany
Primary
Secondary
Pruritus Hospitalization 12/10/2007 Female 176 lb 1/30/2008 Physician Poland
Primary
Concomitant
Thrombosis Hospitalization 1/14/2008 Female 1/31/2008 Physician Austria
Primary
Concomitant
Vomiting Other Serious 5/1/2007 82 Female 2/1/2008 Physician Taiwan, Province Of China
Primary
Secondary
Jaundice Hospitalization 8/30/2007 Male 176 lb 2/4/2008 Physician United Kingdom
Primary
Concomitant
Haematemesis Hospitalization 1/13/2008 Male 2/6/2008 Physician France
Primary
Concomitant
Neutropenia Hospitalization 11/26/2007 Female 2/6/2008 Physician Austria
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 12/1/2007 Male 134 lb 2/7/2008 Physician United Kingdom
Primary
Secondary
Haematuria Hospitalization 1/25/2008 Female 2/11/2008 Physician Austria
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 2/11/2008 Physician Australia
Primary
Concomitant
Hyperhidrosis Hospitalization 10/2/2007 Male 256 lb 2/11/2008 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 2/2/2008 66 Female 2/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pruritus Hospitalization 12/10/2007 Female 176 lb 2/13/2008 Physician Poland
Primary
Concomitant
Tumour Lysis Syndrome Other Serious Male 2/9/2008 Other Health Professional Germany
Primary
Secondary
Tooth Extraction Other Serious 2/1/2006 56 Male 240 lb 2/14/2008 Physician Germany
Primary
Concomitant
Stomatitis Other Serious 12/1/2007 Male 2/14/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Death 12/29/2007 Male 2/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/10/2007 Male 2/20/2008 Physician Australia
Primary
Concomitant
Septic Shock Life Threatening 12/3/2007 Male 2/20/2008 Physician Australia
Primary
Secondary
Concomitant
Depression Hospitalization 2/7/2008 Male 2/20/2008 Physician France
Primary
Concomitant
Ventricular Fibrillation Death 70 Male 2/20/2008 New Zealand
Primary
Concomitant
Pyrexia Life Threatening 1/5/2008 Male 2/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/4/2007 Female 2/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 2/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 12/1/2007 Male 2/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/29/2006 62 Female 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/6/2008 Female 2/25/2008 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Disability 11/7/2007 Female 2/25/2008 Consumer Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Disability 2/8/2008 Male 2/26/2008 Physician United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization 2/12/2008 Female 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Melaena Hospitalization 1/13/2008 Male 2/27/2008 Physician France
Primary
Secondary
Concomitant
Haematuria Hospitalization 1/25/2008 Female 2/28/2008 Physician Austria
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 11/22/2007 Male 2/29/2008 Physician Ireland
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/20/2007 Female 3/4/2008 Physician Russian Federation
Primary
Secondary
Nausea Hospitalization 9/10/2007 Male 3/4/2008 Physician Ireland
Primary
Secondary
Overdose Other Serious 9/3/2007 Female 3/4/2008 Physician France
Primary
Secondary
Concomitant
Fatigue Hospitalization 2/22/2008 Male 3/5/2008 Physician United States
Primary
Concomitant
Ileus Life Threatening 9/18/2007 Female 160 lb 3/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Death 10/21/2007 Male 3/6/2008 Other Health Professional France
Primary
Concomitant
Pyrexia Hospitalization 12/21/2007 40 Female 3/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/6/2008 Female 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 3/18/2006 Male 186 lb 3/11/2008 Other Health Professional Canada
Primary
Concomitant
Haemorrhage Death 9/28/2007 Male 3/11/2008 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Other Serious Male 3/11/2008 Consumer United Kingdom
Primary
Concomitant
Melaena Hospitalization 1/13/2008 Male 3/12/2008 Physician France
Primary
Secondary
Concomitant
Depression Hospitalization 2/7/2008 Male 3/12/2008 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/11/2007 Male 3/12/2008 Physician United Kingdom
Primary
Secondary
Anaphylactic Shock Other Serious 5/15/2008 Female 7/3/2008 Consumer Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 6/11/2008 51 Female 135 lb 7/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 6/19/2008 Female 108 lb 7/3/2008 Physician United Kingdom
Primary
Concomitant
Anaphylactic Shock Hospitalization Female 7/3/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 5/24/2008 Male 157 lb 7/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 59 Male 7/7/2008 Pharmacist Germany
Primary
Secondary
Pneumonia Hospitalization 2/29/2008 Male 7/8/2008 Physician Austria
Primary
Concomitant
Nausea Hospitalization 5/24/2008 Male 7/11/2008 Physician France
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 4/23/2008 Male 7/11/2008 Physician Austria
Primary
Concomitant
Skin Fissures Other Serious 5/15/2008 Male 7/14/2008 Physician Germany
Primary
Concomitant
Prothrombin Level Decreased Other Serious Female 7/14/2008 Physician United Kingdom
Primary
Concomitant
Hypoaesthesia Disability 11/22/2007 Female 98 lb 7/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 10/4/2005 Female 11/13/2008 Physician Italy
Primary
Secondary
Respiratory Failure Death 68 Male 12/30/2008 Other Health Professional Spain
Primary
Concomitant
Haemolysis Life Threatening 12/1/2008 Female 1/16/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/10/2009 Female 12/30/2009 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 7/25/2009 68 Male 132 lb 12/31/2009 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/12/2009 Male 298 lb 1/4/2010 Physician Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 2/3/2010 61 Male 155 lb 3/2/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 2/3/2010 61 Male 155 lb 3/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombosis Other Serious 50 Male 3/18/2010 Physician Japan
Primary
Concomitant
Tumour Perforation Hospitalization 9/16/2009 Female 132 lb 3/18/2010 Physician France
Primary
Concomitant
Urinary Tract Infection Other Serious 3/14/2010 75 Female 163 lb 5/10/2010 Physician Belgium
Primary
Secondary
Sepsis Death 1/15/2010 51 Male 5/10/2010 Physician United States
Primary
Secondary
Pulmonary Embolism Death 1/4/2010 63 Male 128 lb 5/12/2010 Physician Germany
Primary
Concomitant
Retroperitoneal Abscess Life Threatening 5/15/2008 66 Male 181 lb 5/11/2010 Physician Poland
Primary
Secondary
Pancreatitis Acute Hospitalization 11/2/2008 54 Female 150 lb 5/12/2010 Physician Russian Federation
Primary
Secondary
Neutropenia Hospitalization 1/1/2010 63 Male 154 lb 5/13/2010 Physician France
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/28/2009 71 Female 126 lb 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Autoimmune Thrombocytopenia Other Serious 3/9/2010 68 Male 212 lb 5/18/2010 Physician Germany
Primary
Secondary
Sepsis Death 1/15/2010 51 Male 5/18/2010 Physician United States
Primary
Secondary
Lividity Death 4/23/2010 34 Male 185 lb 5/21/2010 Consumer Poland
Primary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 5/28/2010 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/12/2010 66 Female 264 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2010 63 Male 154 lb 6/1/2010 Physician France
Primary
Secondary
Concomitant

Drug Data