Fluconazole combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 10/18/2004 54 9/16/2005 Pharmacist United States
Primary
Concomitant
Rash Pruritic Hospitalization 12/30/2005 Male 170 lb 2/9/2006 Pharmacist United States
Primary
Secondary
Palpable Purpura Hospitalization 1/25/2006 66 Male 161 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Skin Maceration Hospitalization 12/31/2005 89 Female 168 lb 2/23/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/5/2005 5/16/2006 Pharmacist United States
Primary
Concomitant
Infected Skin Ulcer Hospitalization 4/1/2006 59 Male 109 lb 5/23/2006 Physician United States
Primary
Concomitant
Urine Output Decreased Required Intervention 4/25/2006 61 Female 139 lb 7/5/2006 Physician United States
Primary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/20/2005 62 Male 8/11/2006 Pharmacist United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 9/14/2006 83 Male 222 lb 9/20/2006 Pharmacist United States
Primary
Secondary
Mental Status Changes Life Threatening 4/27/2006 Female 110 lb 10/5/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Life Threatening 6/8/2006 2 Female 10/11/2006 Consumer United States
Primary
Concomitant
Optic Ischaemic Neuropathy Hospitalization 8/1/2006 51 Male 10/9/2006 United Kingdom
Primary
Secondary
Concomitant
Optic Ischaemic Neuropathy Hospitalization 51 Male 10/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 62 Male 11/16/2006 Consumer Japan
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/21/2006
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/14/2006 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 1/19/2007 38 Female 220 lb 1/22/2007 Pharmacist United States
Primary
Secondary
Cerebral Infarction Disability 12/1/2006 72 Female 106 lb 3/13/2007 Physician Japan
Primary
Concomitant
Sensation Of Heaviness Hospitalization 3/1/2007 51 Male 3/16/2007 Physician United States
Primary
Secondary
Concomitant
Fluid Retention 1/11/2006 49 Female 320 lb 1/23/2007 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 3/1/2005 Male 172 lb 7/25/2007 Australia
Primary
Secondary
Concomitant
Tongue Haematoma Hospitalization 6/7/2006 68 Female 8/1/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 7/22/2007 53 Female 174 lb 8/3/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 8/3/2007 Finland
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 42 Male 9/6/2007 Other Health Professional Canada
Primary
Secondary
Rhabdomyolysis Other Serious 76 Male 9/1/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Other Serious 42 Male 9/15/2007 Canada
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 84 Female 10/16/2007
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 42 Male 10/19/2007 Canada
Primary
Secondary
Concomitant
Skin Infection Disability 10/2/2007 50 Male 11/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oral Pain Hospitalization 8/26/2007 80 Female 153 lb 12/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Oral Candidiasis 1/1/2004 76 Female 12/28/2007 Consumer United States
Primary
Concomitant
Self-medication Hospitalization 7/24/2007 41 Female 139 lb 11/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Required Intervention 11/8/2007 83 Male 2/27/2008 Pharmacist United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 10/11/2007 81 Female 3/3/2008 Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 66 Female 152 lb 3/11/2008 Pharmacist United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 2/29/2008 Female 2/29/2008 Pharmacist United States
Primary
Concomitant
Blood Potassium Increased Required Intervention 1/13/2008 41 Male 331 lb 2/20/2008 United States
Primary
Concomitant
Lipodystrophy Acquired Hospitalization 1/8/2008 Male 172 lb 5/2/2008 Physician Brazil
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 4/1/2008 49 Female 155 lb 5/9/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 10/1/2007 86 Female 5/10/2008 Pharmacist United States
Primary
Secondary
International Normalised Ratio Increased Life Threatening 7/15/2007 48 Female 6/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2007 71 Female 126 lb 6/23/2008 Physician Japan
Primary
Secondary
Concomitant
Syncope Required Intervention 11/8/2007 83 Male 11/10/2007 Pharmacist United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 6/14/2008 65 Female 6/19/2008 Pharmacist United States
Primary
Secondary
Urinary Retention Other Serious 1/4/2007 71 Female 126 lb 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
Lipohypertrophy Hospitalization 3/10/2008 Male 172 lb 7/21/2008 Physician Brazil
Primary
Secondary
Concomitant
Treatment Noncompliance Required Intervention 7/7/2008 60 Male 223 lb 7/20/2008 Pharmacist United States
Primary
Secondary
International Normalised Ratio Increased Other Serious 49 Male 8/6/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
International Normalised Ratio Increased Life Threatening 49 Male 150 lb 8/4/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 49 Male 8/11/2008 Other Health Professional Japan
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 8/10/2008 74 Female 146 lb 8/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 49 Male 9/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 6/4/2007 11/13/2008 Lawyer United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 6/4/2007 11/23/2008 Lawyer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 49 Male 8/7/2008 Japan
Primary
Secondary
Concomitant
Pain In Extremity Female 12/12/2008 United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Rash Generalised 6/2/2008 52 Female 2/4/2009 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/7/2008 38 Female 139 lb 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/7/2008 38 Female 139 lb 3/2/2009 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2/17/2009 76 Male 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2/17/2009 76 Male 3/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/7/2008 38 Female 139 lb 4/21/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 51 Male 5/12/2009
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/7/2008 38 Female 139 lb 5/12/2009 Physician United States
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 134 lb 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 134 lb 5/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 5/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/7/2008 38 Female 139 lb 7/16/2009 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 6/12/2009 85 Male 146 lb 7/20/2009 Pharmacist United States
Primary
Secondary
Wound Other Serious 1/1/2004 64 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Wound Other Serious 1/1/2004 64 Male 7/28/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2008 Female 7/28/2009 Pharmacist United States
Primary
Concomitant
Wound Other Serious 1/1/2004 64 Male 8/5/2009 Physician United States
Primary
Secondary
Concomitant
Wound Other Serious 1/1/2004 64 Male 8/5/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 7/31/2009 United States
Primary
Concomitant
Sepsis Other Serious 11/1/2007 63 Male 179 lb 8/28/2009 Pharmacist United States
Primary
Concomitant
Uterine Polyp Hospitalization 61 Female 8/25/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2004 Female 183 lb 9/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/1/2009 United States
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2008 Female 9/8/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/3/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 11/15/2008 70 Male 202 lb 11/18/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 9/17/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2006 Female 10/12/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 6/25/2007 69 Female 10/9/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 10/16/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 61 Female 10/17/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Subdural Haematoma Other Serious 11/3/2009 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 6/25/2007 64 Female 10/26/2009 United States
Primary
Concomitant
Tremor Hospitalization 11/1/2001 27 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/9/2009 United States
Primary
Concomitant
Respiratory Failure Other Serious 7/29/2005 77 Male 225 lb 11/24/2009 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 12/1/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Scar Other Serious 8/1/2004 Male 12/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 50 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Pain Other Serious 6/19/2007 60 Male 12/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 1/18/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 2/4/2009 63 Female 240 lb 1/23/2010 Pharmacist United States
Primary
Secondary
Lower Gastrointestinal Haemorrhage Required Intervention 10/18/2009 88 Male 1/27/2010 Pharmacist United States
Primary
Secondary
Tooth Extraction Other Serious 1/1/2006 Female 1/30/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 50 Male 1/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 2/11/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 2/24/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 3/1/2009 Female 2/26/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/2/2004 Male 215 lb 2/26/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 50 Male 2/18/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2008 75 Female 198 lb 3/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 3/4/2010 Lawyer United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2006 Female 3/8/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 11/29/2007 Female 3/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/18/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 3/22/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 3/22/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/30/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 3/31/2010 Other Health Professional United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/22/2008 64 Male 4/5/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/1/2010 68 Female 4/9/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 11/29/2007 55 Female 4/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2005 64 Female 4/14/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 4/22/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/1/2008 68 Female 4/26/2010 Lawyer United States
Primary
Concomitant
Synovial Cyst Hospitalization 2/3/2010 68 Female 4/26/2010 Physician United States
Primary
Secondary
Concomitant
Synovial Cyst Hospitalization 2/1/2010 68 Female 4/28/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 39 NotSpecified 4/19/2010 Lawyer United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant

Drug Data