Fluconazole combined with Voriconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Life Threatening 12/6/2005 55 Male 168 lb 12/14/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 1/6/2006 41 Female 152 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Death 17 Female 1/23/2006 Physician United States
Primary
Secondary
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tracheostomy Hospitalization 40 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 2/8/2005 18 Female 128 lb 1/10/2006 Physician United States
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Systemic Mycosis Life Threatening 4/1/2006 49 Female 5/25/2006 Physician Austria
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 4/1/2004 29 Female 6/1/2006 Pharmacist United States
Primary
Secondary
Pyrexia Other Serious 8 Female 6/2/2006 Japan
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 5/24/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/8/2006 73 Male 7/11/2006 Japan
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 7/18/2006 Japan
Primary
Concomitant
Pyrexia Hospitalization 5/3/2006 56 Male 220 lb 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 9/10/2006 47 Female 266 lb 9/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 8/1/2004 10 Female 10/19/2006 Germany
Primary
Concomitant
Drug Ineffective Hospitalization 50 Male 1/9/2007 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 50 Male 1/25/2007 Physician United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 12/13/2006 49 Female 1/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/13/2006 49 Female 1/27/2007 Physician United States
Primary
Secondary
Concomitant
Vessel Puncture Site Haematoma Other Serious 12/13/2006 49 Female 1/31/2007 Physician United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 2/5/2007 Germany
Primary
Secondary
Sensation Of Heaviness Hospitalization 3/1/2007 51 Male 3/16/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8 Female 3/20/2007 Japan
Primary
Concomitant
Pyrexia Hospitalization 2/8/2007 60 Female 126 lb 3/27/2007 Other Health Professional France
Primary
Concomitant
Rash Other Serious 4/6/2007 Physician Brazil
Primary
Secondary
Ventricular Dysfunction Other Serious 3/28/2006 7 Male 4/12/2007 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 11/1/2005 31 Female 4/30/2007 Physician Belgium
Primary
Concomitant
Septic Shock Other Serious 11/1/2005 31 Female 5/2/2007 Physician Belgium
Primary
Concomitant
Treatment Failure Death 57 Female 5/11/2007 Other Health Professional United States
Primary
Concomitant
Septic Shock Other Serious 11/1/2005 31 Female 5/21/2007 Physician Belgium
Primary
Secondary
Concomitant
Venous Occlusion Hospitalization 5/21/2007 Male 26 lb 5/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Failure Life Threatening 57 Female 6/25/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 4/22/2007 Female 158 lb 7/11/2007 Physician United States
Primary
Secondary
Concomitant
Systemic Mycosis Life Threatening 4/1/2006 49 Female 99 lb 7/13/2007 Physician Austria
Primary
Concomitant
Staphylococcal Infection Other Serious 53 Male 7/26/2007 Switzerland
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Venous Occlusion Hospitalization 52 Female 9/28/2007 United States
Primary
Concomitant
Multi-organ Failure Hospitalization 63 Female 9/28/2007 United States
Primary
Concomitant
Multi-organ Failure Hospitalization 30 Male 9/28/2007 United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2004 Female 10/22/2007 Physician United States
Primary
Secondary
Pericarditis Fungal Other Serious 11/11/2005 3 Female 10/23/2007
Primary
Secondary
Concomitant
Peritonitis Death Female 10/29/2007
Primary
Secondary
Drug Resistance Other Serious 45 Female 11/6/2007 United States
Primary
Secondary
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/23/2007 Male 139 lb 11/7/2007 United States
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/23/2007 Male 139 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 1/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 52 Male 1/16/2008
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 1/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 36 Female 3/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 17 Male 3/28/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 4/4/2008 Ireland
Primary
Concomitant
Squamous Cell Carcinoma Other Serious Male 5/9/2008 France
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 53 Female 6/19/2008 Other Health Professional Japan
Primary
Secondary
Sepsis Other Serious 45 Male 95 lb 7/11/2008 Other Health Professional Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 45 Male 95 lb 7/25/2008 Other Health Professional Japan
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/28/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/30/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/1/2008 Poland
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 53 Female 8/18/2008 Other Health Professional Japan
Primary
Secondary
Metabolic Acidosis Life Threatening 7/31/2008 Female 8/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/22/2008 Poland
Primary
Concomitant
Pneumonia Life Threatening 7/31/2008 Female 8/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 9/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Bradycardia Life Threatening 3/30/2008 63 Female 9/5/2008 Other Health Professional France
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Life Threatening 4/2/2008 63 Female 9/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Life Threatening 7/31/2008 Female 9/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 10/28/2007 Female 143 lb 9/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 9/25/2008 Ireland
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 10/16/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Drug Resistance Other Serious 40 Male 10/20/2008 Other Health Professional Czech Republic
Primary
Secondary
Drug Resistance Other Serious 55 Male 10/21/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 10/22/2008 Other Health Professional United States
Primary
Concomitant
Drug Resistance Hospitalization 40 Male 10/22/2008 Other Health Professional Czech Republic
Primary
Secondary
Fungal Endocarditis Other Serious 40 Male 11/4/2008 Czech Republic
Primary
Secondary
Drug Interaction Other Serious 65 Male 11/4/2008 Italy
Primary
Concomitant
Interacting
Vomiting Other Serious 5/19/2008 Male 52 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Systemic Candida Other Serious 32 Male 12/1/2008
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 12/1/2008 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 65 Male 12/18/2008
Primary
Secondary
Pyrexia Hospitalization 24 Male 12/18/2008
Primary
Secondary
Concomitant
Death Death 5/28/2008 12/22/2008 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Sudden Death Death 5/28/2008 12/24/2008 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 Female 93 lb 1/5/2009 Physician Thailand
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 12/9/2008 Male 96 lb 1/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/9/2007 1/16/2009 Physician Singapore
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 1/21/2009 Physician Thailand
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/9/2007 1/26/2009 Physician Singapore
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 3/4/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Unknown 3/3/2009 Germany
Primary
Secondary
Concomitant
Splenomegaly Other Serious 24 163 lb 3/17/2009 Consumer Germany
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 163 lb 4/10/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 163 lb 4/15/2009
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious Male 4/27/2009 Other Health Professional France
Primary
Concomitant
Graft Versus Host Disease Death 7/5/2008 71 Male 157 lb 5/1/2009 Physician Belgium
Primary
Concomitant
Vomiting Hospitalization 3/4/2008 5/4/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 4/12/2005 Male 131 lb 5/26/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/4/2008 34 5/26/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/4/2008 34 5/26/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Viral Infection Death 1/1/2008 67 Male 143 lb 5/29/2009 Physician Belgium
Primary
Concomitant
Respiratory Failure Other Serious 11/9/2007 57 6/5/2009 Physician Singapore
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 6/24/2009 United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 6/25/2009 United States
Primary
Secondary
Concomitant
Sinusitis Aspergillus Other Serious 3 Female 7/2/2009
Primary
Secondary
Sudden Death Other Serious 7/6/2009 Other Health Professional United States
Primary
Concomitant
Viral Infection Life Threatening 1/1/2009 21 Female 148 lb 7/7/2009 Physician Belgium
Primary
Concomitant
Somnolence Hospitalization 8/11/2009 Male 39 lb 8/18/2009 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2009 Male 8/31/2009 Netherlands
Primary
Concomitant
Somnolence Hospitalization 8/11/2009 Male 39 lb 8/24/2009 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 8/11/2009 Male 39 lb 9/16/2009 United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 24 Male 11/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 12/9/2008 Male 96 lb 12/16/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 9/22/2006 37 Male 1/4/2010 Consumer Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/14/2009 56 Female 136 lb 1/21/2010 United States
Primary
Secondary
Concomitant
Pneumonia Death 1/28/2009 54 Female 110 lb 1/27/2010 Physician Korea, Republic Of
Primary
Concomitant
Organ Failure Death 6/1/2009 63 Female 119 lb 2/12/2010 Physician Belgium
Primary
Concomitant
Treatment Failure Other Serious 44 2/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pseudoporphyria Other Serious 4/1/2005 55 Female 143 lb 2/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 6/2/2004 Male 215 lb 3/11/2010 Other Health Professional United States
Primary
Concomitant
Treatment Failure Other Serious 44 3/12/2010 Other Health Professional Canada
Primary
Concomitant
Transaminases Increased Other Serious 3/17/2010 United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 3/19/2010 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 9/19/2009 17 Male 198 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Thrombocytopenia Other Serious 12/29/2009 75 Male 4/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suprapubic Pain Hospitalization 4/23/2007 9 Female 54 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Failure Other Serious 44 4/23/2010 Other Health Professional Canada
Primary
Concomitant
Platelet Count Decreased Other Serious 4/1/2010 39 Female 139 lb 5/4/2010 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Death Female 5/6/2010 Other Health Professional France
Primary
Secondary
Concomitant
Multiple-drug Resistance Death 9 Female 5/6/2010 France
Primary
Secondary
Concomitant
Drug Resistance Death 9 Female 5/14/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hypopyon Other Serious 43 Male 6/19/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4/1/2010 39 Female 139 lb 7/16/2010 Pharmacist United States
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 9/19/2009 17 Male 198 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Vomiting Other Serious 43 Male 104 lb 7/20/2010 Taiwan, Province Of China
Primary
Secondary
Concomitant
Bradycardia Death 7/22/2010 68 Female 143 lb 7/29/2010 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data