Fluconazole combined with Ursodiol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transaminases Increased Hospitalization 11/1/2005 75 Male 198 lb 1/9/2006 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 2/8/2006 Male 190 lb 2/23/2006 Pharmacist United States
Primary
Concomitant
Myopathy Steroid Hospitalization 10/28/2005 40 Female 154 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Death 11/17/2004 27 Female 6/1/2006 Belgium
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Skin Lesion Other Serious 0 Male 2/15/2007 Other Health Professional Turkey
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 12/28/2006 50 Female 110 lb 2/8/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 164 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/9/2007 19 Male 167 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Bradycardia Required Intervention 2/24/2006 Female 213 lb 7/31/2007 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/11/2007 Male 243 lb 9/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/24/2007 51 Male 9/24/2007 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/24/2007 51 Male 11/2/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/24/2007 51 Male 12/13/2007 United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 1/21/2008 Female 21 lb 1/23/2008 United States
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2008 Female 21 lb 1/28/2008 Canada
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2008 Female 21 lb 2/8/2008 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 12/24/2007 41 Female 168 lb 3/12/2008 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 3/3/2008 Female 148 lb 5/28/2008 Physician Belgium
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/3/2007 54 Male 6/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 5/12/2008 60 Female 200 lb 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 3/3/2008 Female 148 lb 7/10/2008 Physician Belgium
Primary
Concomitant
Weight Decreased Other Serious 6/1/2007 Female 88 lb 7/10/2008 Physician United States
Primary
Concomitant
Stem Cell Transplant Hospitalization 5/12/2008 60 Female 200 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 30 Male 7/14/2008 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/27/2008 21 Male 7/11/2008 Physician France
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 1/6/2008 Male 29 lb 7/24/2008 Other Health Professional Brazil
Primary
Concomitant
Visual Impairment Hospitalization 8/22/2007 Male 97 lb 7/24/2008 Other Health Professional Brazil
Primary
Concomitant
Eye Disorder Other Serious 34 Male 7/25/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/12/2008 Male 52 lb 7/28/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Disability 6/4/2008 Female 114 lb 7/28/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Disability 5/28/2008 7/31/2008 Other Health Professional Brazil
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 8/11/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 1/6/2008 Male 29 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Other Serious 1/12/2008 Male 52 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 10/10/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 10/16/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Shock Other Serious 11/30/2007 Male 35 lb 11/3/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/12/2007 19 Male 165 lb 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 11/25/2008 36 Female 105 lb 12/6/2008 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Other Serious 2/4/2008 Female 12/10/2008 Other Health Professional Canada
Primary
Concomitant
Pancreatitis Acute Other Serious 2/4/2008 Female 12/10/2008 Other Health Professional Canada
Primary
Concomitant
Weight Increased Hospitalization 5/1/2008 68 Female 122 lb 12/26/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/3/2009 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 Female 116 lb 3/3/2009 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/5/2009 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 57 Female 116 lb 3/26/2009 United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/21/2008 Male 4/16/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 76 Female 9/25/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Acute Myeloid Leukaemia Death 9/30/2009 Female 114 lb 11/19/2009 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 8/16/2009 64 Male 11/23/2009 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 8/16/2009 64 Male 12/21/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization Male 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/19/2009 61 Female 182 lb 2/10/2010 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2003 42 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 5/20/2010 United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2008 62 Male 6/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/19/2009 54 Male 132 lb 6/21/2010 Other Health Professional Japan
Primary
Concomitant
Streptococcal Sepsis Hospitalization 64 Female 6/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 7/1/2010 United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 12/22/2008 46 Male 7/15/2010 Physician Japan
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 12/22/2008 46 Male 7/27/2010 Physician Japan
Primary
Concomitant
Respiratory Distress Hospitalization 5/3/2010 2 Male 8/16/2010 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious 11/25/2008 36 Female 105 lb 8/10/2010 United States
Primary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 9/13/2010 United States
Primary
Concomitant
Encephalitis Herpes Hospitalization 9/27/2009 74 Male 10/4/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 223 lb 10/28/2010 United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2010 17 Female 83 lb 10/4/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 223 lb 12/29/2010 United States
Primary
Concomitant
Respiratory Failure Death 1/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/28/2010 30 Female 99 lb 1/6/2011 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 12/1/2010 74 Female 101 lb 2/3/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 8/13/2010 77 Male 194 lb 2/8/2011 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Life Threatening 3/5/2010 2/9/2011 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 12/17/2010 74 Female 101 lb 2/10/2011 Physician Japan
Primary
Concomitant
Hepatosplenomegaly Death 1/27/2011 68 Male 2/15/2011 Other Health Professional United States
Primary
Concomitant
Somnolence Death 8/13/2010 77 Male 194 lb 3/3/2011 Physician United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Death 10/14/2010 49 Male 2/23/2011 Physician United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 3/12/2010 2 Male 22 lb 3/9/2011 Physician Japan
Primary
Concomitant
Abdominal Distension Other Serious 10/7/2010 49 Male 3/10/2011 Other Health Professional United States
Primary
Concomitant
Bacterial Test Positive Other Serious 11/20/2010 57 Female 3/11/2011 Other Health Professional United States
Primary
Concomitant
Nephropathy Hospitalization 3/17/2011 2 Female 32 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Atelectasis Hospitalization 3/17/2011 2 Female 32 lb 3/23/2011 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 12/17/2010 74 Female 101 lb 4/7/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 6/16/2010 53 Male 154 lb 4/8/2011 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Platelet Count Abnormal Other Serious 1/1/2008 62 Male 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophagia Hospitalization 4/9/2011 69 Male 4/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/9/2011 69 Male 4/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 4/9/2011 69 Male 5/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/16/2011 Physician Serbia
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/16/2011 Physician Serbia
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 4/9/2011 69 Male 5/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Culture Positive Hospitalization 4/9/2011 69 Male 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 2/14/2011 54 Female 6/7/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Other Serious 12/17/2010 74 Female 101 lb 6/8/2011 Physician Japan
Primary
Concomitant
Hypophagia Hospitalization 4/9/2011 69 Male 6/9/2011 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 7/18/2010 61 Female 110 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Death 7/28/2010 30 Female 99 lb 6/22/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Hospitalization 5/25/2010 23 Female 73 lb 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 3/5/2010 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Female 7/5/2011 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/7/2010 49 Male 6/29/2011 Other Health Professional United States
Primary
Concomitant
Pulseless Electrical Activity Death 1/25/2011 66 Male 6/30/2011 Other Health Professional United States
Primary
Concomitant
Pruritus 7/12/2011 16 Female 7/20/2011 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/17/2010 57 Female 7/21/2011 Other Health Professional United States
Primary
Concomitant
Joint Range Of Motion Decreased Other Serious 6/6/2011 36 Male 145 lb 6/13/2011 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/10/2010 49 Female 97 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 11/10/2010 49 Female 97 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 1/17/2011 27 Female 95 lb 8/5/2011 Physician Japan
Primary
Concomitant
Insomnia Other Serious 11/23/2010 62 Female 108 lb 8/8/2011 Physician Japan
Primary
Concomitant

Drug Data