Fluconazole combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2003 38 Female 2/13/2006 Physician Germany
Primary
Secondary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/1/2005 Male 154 lb 3/31/2006 Physician Germany
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 12/5/2005 55 Male 4/6/2006 Other Health Professional France
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 12/5/2005 55 Male 4/10/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 4/25/2006 United States
Primary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 7/6/2006 United States
Primary
Concomitant
Pyrexia Other Serious 6/28/2006 68 Male 7/17/2006 Physician Spain
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 68 Male 8/4/2006 Physician Spain
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/6/2004 Female 8/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 3/1/2005 63 Female 8/17/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 68 Male 8/24/2006 Physician Spain
Primary
Concomitant
Renal Failure Hospitalization 6/5/2005 75 Female 174 lb 9/14/2006 Physician Poland
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/5/2005 75 Female 174 lb 9/14/2006 Physician Poland
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/29/2006 64 Female 11/1/2006 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/6/2004 Female 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Life Threatening 9/4/2006 Female 12/19/2006 Physician
Primary
Secondary
Concomitant
Rash Other Serious 8/1/2006 Female 121 lb 12/21/2006 Physician Hungary
Primary
Concomitant
Rash Other Serious 8/16/2006 Female 121 lb 1/19/2007 Physician Hungary
Primary
Concomitant
Localised Infection Other Serious 4/1/2006 57 Male 255 lb 1/30/2007 United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 3/28/2006 7 Male 4/12/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatitis C Other Serious 2/7/2002 Male 209 lb 8/16/2007 Consumer Japan
Primary
Concomitant
Hepatotoxicity Other Serious 38 Female 8/3/2007 Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious Female 9/1/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 2/10/2004 Male 9/28/2007 Physician France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 84 Female 10/16/2007
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Confusional State Hospitalization 10/25/2007 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/13/2007 83 Female 104 lb 12/19/2007 Physician Japan
Primary
Secondary
Oral Candidiasis 1/1/2004 76 Female 12/28/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Venoocclusive Disease Hospitalization 2 Male 3/31/2008
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 4/16/2008 Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Lipodystrophy Acquired Hospitalization 1/8/2008 Male 172 lb 5/2/2008 Physician Brazil
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 5/9/2008 Germany
Primary
Concomitant
Septic Shock Hospitalization 12/1/2007 Male 124 lb 5/20/2008 Belgium
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/26/2008 53 Female 5/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Temperature Intolerance Hospitalization 6/9/2008 Male 249 lb 6/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/22/2008 Male 249 lb 6/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/22/2008 65 Male 249 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Bacterial Hospitalization 6/9/2008 65 Male 243 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Lipohypertrophy Hospitalization 3/10/2008 Male 172 lb 7/21/2008 Physician Brazil
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Death 9/28/2007 Male 141 lb 8/13/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 7/13/2007 83 Female 104 lb 11/26/2008 Physician Japan
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 9/12/2008 66 Female 12/5/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Other Serious 1/1/1991 45 Female 270 lb 2/12/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 60 Female 135 lb 4/3/2009 United States
Primary
Concomitant
Septic Shock Hospitalization 12/1/2007 4/20/2009 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/30/2009 75 Male 5/15/2009 Physician Japan
Primary
Secondary
Concomitant
Performance Status Decreased Life Threatening 6/4/2009 47 Male 6/25/2009 Physician Poland
Primary
Secondary
Concomitant
Performance Status Decreased Life Threatening 6/4/2009 47 Male 7/9/2009 Physician Poland
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 5/28/2009 Male 7/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Swelling Hospitalization 72 Female 7/27/2009 United States
Primary
Concomitant
Wound Complication Hospitalization 10/22/2005 Male 284 lb 8/11/2009 Other Health Professional United States
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 10/22/2005 Male 284 lb 8/18/2009 Other Health Professional United States
Primary
Concomitant
Obsessive-compulsive Disorder Male 40 lb 8/25/2009 Consumer
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 6/17/2009 68 Female 8/26/2009 Physician Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/22/2008 69 Male 8/27/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11/1/2007 63 Male 179 lb 8/28/2009 Pharmacist United States
Primary
Concomitant
Torsade De Pointes Life Threatening 6/17/2009 Female 9/2/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 51 Female 159 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Sinus Arrest Hospitalization 8/23/2009 Male 97 lb 9/4/2009 Consumer United States
Primary
Secondary
Concomitant
Metastases To Peritoneum Life Threatening 6/4/2009 47 Male 9/4/2009 Physician Poland
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 10/22/2005 Male 285 lb 9/17/2009 Other Health Professional United States
Primary
Concomitant
Tinnitus 1/1/1998 64 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Hyperglycaemia Other Serious 10/27/2006 56 Female 183 lb 9/23/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 9/29/2009 United States
Primary
Concomitant
Surgery Hospitalization 72 Female 9/25/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 60 Female 9/29/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Nervous System Disorder Other Serious 7/22/2008 69 Male 10/6/2009 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/1/2007 47 10/8/2009 Physician Belgium
Primary
Concomitant
Sinus Arrest Hospitalization 8/23/2009 Male 97 lb 10/12/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2009 68 Female 104 lb 10/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 72 Female 10/22/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 72 Female 10/26/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 72 Female 11/4/2009 Lawyer United States
Primary
Concomitant
Sinus Congestion 6/15/2009 12/9/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2009 68 Female 104 lb 12/15/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 12/22/2009 Pharmacist Spain
Primary
Concomitant
Sedation Life Threatening 10/5/2009 Male 159 lb 10/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/1/2007 47 Male 124 lb 1/9/2010 Physician Belgium
Primary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Vomiting Hospitalization 60 Female 1/22/2010 United States
Primary
Concomitant
Wheezing Hospitalization 1/1/2006 61 Female 170 lb 2/10/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Male 980 lb 2/23/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 Male 980 lb 3/1/2010 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2008 69 Male 3/19/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/30/2009 75 Male 4/12/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2008 69 Male 4/19/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2009 68 Female 104 lb 4/19/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/24/2008 69 Male 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 2/6/2008 76 Male 195 lb 4/23/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/5/2009 4/29/2010 Physician Netherlands
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 86 Male 161 lb 5/5/2010 Pharmacist Taiwan, Province Of China
Primary
Concomitant
Thrombocytopenia Other Serious 10/5/2009 5/11/2010 Physician Netherlands
Primary
Concomitant
Vomiting Other Serious 2/1/2008 51 Female 159 lb 5/14/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 6/1/2008 48 Female 7/22/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 1/1/2008 44 Female 8/3/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/15/2010 32 Female 212 lb 7/30/2010 United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/1/2007 47 Male 124 lb 8/4/2010 Physician Belgium
Primary
Concomitant
Encephalopathy Other Serious 8/1/2009 61 Male 8/23/2010 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 6/15/2010 62 Male 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Ileus Hospitalization Female 232 lb 8/23/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 6/25/2010 55 Male 157 lb 8/24/2010 Sweden
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2009 68 Female 104 lb 8/30/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 51 Female 159 lb 9/8/2010 Other Health Professional United States
Primary
Concomitant
Hiv Infection Other Serious 12/21/2005 37 Female 96 lb 9/16/2010 Physician Thailand
Primary
Concomitant
Type 2 Diabetes Mellitus 10/27/2006 56 Female 786 lb 9/20/2010 United States
Primary
Concomitant
Ileus Hospitalization Female 232 lb 10/1/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 12 Female 66 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Bradycardia Other Serious 10/13/2010 Female 5 lb 11/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Bradycardia Other Serious 10/13/2010 11/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Bradycardia Required Intervention 10/13/2010 Female 5 lb 10/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Bradycardia Neonatal Other Serious 10/13/2010 Female 5 lb 10/26/2010 United Kingdom
Primary
Concomitant
Uterine Cancer Hospitalization Female 12/2/2010 Physician Netherlands
Primary
Concomitant
Ventricular Tachycardia Life Threatening 12/11/2010 0 Male 5 lb 12/13/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2008 41 Female 145 lb 12/6/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Fungal Hospitalization 7/26/2010 51 Male 198 lb 1/3/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 2/6/2008 76 Male 195 lb 1/18/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haematochezia Other Serious Male 8 lb 2/11/2011 Consumer United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 2/18/2011 Other Health Professional Germany
Primary
Concomitant
Leukaemia Plasmacytic Death 11/30/2010 58 Female 2/28/2011 Physician United States
Primary
Concomitant
Ileus Hospitalization 6/4/2009 47 Male 2/23/2011 Physician Poland
Primary
Secondary
Concomitant
Ileus Death 6/4/2009 47 Male 3/3/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Throat Irritation Other Serious 3/18/2011 Other Health Professional Germany
Primary
Concomitant
Pulmonary Arterial Hypertension Death 3/8/2011 76 Female 3/29/2011 Other Health Professional United States
Primary
Concomitant
Emotional Distress Hospitalization 1/31/2004 43 Female 3/31/2011 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 4/5/2011 Physician United States
Primary
Concomitant
Tendon Rupture 1/23/2011 83 Male 200 lb 3/30/2011 Pharmacist United States
Primary
Concomitant
Atelectasis Hospitalization 3/17/2011 2 Female 32 lb 3/23/2011 United States
Primary
Secondary
Concomitant
Gallbladder Disorder Hospitalization 5/9/2009 36 Female 120 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data