Fluconazole combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2005 59 Male 198 lb 1/24/2006 Pharmacist Spain
Primary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 10/19/2005 0 Male 3/6/2006 Germany
Primary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 3/28/2006 France
Primary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 4/13/2006 France
Primary
Concomitant
Stomatitis Hospitalization 3/27/2006 Male 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 58 Female 5/23/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2006 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/3/2006 Male 152 lb 11/1/2006
Primary
Concomitant
Sudden Death Death 4/2/2006 24 Male 216 lb 11/9/2006 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Death 79 Male 231 lb 1/10/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/13/2003 Male 1/26/2007 Australia
Primary
Secondary
Concomitant
Cardiac Arrest Death 4/2/2006 Male 216 lb 1/31/2007 Physician United States
Primary
Concomitant
Hypoglycaemia Death 79 Male 231 lb 2/6/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Death 1/13/2007 Male 121 lb 2/21/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Neonatal Hospitalization 7/3/2006 0 Female 2/26/2007 Belgium
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/18/2007 Male 214 lb 3/30/2007 Australia
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/17/2007 Male 214 lb 4/5/2007 Australia
Primary
Secondary
Concomitant
Band Neutrophil Count Increased Hospitalization 2/6/2007 Male 99 lb 4/30/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
No Adverse Reaction 4/13/2003 Male 11/30/2007 Australia
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/19/2008 Male 133 lb 1/29/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 4/9/2008 France
Primary
Concomitant
Ventricular Tachycardia Other Serious 11 Male 5/13/2008
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2007 71 Female 126 lb 6/23/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/4/2007 71 Female 126 lb 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/19/2008 0 Male 7/10/2008 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Death 4/22/2008 0 Male 7/10/2008 Pharmacist United States
Primary
Concomitant
Status Epilepticus Death 4/24/2008 1 Female 7/24/2008 Other Health Professional United States
Primary
Concomitant
Status Epilepticus Death 4/24/2008 1 Female 7/24/2008 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Other Serious 9/22/2005 19 Male 179 lb 9/26/2008 Physician United States
Primary
Concomitant
Transplant Rejection Hospitalization 4/25/2006 10 Female 9/29/2008 Physician United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 9/23/1997 38 Female 203 lb 10/3/2008 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Respiratory Failure Death 11/5/2008 Female 1 lb 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/22/2005 19 Male 179 lb 12/30/2008 Physician United States
Primary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 12/21/2008 4 Male 44 lb 1/7/2009 Physician Germany
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/21/2008 4 Male 44 lb 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 4/25/2006 10 Female 2/18/2009 Physician United States
Primary
Concomitant
Transmission Of An Infectious Agent Via A Medicinal Product Hospitalization 1/1/2005 87 Female 5/27/2009 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 87 Female 6/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 87 Female 6/8/2009
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 87 Female 6/10/2009 United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 6/26/2009 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Wound Infection Fungal Death 10/21/2009 Male 110 lb 12/18/2009 Physician Hong Kong
Primary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 4/25/2006 10 Female 66 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 2/26/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Convulsion Hospitalization 3/5/2010 Male 3/18/2010 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 1/31/2010 55 Male 4/20/2010 Pharmacist Canada
Primary
Concomitant
Septic Shock Other Serious 1/1/2008 68 Female 4/26/2010 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 1/31/2010 55 Male 5/5/2010 Pharmacist Canada
Primary
Concomitant
Tachycardia Other Serious 1/8/2008 68 Female 190 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Convulsion Hospitalization 3/5/2010 2 Male 7/9/2010 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Life Threatening 8/4/2010 60 Female 97 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2010 61 Female 9/27/2010 Other Health Professional Netherlands
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 8/17/2010 77 Male 9/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 2/1/2007 68 Female 117 lb 10/1/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Leukopenia Life Threatening 8/4/2010 60 Female 97 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 10/21/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 12 Female 66 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 8/19/2010 77 Male 11/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Death 11/1/2010 67 Female 11/25/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 50 Male 262 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 11/11/2009 72 Female 126 lb 12/27/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 12/18/2010 55 Female 164 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Urinary Incontinence Hospitalization 4/26/2008 85 Female 100 lb 1/13/2011 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 12/1/2010 74 Female 101 lb 2/3/2011 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 12/17/2010 74 Female 101 lb 2/10/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 6/1/2010 45 Female 185 lb 2/16/2011 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Death 1/1/2010 61 Female 3/11/2011 Physician Netherlands
Primary
Secondary
Concomitant
Emotional Distress Hospitalization 1/31/2004 43 Female 3/31/2011 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Death 12/17/2010 74 Female 101 lb 4/7/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 6/16/2010 53 Male 154 lb 4/8/2011 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 2/24/2011 23 Female 165 lb 4/14/2011 Physician United States
Primary
Secondary
Concomitant
Confusional State Other Serious 11/1/2007 58 Male 137 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Aspergillosis Hospitalization 4/13/2011 14 Male 104 lb 4/21/2011 Physician
Primary
Concomitant
Delirium Hospitalization 85 Female 4/18/2011 United Kingdom
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious 2/24/2011 23 Female 165 lb 4/28/2011 Physician United States
Primary
Secondary
Concomitant
Walking Disability Other Serious 3/1/2007 55 Female 190 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Aspergillosis Hospitalization 4/13/2011 14 Male 104 lb 5/18/2011 Physician Korea, Republic Of
Primary
Concomitant
Decreased Appetite Other Serious 12/17/2010 74 Female 101 lb 6/8/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Hospitalization 12/20/2010 60 Female 6/10/2011 Physician Japan
Primary
Concomitant
Dehydration Hospitalization 4/7/2010 61 Female 6/10/2011 Physician Netherlands
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 6/13/2011 71 Male 211 lb 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 4/10/2011 27 Female 74 lb 6/29/2011 Pharmacist United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Cryptococcosis Other Serious 9/10/2008 58 Female 134 lb 8/5/2011 Physician Japan
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 8/5/2011 Female 9 lb 8/9/2011 Pharmacist United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 12/17/2010 74 Female 101 lb 8/11/2011 Physician Japan
Primary
Concomitant
Acute Left Ventricular Failure Hospitalization 3/4/2011 80 Female 8/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Death 6/13/2011 71 Male 211 lb 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/13/2011 71 Male 211 lb 8/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 1/1/2006 25 Female 140 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 4/1/2010 57 Male 144 lb 9/29/2011 Lawyer United States
Primary
Concomitant
Hypertension Other Serious 6/12/2010 53 Male 154 lb 10/5/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Acute Left Ventricular Failure Life Threatening 3/4/2011 80 Female 11/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Klebsiella Test Positive Death 10/21/2009 78 Male 110 lb 11/28/2011 Physician Hong Kong
Primary
Concomitant
Lymphocyte Count Decreased Hospitalization 8/4/2011 70 Female 11/29/2011 Other Health Professional Japan
Primary
Concomitant
Mantle Cell Lymphoma Death 12/17/2010 74 Female 101 lb 12/8/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/25/2010 11 Male 66 lb 12/12/2011 Physician Japan
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2010 65 Male 174 lb 12/15/2011 Consumer United States
Primary
Concomitant

Drug Data