Fluconazole combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 57 Male 1/4/2006 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/9/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/9/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 11/3/2005 35 Male 170 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2006 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 2/28/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 1/17/2006 34 Female 110 lb 2/8/2006 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/8/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Unknown 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/10/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 6/6/2006 Female 151 lb 7/4/2006 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Required Intervention 4/25/2006 61 Female 139 lb 7/5/2006 Physician United States
Primary
Concomitant
Pyrexia Other Serious 6/28/2006 68 Male 7/17/2006 Physician Spain
Primary
Concomitant
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 68 Male 8/4/2006 Physician Spain
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 68 Male 8/24/2006 Physician Spain
Primary
Concomitant
Liver Function Test Abnormal Disability 8/24/2006 79 Male 121 lb 10/9/2006 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Disability 8/24/2006 79 Male 121 lb 10/11/2006 Consumer United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Other Serious 11/1/2006 44 Male 11/13/2006 Pharmacist United States
Primary
Concomitant
Vocal Cord Disorder Life Threatening 11/11/2006 53 Male 11/30/2006 Pharmacist United States
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/13/2007 Physician Norway
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/30/2007 Physician Norway
Primary
Secondary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/19/2008 Male 133 lb 1/29/2008 United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 7/28/1997 65 Female 3/6/2008 Belgium
Primary
Concomitant
Interacting
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/28/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/30/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/1/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/22/2008 Poland
Primary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 10/10/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 12/1/2008 54 Male 268 lb 2/18/2009 United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Skin Laceration Other Serious 1/1/2003 40 Female 150 lb 4/14/2009 United States
Primary
Concomitant
Intraventricular Haemorrhage Death 2/22/2009 58 Male 187 lb 4/29/2009 Physician Spain
Primary
Concomitant
Seroma Hospitalization 5/11/2009 13 Male 145 lb 6/26/2009 Physician United States
Primary
Concomitant
Multi-organ Failure Other Serious 4/28/2009 72 Male 198 lb 8/3/2009 Other Health Professional Switzerland
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Diabetic Coma Other Serious 5/6/2007 52 Female 122 lb 9/23/2009 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Sinus Arrest Death 9/20/2009 33 Female 10/21/2009 Consumer Norway
Primary
Concomitant
Sinus Arrest Death 9/20/2009 33 Female 10/27/2009 Consumer Norway
Primary
Concomitant
Sinus Arrest Other Serious 9/20/2009 33 Female 10/28/2009 Physician Norway
Primary
Concomitant
Intraventricular Haemorrhage Death 2/22/2009 58 Male 187 lb 12/1/2009 Physician Spain
Primary
Concomitant
Wound Infection Fungal Death 10/21/2009 Male 110 lb 12/18/2009 Physician Hong Kong
Primary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 12/22/2009 Pharmacist Spain
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/19/2009 73 Female 12/28/2009 Physician Norway
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 10/4/2009 11 Female 81 lb 12/22/2009 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Screaming Hospitalization 10/4/2009 11 Female 81 lb 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/4/2008 Male 2/16/2010 Other Health Professional Germany
Primary
Secondary
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 2/26/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2003 42 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 2/4/2008 Male 3/16/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 3/22/2010 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 2/4/2008 59 Male 3/22/2010 Physician Germany
Primary
Secondary
Systemic Lupus Erythematosus Hospitalization 3/15/2009 Female 3/25/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 3/31/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2005 64 Female 4/14/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2008 62 Male 6/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 64 Female 6/15/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 2/4/2008 59 Male 9/16/2010 Physician Germany
Primary
Secondary
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 44 Male 452 lb 11/9/2010 Lawyer United States
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization Female 12/2/2010 Physician Netherlands
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 2/4/2008 59 Male 3/22/2010 Physician Germany
Primary
Secondary
Sepsis Other Serious 10/9/2010 79 Female 227 lb 12/16/2010 Other Health Professional France
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 50 Male 262 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 10/9/2010 79 Female 227 lb 12/21/2010 Other Health Professional France
Primary
Concomitant
Urticaria Other Serious 12/8/2010 35 Female 128 lb 1/5/2011 Pharmacist Portugal
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 2/4/2008 59 Male 1/19/2011 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/4/2008 59 Male 1/25/2011 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 9/30/2010 79 Female 227 lb 2/23/2011 Other Health Professional France
Primary
Concomitant
General Physical Health Deterioration Hospitalization 9/30/2010 79 Female 227 lb 3/1/2011 Other Health Professional France
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Abnormal Other Serious 1/1/2008 62 Male 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 4/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 9/29/2010 79 Female 227 lb 4/20/2011 Other Health Professional France
Primary
Concomitant
Pulmonary Fibrosis Death 2/27/2011 60 Female 187 lb 5/10/2011 Physician Germany
Primary
Concomitant
Drug Interaction Hospitalization 10/7/2010 67 Male 6/6/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Drug Interaction Hospitalization 7/1/2010 67 Male 6/7/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Condition Aggravated Life Threatening 7/1/2010 67 Male 6/7/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Rhabdomyolysis Life Threatening 7/1/2010 67 Male 6/7/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting

Drug Data