Fluconazole combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Death 9/24/2003 64 Male 12/30/2005 Japan
Primary
Concomitant
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 1/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 2/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 11/3/2005 35 Male 170 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1 Female 2/6/2006
Primary
Secondary
Concomitant
Post Procedural Complication Death 34 Male 2/7/2006 Physician Japan
Primary
Concomitant
Tremor Hospitalization 2 Female 2/14/2006 Physician Italy
Primary
Concomitant
Hemiplegia Death 34 Male 2/16/2006 Physician Japan
Primary
Concomitant
Tremor Hospitalization 1 Female 3/3/2006 Consumer United States
Primary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Death 1/9/2006 85 Male 167 lb 3/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/1/2005 26 Male 110 lb 4/4/2006 Physician Japan
Primary
Concomitant
Urine Output Decreased Life Threatening 3/27/2006 47 Female 134 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Death 9/24/2003 64 Male 4/3/2006 Japan
Primary
Concomitant
Sternal Fracture Other Serious 6/5/2005 57 Male 4/11/2006 Physician Netherlands
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 3/8/2006 52 Male 5/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Death 9/24/2003 64 Male 5/31/2006 Japan
Primary
Concomitant
Human Herpesvirus 6 Infection Death 34 Male 5/23/2006 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 5/11/2005 53 Female 4/20/2006 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 3/24/2006 62 Male 6/6/2006 United Kingdom
Primary
Concomitant
Shock Death 46 Male 176 lb 6/15/2006 Physician Sweden
Primary
Secondary
Concomitant
Shock Death 46 Male 176 lb 6/22/2006 Sweden
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2006 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Life Threatening 3/27/2006 47 Female 134 lb 5/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hepatitis Cholestatic Life Threatening 4/20/2006 53 Male 121 lb 7/25/2006 Physician France
Primary
Concomitant
Shock Other Serious 46 Male 176 lb 7/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Neutropenia 4/11/2006 71 Female 143 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2006 Female 110 lb 8/11/2006 Physician Belgium
Primary
Secondary
Concomitant
Shock Death 11/23/2005 46 Male 8/30/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Respiratory Depression Death 46 Male 176 lb 9/15/2006 Other Health Professional Sweden
Primary
Concomitant
Interacting
Postictal State Other Serious 9/5/2006 68 Female 114 lb 9/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 9/10/2006 47 Female 266 lb 9/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Other Serious 46 Male 176 lb 9/14/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 10/2/2006 Physician United States
Primary
Secondary
Concomitant
Patent Ductus Arteriosus Disability 8/29/2006 0 Male 10/4/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Neonatal Disability 8/29/2006 1 Male 10/9/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 10/11/2006 Physician United States
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 8/26/2006 66 Female 159 lb 10/12/2006 Pharmacist United States
Primary
Concomitant
Somnolence Death 7/11/2006 Male 146 lb 10/20/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/10/2006 74 Male 175 lb 10/19/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 10/26/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/10/2006 74 Male 175 lb 10/31/2006 Other Health Professional United States
Primary
Concomitant
Pancytopenia Required Intervention 9/5/2006 60 Female 11/2/2006 Pharmacist United States
Primary
Concomitant
Hepatitis Other Serious 6/29/2006 64 Female 123 lb 11/9/2006 United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Other Serious 11/1/2006 44 Male 11/13/2006 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Other Serious 11/29/2005 55 Male 152 lb 12/12/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 12/15/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 3/29/2006 64 Female 130 lb 7/31/2006 Pharmacist United States
Primary
Concomitant
Infusion Related Reaction 11/3/2006 Male 184 lb 1/22/2007 Pharmacist United States
Primary
Concomitant
Transplant Rejection Hospitalization 12/28/2006 50 Female 110 lb 2/8/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/10/2006 60 Female 146 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pancytopenia Death 3/10/2007 37 Female 165 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Required Intervention 3/19/2007 Female 4/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Other Serious 46 Male 5/22/2007 Pharmacist United States
Primary
Concomitant
Shock Death 46 Male 176 lb 5/15/2007 Sweden
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Other Serious 46 Male 6/22/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Ventricular Fibrillation Hospitalization 4/22/2007 Female 158 lb 7/11/2007 Physician United States
Primary
Secondary
Concomitant
Drug Prescribing Error Life Threatening 6/27/2007 Male 7/31/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Tremor Hospitalization 7/1/2007 66 Female 144 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 7/20/2007 11 Male 82 lb 8/3/2007 Other Health Professional Spain
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/22/2007 53 Female 174 lb 8/3/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2003 60 Male 428 lb 8/9/2007 Pharmacist United States
Primary
Concomitant
Drug Prescribing Error Life Threatening 6/27/2007 Male 8/15/2007 Physician United States
Primary
Concomitant
Vomiting Death 7/20/2007 11 Male 82 lb 8/13/2007 Physician Spain
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/1/2007 66 Female 144 lb 8/13/2007 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 7/12/2007 9 Male 8/14/2007 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 6/5/2007 58 Male 145 lb 8/22/2007 Pharmacist United States
Primary
Concomitant
Hepatomegaly Other Serious 6/27/2007 Male 8/27/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 7/20/2007 11 Male 82 lb 9/4/2007 Physician Spain
Primary
Concomitant
White Blood Cell Disorder Hospitalization 5/1/2007 62 Male 9/10/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 20 Male 9/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cardiotoxicity 1/18/2007 47 Female 180 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Renal Failure 3 lb 10/11/2007 Pharmacist United States
Primary
Concomitant
Cardiomyopathy Other Serious 6/27/2007 Male 10/25/2007 Physician United States
Primary
Secondary
Concomitant
Procedural Site Reaction Other Serious 20 Male 10/23/2007 Physician United States
Primary
Concomitant
Cardiomyopathy Other Serious 6/27/2007 Male 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Vaginal Candidiasis Required Intervention 8/25/2007 70 Female 10/24/2007 Physician Canada
Primary
Concomitant
Infection Life Threatening 7/8/2007 19 Male 164 lb 10/4/2007 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 6/27/2007 Male 11/9/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 20 Male 11/12/2007 Other Health Professional United States
Primary
Secondary
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Decreased Hospitalization 20 Male 11/14/2007
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cardiomyopathy Other Serious 6/27/2007 Male 11/26/2007 Physician United States
Primary
Secondary
Concomitant
Meningitis Enterococcal Hospitalization 11/10/2007 1 Female 11/16/2007 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/17/2007 61 11/23/2007 Physician Netherlands
Primary
Secondary
Concomitant
Meningitis Enterococcal Hospitalization 11/10/2007 1 Female 11/30/2007 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Transplant Failure Hospitalization 12/13/2007 53 Male 225 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
Self-medication Hospitalization 7/24/2007 41 Female 139 lb 11/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 1/21/2008 Female 21 lb 1/23/2008 United States
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2008 Female 21 lb 1/28/2008 Canada
Primary
Secondary
Concomitant
Renal Failure Male 3 lb 1/11/2008 Pharmacist United States
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2008 Female 21 lb 2/8/2008 United States
Primary
Secondary
Concomitant
Lymphoma Death 1/21/2008 31 Male 2/28/2008 Other Health Professional United States
Primary
Concomitant
Hepatic Failure Other Serious 12/5/2006 36 Female 2/22/2008 Spain
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 8/25/2003 Female 2/29/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 8/25/2003 Female 3/11/2008 Physician Germany
Primary
Secondary
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
Tinnitus Hospitalization 35 Male 143 lb 3/6/2008 Pharmacist United States
Primary
Concomitant
Swollen Tongue Death 11/4/2004 Female 3/14/2008 Germany
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 8/24/2007 53 Male 271 lb 3/17/2008 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 11 Male 3/29/2008 Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/28/2008 Male 4/1/2008 Physician Italy
Primary
Concomitant
Sinusitis Hospitalization 4/23/2007 9 Female 54 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 4/18/2008 Germany
Primary
Secondary
Concomitant
Rash Other Serious 3/1/2008 60 Male 197 lb 4/22/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/26/2007 Male 5/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 3/19/2008 60 Male 197 lb 5/5/2008 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/19/2008 60 Male 197 lb 5/7/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Male 5/13/2008
Primary
Concomitant
Septic Shock Hospitalization 12/1/2007 Male 124 lb 5/20/2008 Belgium
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/6/2008 58 Male 5/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 3/5/2008 Male 122 lb 5/23/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/6/2008 58 Male 5/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/1/2005 Male 5/27/2008 Other Health Professional Canada
Primary
Concomitant
Tricuspid Valve Disease Other Serious 3/20/2008 60 Male 197 lb 5/15/2008 Physician United States
Primary
Secondary
Concomitant
Peripheral Coldness Disability 3/14/2008 58 Male 165 lb 5/28/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/12/2007 Female 275 lb 6/3/2008 Physician United States
Primary
Concomitant
Pathological Gambling Hospitalization 1/1/2001 Female 187 lb 6/6/2008 Consumer United States
Primary
Concomitant
Streptococcal Sepsis Death 4/2/2008 47 Male 137 lb 6/2/2008 Physician United States
Primary
Secondary
Concomitant
Atrial Tachycardia Hospitalization 4/8/2008 59 Male 401 lb 6/11/2008 Physician Germany
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/26/2007 Male 6/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 6/12/2008 59 Male 6/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Fatigue Hospitalization 3/5/2008 Male 122 lb 7/3/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Death Death 6/15/2007 Male 7/8/2008 Physician Denmark
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 4/15/2008 58 Male 7/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/9/2008 50 Male 179 lb 7/17/2008 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 5/13/1999 Male 7/23/2008 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/28/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/30/2008 Poland
Primary
Concomitant
Thrombocytopenia Other Serious 20 Male 7/30/2008 Other Health Professional United States
Primary
Secondary
Pyrexia Other Serious 20 Male 7/30/2008 Other Health Professional United States
Primary
Secondary
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/1/2008 Poland
Primary
Concomitant
Sternal Fracture Other Serious 6/5/2005 57 Male 8/1/2008 Physician Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/22/2008 Poland
Primary
Concomitant
Pancytopenia Hospitalization 3/27/2008 Male 178 lb 8/22/2008 United States
Primary
Secondary
Concomitant

Drug Data